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Dataset results
39 results for “postmortem brain”
Analysis of gene expression in the postmortem brain of neurotypical Black Americans reveals contributions of genetic ancestry: Source and Supplementary Data
<p><em><strong>Source and Supplementary data for AANRI manuscript</strong></em></p>
Re-Read Study to Compare the Brain Uptake of [18F]Flutemetamol With Brain Neuritic Plaque Density Determined Postmortem
ClinicalTrials.gov study NCT02090855. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Data from: Early postmortem brain MRI findings in COVID-19 non-survivors
<p class="normal"><span><span><span><span><span><span><span><span><span><span><span><i>Objectives: </i>The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is considered to have potential neuro-invasiveness that might lead to acute brain disorders or contribute to respiratory distress in patients with coronavirus disease 2019 (COVID-19). This study investigates the occurrence of structural brain abnormalities in non-survivors of COVID-19 in a virtopsy framework.</span></span></span></span></span></span></span></span></span></span></span></p> <p class="normal"><span><span><span><span><span><span><span><span><span><span><span><i>Methods: </i>In this prospective, monocentric, case series study, consecutive patients who fulfilled the following inclusion criteria benefited from an early postmortem structural brain MRI: death <24 hours, SARS-CoV-2 detection on nasopharyngeal swab specimen, chest computerized tomographic (CT) scan suggestive of COVID-19, absence of known focal brain lesion, and MRI compatibility. </span></span></span></span></span></span></span></span></span></span></span></p> <p class="normal"><span><span><span><span><span><span><span><span><span><span><span><i>Results</i>: Among the 62 patients who died from COVID-19 from 31/03/2020 to 24/04/2020 at our institution, 19 decedents fulfilled the inclusion criteria. Parenchymal brain abnormalities were observed in 4 decedents: subcortical micro- and macro-bleeds (2 decedents), cortico-subcortical edematous changes evocative of posterior reversible encephalopathy syndrome (PRES, one decedent), and nonspecific deep white matter changes (one decedent). Asymmetric olfactory bulbs were found in 4 other decedents without downstream olfactory tract abnormalities. No brainstem MRI signal abnormality was observed.</span></span></span></span></span></span></span></span></span></span></span></p> <p class="normal"><span><span><span><span><span><span><span><span><span><span><span><i>Conclusions: </i>Postmortem brain MRI demonstrates hemorrhagic and PRES-related brain lesions in non-survivors of COVID-19. SARS-CoV-2-related olfactory impairment seems to be limited to olfactory bulbs. Brainstem MRI findings do not support a brain-related contribution to respiratory distress in COVID-19. </span></span></span></span></span></span></span></span></span></span></span></p>
Data from: Early postmortem brain MRI findings in COVID-19 non-survivors
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5-hydroxymethylcytosine alterations in the human postmortem brains of autism spectrum disorder
GEO Series GSE107012. Homo sapiens. 36 samples. Type: Methylation profiling by high throughput sequencing.
Next-Generation Sequencing of Human Mitochondrial DNA (mtDNA) from Postmortem Brain and Blood
GEO Series GSE118615. Homo sapiens. 93 samples. Type: Genome variation profiling by high throughput sequencing.
Differential H3K9me2 heterochromatin levels and concordant mRNA expression in postmortem brain tissue of individuals with schizophrenia, bipolar, and controls
GEO Series GSE215991. Homo sapiens. 30 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Translatome analysis in postmortem brain-derived samples from Autism Spectrum Disorder affected individuals
GEO Series GSE236761. Homo sapiens. 20 samples. Type: Expression profiling by high throughput sequencing.
RNA sequencing of postmortem-fibroblast derived cell lines and postmortem human Brodmann Area 9 from Cocaine Use Disorder Subjects in the University of Texas Health Science Center at Houston Brain Col
GEO Series GSE224096. Homo sapiens. 33 samples. Type: Expression profiling by high throughput sequencing.
Single-nucleus transcriptomic analysis in the prefrontal cortex of postmortem human brain
GEO Series GSE205642. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Spatial transcriptomics n the postmortem brains of severe acute COVID19 [midbrain]
GEO Series GSE274938. Homo sapiens. 79 samples. Type: Other.
RNA sequencing analysis of postmortem human Brodmann Area 9 in the University of Texas Health Science Center at Houston Brain Collection
GEO Series GSE182321. Homo sapiens. 41 samples. Type: Expression profiling by high throughput sequencing.
Small RNA sequencing of postmortem human Brodmann Area 9 and postmortem human blood from Opioid Use Disorder Subjects and Controls in the University of Texas Health Science Center at Houston Brain Col
GEO Series GSE221515. Homo sapiens. 65 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Genome-wide Expression Assay Comparison Across Frozen and Fixed Postmortem Brain Tissue Samples
GEO Series GSE28475. Homo sapiens. 143 samples. Type: Expression profiling by array.
DNA methylation in postmortem brain samples from autism cases and controls
GEO Series GSE53162. Homo sapiens. 40 samples. Type: Methylation profiling by genome tiling array.
Profiling of miRNA transcriptomic changes using small RNA-seq in 8 regions of postmortem brains of subjects with alcohol use disorder
GEO Series GSE181520. Homo sapiens. 192 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Age, Sex and Alzheimer’s disease: a longitudinal study of 3xTg-AD mice reveals sex-specific disease trajectories and inflammatory responses mirrored in postmortem brains from Alzheimer’s patients
GEO Series GSE254970. Mus musculus. 77 samples. Type: Expression profiling by high throughput sequencing.
Differential expression of microRNAs in human postmortem brain tissues of MDMA addiction
GEO Series GSE104315. Homo sapiens. 8 samples. Type: Non-coding RNA profiling by array.
Spatial transcriptomics in the postmortem brains of severe acute COVID19 [Pons]
GEO Series GSE274933. Homo sapiens. 119 samples. Type: Other.
Comparison of Abnormal Cortical Development in Brain Malformations on Postmortem Imaging With Autopsy
ClinicalTrials.gov study NCT00686530. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.