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603 results for “progesterone”
Progesterone signaling in oviductal epithelial cells modulates the immune response to support preimplantation embryonic development
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Dataset for: Estimating pregnancy rate from blubber progesterone levels of a blindly biopsied beluga population poses methodological, analytical and statistical challenges
<p class="MsoBodyText"><span>Beluga (<em>Delphinapterus leucas</em>) from the St. Lawrence Estuary, Canada, have been declining since the early 2000s, suggesting recruitment issues as a result of low fecundity, abnormal abortion rates or poor calf or juvenile survival. Pregnancy is difficult to observe in cetaceans, making the ground-truthing of pregnancy estimates in wild individuals challenging. Blubber progesterone concentrations were contrasted among 62 SLE beluga with a known reproductive state (i.e., pregnant, resting, parturient, and lactating females), that were found dead in 1997–2019. The suitability of a threshold obtained from decaying carcasses to assess reproductive state and pregnancy rate of freshly-dead or free-ranging and blindly-sampled beluga was examined using three statistical approaches and two datasets (135 freshly-harvested carcasses in Nunavik, and 65 biopsy-sampled SLE beluga). Progesterone concentrations in decaying carcasses were considerably higher in known-pregnant (mean </span><span>±</span><span> sd: </span><span>365 </span><span>±</span><span> 244 ng g<sup>-1</sup> of tissue) </span><span>than resting (</span><span>3.1 </span><span>±</span><span> 4.5 ng g<sup>-1</sup> of tissue</span><span>) or lactating (</span><span>38.4 </span><span>±</span><span> 100 ng g<sup>-1</sup> of tissue</span><span>) females. An approach based on statistical mixtures of distributions and a logistic regression was compared to the commonly-used, fixed threshold approach (here, 100 ng g<sup>-1</sup>) for discriminating pregnant from non-pregnant females. The error rate for classifying individuals of known reproductive status was the lowest for the fixed threshold and logistic regression approaches, but the mixture approach required limited <em>a priori</em> knowledge for clustering individuals of unknown pregnancy status. Mismatches in assignations occurred at lipid content <10% of sample weight. Our results emphasize the importance of reporting lipid contents and progesterone concentrations in both units (ng g<sup>-1 </sup>of tissue and ng g<sup>-1</sup> of lipid) when sample mass is low. By highlighting ways to circumvent potential biases in field sampling associated with capturability of different segments of a population, this study also enhances the usefulness of the technique for estimating pregnancy rate of free-ranging population. </span></p>
Blocking Mifepristone Action With Progesterone
ClinicalTrials.gov study NCT03774745. IPD Sharing: NO. Countries: 1. Publications: 1.
Zoledronic Acid - Letrozole Adjuvant Synergy Trial (ZFAST) - Cancer Treatment Related Bone Loss in Postmenopausal Women With Estrogen Receptor Positive and/or Progesterone Receptor Positive Breast Can
ClinicalTrials.gov study NCT00050011. IPD Sharing: Not stated. Countries: 2. Publications: 1.
Comparing IM vs. Vaginal Progesterone for Pre-term Birth
ClinicalTrials.gov study NCT00579553. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Randomized Trial of Maternal Progesterone Therapy
ClinicalTrials.gov study NCT02133573. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Estradiol and Progesterone in Hospitalized COVID-19 Patients
ClinicalTrials.gov study NCT04865029. IPD Sharing: NO. Countries: 1. Publications: 29.
Efficacy and Safety Study of Intravenous Progesterone in Patients With Severe Traumatic Brain Injury
ClinicalTrials.gov study NCT01143064. IPD Sharing: Not stated. Countries: 21. Publications: 3.
Treatment of Uterine Fibroids With the Selective Progesterone Receptor Modulator CDB-2914
ClinicalTrials.gov study NCT00290251. IPD Sharing: Not stated. Countries: 1. Publications: 9.
Effect of Metformin on Sensitivity of the GnRH Pulse Generator to Suppression by Estradiol and Progesterone
ClinicalTrials.gov study NCT01427595. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Unique Effects of Perimenstrual Estradiol or Progesterone Supplementation on Perimenstrual Suicidality
ClinicalTrials.gov study NCT03498313. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Efficacy Study of a Cervical Pessary Containing Progesterone for the Prevention of Preterm Delivery
ClinicalTrials.gov study NCT02225353. IPD Sharing: NO. Countries: 1. Publications: 6.
A Study Comparing the Efficacy, Safety and Tolerability of Oral Dydrogesterone 30 mg Daily Versus Crinone 8% Intravaginal Progesterone Gel 90 mg Daily for Luteal Support in In-Vitro Fertilization (LOT
ClinicalTrials.gov study NCT02491437. IPD Sharing: Not stated. Countries: 10. Publications: 1.
Progesterone Treatment for Cocaine-dependent Women: A Pilot Study
ClinicalTrials.gov study NCT00632099. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Progesterone for Perimenopausal Night Sweats
ClinicalTrials.gov study NCT01464697. IPD Sharing: NO. Countries: 1. Publications: 1.
Progesterone vs Placebo Therapy for Women With Epilepsy
ClinicalTrials.gov study NCT00029536. IPD Sharing: Not stated. Countries: 2. Publications: 5.
Progesterone (17P, Makena®) for Prolongation of Pregnancy in Women With Preterm Rupture of the Membranes (PROM)
ClinicalTrials.gov study NCT01119963. IPD Sharing: Not stated. Countries: 1. Publications: 9.
A Safety and Efficacy Study of the Combination Estradiol and Progesterone to Treat Vasomotor Symptoms
ClinicalTrials.gov study NCT01942668. IPD Sharing: Not stated. Countries: 1. Publications: 13.
Improving Pregnancy Outcomes With Progesterone
ClinicalTrials.gov study NCT03297216. IPD Sharing: NO. Countries: 1. Publications: 2.
RCT of Progesterone to Prevent Preterm Birth in Nulliparous Women With a Short Cervix
ClinicalTrials.gov study NCT00439374. IPD Sharing: YES. Countries: 1. Publications: 1.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.