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Dataset results
8 results for “population-based model”
Evaluating the role of the nuclear microenvironment in gene function by population-based modeling
<p>This repository accompanies the manuscript "<strong>Evaluating the role of the nuclear microenvironment in gene function by population-based modeling</strong>", available in <em>Nature Structural & Molecular Biology</em>.</p> <p>It contains the files for the population of 3D structures for GM12878 in 200-kb resolution generated using IGM (https://github.com/alberlab/igm) and the derived structural features. Please see README.txt for more information.</p> <p>For any inquiries please reach out to Dr. Frank Alber (falber@g.ucla.edu).</p>
Simulated population time series used to build and test a model of accuracy for population-based global biodiversity indicators
<p class="MsoNormal">Global biodiversity is facing a crisis, which must be solved through effective policies and on-the-ground conservation. But governments, NGOs, and scientists need reliable indicators to guide research, conservation actions, and policy decisions. Developing reliable indicators is challenging because the data underlying those tools is incomplete and biased. For example, the Living Planet Index tracks the changing status of global vertebrate biodiversity, but taxonomic, geographic and temporal gaps and biases are present in the aggregated data used to calculate trends. But without a basis for real-world comparison, there is no way to directly assess an indicator's accuracy or reliability. Instead, a modelling approach can be used.</p> <p class="MsoNormal">We developed a model of trend reliability, using simulated datasets as stand-ins for the "real world", degraded samples as stand-ins for indicator datasets (e.g. the Living Planet Database), and a distance measure to quantify reliability by comparing sampled to unsampled trends. The model revealed that the proportion of species represented in the database is not always indicative of trend reliability. Important factors are the number and length of time series, as well as their mean growth rates and variance in their growth rates, both within and between time series. We found that many trends in the Living Planet Index need more data to be considered reliable, particularly trends across the global south. In general, bird trends are the most reliable, while reptile and amphibian trends are most in need of additional data. We simulated three different solutions for reducing data deficiency, and found that collating existing data (where available) is the most efficient way to improve trend reliability, and that revisiting previously-studied populations is a quick and efficient way to improve trend reliability until new long-term studies can be completed and made available.</p>
Simulated population time series used to build and test a model of accuracy for population-based global biodiversity indicators
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Supplemental Materials - Performance Figures for "A Model for Predicting the (re)-occurrence of a ≥40% eGFR Decline in a large Population-based cohort of Persons with or At-Risk of Chronic Kidney Disease " paper
<p>The zip file contains performance metrics figures for each dynamic Bayesian Network (DBN) model, stratified by comorbidities, race, CKD stages, and ethnicity.</p> <p>Contains:</p> <ul> <li>Stratified: Bootstrapping of 1000 iterations and 1000 samples with stratified proportions (as in the original population of the test set) of rapid eGFR decliners and non-decliners.</li> </ul> <p> </p> <p>Second zip contains DBN structures as matrices for 2 periods study entry to entry period and entry period to year 1 for all sites in 2 excel files.</p>
Data used for analysis in "Calibrating tropical forest coexistence in ecosystem demography models using multi-objective optimization through population-based parallel surrogate search"
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Antithrombotics' Therapeutic Optimization in Hospitalized Patients Using Physiologically- and Population-based Pharmacokinetic Modeling
ClinicalTrials.gov study NCT03477331. IPD Sharing: NO. Countries: 1. Publications: 4.
Dose Adaptation to Offset the Interaction Between Ticagrelor and Ritonavir by Population-based PK Modeling
ClinicalTrials.gov study NCT02435563. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Population-Based Modeling of Cholesterol Lowering in the United States
ClinicalTrials.gov study NCT00005463. IPD Sharing: Not stated. Countries: 0. Publications: 3.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.