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Figure 4 in Perinatal exposure to a high-fat diet alters proopiomelanocortin, neuropeptide Y and dopaminergic receptors gene expression and the food preference in offspring adult rats

Figure 4. Body weight on the 120th offspring from mothers submitted the control diet or the high-fat diet. Values are presented as mean ± SEM using two-way ANOVA followed by the Bonferroni multiple-comparison test. *p<0,05; **p<0,005.

Figure 3 in Perinatal exposure to a high-fat diet alters proopiomelanocortin, neuropeptide Y and dopaminergic receptors gene expression and the food preference in offspring adult rats

Figure 3. Body weight on the second day life's of offspring from mothers submitted the control diet (C) or the high-fat diet (H). Values are presented as mean + SEM using Student t-test. C: n = 23; H: n = 23.

Figure 2 in Perinatal exposure to a high-fat diet alters proopiomelanocortin, neuropeptide Y and dopaminergic receptors gene expression and the food preference in offspring adult rats

Figure 2. Pomc (A) and npy (B) gene expression in the hypothalamus of offspring exposed or not to a control diet or high-fat diet during perinatal and/or postnatal period. Values are presented as mean ± SEM using two-way ANOVA followed by the Bonferroni multiplecomparison test. Level of significance: *p<0,05; "a": compared to CC, "b": compared to CH; "c": compared to HC; "d": compared to HH.

Figure 1. Drd1 in Perinatal exposure to a high-fat diet alters proopiomelanocortin, neuropeptide Y and dopaminergic receptors gene expression and the food preference in offspring adult rats

Figure 1. Drd1 (A) and drd2 (B) gene expression in the nucleus accumbens of offspring exposed or not to a control diet or high-fat diet during perinatal and/or postnatal period. Values are presented as mean ± SEM using two-way ANOVA followed by the Bonferroni multiplecomparison test. Level of significance: *p<0,05; "a": compared to CC, "b": compared to CH; "c": compared to HC; "d": compared to HH.

opencc-by-4.0May 2020View details →

zenodo36/100

Results "Anti-obesity effects of individual or combination treatment with Spirulina platensis and green coffee bean aqueous extracts in high-fat diet-induced obese rats"

Background: Obesity, a chronic disease, is associated with serious health risks, including premature mortality. This study aimed to investigate the anti-obesity effects of individual or combination treatment with Spirulina platensis and green coffee bean aqueous extracts in high-fat diet-induced (HFD) obese rats. Methods: Rats were fed on HFD to induce obesity. Corn oil in the HFD accounted for 50.98 % of the calories. Fifty rats were divided into the following five groups (10 rats/group): control, HFD, HFD-Spirulina, HFD-coffee, HFD-Spirulina and coffee co-treatment groups. The serum levels of lipid, leptin, and insulin, as well as the hepatic mRNA levels of fatty acid synthase (FAS), peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1α), and peroxisome proliferator-activated alpha receptor (PPARα) were estimated. Results: The Spirulina and/or green coffee bean aqueous extracts decreased the final bodyweight and liver weight, and the serum levels of alanine aminotransferase, aspartate aminotransferase, and alkaline phosphatase. Additionally, the extracts decreased the serum levels of total cholesterol, triacylglycerol, low-density lipoprotein-cholesterol, leptin, and glucose, and enhanced the serum insulin level. Furthermore, the extracts enhanced the PGC-1α and PPARα mRNA levels and decreased the FAS mRNA levels. Conclusion: The individual or combination treatment with Spirulina and green coffee bean extracts decreased obesity-induced hyperlipidemia. Thus, Spirulina platensis and green coffee can be potentially used to treat obesity.

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Table 2 in Perinatal exposure to a high-fat diet alters proopiomelanocortin, neuropeptide Y and dopaminergic receptors gene expression and the food preference in offspring adult rats

