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248 results for “quiescence”
Changes in gene expression during germination reveal pea genotypes with either 'quiescence' or 'escape' mechanisms of waterlogging tolerance
<p>Waterlogging causes germination failure in pea (<em>Pisum sativum</em> L.). Three genotypes (BM-3, NL-2 and Kaspa) contrasting in ability to germinate in waterlogged soil were exposed to different durations of waterlogging. Whole genome RNAseq was employed to capture differentially expressing genes. The ability to germinate in waterlogged soil was associated with testa colour and testa membrane integrity as confirmed by electrical conductivity measurements. Among the most differentially regulated genes, upregulated gene tyrosine protein kinase responsible for metabolic regulation and downregulated LOX5 involved in fat metabolism indicated energy preservation in tolerant Kaspa, while in the other tolerant NL-2 subtilase family protein and PNC2 involved in protein and fat metabolism respectively showed upregulated expression suggesting energy utilization during waterlogging. By contrast, in sensitive genotype BM-3 high upregulation was recorded for the kunitz-type trypsin/protease inhibitor whose role is blocking the activity of protein metabolism leading to excessive lipid metabolism causing membrane leakage and subsequent seed damage. Pathway analyses based on gene ontologies showed seed storage protein metabolism as upregulated in tolerant genotypes and downregulated in the sensitive genotype. Understanding the tolerance mechanism provides a platform to breed for adaptation to waterlogging stress at germination in pea. </p>
Changes in gene expression during germination reveal pea genotypes with either 'quiescence' or 'escape' mechanisms of waterlogging tolerance
<p>Waterlogging causes germination failure in pea (<em>Pisum sativum</em> L.). Three genotypes (BM-3, NL-2 and Kaspa) contrasting in ability to germinate in waterlogged soil were exposed to different durations of waterlogging. Whole genome RNAseq was employed to capture differentially expressing genes. The ability to germinate in waterlogged soil was associated with testa colour and testa membrane integrity as confirmed by electrical conductivity measurements. Among the most differentially regulated genes, upregulated gene tyrosine protein kinase responsible for metabolic regulation and downregulated LOX5 involved in fat metabolism indicated energy preservation in tolerant Kaspa, while in the other tolerant NL-2 subtilase family protein and PNC2 involved in protein and fat metabolism respectively showed upregulated expression suggesting energy utilization during waterlogging. By contrast, in sensitive genotype BM-3 high upregulation was recorded for the kunitz-type trypsin/protease inhibitor whose role is blocking the activity of protein metabolism leading to excessive lipid metabolism causing membrane leakage and subsequent seed damage. Pathway analyses based on gene ontologies showed seed storage protein metabolism as upregulated in tolerant genotypes and downregulated in the sensitive genotype. Understanding the tolerance mechanism provides a platform to breed for adaptation to waterlogging stress at germination in pea. </p>
Inducing Immune Quiescence to Prevent HIV Infection in Women
ClinicalTrials.gov study NCT02079077. IPD Sharing: Not stated. Countries: 1. Publications: 2.
XMM spectra of eruptions and quiescence used in the paper titled "Alive and Strongly Kicking: Stable X-ray Quasi-Periodic Eruptions from eRO-QPE2 over 3.5 Years"
<p>The gz file has a folder containing 10 sets of spectra (two per XMMID: one using data from eruptions and one from quiescence). Each one has a corresponding rmf, arf and a background file.</p> <p>The files of the format: <span>PN_Grouped_spectrumXX...fits are xspec ready. They are grouped with specgroup task of XMMSAS with mincounts=1 oversample=3. Thus, cstat is recommended while fitting in XSPEC.</span></p> <p><span>Alternatively, the original source spectra (</span><span>PN_SPEC_SRCBKGXXX...fits) are also available so that the user can bin them as per their requirement.</span></p> <p><span>The background spectra have the following naming sequence: </span><span>PN_SPEC_BKGXX</span></p> <p> </p> <p><span>XX = "hi" ==> eruption spectra</span></p> <p><span>XX = "low" ==> quiescence spectra</span></p> <p><span>The numbers 1...5 correspond to XMM obsIDs as follows:</span></p> <p><span>1: </span><span>0872390101</span></p> <p><span>2: 0883770201</span></p> <p><span>3: 0893810501</span></p> <p><span>4: 0932590101</span></p> <p><span>5: 0932590201</span></p> <p> </p>
