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15
datasets available to search
ShareScore release 0.9.0
Dataset results
15 results for “protein sorting”
High-throughput discovery of transmembrane helix dimers from human single-pass membrane proteins with TOXGREEN sort-seq
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Data from: Y-box protein 1 is required to sort microRNAs into exosomes in cells and in a cell-free reaction
Exosomes are small vesicles that are secreted from metazoan cells and may convey selected membrane proteins and small RNAs to target cells for the control of cell migration, development and metastasis. To study the mechanisms of RNA packaging into exosomes, we devised a purification scheme based on the membrane marker CD63 to isolate a single exosome species secreted from HEK293T cells. Using immunoisolated CD63-containing exosomes we identified a set of miRNAs that are highly enriched with respect to their cellular levels. To explore the biochemical requirements for exosome biogenesis and RNA packaging, we devised a cell-free reaction that recapitulates the species-selective enclosure of miR-223 in isolated membranes supplemented with cytosol. We found that the RNA-binding protein Y-box protein I (YBX1) binds to and is required for the sorting of miR-223 in the cell-free reaction. Furthermore, YBX1 serves an important role in the secretion of miRNAs in exosomes by HEK293T cells.
Data from: Y-box protein 1 is required to sort microRNAs into exosomes in cells and in a cell-free reaction
Open the record for dataset details and reuse information.
Inhibition of acid or neutral sphingomyelinases differentially impacts RNA and protein cargo sorting to extracellular vesicles
GEO Series GSE254401. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Identification of IL1R2 as a Spermatogonial Stem Cell-specific Sorted Protein in Humans and Mice
GEO Series GSE301767. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Engineering orthogonal signaling pathways reveals the sparse distribtion of protein protein interactions in sequence space [degenerate_library_sort_seq]
GEO Series GSE120780. Escherichia coli str. K-12 substr. MG1655. 56 samples. Type: Other.
RNA-seq of donor matched freshly FACS-sorted Tregs (CD4+CD127loCD25hi) and Tconvs (CD4+CD127hiCD25lo) to compare both the protein-coding and non-coding transcriptomes from three different healthy dono
GEO Series GSE148267. Homo sapiens. 11 samples. Type: Expression profiling by high throughput sequencing.
The impact of Lactobacillus plantarum sortase on target-protein sorting, gastrointestinal persistence and host immunomodulation
GEO Series GSE34999. Lactiplantibacillus plantarum. 8 samples. Type: Expression profiling by array.
Engineering orthogonal signaling pathways reveals the sparse distribtion of protein protein interactions in sequence space [combinatorial_library_sort_seq]
GEO Series GSE120786. Escherichia coli str. K-12 substr. MG1655. 55 samples. Type: Other.
Expression data of ribosomal proteins from sorted hematopoietic stems cells from patients with low risk MDS.
GEO Series GSE30201. Homo sapiens. 19 samples. Type: Expression profiling by array.
Vacuolar protein sorting 33B deficiency effect on conventional dendritic cell type 1 subpopulation
GEO Series GSE184505. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Expression data from iPS cell derived hepatocyte-like cells sorted with antibody against cell surface protein SLC10A1
GEO Series GSE80279. Homo sapiens. 12 samples. Type: Expression profiling by array.
Sorting nexin 10 sustains platelet-derived growth factor receptor signaling in glioblastoma stem cells via endosomal protein sorting
GEO Series GSE221714. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
Effect of depletion of vacuolar protein sorting 13 homolog c (Vps13c) in heart tissue from ventricles of wild-type (WT) and cardiac-specific knockout (Vps13c-cKO) mice.
GEO Series GSE307260. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome study of the deletion of vacuolar protein sorting related vps13 and vps21 in Trichoderma reesei
GEO Series GSE187573. Trichoderma reesei. 9 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.