Table 2. Relative food intake of the high-fat diet and control diet during the food preference study in offspring exposed or not a control diet or high-fat diet during perinatal and/or postnatal period.<table><tbody><tr><th></th><th>High-fat diet (g/100 g body weight)</th><th></th></tr></tbody><tbody><tr><th></th><td>102º day</td><td>110º day</td><td>116º day</td></tr><tr><th>CC</th><td>12.6 ± 0.6</td><td>11.3 ± 0.2</td><td>11.1 ± 0.7</td></tr><tr><th>CH</th><td>12.8 ± 0.6</td><td>12.4 ± 0.3</td><td>11.4 ± 0.4</td></tr><tr><th>HC</th><td>16.7 ± 1.1 a.b*</td><td>13.7 ± 0.9</td><td>10.0 ± 0.5</td></tr><tr><th>HH</th><td>15.3 ± 0.7 a.b*</td><td>11.7 ± 0.9</td><td>10.7 ± 0.5</td></tr><tr><th></th><td>Control diet (g/100 g body weight)</td><td></td></tr><tr><th></th><td>102º day</td><td>110º day</td><td>116º day</td></tr><tr><th>CC</th><td>1.4 ± 0.2</td><td>1.1 ± 0.1</td><td>1.1 ± 0.3</td></tr><tr><th>CH</th><td>2.1 ± 0.2</td><td>1.5 ± 0.3</td><td>0.9 ± 0.1</td></tr><tr><th>HC</th><td>1.8 ± 0.2</td><td>1.0 ± 0.3</td><td>1.0 ± 0.3</td></tr><tr><th>HH</th><td>1.9 ± 0.2</td><td>1.1 ± 0.2</td><td>0.7 ± 0.1</td></tr></tbody></table>Values are presented as mean + SEM using two-way ANOVA followed by the Bonferroni multiple-comparison test. *p<0,005; “a”: compared to CC, “b”: compared to CH; “c”: compared to HC; “d”: compared to HH.

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Table 1 in Perinatal exposure to a high-fat diet alters proopiomelanocortin, neuropeptide Y and dopaminergic receptors gene expression and the food preference in offspring adult rats

Table 1. Experimental design. The rats were fed commercial standard diet for rodents control diet or high-fat diet during pregnancy, lactation and post-weaning (up to 100 days of life).During the feeding period, rats consumed both diets (control diet and high-fat diet). The numbers in parentheses indicate the animals number in each nutritional group.<table><tbody><tr><th>Experimental Design</th></tr></tbody><tbody><tr><th>Genitors (n)</th><td>Gestation and lactation</td><td>Offspring during lactation (n)</td><td>Offspring (n)</td><td>Post-weaning (21-100° life’s day)</td><td>Food preference (102-116º life’s day)</td></tr><tr><th></th><td></td><td></td><td>CC (12)</td><td>Control diet</td><td>Control diet</td></tr><tr><th></th><td></td><td></td><td></td><td></td><td>High-fat diet</td></tr><tr><th>GC (5)</th><td>Control diet</td><td>C (23)</td><td>CH (11)</td><td>High-fat diet</td><td>Control diet</td></tr><tr><th></th><td></td><td></td><td></td><td></td><td>High-fat diet</td></tr><tr><th></th><td></td><td></td><td>HC (11)</td><td>Control diet</td><td>Control diet</td></tr><tr><th></th><td></td><td></td><td></td><td></td><td>High-fat diet</td></tr><tr><th>GH (5)</th><td>High-fat diet</td><td>H (23)</td><td>HH (12)</td><td>High-fat diet</td><td>Control diet</td></tr><tr><th></th><td></td><td></td><td></td><td></td><td>High-fat diet</td></tr></tbody></table>

publicMay 2025View details →

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Gut alterations in a chronic kidney disease rat model with diet-induced vascular calcification

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Therapeutic Potential of Nigella sativa Extract against Inflammatory Markers Interleukin-1ß (IL-1ß) and Tumor Necrosis Factor-α (TNF-α) in Rat Models with High Fat Diet

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opencc-by-4.0Nov 2024View details →

zenodo32/100

Lophuromys medicaudatus, L. woosnami, and L. luteogaster are in subgenus Kivumys and woosnami species group. Monotypic. Distribution. Endemic to the Albertine Rift, occurring around Lake Kivu in E DR Congo and Rwanda and SW Uganda (Bwindi). Descriptive notes. Head—body 92-112 mm, tail 73-95 mm, ear 15-19 mm, hindfoot 18-23 mm; weight 29-43 g. Similar to other species in subgenus Kivumys, the Western Rift Brush-furred Rat has unspeckled pelage, and tail ¢.85% of head-body length. Dorsum is uniform dark brown-olive, and venter is orange. Females have three pairs of mammae. Habitat. Mountain swamps and mountain forests at elevations of 1850-2500 m. Food and Feeding. The Western Rift Brush-furred Rat is omnivorous; diets contain 30-100% arthropods, mollusks, seeds, and fruits. Breeding. Female Western Rift Brush-furred Rats can have 1-2 embryos. Pregnant females were observed in February, April, and July. Activity patterns. The Western Rift Brush-furred Rat is terrestrial. Movements, Home range and Social organization. No information. Status and Conservation. Classified as Vulnerable on The IUCN Red List. The Western Rift Brush-furred Rat has never been found in modified secondary environment and is quite rare. Bibliography. Dieterlen (1976b, 1987 2013g), Kasangaki et al. (2003), Verheyen et al. (1996). in Muridae

