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ShareScore release 0.9.0
Dataset results
181 results for “satellite cells”
Extraordinarily rapid proliferation of cultured muscle satellite cells from migratory birds
<p>Migratory birds experience bouts of muscle growth and depletion as they prepare for, and undertake prolonged flight. Our studies of migratory bird muscle physiology <i>in vitro</i> led to the discovery that sanderling (<i>Calidris alba</i>) muscle satellite cells proliferate more rapidly than other normal cell lines. Here we determined the proliferation rate of muscle satellite cells isolated from five migratory species (sanderling; ruff, <i>Calidris pugnax</i>; western sandpiper, <i>Calidris mauri</i>; yellow-rumped warbler, <i>Setophaga coronata</i>; Swainson's thrush, <i>Catharus ustulatus</i>) from two families (shorebirds and songbirds) and with different migratory strategies. Ruff and sanderling satellite cells exhibited rapid proliferation, with population doubling times of 9.3±1.3 and 11.4±2.0 hrs whereas the remaining species' cell doubling times were ≥24 hrs. The results indicate that the rapid proliferation of satellite cells is not associated with total migration distance but may be related to flight bout duration and interact with lifespan.</p>
Single-cell chromatin accessibility profiling reveals a self-renewing muscle satellite cell state
<p><span class="TextRun SCXW101911863 BCX0"><span class="NormalTextRun SCXW101911863 BCX0">A balance between self-renewal and differentiation is critical for the regenerative capacity of tissue-resident stem cells. In skeletal muscle, successful regeneration requires the orchestrated activation, proliferation, and differentiation of muscle satellite cells (</span><span class="SpellingError SCXW101911863 BCX0">MuSCs</span><span class="NormalTextRun SCXW101911863 BCX0">) that are normally quiescent. A subset of </span><span class="SpellingError SCXW101911863 BCX0">MuSCs</span><span class="NormalTextRun SCXW101911863 BCX0"> undergoes self-renewal to replenish the stem cell pool, but the features that identify and define self-renewing </span><span class="SpellingError SCXW101911863 BCX0">MuSCs</span><span class="NormalTextRun SCXW101911863 BCX0"> remain to be elucidated. Here, through single-cell chromatin accessibility analysis, we reveal the self-renewal versus differentiation trajectories of </span><span class="SpellingError SCXW101911863 BCX0">MuSCs</span><span class="NormalTextRun SCXW101911863 BCX0"> over the course of regeneration in vivo. We identify </span><span class="SpellingError SCXW101911863 BCX0">Betaglycan</span><span class="NormalTextRun SCXW101911863 BCX0"> as a unique marker of self-renewing </span><span class="SpellingError SCXW101911863 BCX0">MuSCs</span><span class="NormalTextRun SCXW101911863 BCX0"> that can be purified and efficiently contributes to regeneration after transplantation. We also show that SMAD4 and downstream genes are genetically required for self-renewal </span></span><span class="TextRun SCXW101911863 BCX0"><span class="NormalTextRun SCXW101911863 BCX0">in vivo</span></span><span class="TextRun SCXW101911863 BCX0"><span class="NormalTextRun SCXW101911863 BCX0"> by restricting differentiation. Our study unveils the identity and mechanisms of self-renewing </span><span class="SpellingError SCXW101911863 BCX0">MuSCs</span><span class="NormalTextRun SCXW101911863 BCX0"> while providing a key resource for comprehensive analysis of muscle regeneration.</span></span></p>
In vivo timelapse imaging and analysis of Golgi satellite organelle distribution and movement in the neural progenitor cells of the brain
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Single-cell chromatin accessibility profiling reveals a self-renewing muscle satellite cell state
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Extraordinarily rapid proliferation of cultured muscle satellite cells from migratory birds
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Data from: Immediate and carry-over effects of insect outbreaks on vegetation growth in West Greenland assessed from cells to satellite
Aim: Tundra ecosystems are highly vulnerable to climate change and climate-growth responses of Arctic shrubs are variable and altered by microsite environmental conditions and biotic factors. With warming and drought during the growing season, insect-driven defoliation is expected to increase in frequency and severity with potential broad-scale impacts on tundra ecosystem functioning. Here we provide the first broad-scale reconstruction of spatiotemporal dynamics of past insect outbreaks by assessing their effects on shrub growth along a typical Greenlandic fjord climate gradient from the inland ice to the sea. Location: Nuuk Fjord (64°30′N/51°23′W) and adjacent areas, West Greenland. Taxa: Great brocade (Eurois occulta L.) and grey willow (Salix glauca L.). Methods: We combined dendro-anatomical and remote sensing analyses. Time series of ring width and wood-anatomical traits were obtained from chronologies of > 40 years established from 153 individuals of S. glauca collected at nine sites. We detected anomalies in satellite-based Normalized Difference Vegetation Index (NDVI) related to defoliation and