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38 results for “quality of evidence”

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dryad40/100

What drives poor quality of care for child diarrhea? Experimental evidence from India

<p>Most healthcare providers in developing countries know that oral rehydration salts (ORS) is a lifesaving treatment for child diarrhea, yet few prescribe it. This know-do gap has puzzled experts for decades and has cost millions of lives. Using several randomized controlled trials among private providers in 253 towns in India, we estimated the extent to which ORS under-prescription is driven by financial incentives to sell more lucrative medicines, stock-outs of ORS, and provider perceptions that patients do not want ORS. We found that patients expressing a preference for ORS increased ORS prescribing by 27 percentage points. Eliminating stock-outs increased ORS provision by 6.8 percentage points. Eliminating financial incentives to sell medicines had no effect on average but increased ORS prescribing at pharmacies by 9 percentage points. Our findings, combined with patient exit surveys suggest that provider perceptions that patients do not want ORS explain 42% of under-prescribing, while stock-outs and financial incentives explain only 6% and 5% respectively.</p>

opencc-zeroJan 2024View details →
zenodo40/100

The need to develop tailored tools for improving the quality of thematic bibliometric analyses: Evidence from papers published in Sustainability and Scientometrics (Dataset)

<p>This dataset contains the data used to completed the article&nbsp;under peer review:</p> <p>References:<br> Cabezas, A.; Milan&eacute;s, Y.;Alba, R.; Delgado, A.M. (2023). The need to develop tailored tools for improving the quality of thematic bibliometric analyses: Evidence from papers published in Sustainability and Scientometrics. (Article&nbsp;under peer review)</p> <p>Institutions: Spain (Universidad Internacional de La Rioja, Universidad Pablo de Olavide, Hospital Universitario Virgen de las Nieves)</p>

opencc-by-4.0Jul 2023View details →
dryad40/100

What drives poor quality of care for child diarrhea? Experimental evidence from India

Open the record for dataset details and reuse information.

publicJan 2024View details →
ClinicalTrials.gov36/100

Evaluating Evidence-Based Quality Improvement of Comprehensive Women's Health Care Implementation in Low-Performing VAs

ClinicalTrials.gov study NCT03238417. IPD Sharing: NO. Countries: 1. Publications: 1.

closedIPD-NOFeb 2026View details →
ClinicalTrials.gov36/100

Community-Based Exercise Oncology: Real-World Evidence of High Adherence, Improved Quality of Life and Cost-Effectiveness Across the Cancer Continuum

ClinicalTrials.gov study NCT07368192. IPD Sharing: NO. Countries: 1. Publications: 1.

closedIPD-NOFeb 2026View details →
dryad36/100

Data and code for: Decline in offspring quantity but not quality from successive matings in male rainforest <em>Drosophila</em>, with no evidence for genetic divergence in male mating behaviour along climatic and density gradients

Open the record for dataset details and reuse information.

publicNov 2025View details →
dryad32/100

Data from: Quality of evidence considered by Health Canada in granting full market authorization to new drugs with a conditional approval: a retrospective cohort study

Objectives: This study examines the characteristics of studies that Health Canada uses to grant full marketing authorization for products given a conditional approval between January 1, 1998 and June 30, 2017. Design: Cohort study. Data sources: Journal articles listing drugs that fulfilled their conditions and received full marketing authorization, Notice of Compliance database, Notice of Compliance with conditions web site, Qualifying Notices listing required confirmatory studies, clinicaltrials.gov, PubMed, Embase, companies making products being analyzed, journal articles resulting from confirmatory studies. Interventions: None Primary and secondary outcome measures: Characteristics of studies - study design (randomized controlled trials, observational), primary outcome used (clinical, surrogate), blinding, number of patients in studies, patient median age, number of men and women. Results: Eleven companies confirmed 36 publications for 19 products (21 indications). Twenty-nine out of the 36 studies were randomized controlled trials (RCTs) but only 10 stated if they were blinded. Twenty used surrogate outcomes. The median age of patients was 56 (interquartile range (IQR) 44, 61). The median number of men per study/trial was 184 (IQR 58, 514) versus women - 141 (IQR 46, 263). Conclusions: Postmarket studies required by Health Canada had more rigorous methodology than those required by either the Food and Drug Administration or the European Medicines Agency. There were still deficiencies in these studies. The absence of blinding in the majority of RCTs may introduce bias in their results. The use of surrogate outcomes especially in oncology trials means that improvements in survival are not available. The relatively young age of patients, even for products for cancer, means that predicting how the elderly will respond is often unknown. The almost universal finding that men outnumbered number women may make it hard to differentiate responses by sex. These results raise potential concerns about the quality of evidence that Health Canada accepts.

opencc-zeroDec 2017View details →
zenodo32/100

An evidence map of research assessing the effects of timber harvesting on water quality, biotic and biodiversity indicators in running waters: Data and R code

<p>These are the data and R code that accompany the Forest Ecology and Management publication titled "An evidence map of research assessing the effects of timber harvesting on water quality, biotic and biodiversity indicators in running waters".&nbsp;</p>

opencc-by-4.0Dec 2024View details →
ClinicalTrials.gov32/100

Effect of Implementing Evidence-based Practice and Nurse's Behavior Change on Quality of Care in Intensive Care Unit: Focus on Ventilator Associated Pneumonia in a Tertiary Hospital in Bangladesh

ClinicalTrials.gov study NCT06624540. IPD Sharing: NO. Countries: 2. Publications: 1.

closedIPD-NOFeb 2026View details →
ClinicalTrials.gov32/100

Intervention to Bridge the Evidence-based Gap in Stroke Care Quality

ClinicalTrials.gov study NCT02212912. IPD Sharing: Not stated. Countries: 1. Publications: 3.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov32/100

