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45 results for “short-chain fatty acids”
Supplementation of Heat-treated Lactiplantibacillus plantarum nF1 Changes the Production of Short-chain Fatty Acids in Healthy Infants
<p><strong>BACKGROUND:</strong> Imbalance of the gut microbiome and decrease in the number of short-chain fatty acid (SCFA)-producing bacteria often affect human health by altering intestinal and immune homeostasis. Probiotic use is an attractive method for modulating gut microbiota to prevent or treat intestinal dysbiosis. This study aimed to determine whether the oral consumption of heat-treated <em>Lactiplantibacillus plantarum</em> nF1 (HLp-nF1) induces changes in the gut environment in healthy infants by measuring changes in fecal SCFAs. <strong>METHODS:</strong> The study enrolled 43 infants aged <2 months, with 30 infants in the HLp-nF1 group receiving HLp-nF1 orally (2.5 × 10<sup>12</sup> cells/g/pack, daily dose of two packs) for 8 weeks. The fecal samples were collected and the questionnaires were administered at weeks 0 and 8. <strong>RESULTS:</strong> The concentrations of the total SCFAs, acetate, propionate, and butyrate significantly increased following HLp-nF1 supplementation (P < 0.0001, P < 0.0001, P < 0.0001, and P = 0.028, respectively). Additionally, gut microbiota composition was altered in the HLp-nF1 group. <strong>CONCLUSIONS:</strong> Using probiotics is a useful and easy method for manipulating SCFA formation by altering the human gut microbiota composition.</p>
Longitudinal Evaluation of Short-Chain Fatty Acid Profiles During the Natural Disease Course and a Mediterranean Diet Intervention in Amyotrophic Lateral Sclerosis Patients
ClinicalTrials.gov study NCT07178067. IPD Sharing: NO. Countries: 1. Publications: 0.
The Role of Short-chain Fatty Acids in Malnutrition on Stress, Eating Behavior, and Nutritional State
ClinicalTrials.gov study NCT06064201. IPD Sharing: YES. Countries: 1. Publications: 1.
Effects of Short-chain Fatty Acids on Inflammatory and Metabolic Parameters in Maintenance Hemodialysis
ClinicalTrials.gov study NCT02976688. IPD Sharing: NO. Countries: 0. Publications: 33.
Short-chain fatty acids improve post-stroke recovery via immunological mechanisms.
GEO Series GSE131788. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Gut-derived short-chain fatty acids modulate skin barrier integrity by promoting keratinocyte metabolism and differentiation
GEO Series GSE185640. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Sex-dependent amelioration of laser-induced choroidal neovascularization by Short-Chain Fatty Acid treatment in a mouse model
GEO Series GSE299691. Mus musculus. 43 samples. Type: Expression profiling by high throughput sequencing.
Microbial short-chain fatty acids regulate drug seeking and transcriptional control in a model of cocaine seeking.
GEO Series GSE227980. Rattus norvegicus. 20 samples. Type: Expression profiling by high throughput sequencing.
B cell-intrinsic epigenetic modulation of antibody responses by dietary fiber-derived short-chain fatty acids
GEO Series GSE140111. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing.
16S rRNA sequencing data of cecal digesta in goats infusion of three short-chain fatty acids
GEO Series GSE232036. Capra hircus. 24 samples. Type: Other.
Microbiota-derived short-chain fatty acids modulate expression of Campylobacter jejuni determinants required for commensalism and virulence
GEO Series GSE86327. Campylobacter jejuni. 18 samples. Type: Expression profiling by array.
Supplementation with short-chain fatty acids and a prebiotic improves clinical outcome in Parkinson’s disease: A randomized double-blind prospective study [RNA-Seq]
GEO Series GSE296011. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
The Impact of Daily Intake of Short-chain Fatty Acids on Cardiometabolic Risk Factors in Individuals at Risk for Metabolic Syndrome
ClinicalTrials.gov study NCT06951386. IPD Sharing: NO. Countries: 1. Publications: 0.
The Impact of Short-Chain Fatty Acids on Gut Hormone Release After Delivery in the Small and Large Intestine of Healthy Volunteers
ClinicalTrials.gov study NCT06686888. IPD Sharing: NO. Countries: 1. Publications: 0.
Metabolic Effects of Short-Chain Fatty Acids in Healthy Individuals
ClinicalTrials.gov study NCT07183488. IPD Sharing: NO. Countries: 1. Publications: 0.
Effect of Short-chain Fatty Acids on Aerobic Endurance
ClinicalTrials.gov study NCT06054607. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Brain Responses to Short-Chain Fatty Acid Intervention
ClinicalTrials.gov study NCT06546683. IPD Sharing: YES. Countries: 1. Publications: 0.
Effects of the Short-Chain Fatty Acids-Targeted Dietary Interventions on the Selected Autonomic Functions in Humans
ClinicalTrials.gov study NCT06851039. IPD Sharing: NO. Countries: 1. Publications: 0.
The Systemic Concentration of Short-Chain Fatty Acids After Delivery in the Small and Large Intestine of Healthy Volunteers
ClinicalTrials.gov study NCT06082726. IPD Sharing: NO. Countries: 1. Publications: 0.
Supplementation with short-chain fatty acids and a prebiotic improves clinical outcome in Parkinson’s disease: A randomized double-blind prospective study
GEO Series GSE296010. feces metagenome. 20 samples. Type: Other.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.