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12 results for “reproductive modification”

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ClinicalTrials.gov36/100

Improving Reproductive Fitness Through Pretreatment With Lifestyle Modification in Obese Women With Unexplained Infertility

ClinicalTrials.gov study NCT02432209. IPD Sharing: YES. Countries: 1. Publications: 2.

controlledIPD-YESFeb 2026View details →
dryad32/100

Data from: Modification of reproductive schedule in response to pathogen exposure in a wild insect: support for the terminal investment hypothesis

<p>Trade-offs in the time and energy allocated to different functions, such as reproductive activities, can be driven by alterations in condition which reduce resources, often in response to extrinsic factors such as pathogens or parasites. When individuals are challenged by a pathogen they may either reduce reproduction as a cost of increasing defence mechanisms, or alternatively, modify reproductive activities so as to increase fecundity thereby minimizing the fitness costs of earlier death, a behaviour consistent with the terminal investment hypothesis (TIH). The TIH predicts that individuals with decreased likelihood of future reproduction will maximize current reproductive effort, which may include shifts in reproductive timing. We examined how wild, adult female click beetles <i>(Agriotes obscurus) </i>responded after exposure to the fungal pathogen<i>Metarhizium brunneum</i>. Field-collected beetles exposed to a high concentration of <i>M. brunneum </i>died earlier and in greater numbers than those exposed to a low concentration. Using a multi-variate approach we examined the impact of pathogen challenge on lifespan and a suite of reproductive traits. Stepdown regression analysis showed that only female lifespan differed among the fungal treatments. Fungal-induced reductions in lifespan drove changes in the reproductive schedule, characterized by a decrease in preoviposition period. Moving the start of egg laying forward allowed the females to offset the costs of a shortened lifespan. These changes suggest that there is a threshold for terminal investment which is dependent on strength of the survival threat. From an applied perspective, our findings imply that exposing adult click beetles to <i>M. brunneum </i>to reduce their population densitymight not succeed and is an approach that needs further investigation.</p>

opencc-zeroAug 2020View details →
zenodo32/100

Se reproduire dans des climats changeants : déterminants et conséquences des modifications de la phénologie de la reproduction chez un reptile vivipare

<p><span>Les modifications des conditions thermiques diurnes et nocturnes induites par le changement climatique peuvent affecter les organismes par une perturbation des processus physiologiques, des traits fonctionnels, des strat&eacute;gies de reproduction et des traits d'histoire de la vie. Les changements ph&eacute;nologiques constituent l&rsquo;une des principales r&eacute;ponses au changement climatique chez de nombreux organismes et ont des cons&eacute;quences majeures sur le succ&egrave;s reproductif des individus. Chez les ectothermes, les changements des dates de reproduction sont particuli&egrave;rement marqu&eacute;s compte tenu des effets thermodynamiques sur les processus physiologiques et le cycle reproductif. Cette th&egrave;se vise &agrave; explorer les effets du climat et de la ph&eacute;nologie de la reproduction sur les traits physiologiques, comportementaux, reproductifs et les traits d&rsquo;histoire de vie des femelles et de leur prog&eacute;niture chez un ectotherme terrestre, le l&eacute;zard vivipare (<em>Zootoca vivipara</em>). Nous avons utilis&eacute; une approche int&eacute;grative combinant des &eacute;tudes transversales et longitudinales afin d&rsquo;explorer les d&eacute;terminants environnementaux, individuels et la s&eacute;lection sur les dates de parturition en milieu naturel ainsi que des &eacute;tudes exp&eacute;rimentales pour quantifier les b&eacute;n&eacute;fices et les co&ucirc;ts de la plasticit&eacute; thermique de la gestation en laboratoire. Les temp&eacute;ratures maximales journali&egrave;res durant la p&eacute;riode d&rsquo;activit&eacute; post-hivernale, la couverture foresti&egrave;re et la taille corporelle &eacute;taient des d&eacute;terminants importants des dates de parturition. Nos r&eacute;sultats mettent en &eacute;vidence une s&eacute;lection directionnelle favorisant une date de parturition pr&eacute;coce, mais une faible capacit&eacute; de r&eacute;ponse &eacute;volutive de ce trait &agrave; la s&eacute;lection. Enfin, l&rsquo;acc&eacute;l&eacute;ration thermique de la gestation induite par le r&eacute;chauffement diurne et/ou nocturne alt&egrave;re l&rsquo;hom&eacute;ostasie maternelle, mais une date de naissance plus pr&eacute;coce a des effets positifs sur la survie et la croissance de la prog&eacute;niture. Dans l&rsquo;ensemble, nos r&eacute;sultats sugg&egrave;rent que l&rsquo;&eacute;tude des cons&eacute;quences des changements ph&eacute;nologiques chez les squamates doit se concentrer sur les limites et la balance co&ucirc;t-b&eacute;n&eacute;fice de la plasticit&eacute; thermique des dates de reproduction.&nbsp;Nous soulignons &eacute;galement l&rsquo;importance de consid&eacute;rer le r&eacute;chauffement nocturne, les ajustements physiologiques et comportementaux pour y faire face, ainsi que l&rsquo;importance de la structure de l&rsquo;habitat pour comprendre et pr&eacute;dire les r&eacute;ponses des ectothermes terrestres face au changement climatique.</span></p>

opencc-by-4.0Oct 2024View details →
ClinicalTrials.gov32/100

Effect of Modifications of Nutritional Intake Upon Reproductive Hormones in Normal Women

ClinicalTrials.gov study NCT02233283. IPD Sharing: Not stated. Countries: 1. Publications: 1.

restrictedIPD-UNDECIDEDFeb 2026View details →
dryad32/100

Data from: Modification of reproductive schedule in response to pathogen exposure in a wild insect: support for the terminal investment hypothesis

Open the record for dataset details and reuse information.

publicAug 2020View details →
geo24/100

Analysis of cell-type-specific chromatin modifications and gene expression in Drosophila neurons that direct reproductive behavior

GEO Series GSE153901. Drosophila melanogaster. 250 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenApr 2021View details →
geo24/100

Analysis of cell-type-specific chromatin modifications and gene expression in Drosophila neurons that direct reproductive behavior [TRAP II]

GEO Series GSE153900. Drosophila melanogaster. 16 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenApr 2021View details →
geo24/100

Analysis of cell-type-specific chromatin modifications and gene expression in Drosophila neurons that direct reproductive behavior [TRAP I]

GEO Series GSE153899. Drosophila melanogaster. 18 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenApr 2021View details →
geo24/100

Analysis of cell-type-specific chromatin modifications and gene expression in Drosophila neurons that direct reproductive behavior [ChIP]

GEO Series GSE154034. Drosophila melanogaster. 216 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenApr 2021View details →
geo24/100

Ectopic application of the repressive histone modification H3K9me2 establishes postzygotic reproductive isolation in Arabidopsis thaliana

GEO Series GSE100011. Arabidopsis thaliana. 60 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.

openGEO-OpenJul 2017View details →
geo16/100

m6A RNA modification controls reproductive development and metabolic adaptation in the human parasite Schistosoma japonicum [m6a-seq]

GEO Series GSE306705. Schistosoma japonicum. 18 samples. Type: Other.

openGEO-OpenSep 2025View details →
geo12/100

m6A RNA modification controls reproductive development and metabolic adaptation in the human parasite Schistosoma japonicum [RNA-seq]

GEO Series GSE306704. Schistosoma japonicum. 4 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2025View details →

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Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record