Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
176
datasets available to search
ShareScore release 0.9.0
Dataset results
176 results for “procalcitonin”
Procalcitonin detection in human plasma specimens using a fast version of proximity extension assay.
<p>Proximity Extension Assay (PEA), an homogeneous, dual-recognition immunoassay, has proven to be sensitive, specific and convenient for detection or quantitation of one or multiple analytes in human plasma. In this paper, the PEA principle was applied to the detection of procalcitonin (PCT), a widely used biomarker for the identification of bacterial infection. A simple, short PEA protocol, with an assay time suitable for point-of-care diagnostics, is presented here as a proof of concept. Pairs of oligonucleotides and monoclonal antibodies were selected to generate tools specifically adapted to the development of an efficient PEA for PCT detection. The assay time was reduced by more than 13-fold compared to published versions of PEA, without significantly affecting assay performance. It was also demonstrated that T4 DNA polymerase could advantageously be replaced by other polymerases having strong 3’>5’ exonuclease activity. The sensitivity of this improved assay was determined to be about 0.1 ng/mL of PCT in plasma specimen.</p>
Candidate High-Resolution Mass Spectrometry-Based Reference Method for the Quantification of Procalcitonin in Human Serum Using a Characterized Recombinant Protein as a Primary Calibrator
<p>Dataset related to Huu-Hien Huynh, Vincent Delatour, Maxence Derbez-Morin, Qinde Liu, Amandine Boeuf, and Joëlle Vinh, (2022) Candidate High-Resolution Mass Spectrometry-Based Reference Method for the Quantification of Procalcitonin in Human Serum Using a Characterized Recombinant Protein as a Primary Calibrator. Anal. Chem. 2022, 94, 10, 4146–4154.</p>
Placebo-Controlled Trial of Antibiotic Therapy in Adults With Suspect Lower Respiratory Tract Infection (LRTI) and a Procalcitonin Level
ClinicalTrials.gov study NCT03341273. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Procalcitonin Antibiotic Consensus Trial (ProACT)
ClinicalTrials.gov study NCT02130986. IPD Sharing: Not stated. Countries: 1. Publications: 23.
Evaluation of the Clinical Relationship Between Procalcitonin Level and Bacteremia Agent in Intensive Care Unit Patients
ClinicalTrials.gov study NCT06958354. IPD Sharing: YES. Countries: 1. Publications: 3.
Impact of a Procalcitonin Testing and Treatment Algorithm on Antibiotic Use and Outcomes in the Pediatric Intensive Care Unit
ClinicalTrials.gov study NCT03440918. IPD Sharing: NO. Countries: 1. Publications: 1.
PHASE II SINGLE-CENTER, RANDOMIZED, OPEN-LABEL, PROSPECTIVE, STUDY TO DETERMINE THE IMPACT OF SERIAL PROCALCITONIN
ClinicalTrials.gov study NCT04983901. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Differentiating causes of febrile illness in Burkina Faso: data from an accuracy study comparing gold standard culture techniques with a haemocytometry based algorithm (IMS), procalcitonin (PCT) and C-reactive protein (CRP)
Open the record for dataset details and reuse information.
An Investigation of the Effect of Types of Catheters on Bloodstream Infection in Patients With Major Burns: Prediction With Procalcitonin and Prognosis
ClinicalTrials.gov study NCT05581316. IPD Sharing: NO. Countries: 1. Publications: 1.
KInetics of Procalcitonin to Reduce Unnecessary aNtibiotic Use - Comparing Procalcitonin Kinetics-guided and Absolute Procalcitonin Value-guided Antibiotic Initiation in Reducing Unnecessary Antibioti
ClinicalTrials.gov study NCT07211620. IPD Sharing: YES. Countries: 1. Publications: 14.
Procalcitonin Monitoring May Decrease Antibiotic Use in the Intensive Care Unit
ClinicalTrials.gov study NCT01085994. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Neonatal Procalcitonin Intervention Study
ClinicalTrials.gov study NCT00854932. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Procalcitonin as a Marker of Infection in Cancer Patients
ClinicalTrials.gov study NCT01227109. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Use Of Procalcitonin Level For Guidance of The Treatment of Suspected Community Acquired Pneumonia
ClinicalTrials.gov study NCT00914550. IPD Sharing: Not stated. Countries: 1. Publications: 8.
Procalcitonin in Early Antibiotic Interruption in Patient With Bacterial Pulmonary infeCtion and Acute Heart Failure
ClinicalTrials.gov study NCT02787603. IPD Sharing: UNDECIDED. Countries: 1. Publications: 5.
Procalcitonin at Zero and 24 Hours as a Prognostic Factor in Patients With Pneumonia
ClinicalTrials.gov study NCT03711227. IPD Sharing: NO. Countries: 1. Publications: 22.
Procalcitonin in Diagnosis of Bacterial Infections in Young Infants
ClinicalTrials.gov study NCT03509727. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Procalcitonin-guided Treatment on Duration of Antibiotic Therapy and Cost in Septic Patients
ClinicalTrials.gov study NCT02202941. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Petechiae In Children (PIC) Study: Defining A Clinical Decision Rule for The Management Of Fever and Non-Blanching Rashes In Children Including The Role Of Point Of Care Testing For Procalcitonin & Ne
ClinicalTrials.gov study NCT03378258. IPD Sharing: YES. Countries: 1. Publications: 12.
Establishment of an ELISA for the Recognition of Procalcitonin Variants in Patients With Hyperprocalcitonemia.
ClinicalTrials.gov study NCT05703802. IPD Sharing: NO. Countries: 1. Publications: 4.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.