Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
36
datasets available to search
ShareScore release 0.9.0
Dataset results
36 results for “physiological development”
Physiological parameters for three farm animal species (cattle, sheep, and swine) as the basis for the development of generic physiologically based kinetic models
<p><strong>IMPORTANT : PLEASE DISREGARD VERSION 1 OF THIS UPLOAD SINCE IT INCLUDES ERRONEOUS INFORMATION.</strong></p> <p>This excel file (DOI: 10.5281/zenodo.3433224) provides physiological parameters and their inter-individual variability (mean, coefficient of variation, sample size) for three farm animal species: cattle (<em>Bos taurus</em>), sheep (<em>Ovis aries</em>), and swine (<em>Sus scrofa domesticus</em>). These physiological parameters were estimated based on the results of extensive literature searches and specific experimental data described in Lautz et al., (2020). This file is associated with R codes (DOI: 10.5281/zenodo.3432796) for generic PBK models, partition coefficient Quantitative Structure Activity Relationship (QSAR) models for each farm animal species and parameterisation of the model.</p> <p>The full data collection and implementation of the models using case studies are described in Lautz et al., 2020 (10.1016/j.toxlet.2019.10.008).</p>
Figure 2. Passion fruit species under different irrigation intervals. A. Passiflora gibertii with a 4 in Development and physiological aspects of three species of passion fruit submitted to water stress
Figure 2. Passion fruit species under different irrigation intervals. A. Passiflora gibertii with a 4-day interval; B. P. gibertii with a 8-day interval; C. P. gibertii with a 12-day interval; D. P. foetida with a 4-day interval; E. P. foetida with a 8-day interval; F. P. foetida with a 12-day interval; G. P. edulis with a 4-day interval; H. P. edulis with a 8-day interval; I. P. edulis with a 12-day interval. Bar = 30 cm.
Environmental heterogeneity shapes physiological traits in tropical direct-developing frogs
<p><span><span><span><span><span><span><span><span><span><span><span>1. Tropical ectotherm species tend to have narrower physiological limits than species from temperate areas. As a consequence, tropical species are considered highly vulnerable to climate change since minor temperature increases can push them beyond their physiological thermal tolerance. Differences in physiological tolerances can also be seen at finer evolutionary scales, such as among populations of ectotherm species along elevation gradients, highlighting the physiological sensitivity of such organisms.</span></span></span></span></span></span></span></span></span></span></span></p> <p><span><span><span><span><span><span><span><span><span><span><span>2. Here we analyze the influence of elevation and bioclimatic domains, defined by temperature and precipitation, on thermal sensitivities of a terrestrial direct-developing frog (<i>Craugastor loki)</i> in a tropical gradient. We address the following questions: <i>i</i>) Does preferred temperature vary with elevation and among bioclimatic domains? <i>ii</i>)<i> </i>Do thermal tolerance limits, i.e. critical thermal maximum and critical thermal minimum vary with elevation and bioclimatic domains?, and <i>iii</i>) Are populations from high elevations more vulnerable to climate warming? </span></span></span></span></span></span></span></span></span></span></span></p> <p><span><span><span><span><span><span><span><span><span><span><span>3. We found that along an elevation gradient body temperature decreases as environmental temperature increases. The preferred temperature tends to moderately increase with elevation within the sampled bioclimatic domains. Our results indicate that the ideal thermal landscape for this species is located at mid-elevations, where the thermal accuracy (<i>db</i>) and thermal quality of the environment (<i>de</i>) are suitable. The critical thermal maximum is variable across elevations and among the bioclimatic domains, decreasing as elevation increases. Conversely, the critical thermal minimum is not as variable as the critical thermal maximum. </span></span></span></span></span></span></span></span></span></span></span></p> <p><span><span><span><span><span><span><span><span><span><span><span>4. Populations from the lowlands may be more vulnerable to future increases in temperature. We highlight that the critical thermal maximum is related to high temperatures exhibited across the elevation gradient and within in each bioclimatic domain, therefore, it is a response to high environmental temperatures.</span></span></span></span></span></span></span></span></span></span></span></p>
Physiological parameters for four fish species (rainbow trout, zebra fish, fathead minnow and three-spined stickleback) as the basis for the development of generic physiologically-based kinetic models
