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4 results for “pig microbiome”
Domestication shapes the pig gut microbiome and immune traits from the scale of lineage to population
<p><span>Animal ecology and evolution have long been known to shape host physiology, but more recently, the gut microbiome has been identified as a mediator between animal ecology and evolution and health</span><span>. The gut microbiome has been shown to differ between wild and domestic animals, but the role of these differences for domestic animal evolution remains unknown. </span><span>Gut microbiome responses to new animal genotypes and local environmental change during domestication may promote specific host phenotypes that are adaptive (or not) to the domestic environment. Because the gut microbiome supports host immune function, understanding the effects of animal ecology and evolution on the gut microbiome and immune phenotypes is </span><span>critical. </span><span>We investigated how domestication affects the gut microbiome and host immune state in multiple pig populations across five domestication contexts representing domestication status and current living conditions: free-ranging wild, captive wild, free-ranging domestic, captive domestic in research or industrial settings. We observed that domestication context explained much of the variation in gut microbiome composition, pathogen abundances, and immune markers, yet the main differences in the repertoire of metabolic genes found in the gut microbiome were between the wild and domestic genetic lineages. We also documented population-level effects within domestication contexts, demonstrating that fine scale environmental variation also shaped host and microbe features. Our findings highlight that understanding </span><span>which gut microbiome and immune traits respond to host genetic lineage and/or scales of local ecology could inform </span><span>targeted interventions that manipulate the gut microbiome to achieve beneficial health outcomes. </span></p>
Domestication shapes the pig gut microbiome and immune traits from the scale of lineage to population
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PIBAC: Extensive cultivation of the pig gut microbiome identifies novel bacterial diversity and functions and enables tailored functional studies
<p>In-depth cultivation of the pig gut microbiome towards novel bacterial diversity and tailored functional studies:</p> <ul> <li>780 MAGs from all-in-one assembly of 295 pig gut metagenomic samples (Xiao, 2016)</li> <li>38 isolates representing novel species (single draft genomes)</li> <li>representing in total 617 species (hqMAGs-dereplicated_genomes, comp>90%, con<5%</li> </ul> <p>More information you can find here:</p> <p>https://github.com/tillrobin/PIBAC</p> <p>https://www.dsmz.de/pibac</p> <p> </p> <p>External study providing data:</p> <p>Xiao, Liang, et al. "A reference gene catalogue of the pig gut microbiome." Nature microbiology 1.12 (2016): 16161. <a href="https://doi.org/10.1038/nmicrobiol.2016.161">https://doi.org/10.1038/nmicrobiol.2016.161</a> </p>
Resistant starch induces catabolic but suppresses immune and cell division pathways and changes the microbiome in proximal colon of male pigs
GEO Series GSE45554. Sus scrofa. 20 samples. Type: Expression profiling by array.
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Allen Brain Atlas
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.