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37 results for “proteoglycan”
James et al. Short-term exposure to ciprofloxacin reduces proteoglycan loss in tendon explants DATASET
<p>Publicly available dataset for research article titled "<em>Short-term exposure to ciprofloxacin reduces proteoglycan loss in tendon explants</em>"</p>
James et al. Short-term exposure to ciprofloxacin reduces proteoglycan loss in tendon explants DATASET
<p>Dataset associated with results in the article "Short-term exposure to ciprofloxacin reduces proteoglycan loss in tendon explants".</p>
Proteoglycan 4 (lubricin) is a highly sialylated glycoprotein associated with cardiac valve damage in animal models of infective endocarditis
Open the record for dataset details and reuse information.
Assessment of 99mTc-NTP 15-5 Uptake on Cartilage, a New Proteoglycan Tracer
ClinicalTrials.gov study NCT04481230. IPD Sharing: Not stated. Countries: 1. Publications: 2.
The Effect of Exercise on Serum Levels of Collagen and Proteoglycan in Patients With Knee Osteoarthritis (EFEX-OA-01)
ClinicalTrials.gov study NCT04542655. IPD Sharing: NO. Countries: 1. Publications: 1.
Characterization of Proteoglycan Depletion in Femoroacetabular Impingement With T1ρ Magnetic Resonance Imaging (MRI)
ClinicalTrials.gov study NCT01578694. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Syndecan-4 proteoglycan modulates glucose uptake and insulin sensitivity in myoblasts
<p>Skeletal muscle glucose uptake is required for cellular metabolism and normalization of postprandial blood glucose levels. Transmembrane heparan sulfate proteoglycan syndecan-4 (SDC4) is important for muscle regeneration, cell interaction and structure, and it affects whole body metabolism, although the mechanism remains unclear. In this study, we demonstrated that SDC4 knock down increases glucose uptake by mammalian myoblasts (i.e., activated satellite cells). Silencing SDC4 increased the phosphorylation AS160 (Akt substrate of 160 kDa or TBC1D4), an important element of glucose transporter type 4 (GLUT4) translocation, and GLUT4 levels. These changes increased 2–deoxy-2–(<sup>18</sup>F)fluoro-D-glucose uptake by C2C12 myoblasts independent of insulin treatment. Mitochondrial routine respiration, electron transport system, reserve capacity, and oxidative phosphorylation were also increased following SDC4 silencing. SDC4 knockdown cells exhibited a higher GLUT4 density along the plasma membrane compared with behind it. Super-resolution direct stochastic optical reconstruction microscopy (dSTORM) imaging revealed an increased number of skeletons of the actin network following insulin treatment, but not in SDC4-silenced cells. Notably, knocking down SDC4 increased the insulin sensitivity of the cells. Our results suggest that this new mechanism can increase glucose uptake through insulin-independent signal transduction.</p> <p>Proteomics data.</p>
Proteoglycan 4 Mechanism the Effectiveness of Pulmaonry Recovery in COPD Patients
ClinicalTrials.gov study NCT02764658. IPD Sharing: NO. Countries: 0. Publications: 3.
Colorectal Omics and OfCS Proteoglycans
ClinicalTrials.gov study NCT06287671. IPD Sharing: NO. Countries: 1. Publications: 0.
Efficacy and Tolerability of Proteoglycan F in the Treatment of Knee Osteoarthritis
ClinicalTrials.gov study NCT04998825. IPD Sharing: NO. Countries: 1. Publications: 0.
A Proteomic Atlas of Atherosclerosis: The Contribution of Proteoglycans to Sex Differences, Plaque Phenotypes and Outcomes
GEO Series GSE241346. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
VISTA is an activating receptor that binds the proteoglycan Syndecan-2 on monocytes.
GEO Series GSE173747. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing; Other.
Tumor matrix proteoglycan accumulation and processing alters T cell effector function and the response to immunotherapy in oligometastatic colorectal cancer
GEO Series GSE316301. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
The critical role of chondroitin sulfate proteoglycan interactions with receptor PTPσ in the inhibition of neural repair after stroke
GEO Series GSE168934. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Enduring Histone Methylation Changes at Proteoglycan Network Genes following Ethanol Exposure
GEO Series GSE117925. Mus musculus. 18 samples. Type: Expression profiling by array.
Surface proteoglycans expressions in oral squamous cell carcinoma
GEO Series GSE33788. Homo sapiens. 120 samples. Type: Expression profiling by RT-PCR.
Hyaluronan And Proteoglycan Link Protein 1 (HAPLN1) promotes Proliferation and Pro-inflammatory phenotype but not mobility of Fibroblast-like Synoviocytes
GEO Series GSE200597. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
Colorectal Omics and ofCS Proteoglycans (COCO) in Screening and a Diagnostic Pathway
ClinicalTrials.gov study NCT07237984. IPD Sharing: YES. Countries: 1. Publications: 0.
Safety of Antithrombotic Heparin Proteoglycan Mimetic APAC in Peripheral Arterial Occlusive Disease and Chronic Limb-threatening Ischemia
ClinicalTrials.gov study NCT07352800. IPD Sharing: NO. Countries: 1. Publications: 0.
A PHASE II PROSPECTIVE RANDOMIZED DOUBLE-MASKED CROSSOVER STUDY ASSESSING THE SAFETY & EFFICACY OF RHPRG4 (450 μG/ML RECOMBINANT HUMAN PROTEOGLYCAN 4) COMPARED TO VEHICLE FOR THE TREATMENT OF OCULAR G
ClinicalTrials.gov study NCT07118254. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.