A Cluster Randomized Trial to Assess the Impact of Opinion Leader Endorsed Evidence Summaries on Improving Quality of Prescribing for Patients With Chronic Cardiovascular Disease

ClinicalTrials.gov study NCT00175279. IPD Sharing: Not stated. Countries: 1. Publications: 2.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov32/100

Implementing Guidelines for Smoking Cessation: A Randomized Trial of Evidence-Based Quality Improvement

ClinicalTrials.gov study NCT00012987. IPD Sharing: Not stated. Countries: 1. Publications: 10.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov32/100

Reduction of Infection in Neonatal Intensive Care Units Using the Evidence-based Practice for Improving Quality

ClinicalTrials.gov study NCT02600195. IPD Sharing: Not stated. Countries: 1. Publications: 8.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov32/100

Evidence Based QUality Improvement for Prescribing Stewardship in ICU (EQUIPS-ICU)

ClinicalTrials.gov study NCT06666738. IPD Sharing: YES. Countries: 0. Publications: 1.

controlledIPD-YESFeb 2026View details →
ClinicalTrials.gov32/100

High Quality Evidence of Chinese Lupus Nephritis (HELP)

ClinicalTrials.gov study NCT03001973. IPD Sharing: YES. Countries: 1. Publications: 2.

controlledIPD-YESFeb 2026View details →
ClinicalTrials.gov32/100

IDOMENEO - Is Treatment Reality in Vascular Medicine Evidence-based and Follows Guideline Recommendations? A Project for Quality Development Exemplified by Peripheral Arterial Disease (PAD)

ClinicalTrials.gov study NCT03098290. IPD Sharing: UNDECIDED. Countries: 1. Publications: 16.

restrictedIPD-UNDECIDEDFeb 2026View details →
dryad32/100

Data from: Quality of evidence considered by Health Canada in granting full market authorization to new drugs with a conditional approval: a retrospective cohort study

Open the record for dataset details and reuse information.

publicApr 2018View details →
dryad28/100

Data from: No evidence of positive assortative mating for genetic quality in fruit flies

In sexual populations the effectiveness of selection will depend on how gametes combine with respect to genetic quality. If gametes with deleterious alleles are likely to combine with one another, deleterious genetic variation can be more easily purged by selection. Assortative mating, where there is a positive correlation between parents in a phenotype of interest such as body size, is often observed in nature, but does not necessarily reveal how gametes ultimately combine with respect to genetic quality itself. We manipulated genetic quality in fruit fly populations using an inbreeding scheme designed to provide an unbiased measure of mating patterns. While inbred flies had substantially reduced reproductive success, their gametes did not combine with those of other inbred flies more often than expected by chance, indicating a lack of positive assortative mating. Instead, we detected a negative correlation in genetic quality between parents, i.e., disassortative mating, which diminished with age. This pattern is expected to reduce the genetic variance for fitness, diminishing the effectiveness of selection. We discuss how mechanisms of sexual selection could produce a pattern of disassortative mating. Our study highlights that sexual selection has the potential to either increase or decrease genetic load.

opencc-zeroSep 2019View details →
dryad28/100

Data from: A critical evaluation of the volume, relevance and quality of evidence submitted by the tobacco industry to oppose standardised packaging of tobacco products

Objectives: To examine the volume, relevance and quality of transnational tobacco corporations' (TTCs) evidence that standardised packaging of tobacco products 'won't work', following the UK government's decision to 'wait and see' until further evidence is available. Design Content analysis. Setting: We analysed the evidence cited in submissions by the UK's four largest TTCs to the UK Department of Health consultation on standardised packaging in 2012. Outcome measures: The volume, relevance (subject matter) and quality (as measured by independence from industry and peer-review) of evidence cited by TTCs was compared with evidence from a systematic review of standardised packaging . Fisher's exact test was used to assess differences in the quality of TTC and systematic review evidence. 100% of the data were second-coded to validate the findings: 94.7% intercoder reliability; all differences were resolved. Results: 77/143 pieces of TTC-cited evidence were used to promote their claim that standardised packaging 'won't work'. Of these, just 17/77 addressed standardised packaging: 14 were industry connected and none were published in peer-reviewed journals. Comparison of TTC and systematic review evidence on standardised packaging showed that the industry evidence was of significantly lower quality in terms of tobacco industry connections and peer-review (p&lt;0.0001). The most relevant TTC evidence (on standardised packaging or packaging generally, n=26) was of significantly lower quality (p&lt;0.0001) than the least relevant (on other topics, n=51). Across the dataset, TTC-connected evidence was significantly less likely to be published in a peer-reviewed journal (p=0.0045). Conclusions: With few exceptions, evidence cited by TTCs to promote their claim that standardised packaging 'won't work' lacks either policy relevance or key indicators of quality. Policymakers could use these three criteria—subject matter, independence and peer-review status—to critically assess evidence submitted to them by corporate interests via Better Regulation processes.

opencc-zeroDec 2013View details →
zenodo28/100

Quality of Evidence submitted to NICE Technology Appraisals (2000-2020)

<p>This file&nbsp;provides a data set on 409 Technology Appraisals (TAs) issued by NICE between March 2000 when TA1 was published and September 11, 2019 when TA 600 was published.&nbsp;For each of these TAs, there are analyses including a score for their Data Quality, QoL Data Quality, Quality of Submitted Evidence, Overall Quality of Evidence for decision, and Quality of Submitted RCTs. A legend is in the file&#39;s second tab.</p>

opencc-by-4.0Aug 2021View details →

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Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record