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187 results for “skin diseases”
Assessment of skin autofluorescence and its association with glycated hemoglobin, cardiovascular risk markers and concomitant chronic diseases in children with type 1 diabetes
<p>This is the dataset for the publication "Assessment of skin autofluorescence and its association with glycated hemoglobin, cardiovascular risk markers and concomitant chronic diseases in children with type 1 diabetes".</p>
Sociality and tattoo skin disease among bottlenose dolphins in Shark Bay, Australia
<p></p><p>Social behavior is an important driver of infection dynamics, though identifying the social interactions that foster infectious disease transmission is challenging. Here we examine how social behavior impacts disease transmission in Indo-Pacific bottlenose dolphins (Tursiops aduncus) using an easily identifiable skin disease and social network data. We analyzed tattoo skin disease (TSD) lesions based on photographs collected as part of a 34-year longitudinal study in relation to the sociality of T. aduncus using three metrics (degree, time spent socializing, and time in groups) and network structure, using the k-test. We show that calves with TSD in the second year of life associated more with TSD-positive individuals in the first year of life compared with calves that did not have TSD. Additionally, the network k-test showed that the social network links are epidemiologically relevant for transmission. However, degree, time spent in groups, and time spent socializing were not significantly different between infected and uninfected groups. Our findings indicate that association with infected individuals is predictive of an individual's risk for TSD and that the social association network can serve as a proxy for studying the epidemiology of skin diseases in bottlenose dolphins.</p><p></p>
Synoptic table for surveillance scenarios for lumpy skin disease
<p>The Standing Group of Experts on lumpy skin disease (LSD) for South-East Europe under the GF-TADs umbrella recommended that all countries in South-East Europe, affected or at risk for LSD, should collaborate within the GF-TADs to draft a regional roadmap on an LSD exit strategy from 2018 onwards. This recommendation has triggered a mandate to EFSA in which it is asked to assess the effectiveness of different surveillance systems with different objectives, i.e. early detection or demonstration of freedom from disease, in the following contexts:</p> <p>(a) in areas or countries at risk of LSD, where no LSD outbreaks have occurred and LSD vaccination was never carried out;</p> <p>(b) in areas or countries at risk of LSD, where no LSD outbreaks have occurred and where LSD vaccination is carried out;</p> <p>(c) in areas where no LSD outbreaks have occurred and LSD preventive vaccination was carried out, and then stopped;</p> <p>(d) in areas where LSD outbreaks have been confirmed, and vaccination is stopped.</p> <p>For planning surveillance several elements should be considered: the objectives and related design prevalence, the epidemiological situation, the immunological status of the host population, the geographical area and the season, the type of surveillance (active or passive), the diagnostic methods including clinical detection (considered the most effective method for early detection of LSD), the target population, the sample size and frequency. Here a synoptic table is presented where each of these elements are discussed for each of the four scenarios given above.</p>
Synoptic table for surveillance scenarios for lumpy skin disease
<p>The Standing Group of Experts on lumpy skin disease (LSD) for South-East Europe under the GF-TADs umbrella recommended that all countries in South-East Europe, affected or at risk for LSD, should collaborate within the GF-TADs to draft a regional roadmap on an LSD exit strategy from 2018 onwards. This recommendation has triggered a mandate to EFSA in which it is asked to assess the effectiveness of different surveillance systems with different objectives, i.e. early detection or demonstration of freedom from disease, in the following contexts:</p> <p>(a) in areas or countries at risk of LSD, where no LSD outbreaks have occurred and LSD vaccination was never carried out;</p> <p>(b) in areas or countries at risk of LSD, where no LSD outbreaks have occurred and where LSD vaccination is carried out;</p> <p>(c) in areas where no LSD outbreaks have occurred and LSD preventive vaccination was carried out, and then stopped;</p> <p>(d) in areas where LSD outbreaks have been confirmed, and vaccination is stopped.</p> <p>For planning surveillance several elements should be considered: the objectives and related design prevalence, the epidemiological situation, the immunological status of the host population, the geographical area and the season, the type of surveillance (active or passive), the diagnostic methods including clinical detection (considered the most effective method for early detection of LSD), the target population, the sample size and frequency. Here a synoptic table is presented where each of these elements are discussed for each of the four scenarios given above.</p>
Azithromycin - Ivermectin Mass Drug Administration for Skin Disease
ClinicalTrials.gov study NCT02775617. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Effisayil™ 1: A Study to Test Spesolimab (BI 655130) in Patients With a Flare-up of a Skin Disease Called Generalized Pustular Psoriasis
ClinicalTrials.gov study NCT03782792. IPD Sharing: NO. Countries: 12. Publications: 5.