<p>This excel file (DOI: 10.5281/zenodo.1414332) provides physiological parameters and their inter-individual variability (mean, coefficient of variation, sample size) for four fish species: rainbow trout (<em>Onchorhynchus mykiss</em>), zebrafish (<em>Danio rerio</em>), fathead minnow (<em>Pimephales promelas</em>), and three-spined stickleback (<em>Gasterosteus aculeatus</em>). These physiological parameters were estimated based on the results of extensive literature searches and specific experimental data described in Grech et al., (2018). </p> <p>This file is associated with R codes (DOI: 10.5281/zenodo.1414332) for generic PB-K models, partition coefficient Quantitative Structure Activity Relationship (QSAR) models for each fish species and parameterisation of model for males and females of each species separately.</p> <p>The full data collection and implementation of the models using case studies are described in Grech et al., 2018 (<a href="https://doi.org/10.1016/j.scitotenv.2018.09.163">https://doi.org/10.1016/j.scitotenv.2018.09.163</a>)</p>
Variation in oxidative status, but not structural and physiological development, associated with changing ontogenetic environments
<p><span>Despite the potential for temporally-dependent relationships between trait values and fitness (e.g., as juveniles approach life-stage transitions such as fledging), how developmental stage affects canalization (a measure of robustness to environmental variation) of morphological and physiological traits is rarely considered. To test the sensitivity of morphological and physiological traits to environmental variation in two developmental stages, we manipulated brood size at hatch in European starlings (<em>Sturnus vulgaris</em>) and cross-fostered chicks between enlarged and reduced broods approaching fledging.</span><span> We measured body size (mass, tarsus, wing length) and physiological state (aerobic capacity, oxidative status) at asymptotic mass on day 15, then cross-fostered chicks between 'high' and 'low' quality environments and assessed the same traits again on day 20, after five days of pre-fledging mass recession. Chicks in reduced broods were heavier at asymptotic mass and had lower reactive oxygen metabolites than enlarged broods, while structural size, aerobic capacity, and antioxidant capacity were unaffected by experimental brood size. The observed canalization of structural and physiological traits during early development was maintained after cross-fostering, during late development. However, in contrast to early development, antioxidant capacity approaching fledging appeared sensitive to environmental conditions, as trajectories varied by cross-fostering treatment. Elevated reactive oxygen metabolites observed after early development in enlarged brood chicks were maintained after cross-fostering, suggesting canalized development in low-quality environments could produce oxidative costs that carry over between life-stages, even when conditions improve. These data reveal trait-specific relationships between environmental conditions and development and highlight how natal environment effects may vary by developmental stage.</span></p>
Mate desertion affects offspring survival, development and physiology in a songbird with multiple parental strategies
Open the record for dataset details and reuse information.
Environmental heterogeneity shapes physiological traits in tropical direct-developing frogs
Open the record for dataset details and reuse information.
Variation in oxidative status, but not structural and physiological development, associated with changing ontogenetic environments
Open the record for dataset details and reuse information.
Data from: Antibiotics in hives and their effects on honey bee physiology and behavioral development
<p>Recurrent honey bee losses make it critical to understand the impact of human interventions, such as antibiotics use in apiculture. Antibiotics are used to prevent or treat bacterial infections in colonies. However, little is known about their effects on honey bee development. We studied the effect of two commercial beekeeping antibiotics on the bee physiology and behavior throughout development. Our results show that antibiotic treatments have an effect on amount of lipids and rate of behavioral development. Lipid amount in treated bees was higher than those not treated. Also, the timing of antibiotic treatment had distinct effects for the age of onset of behaviors starting with cleaning, then nursing and lastly foraging. Bees treated during larva-pupa stages demonstrated an accelerated behavioral development and loss of lipids, while bees treated from larva to adulthood had a delay in behavioral development and loss of lipids. The effects were shared across the two antibiotics tested, Terramycin<sup>R</sup> (oxytetracycline) and Tylan<sup>R</sup> (tylosin tartrate). These results on effects of antibiotic treatments suggest a role of microbiota in the interaction between the fat body and brain that is important for honey bee behavioral development.</p>
Raw data and correlation analysis of physiological data sampled from Atlantic halibut (Hippoglossus hippoglossus) for the development of a PBPK model
<p>Raw data sampled from Atlantic halibut <em>(Hippoglossus hippoglossus)</em> for the characterization of physiological parameters for the development of a species-specific physiology-based pharmacokinetic (PBPK) model. Additionally, the document containes imputed data for a PCA analysis and correlation coefficients and the related p-values from a correlation analysis. </p>
Development of Novel Physiological CMR Methods in Health and Disease
ClinicalTrials.gov study NCT03854071. IPD Sharing: UNDECIDED. Countries: 1. Publications: 24.
