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Dataset results
15 results for “polyclonal antibodies”
Supplementary data - Simultaneous polyclonal antibody sequencing and epitope mapping by cryo electron microscopy and mass spectrometry – a perspective
<p>Analysis files and scripts for <a href="https://doi.org/10.1101/2024.06.21.600107" target="_blank" rel="noopener">associated manuscript</a>. </p> <ul> <li>CR3022.zip: script (in Rust) and necessary data to run said script for CR3022 analysis with the results from running the script.</li> <li>MA-analysis-script.zip: script (in Rust) and necessary data to run said script for automated analysis of MA benchmark results.</li> <li>MA-analysis-data.zip: data from running the MA-analysis-script, containing all MA and Stitch output files.</li> <li>MA-analysis-data-EMPEM.zip: data from running MA and Stitch on the EMPEM benchmark.</li> </ul>
Underlying dataset for figures published in "A tool for evaluating heterogeneity in avidity of polyclonal antibodies"
<p>The dataset consists of all underlying data associated with Li et al. Front Immunol. 2023, 16;14:1049673. (doi: 10.3389/fimmu.2023.1049673.). Each folder corresponds to data shown in a single figure, with the figure number indicated in the folder names. Please refer to the ReadMe.pdf for information on the content of the figure-specific folders.</p>
Recombinant Hyperimmune Polyclonal Antibody (GIGA-2050) in COVID-19 Patients
ClinicalTrials.gov study NCT04883138. IPD Sharing: NO. Countries: 1. Publications: 1.
Observational Study to Evaluate the Safety and Efficacy of Polyclonal Antibodies in Simultaneous Pancreas Kidney Transplant Recipients
ClinicalTrials.gov study NCT03470961. IPD Sharing: NO. Countries: 1. Publications: 2.
Transcriptomic profiling of purified polyclonal anti-dsDNA antibodies stimulated human mesangial cells
GEO Series GSE80364. Homo sapiens. 6 samples. Type: Expression profiling by array.
Hsf1 Chip on chip on wildtype(WT) and iron deprived (BPS) cells of Candida albicans using polyclonal antibody
GEO Series GSE110889. Candida albicans. 4 samples. Type: Genome binding/occupancy profiling by array.
Data from: Mapping polyclonal HIV-1 antibody responses via next-generation neutralization fingerprinting
Computational neutralization fingerprinting, NFP, is an efficient and accurate method for predicting the epitope specificities of polyclonal antibody responses to HIV-1 infection. Here, we present next-generation NFP algorithms that substantially improve prediction accuracy for individual donors and enable serologic analysis for entire cohorts. Specifically, we developed algorithms for: (a) selection of optimized virus neutralization panels for NFP analysis, (b) estimation of NFP prediction confidence for each serum sample, and (c) identification of sera with potentially novel epitope specificities. At the individual donor level, the next-generation NFP algorithms particularly improved the ability to detect multiple epitope specificities in a sample, as confirmed both for computationally simulated polyclonal sera and for samples from HIV-infected donors. Specifically, the next-generation NFP algorithms detected multiple specificities in twice as many samples of simulated sera. Further, unlike the first-generation NFP, the new algorithms were able to detect both of the previously confirmed antibody specificities, VRC01-like and PG9-like, in donor CHAVI 0219. At the cohort level, analysis of ~150 broadly neutralizing HIV-infected donor samples suggested a potential connection between clade of infection and types of elicited epitope specificities. Most notably, while 10E8-like antibodies were observed in infections from different clades, an enrichment of such antibodies was predicted for clade B samples. Ultimately, such large-scale analyses of antibody responses to HIV-1 infection can help guide the design of epitope-specific vaccines that are tailored to take into account the prevalence of infecting clades within a specific geographic region. Overall, the next-generation NFP technology will be an important tool for the analysis of broadly neutralizing polyclonal antibody responses against HIV-1.
Data from: Mapping polyclonal HIV-1 antibody responses via next-generation neutralization fingerprinting
Open the record for dataset details and reuse information.
Ncb2 ChIP-chip on Gu4 (azole susceptible, AS) and Gu5 (azole resistant, AR) cells of Candida albicans using polyclonal antibody
GEO Series GSE76858. Candida albicans. 6 samples. Type: Genome binding/occupancy profiling by array.
ENCODE ChIP-chip for Rel A (p65) using polyclonal antibody (N-) on TNF-alpha-stimulated HeLaS3 Cells [unpublished]
GEO Series GSE6900. Homo sapiens. 3 samples. Type: Genome binding/occupancy profiling by genome tiling array.
ENCODE ChIP-chip for RNA Polymerase II using polyclonal antibody on GM06990 Cells [unpublished]
GEO Series GSE6392. Homo sapiens. 3 samples. Type: Genome binding/occupancy profiling by genome tiling array.
ENCODE ChIP-chip for Rel A (p65) using polyclonal antibody (C-20) on TNF-alpha-stimulated HeLaS3 Cells [unpublished]
GEO Series GSE6899. Homo sapiens. 3 samples. Type: Genome binding/occupancy profiling by genome tiling array.
ENCODE ChIP-chip for RNA Polymerase II using polyclonal antibody (N-20) on HeLaS3 Cells [unpublished]
GEO Series GSE6390. Homo sapiens. 3 samples. Type: Genome binding/occupancy profiling by genome tiling array.
Deciphering Mycobacterium tuberculosis glycan epitopes through clustering of human polyclonal and isolating novel monoclonal antibodies II
GEO Series GSE263497. synthetic construct; Homo sapiens. 11 samples. Type: Protein profiling by protein array.
Deciphering Mycobacterium tuberculosis glycan epitopes through clustering of human polyclonal and isolating novel monoclonal antibodies I
GEO Series GSE263496. synthetic construct; Homo sapiens. 107 samples. Type: Protein profiling by protein array.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.