Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
24
datasets available to search
ShareScore release 0.9.0
Dataset results
24 results for “protein interaction modulators”
Amino Acids Modulate Liquid-Liquid Phase Separation in vitro and in vivo by Regulating Protein-Protein Interactions
<p>The metadata, plots and microscopy images for the manuscript "Amino Acids Modulate Liquid-Liquid Phase Separation in vitro and in vivo by Regulating Protein-Protein Interactions".</p>
Data from: Epistatic interaction of the melanocortin 1 receptor and agouti signaling protein genes modulates wool color in the Brazilian Creole sheep
Different pigmentation genes have been associated with color diversity in domestic animal species. The melanocortin 1 receptor (MC1R), agouti signaling protein (ASIP), tyrosinase related protein-1 (TYRP1) and v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT) genes are candidate genes responsible for variation in wool color among breeds of sheep. Although the influence of these genes has been described in some breeds, in many others the effect of interactions among genes underlying wool color has not been investigated. The Brazilian Creole sheep is a local breed with a wide variety of wool color, ranging from black to white with several intermediate hues. We analyzed in this study the influence of the genes MC1R, ASIP, TYRP1 and KIT on the control of wool color in this breed. A total of 410 samples were analyzed, including 148 white and 262 colored individuals. The MC1R and ASIP polymorphisms were significantly associated with the segregation of either white or colored wool. The dominant MC1R allele (ED p.M73K and p.D121N) was present only in colored animals. All white individuals were homozygous for the MC1R recessive allele (E+) and carriers of the duplicated copy of ASIP. A gene expression essay showed that only the carrier of the duplicated copy of ASIP produces increased levels in skin, not detectable in the single homozygous copy. These results demonstrate that the epistatic interaction of the genotypes in the MC1R and ASIP gene is responsible for the striking color variation in the Creole breed.
Data from: Epistatic interaction of the melanocortin 1 receptor and agouti signaling protein genes modulates wool color in the Brazilian Creole sheep
Open the record for dataset details and reuse information.
SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells
GEO Series GSE69594. Mus musculus. 16 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by array.
The insulator protein SU(HW) modulates nuclear lamina interactions of the Drosophila genome: DamID
GEO Series GSE20311. Drosophila melanogaster. 22 samples. Type: Genome binding/occupancy profiling by genome tiling array.
The insulator protein SU(HW) modulates nuclear lamina interactions of the Drosophila genome
GEO Series GSE20313. Drosophila melanogaster. 25 samples. Type: Genome binding/occupancy profiling by genome tiling array; Expression profiling by array.
A lncRNA, SPRIGHTLY, interacts with Polypyrimidine Tract Binding Protein 1 (PTBP1) and modulates SET And MYND Domain Containing 3 (SMYD3) exon skipping.
GEO Series GSE189643. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Plasmodium falciparum MORC protein modulates gene expression through interaction with heterochromatin
GEO Series GSE241313. Plasmodium falciparum. 12 samples. Type: Expression profiling by high throughput sequencing.
Hedgehog-interacting protein orchestrates alveologenesis and protects against BPD and emphysema by modulating hedgehog-IGF1 signaling axis
GEO Series GSE271417. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
The insulator protein SU(HW) modulates nuclear lamina interactions of the Drosophila genome: expression
GEO Series GSE20312. Drosophila melanogaster. 3 samples. Type: Expression profiling by array.
The interaction of influenza A NS1 and cellular TRBP protein modulates the function of RNA interference machinery
GEO Series GSE189776. Mus musculus; Homo sapiens. 5 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Capturing the Hierarchically Assorted Modules of Protein Interaction in the Organized Nucleome
<p>The annotated MS2 spectrums of CBDPS crosslinked peptides derived from soybean nuclei.</p>
Functional module detection through integration of single-cell RNA sequencing data with protein–protein interaction networks
GEO Series GSE133948. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells [array]
GEO Series GSE69593. Mus musculus. 6 samples. Type: Expression profiling by array.
Dual-mode modulation of Smad signaling by Smad-interacting protein Sip1 is required for myelination in the central nervous system
GEO Series GSE40431. Mus musculus; Rattus norvegicus. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by array.
Unraveling the cohesin-chromatin interface: identifying protein interactions that modulate chromosome structure and function [ChIP-Seq]
GEO Series GSE288455. Mus musculus. 22 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells[ChIP-seq]
GEO Series GSE69592. Mus musculus. 10 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Tranposable elements modulate human mRNAs and lncRNAs via specific RNA-protein interactions.
GEO Series GSE61238. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Unraveling the cohesin-chromatin interface: identifying protein interactions that modulate chromosome structure and function [Micro-C]
GEO Series GSE288456. Mus musculus. 2 samples. Type: Other.
G-Quadruplex structural motifs modulate protein-RNA interactions within the transcriptome
GEO Series GSE284272. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.