Developing a Treatment Clustering System for Obstructive Sleep Apnea Using Polysomnographic Physiological Signals
ClinicalTrials.gov study NCT06512779. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Moss growth, development, morphology, and physiology dataset and code
Open the record for dataset details and reuse information.
Data from: Antibiotics in hives and their effects on honey bee physiology and behavioral development
Open the record for dataset details and reuse information.
Data from: Coordination of wing and whole body development at developmental milestones ensures robustness against environmental and physiological perturbations
Development produces correctly patterned tissues under a wide range of conditions that alter the rate of development in the whole body. We propose two hypotheses through which tissue patterning could be coordinated with whole body development to generate this robustness. Our first hypothesis states that tissue patterning is tightly coordinated with whole body development over time. The second hypothesis is that tissue patterning aligns at developmental milestones. To distinguish between our two hypotheses, we developed a staging scheme for the wing imaginal discs of Drosophila larvae using the expression of canonical patterning genes, linking our scheme to three whole body developmental events, moulting, larval wandering and pupariation. We used our scheme to explore how the progression of pattern changes when developmental time is altered either by changing temperature or by altering the timing of hormone synthesis that drives developmental progression. We found the expression pattern in the wing disc always aligned at moulting and pupariation, indicating that these key developmental events represent milestones. Between these milestones, the progression of pattern showed greater variability in response to changes in temperature and alterations in physiology. Furthermore, our data showed that discs from wandering larvae had greater variability in their patterning stage. Thus, for wing disc patterning wandering does not appear to be a developmental milestone. Our findings reveal that tissue patterning remains robust against environmental and physiological perturbations by aligning at developmental milestones. Furthermore, our work provides an important glimpse into how the development of individual tissues is coordinated with the body as a whole.
Data from: A qualitative study on the development and rectification of advanced medical students' misconceptions about the physiological electrocardiogram (ECG)
<p><strong>Purpose:</strong> The study takes a qualitative and explorative approach to capture the concepts that German medical students have of the physiological electrocardiogram (ECG) which they acquired during their preclinical training. These concepts are then considered for possible misconceptions. Afterwards a theory-based intervention which allows subjects to see the connection of the curve progression with the spatial spreading of excitation (animated vector loop) is put to the test.</p> <p><strong>Methods:</strong> In the course of a diagnosis of learning potentials, individual students participated in problem-centred, guided interviews. The developed intervention was tested in separately conducted teaching experiments using thinking aloud protocols. The data evaluation was done through qualitative content analysis. Based on the conceptual metaphor theory, conceptions and their underlying embodied cognition were analysed.</p> <p><strong>Results: </strong>One of the subjects' typical misinterpretations is taking the progression of the ECG tracing for a mere increase and decrease of the myocardium's electrical activity, rather than connecting it with its spatial and temporal aspects. The data evaluation has shown that the newly developed theory-based intervention can lead to re-learning. Reconstructed metaphorical concepts illustrate this process of understanding. It is exemplarily shown how, through the course of the interviews, students are enabled to appropriately explain ECGs as the two-dimensional representation of the spatial excitation propagation in the heart.</p> <p><strong>Conclusion: </strong>By capturing typical misconceptions of the physiological electrocardiogram and demonstrating interventions that support learning, the study provides a contribution to comprehensive learning which can be used in the basic education of medical students.</p>
Figure 1. r in Development and physiological aspects of three species of passion fruit submitted to water stress
Figure 1. r values of Pearson correlation between the variables analyzed in the passion fruit species after the irrigation intervals.
Monitoring Physiologic Data in the Development of Pressure Ulcers
ClinicalTrials.gov study NCT02689817. IPD Sharing: NO. Countries: 0. Publications: 16.
Data from: The role of ontogeny in physiological tolerance: decreasing hydrostatic pressure tolerance with development in the northern stone crab Lithodes maja
Open the record for dataset details and reuse information.
Data from: A qualitative study on the development and rectification of advanced medical students’ misconceptions about the physiological electrocardiogram (ECG)
Open the record for dataset details and reuse information.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.