Dataset pHluorin cells experiencing entry into quiescence
<p>Dataset relative to <a href="https://www.biorxiv.org/content/10.1101/2020.11.25.395608v2">https://www.biorxiv.org/content/10.1101/2020.11.25.395608v2</a></p> <p><strong>Data type</strong>: 2D microscopy images(.tif)</p> <p><strong>Microscopy data type</strong>: Brightfield images + 2 colors</p> <p><strong>Imaging</strong>: 60x 1.40 NA brightfield, 6.0µm*6.0µm sCMOS</p> <p><strong>Cell type</strong>: Budding yeast cells (BY4742) + pHluorin</p> <p><strong>File format</strong>: .tif (16-bit RGB, 1 color per z-stack). Each folder is a channel</p> <p><strong>Image size</strong>: 2000x2000 pixels, binned to 2x2</p> <p><strong>Author(s)</strong>: Théo, ASPERT; Basile, JACQUEL; Gilles CHARVIN</p> <p><strong>Contact email</strong>: theo.aspert@gmail.com; charvin@igbmc.fr</p> <p><strong>Affiliation</strong>: IGBMC, Université de Strasbourg</p> <p><strong>Funding bodies</strong>: This work was supported by the Agence Nationale pour la Recherche, the grant ANR-10-LABX-0030-INRT, a French State fund managed by the Agence Nationale de la Recherche under the frame program Investissements d'Avenir ANR-10-IDEX-0002-02.</p> <p> </p> <p><strong>Additional information: </strong>Framerate is indicated in the .rtf file.</p>
Quiescence Enables Unrestricted Cell Fate in Naive Embryonic Stem Cells
GEO Series GSE210915. Mus musculus. 42 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
The transition from proliferation to quiescence in glioblastoma stem-like cells requires Ca2+ signaling and mitochondria remodeling
GEO Series GSE93991. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
The histone lysine acetyltransferase HBO1 (KAT7) regulates hematopoietic stem cell quiescence and self-renewal
GEO Series GSE185959. Mus musculus. 32 samples. Type: Expression profiling by high throughput sequencing.
Cathepsin W restrains peripheral regulatory T cells for mucosal immune quiescence
GEO Series GSE225785. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Setd2 regulates quiescence and differentiation of adult hematopoietic stem cells by restricting RNA polymerase II elongation
GEO Series GSE112550. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Investigations into the basal neural-like properties of dental pulp stem cells reveals they possess a functional type 2 muscarinic receptor which regulates quiescence
GEO Series GSE297021. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
H2AK119ub dynamics controls hair follicle stem cell quiescence [RNA-Seq 1]
GEO Series GSE279012. Mus musculus. 5 samples. Type: Expression profiling by high throughput sequencing.
Cellular responses to long-term phosphate starvation of fission yeast: Maf1 determines fate choice between quiescence and death associated with aberrant tRNA biogenesis
GEO Series GSE213459. Schizosaccharomyces pombe. 14 samples. Type: Expression profiling by high throughput sequencing.
Gene expression in human bone marrow Mesenchymal Stem cell line (hMSC-TERTs) during proliferation, quiescence (G0-arrest) and re-activation.
GEO Series GSE60608. Homo sapiens. 15 samples. Type: Expression profiling by array.
mRNA destabilization by BTG1 and BTG2 maintains T cell quiescence [mTAIL-seq]
GEO Series GSE125889. Mus musculus. 6 samples. Type: Other.
IL-4-induced quiescence of resting naïve B cells is disrupted in systemic lupus erythematosus
GEO Series GSE136035. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
Fibroblast starvation activates ECM remodeling gene transcription and putative enhancers despite inducing quiescence [bruseq]
GEO Series GSE272506. Homo sapiens. 6 samples. Type: Other.
Mecp2 fine-tunes quiescence exit by targeting nuclear receptors
GEO Series GSE227728. Mus musculus. 19 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Staufen1 inhibits MyoD translation to actively maintain muscle stem cell quiescence
GEO Series GSE103603. Mus musculus. 5 samples. Type: Other.
Eurycomalactone switches hepatocellular carcinoma cells into a quiescence state through 5'tRFAla&5'tiRNAAla/DVL/β-catenin pathway inhibition
GEO Series GSE236560. Homo sapiens. 4 samples. Type: Non-coding RNA profiling by array.
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