Lophuromys medicaudatus, L. woosnami, and L. luteogaster are in subgenus Kivumys and woosnami species group. Monotypic. Distribution. Endemic to the Albertine Rift, occurring around Lake Kivu in E DR Congo and Rwanda and SW Uganda (Bwindi). Descriptive notes. Head—body 92-112 mm, tail 73-95 mm, ear 15-19 mm, hindfoot 18-23 mm; weight 29-43 g. Similar to other species in subgenus Kivumys, the Western Rift Brush-furred Rat has unspeckled pelage, and tail ¢.85% of head-body length. Dorsum is uniform dark brown-olive, and venter is orange. Females have three pairs of mammae. Habitat. Mountain swamps and mountain forests at elevations of 1850-2500 m. Food and Feeding. The Western Rift Brush-furred Rat is omnivorous; diets contain 30-100% arthropods, mollusks, seeds, and fruits. Breeding. Female Western Rift Brush-furred Rats can have 1-2 embryos. Pregnant females were observed in February, April, and July. Activity patterns. The Western Rift Brush-furred Rat is terrestrial. Movements, Home range and Social organization. No information. Status and Conservation. Classified as Vulnerable on The IUCN Red List. The Western Rift Brush-furred Rat has never been found in modified secondary environment and is quite rare. Bibliography. Dieterlen (1976b, 1987 2013g), Kasangaki et al. (2003), Verheyen et al. (1996).

opennotspecifiedNov 2017View details →

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Figure 1 in Diet of the black rat (Rattus rattus) in a Canary laurel forest: species identification based on morphological markers and DNA sequences

Figure 1. (a) Map of the Canary Islands showing the location of La Palma Island Biosphere Reserve. (b) Current distribution of the laurel forest (grey) on the island and the study area in Bosque de Los Tilos. (c) Percentages of invertebrates and plants consumed, as detected after the barcode analysis. Each circle represents one location (including one or more separate microsites c. 200 m apart), located in the three plant formations (dominant laurel forest, Morella faya – Erica arborea woodland and fern patch).

opennotspecifiedJul 2021View details →

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Data from: Using molecular diet analysis to inform invasive species management: a case study of introduced rats consuming endemic New Zealand frogs

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publicMay 2019View details →

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Data from: Changes in the diet and body size of a small herbivorous mammal (Sigmodon hispidus, hispid cotton rat) following the Late Pleistocene megafauna extinction

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publicMar 2020View details →

Figure 1 from: Pradana AT, Ritthidej GC, Limprasutr V, Wongtayan A, Lipipun V, Iksen (2024) Antihypertensive activity of spray-dried nanoemulsion containing Asiatic acid-Palm oil in high salt diet-fed rats. Pharmacia 71: 1-10. https://doi.org/10.3897/pharmacia.71.e115091

Figure 1 Antihypertensive activity study in rats: Study timeline (A), Oral administration (B), Non-invasive blood pressure instrument (C), Animal handling on indirect blood pressure test (D).

Figure 7 from: Pradana AT, Ritthidej GC, Limprasutr V, Wongtayan A, Lipipun V, Iksen (2024) Antihypertensive activity of spray-dried nanoemulsion containing Asiatic acid-Palm oil in high salt diet-fed rats. Pharmacia 71: 1-10. https://doi.org/10.3897/pharmacia.71.e115091

Figure 7 In-vivo antihypertensive activity of SD rats (n = 6-8/group); Systolic blood pressure result of 10 weeks induction and 3 weeks treatment period (A), and ACE1 activity post-treatment in serum result (B); Showed statistically different (p < 0.05) for *between non-hypertensive group with all groups, #between treatment group with matrix groups, $between matrix group with non-hypertensive groups, &between captopril and AA nanoparticles groups with AA group.

Figure 5 from: Pradana AT, Ritthidej GC, Limprasutr V, Wongtayan A, Lipipun V, Iksen (2024) Antihypertensive activity of spray-dried nanoemulsion containing Asiatic acid-Palm oil in high salt diet-fed rats. Pharmacia 71: 1-10. https://doi.org/10.3897/pharmacia.71.e115091

Figure 5 Viability of Caco-2 cells (A) and the IC50 value (B) with matrix, Asiatic acid, and Asiatic acid nanoparticles.

Figure 4 from: Pradana AT, Ritthidej GC, Limprasutr V, Wongtayan A, Lipipun V, Iksen (2024) Antihypertensive activity of spray-dried nanoemulsion containing Asiatic acid-Palm oil in high salt diet-fed rats. Pharmacia 71: 1-10. https://doi.org/10.3897/pharmacia.71.e115091

Figure 4 Particle size and distribution with dry method determination (A); *showed statistical difference with p < 0.05; and wet method determination of particle size (B), particle distribution (C), and z-potential (D).