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56 results for “prosthetic joint infection”
Evaluation of synovial calprotectin by using a lateral flow stool test for the diagnosis of prosthetic joint infections
<p>The analysis of synovial fluid is a crucial step in the diagnostic process of prosthetic joint infections (PJI) and several studies illustrated the efficacy of synovial calprotectin in supporting the diagnosis of PJI. In this study, synovial calprotectin was analyzed by a commercial stool test to explore whether the detected levels might predict PJIs. The synovial fluids of 55 were analyzed. Calprotectin levels were compared to other synovial biomarkers of PJI. Of the 55 synovial fluids, 13 patients were diagnosed with PJI and 42 with an aseptic failure of the implant. The specificity, sensitivity, and AUC of calprotectin resulted 0.90, 0.85, and 0.86 (95%CI: 0.72-0.99), respectively with a set threshold of 226.5 µg/g. The values of calprotectin had a moderate and statistically relevant correlation with the synovial leucocyte counts (rs = 0.54, p = 0.0003) and percentage of synovial neutrophils (rs = 0.68, p = 0.0000). From this analysis, it can be concluded that synovial calprotectin is a valuable biomarker that correlates with other established indicator of local infection, and the use of a commercial lateral flow stool test could be a cost-effective strategy delivering rapid and reliable results and supporting the diagnostic process of PJI.</p>
Study to Evaluate the Efficacy and Safety of TRL1068 for the Treatment of Prosthetic Joint Infection
ClinicalTrials.gov study NCT06621251. IPD Sharing: NO. Countries: 1. Publications: 1.
Phage Therapy in Prosthetic Joint Infection Due to Staphylococcus Aureus Treated With DAIR.
ClinicalTrials.gov study NCT05369104. IPD Sharing: NO. Countries: 1. Publications: 0.
Study to Evaluate Safety and Activity of TRL1068 in Prosthetic Joint Infections
ClinicalTrials.gov study NCT04763759. IPD Sharing: NO. Countries: 1. Publications: 3.
New Molecular Approaches for Diagnosis of Prosthetic Joint Infection
ClinicalTrials.gov study NCT06670885. IPD Sharing: YES. Countries: 1. Publications: 7.
Use of Collatamp G Antibiotic Impregnated Sponges in the Treatment of Peri-prosthetic Total Joint Infections
ClinicalTrials.gov study NCT01667874. IPD Sharing: NO. Countries: 1. Publications: 1.
The Influence of Antibiotic Prophylaxis on Intraoperative Prosthetic Joint Infection Cultures
ClinicalTrials.gov study NCT02413034. IPD Sharing: NO. Countries: 0. Publications: 4.
Safety and Efficacy of CEM-102 With Rifampin Compared to Standard Therapy in Patients With Prosthetic Joint Infections or Spacer Infection
ClinicalTrials.gov study NCT01756924. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Knee Prosthetic Joint Infection Antibiotic Elution
ClinicalTrials.gov study NCT06023238. IPD Sharing: UNDECIDED. Countries: 1. Publications: 3.
Tedizolid Prolonged Treatment for Prosthetic Joint Infections
ClinicalTrials.gov study NCT03378427. IPD Sharing: NO. Countries: 1. Publications: 17.
Rapid Diagnosis of Prosthetic Joint Infection by Matrix-assisted Laser Desorption
ClinicalTrials.gov study NCT03717090. IPD Sharing: UNDECIDED. Countries: 1. Publications: 6.
Rifampicin Combination Therapy Versus Monotherapy for Staphylococcal Prosthetic Joint Infection
ClinicalTrials.gov study NCT06172010. IPD Sharing: NO. Countries: 1. Publications: 1.
The Effect of Peri-Operative Adjunctive Probiotics on Immunological Markers in Cases of Prosthetic Joint Infection of the Hip and Knee
ClinicalTrials.gov study NCT06919913. IPD Sharing: YES. Countries: 1. Publications: 0.
Antibiogram and Biofilm Formation of Bacteria Causing Prosthetic Joint Infections Isolated From Assiut University Hospital
ClinicalTrials.gov study NCT05239312. IPD Sharing: Not stated. Countries: 0. Publications: 14.
Quality of Life Assessment in Patients Undergoing Prolonged Suppressive Antibiotherapy for Prosthetic Joint Infection.
ClinicalTrials.gov study NCT02805803. IPD Sharing: NO. Countries: 1. Publications: 0.
Bacteriophage Therapy in Patients With Prosthetic Joint Infections
ClinicalTrials.gov study NCT04787250. IPD Sharing: NO. Countries: 1. Publications: 0.
Efficacy and Safety Study of Antibiotic Treatment to Treat Hip Prosthetic Joint Infection
ClinicalTrials.gov study NCT01757236. IPD Sharing: Not stated. Countries: 3. Publications: 0.
Probiotics in the Prevention of Recurrent Prosthetic Joint Infection of the Hip and Knee
ClinicalTrials.gov study NCT06636669. IPD Sharing: NO. Countries: 1. Publications: 0.
PRO-DIAG: Improved Diagnosis of Prosthetic Joint Infections
ClinicalTrials.gov study NCT03444571. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Synovial Aspiration and Serological Testing in Two-stage Revision Arthroplasty of Prosthetic Joint Infection
ClinicalTrials.gov study NCT03038464. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
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