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10 results for “primary mitral regurgitation”

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ClinicalTrials.gov24/100

Effectiveness and Safety of Mitral Valve Repair With the NeoChord DS1000 Artificial Chordae Delivery System Versus Conventional Surgery in Patients With Severe Primary Mitral Regurgitation Due to Isol

ClinicalTrials.gov study NCT02829749. IPD Sharing: NO. Countries: 1. Publications: 0.

closedIPD-NOFeb 2026View details →
ClinicalTrials.gov24/100

Outcomes of Patients tReated wIth Mitral Transcatheter Edge-to-edge Repair for Primary Mitral Regurgitation Registry

ClinicalTrials.gov study NCT05332782. IPD Sharing: NO. Countries: 3. Publications: 0.

closedIPD-NOFeb 2026View details →
ClinicalTrials.gov24/100

Multicentre Study of MITRACLIP® Transcatheter Mitral Valve Repair in Patients With Severe Primary Mitral Regurgitation Eligible for High-risk Surgery

ClinicalTrials.gov study NCT03271762. IPD Sharing: Not stated. Countries: 1. Publications: 0.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov24/100

Primary Mitral Regurgitation Repair

ClinicalTrials.gov study NCT04067635. IPD Sharing: Not stated. Countries: 1. Publications: 0.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov24/100

The Role of cardIac magNeTic rEsonance in surGical Decision Making in Patients With Severe pRimAry miTral rEgurgitation

ClinicalTrials.gov study NCT07366723. IPD Sharing: Not stated. Countries: 1. Publications: 0.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov24/100

Study for the Identification of Subclinical Atrial Fibrillation In Patients With Significant Primary Mitral Regurgitation

ClinicalTrials.gov study NCT07377799. IPD Sharing: NO. Countries: 1. Publications: 0.

closedIPD-NOFeb 2026View details →
ClinicalTrials.gov24/100

Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)

ClinicalTrials.gov study NCT05051033. IPD Sharing: YES. Countries: 5. Publications: 0.

controlledIPD-YESFeb 2026View details →
ClinicalTrials.gov20/100

Understanding the Metabolic and Functional Derangement of Primary Mitral Regurgitation: a Feasibility Study Using Carbon 11(C-11) Acetate Cardiac Positron Emission Tomography Magnetic Resonance Imagin

ClinicalTrials.gov study NCT04795856. IPD Sharing: NO. Countries: 0. Publications: 0.

closedIPD-NOFeb 2026View details →
ClinicalTrials.gov20/100

Effect of Significant Ischemic Mitral Regurgitation on the Outcome of ST Segment Elevation Myocardial Infarction Patients Treated With Primary Percutaneous Coronary Intervention

ClinicalTrials.gov study NCT04106648. IPD Sharing: Not stated. Countries: 0. Publications: 0.

restrictedIPD-UNDECIDEDFeb 2026View details →
zenodo12/100

Partial dataset related to the article "Prognostic Impact of Extra–Mitral Valve Cardiac Involvement in Patients With Primary Mitral Regurgitation"

<p>This record contains partial&nbsp;raw data related to the article &quot;Prognostic Impact of Extra&ndash;Mitral Valve Cardiac Involvement in Patients With Primary Mitral Regurgitation&quot;</p> <p>OBJECTIVES The aim of this study was to evaluate the prognostic impact of the presence of extra&ndash;mitral valve cardiac</p> <p>involvement (including known risk factors but also severe left atrial [LA] dilatation and right ventricular [RV] dysfunction)</p> <p>in a large multicenter study of patients with primary mitral regurgitation (MR).</p> <p>BACKGROUND In patients with severe primary MR, the indication for surgery is currently based on the presence of</p> <p>symptoms, left ventricular dilatation and dysfunction, atrial fibrillation, and pulmonary hypertension.</p> <p>METHODS Patients with severe primary MR undergoing surgery were included and categorized according to the extent</p> <p>(highest) of cardiac involvement: group 0, no cardiac involvement; group 1, left ventricular involvement; group 2, LA</p> <p>involvement; group 3, pulmonary vasculature or tricuspid valve involvement; or group 4, RV involvement. The outcome</p> <p>was all-cause mortality.</p> <p>RESULTS A total of 1,106 patients were included (mean age 63 12 years, 68% male). In total, 377 patients (34%)</p> <p>were classified in group 0, 239 (22%) in group 1, 213 (19%) in group 2, 180 (16%) in group 3, and 97 (9%) in group 4.</p> <p>Kaplan-Meier curve analysis revealed significantly worse survival (log-rank chi-square &frac14; 43.4; P &lt; 0.001) with higher</p> <p>group. On multivariable analysis, age, male sex, chronic obstructive pulmonary disease, kidney function, and group of</p> <p>cardiac involvement were independently associated with all-cause mortality. For each increase in group, a 17% higher risk</p> <p>for all-cause mortality was observed (95% CI: 1.051-1.313; P &frac14; 0.005) during a median follow-up time of 88 months.</p> <p>CONCLUSIONS In patients with severe primary MR, a novel classification system based on extra&ndash;mitral valve cardiac</p> <p>involvement may help refine risk stratification and timing of surgery, particularly including severe LA dilatation and RV</p> <p>dysfunction in the assessment.</p>

restrictedJan 2023View details →

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International Brain Laboratory public data

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Last verified 2026-04-29Open record

OpenNeuro

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neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record