reconstructed past changes in photosynthetic activity across the region. Results: We identified outbreaks as distinctive years with reduced ring width, cell-wall thickness and vessel size, without being directly related to climate but matching with years of parallel reduction in NDVI. The two subsequent years after the defoliation showed a significant increase in ring width. The reconstructed spatiotemporal dynamics of these events indicate substantial regional variation in outbreak intensity linked to the climate variability across the fjord system. Main conclusions: Our results highlight the ability of S. glauca to cope with severe insect defoliation by changing carbon investment and xylem conductivity leading to high resilience and rapid recovery after the disturbance. Our multi-proxy approach allows us to pin-point biotic drivers of narrow ring formation and to provide new broad-scale insight on the C-budget and vegetation productivity of shrub communities in a widespread arctic ecosystem
Coastal Satellite Image Segmentation (Water and Land) Labels: Delmarva (USA), Virginia Beach (USA), New Jersey (USA), Long Island (USA), Duck, NC (USA), Northern Tuscany Littoral Cell (Italy), Torrey Pines, CA, (USA), Narrrabeen Beach (Australia), Truc Vert (France)
<p>Contained here are jpegs containing coastal RGB satellite images along with a water vs. land mask. Each image is 256 pixels by 256 pixels. </p> <p>Geographic scope: Delmarva (USA), Virginia Beach (USA), New Jersey (USA), Long Island (USA), Duck, NC (USA), Northern Tuscany Littoral Cell (Italy), Torrey Pines, CA, (USA), Narrrabeen Beach (Australia), Truc Vert (France)</p> <p>Temporal range: 1984 to 2022</p> <p>Satellites: Landsat 5, 7, 8 and Sentinel-2</p> <p>All images were downloaded from Google Earth Engine using CoastSat download tools.</p> <p>The datasets are arranged into 'train', 'val', and 'test' folders. Within each of those folders are two folders 'a' and 'b'. 'a' contains the images (RGB), whereas 'b' contains the labels (land vs. water mask).</p> <p>All images were augmented with the four following augmentations: horizontal flip, vertical flip, 90 degree clockwise rotation, 90 degree counterclockwise rotation, and a horizontal+vertical flip. </p> <p>For training a new segmentation model, it is advised to not do any of these rotational or flip augmentations since they have already been performed. Instead, possibly experiment with other augmentations like introducing noise into the imagery.</p> <p>These images were used to train an image-to-image translation generative adversarial network. The code and model weights (generator and discriminator) are available at <a href="https://github.com/mlundine/Shoreline_Extraction_GAN">https://github.com/mlundine/Shoreline_Extraction_GAN</a>.</p> <p>To get to the files locally, you can download the .zip from Zenodo and then unzip the .zip file.</p>
Redox Regulation of Satellite Cells and Skeletal Muscle Healing
ClinicalTrials.gov study NCT03711838. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Study of the Biological Function of Muscle Satellite Cells From Patients With Obstetric Brachial Plexus Palsy
ClinicalTrials.gov study NCT05403034. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Skeletal Muscle Regeneration in Survivors of Critical Illness: How to Prevent Satellite Cell Failure?
ClinicalTrials.gov study NCT05671614. IPD Sharing: YES. Countries: 1. Publications: 25.
Data from: Immediate and carry-over effects of insect outbreaks on vegetation growth in West Greenland assessed from cells to satellite
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Functionally heterogeneous human satellite cells identified by single cell RNA sequencing
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Transcriptional profiling of turkey muscle satellite cells transfected with DAP-siRNA during proliferation and differentiation
GEO Series GSE35660. Meleagris gallopavo. 16 samples. Type: Expression profiling by array.
Expression data from differentiating primary culture of equine satellite cells (ESC) β-hydroxy-β-methylbutyrate (HMB)
GEO Series GSE74495. Equus caballus. 4 samples. Type: Expression profiling by array.
mRNA-seq of satellite cells cultured and expanded in F10 conventional medium, T cell conditional medium, and cytokine cocktail
GEO Series GSE58465. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
RNA-Seq of Myf6-knockout versus Wild-type satellite cells
GEO Series GSE133505. Mus musculus. 19 samples. Type: Expression profiling by high throughput sequencing.
Single-cell RNA-Sequencing of young and aged satellite cells, macrophages and fibro-adipogenic progenitor cells
GEO Series GSE171794. Mus musculus. 7 samples. Type: Expression profiling by high throughput sequencing.
Fibronectin regulates Wnt7a signaling and satellite cell expansion
GEO Series GSE59272. Mus musculus. 1 samples. Type: Expression profiling by array; Third-party reanalysis.
Human pluripotent stem cell-derived myogenic progenitor cells engraft to become quiescent functional satellite cells in vivo
GEO Series GSE165075. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
RNA-seq analysis of Piezo1-deficient muscle satellite cells
GEO Series GSE217417. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.