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ShareScore release 0.9.0
Dataset results
27 results for “sensory receptor”
Data from "Robust sensory traits across light habitats: Visual signals but not receptors vary in centrarchids inhabiting distinct photic environments"
<p>Visual communication in fish is often shaped by the light environment they inhabit, influencing both sensory (e.g., eye size, opsin gene expression), and signaling traits (e.g., body reflectance). This study explores the phenotypic variation in the visual communication traits of six species of centrarchids (Centrarchidae) inhabiting two contrasting light environments. We measured morphological, molecular, and signaling traits to determine their responses to photic conditions. Our findings reveal significant interspecific variation in sensory traits but no consistent phenotypic variation between light environments. Centrarchids showed robust visual systems with red-green dichromatic vision, which was largely unaffected by the different light habitats. We also found significant molecular evolution in the visual opsin genes, although these changes were not associated with environmental conditions. However, body reflectance displayed species-specific responses to environmental conditions, suggesting that signaling traits may be more flexible than sensory traits. Overall, our results challenge the generality of the current paradigm in visual ecology, which portrays visual systems in fish as highly tunable owing to photic conditions. Our study highlights the potential evolutionary or developmental constraints on centrarchid visual systems and their implications for adaptability to various habitats and novel environmental threats.</p> <p>This dataset includes underwater light measurements, retinal transcriptomics, eye morphology, and spectral reflectance data to assess the effects of environment and species identity on eye size, opsin gene expression, chromophore usage, and body reflectance of centrarchids. Furthermore, we test for signatures of molecular evolution on the amino acid sequence of visual opsin genes across species and populations. By combining data on the visual ecology of different species from two distinct light environments, we ask i) do the visual traits of centrarchids vary across photic environments? and ii) are phenotypic responses to light conditions shared among species or are they species-specific? Overall, we found robust visual systems across species (no environmental effect) but variable body reflectance across species and environments (genotype-by-environment interaction, G × E). This suggests that divergent species-specific responses in signaling might help offset the lack of fine-tuning in the visual system of centrarchids. </p> <p>For more information see ReadMe file.</p>
Data from: Synergism, bifunctionality, and the evolution of a gradual sensory trade-off in hummingbird taste receptors
<p>Sensory receptor evolution can imply trade-offs between ligands, but the extent to which such trade-offs occur and the underlying processes shaping their evolution is not well understood. For example, hummingbirds have re-purposed their ancestral savory receptor (T1R1-T1R3) to detect sugars, but the impact of this sensory shift on amino acid perception is unclear. Here, we use functional and behavioral approaches to show that the hummingbird T1R1-T1R3 acts as a bifunctional receptor responsive to both sugars and amino acids. Our comparative analyses reveal substantial functional diversity across the hummingbird radiation and suggest an evolutionary timeline for T1R1-T1R3 re-tuning. Finally, we identify a novel form of synergism between sugars and amino acids in vertebrate taste receptors. This work uncovers an unexplored axis of sensory diversity, suggesting new ways in which nectar chemistry and pollinator preferences can coevolve.</p>
SEGATROM: Sensory and Gastrointestinal Impact of Taste Receptor Variants on Human Metabolism and Nutrition
ClinicalTrials.gov study NCT02219295. IPD Sharing: Not stated. Countries: 1. Publications: 2.
A Randomized, Double-blind, Placebo- and Active-controlled Study of the Electric Current Effects of ABT-639 on the Spontaneous Activity of Pain Sensory Receptors in Patients With Diabetic Peripheral N
ClinicalTrials.gov study NCT01589432. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Data from: Synergism, bifunctionality, and the evolution of a gradual sensory trade-off in hummingbird taste receptors
Open the record for dataset details and reuse information.
Prior activity of olfactory receptor neurons is required for proper sensory processing and behavior in Drosophila larvae
GEO Series GSE111334. Drosophila melanogaster. 9 samples. Type: Expression profiling by high throughput sequencing.
Evolutionary Process Underlying Receptor Gene Expansion and Cellular Divergence of Olfactory Sensory Neurons in Honeybees. [scATAC-Seq]
GEO Series GSE248096. Apis mellifera. 3 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Silencing of odorant receptor gene expression by G protein βγ signaling ensures the expression of one odorant receptor per olfactory sensory neuron
GEO Series GSE53334. Danio rerio. 6 samples. Type: Expression profiling by high throughput sequencing.
HDAC2 in primary sensory neurons constitutively restrains chronic pain by repressing α2δ-1 expression and associated NMDA receptor activity
GEO Series GSE145125. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Development of specialized sensory neurons engages a nuclear receptor required for functional plasticity
GEO Series GSE162002. Caenorhabditis elegans. 16 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
CD20 is a mammalian odorant receptor expressed in a subset of olfactory sensory neurons that mediates innate avoidance of predators
GEO Series GSE240378. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Evolutionary Process Underlying Receptor Gene Expansion and Cellular Divergence of Olfactory Sensory Neurons in Honeybees
GEO Series GSE248097. Apis mellifera. 6 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Estrogen Modulation of the Pronociceptive Effects of Serotonin on Female Rat Trigeminal Sensory Neurons is Timing- and Dosage-Dependent and Requires Estrogen Receptor Alpha
GEO Series GSE193773. Rattus norvegicus. 12 samples. Type: Expression profiling by high throughput sequencing.
GABAB receptor modulation of membrane excitability in human pluripotent stem cell-derived sensory neurons by baclofen and α-conotoxin Vc1.1
GEO Series GSE282901. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
Identification of sensory receptors in murine liver
GEO Series GSE157843. Mus musculus. 2 samples. Type: Expression profiling by RT-PCR.
Transcriptome analysis of mouse olfactory sensory neurons expressing 3 different types of olfactory receptor
GEO Series GSE169010. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Touch receptor end-organ innervation and function requires sensory expression of the transcription factor Meis2
GEO Series GSE223788. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Data from: Gonadotropin-releasing hormone receptor (Gnrhr) gene knock out: normal growth and development of sensory, motor and spatial orientation behavior but altered metabolism in neonatal and prepubertal mice
Open the record for dataset details and reuse information.
Evolutionary Process Underlying Receptor Gene Expansion and Cellular Divergence of Olfactory Sensory Neurons in Honeybees. [scRNA-Seq]
GEO Series GSE248095. Apis mellifera. 3 samples. Type: Expression profiling by high throughput sequencing.
Odorant Receptor Expression Frequency in Mature Olfactory Sensory Neurons Depends Lhx2 [OmpCre:Emx2]
GEO Series GSE74523. Mus musculus. 8 samples. Type: Expression profiling by array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.