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14
datasets available to search
ShareScore release 0.9.0
Dataset results
14 results for “polyQ”
Allele-specific quantitation of ATXN3 and HTT transcripts in polyQ disease models.
<p>Precise values obtained during the research that led to the publishing of scientific paper entitled 'Allele-specific quantitation of ATXN3 and HTT transcripts in polyQ disease models'.</p>
Full-length huntingtin constructs for eukaryotic expression of huntingtin protein with different polyQ lengths 2018/05/01
<p>Huntingtin structure-function open lab notebook project: Full-length huntingtin constructs for eukaryotic expression of huntingtin protein with different polyQ lengths 2018/05/01</p>
Differential static light scattering (DSLS) of full-length huntingtin samples of different polyQ lengths (Q19, Q23, Q42 and Q54) – 2018/05/09
<p><strong>Project</strong> - Huntingtin structure-function open lab notebook. </p> <p><strong>Experiment</strong> - Differential static light scattering (DSLS) of full-length huntingtin samples of different polyQ lengths (Q19, Q23, Q42 and Q54) – 2018/05/09. To investigate how increased polyQ length of the huntingtin protein affects its biophysical properties. </p> <p> </p>
fluorescence quantification associated with manuscript (Autophagy preferentially degrades non-fibrillar polyQ aggregates https://doi.org/10.1101/2023.08.08.552291 )
Open the record for dataset details and reuse information.
tomogram quantification related to manuscript (Autophagy preferentially degrades non-fibrillar polyQ aggregates) https://doi.org/10.1101/2023.08.08.552291
Open the record for dataset details and reuse information.
Differential static light scattering (DSLS) of huntingtin-HAP40 complex samples of different polyQ lengths (Q23 and Q54) – 2018/10/13
<p>Project - Huntingtin structure-function open lab notebook. </p> <p>Experiment - Differential static light scattering (DSLS) of huntingtin-HAP40 complex samples of different polyQ lengths (Q23 and Q54) - 2018/10/13. To investigate how increased polyQ length of the huntingtin protein and complex formation of HAP40 might affect thermal aggregation properties of the samples. </p>
Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations [RNA-seq]
GEO Series GSE118088. Homo sapiens. 19 samples. Type: Expression profiling by high throughput sequencing.
Differential roles for DNAJ isoforms in HTT-polyQ and mutant FUS aggregation modulation revealed by chaperone network screens
GEO Series GSE165317. Homo sapiens. 35 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomics profile of polyQ expressing U2OS cells and clofazimine treated polyQ expressing U2OS cells
GEO Series GSE222758. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
The polymorphic PolyQ tail protein of the Mediator Complex, Med15, regulates variable response to stress
GEO Series GSE129898. Saccharomyces cerevisiae. 48 samples. Type: Expression profiling by high throughput sequencing.
Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations
GEO Series GSE118325. Homo sapiens. 27 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations [ChIP-seq]
GEO Series GSE118324. Homo sapiens. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Contribution of Nuclear and Extranuclear PolyQ to Neurological Phenotypes in Mouse Models of Huntington’s Disease
GEO Series GSE3248. Mus musculus. 48 samples. Type: Expression profiling by array.
pH modulation restores proteostasis and extend lifespan in a yeast model of Huntington’s Disease [polyQ]
GEO Series GSE297008. Saccharomyces cerevisiae. 6 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
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Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.