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5 results for “rhythm generator”
Phase response analyses support a relaxation oscillator model of locomotor rhythm generation in Caenorhabditis elegans
<p>This dataset contains all data and codes that are used in the manuscript entitled "Phase response analyses support a relaxation oscillator model of locomotor rhythm generation in <em>Caenorhabditis elegans</em>".</p> <p>The data include raw videos and intermediate data for optogenetic experiments of all strains, experimental conditions (illumination duration, illuminated region, fluid viscosity and date). Within the parent folder 'Videos', each subfolder represents data of a group of experiments using the same strain under the same condition, as indicated explicitly by the subfolder name. Within each subfolder, there are raw videos of freely moving worms perturbed by transient optogenetic perturbations and intermediate data which include locomotory information and the corresponding figure plots (kymographs) that were generated by analysing the raw videos with the image analysis software (also in the dataset)</p> <p>The codes include scripts for image data analysis and model simulations. The image data analysis codes include scripts specifically for generating phase portrait graphs, phase response curves, head oscillation stability plots, phase isochron map and vector field. The model simulation codes include scripts for model oscillators implementation, paramter estimation/optimization and simulations of optogenetic inhibition.</p>
Phase response analyses support a relaxation oscillator model of locomotor rhythm generation in Caenorhabditis elegans
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Data from: Distributed rhythm generators underlie Caenorhabditis elegans forward locomotion
Coordinated rhythmic movements are ubiquitous in animal behavior. In many organisms, chains of neural oscillators underlie the generation of these rhythms. In C. elegans, locomotor wave generation has been poorly understood; in particular, it is unclear where in the circuit rhythms are generated, and whether there exists more than one such generator. We used optogenetic and ablation experiments to probe the nature of rhythm generation in the locomotor circuit. We found that multiple sections of forward locomotor circuitry are capable of independently generating rhythms. By perturbing different components of the motor circuit, we localize the source of secondary rhythms to cholinergic motor neurons in the midbody. Using rhythmic optogenetic perturbation, we demonstrate bidirectional entrainment of oscillations between different body regions. These results show that, as in many other vertebrates and invertebrates, the C. elegans motor circuit contains multiple oscillators that coordinate activity to generate behavior.
Rhythm Perception and Generation
ClinicalTrials.gov study NCT00080067. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Data from: Distributed rhythm generators underlie Caenorhabditis elegans forward locomotion
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.