A Study to Test How Effective and Safe Different Doses of BI 655130 Are in Patients With a Moderate to Severe Form of the Skin Disease Palmoplantar Pustulosis
ClinicalTrials.gov study NCT04015518. IPD Sharing: NO. Countries: 15. Publications: 2.
Usefulness of α-synuclein as a Marker for Early Diagnosis of Parkinson's Disease in Skin Biopsy.
ClinicalTrials.gov study NCT01380899. IPD Sharing: NO. Countries: 1. Publications: 10.
Study of Subcutaneous (Injected Under the Skin) Risankizumab to Assess Change in Disease Symptoms in Adult Participants With Moderate to Severe Plaque Psoriasis With Palmoplantar Involvement
ClinicalTrials.gov study NCT04713592. IPD Sharing: YES. Countries: 4. Publications: 0.
Melanoma of the Skin and Exposure to Solar Ultraviolet Radiation at Work in Modena Territory: a Case-control Study to Promote an Active Search and Prevention of Occupational Diseases Based on Recent I
ClinicalTrials.gov study NCT07251335. IPD Sharing: NO. Countries: 1. Publications: 7.
Study Evaluating Etanercept on Skin and Joint Disease in Psoriatic Arthritis
ClinicalTrials.gov study NCT00245960. IPD Sharing: YES. Countries: 26. Publications: 6.
Imatinib Mesylate to Treat Skin Changes in Patients With Chronic Graft-Versus-Host Disease
ClinicalTrials.gov study NCT00702689. IPD Sharing: NO. Countries: 1. Publications: 2.
Data from: El Niño drives a widespread ulcerative skin disease outbreak in Galapagos marine fishes
Open the record for dataset details and reuse information.
Data from: Imperfect pathogen detection from non-invasive skin swabs biases disease inference
Open the record for dataset details and reuse information.
Sociality and tattoo skin disease among bottlenose dolphins in Shark Bay, Australia
Open the record for dataset details and reuse information.
Data for Galaxy training in assembly of Lumpy Skin Disease Virus Genome
<p>This upload was to support a Galaxy tutorial on the Lumpy Skin Disease virus genome prepared by the Defend2020 project. To access the data deposited in Genbank and the Sequence Read Archive please refer to the following deposits.</p> <p>The LSDV isolate Kubash/KAZ/16 sequence has been deposited in GenBank under accession number <a href="https://www.ncbi.nlm.nih.gov/nuccore/MN642592">MN642592</a>, and raw data have been submitted to the SRA under BioProject number <a href="https://www.ncbi.nlm.nih.gov/bioproject/PRJNA587601/">PRJNA587601</a>.</p>
Data from: Skin autofluorescence and subclinical atherosclerosis in mild to moderate chronic kidney disease: a case-control study
Advanced glycation end-products (AGEs) are increased and predict mortality in patients with chronic kidney disease (CKD) who are undergoing hemodialysis, irrespective of the presence of type 2 diabetes. However, little information exits about the relationship between AGEs and subclinical atherosclerosis at the early stages of CKD. A case-control study was performed including 87 patients with mild-to-moderate stages of CKD (glomerular filtration rate from 89 to 30 ml/min/per 1.73m2) and 87 non-diabetic non-CKD subjects matched by age, gender, body mass index, and waist circumference. Skin autofluorescence (AF), a non-invasive assessment of AGEs, was measured. The presence of atheromatous disease in carotid and femoral arteries was evaluated using vascular ultrasound, and vascular age and SCORE risk were estimated. Patients with mild-to-moderate stages of CKD showed an increase in skin AF compared with control subjects (2.5±0.6 vs. 2.2±0.4 AU, p<0.001). A skin AF value >2.0 AU was accompanied by a 3-fold increased risk of detecting the presence of an atheromathous plaque (OR 3.0, 95% CI 1.4–6.5, p = 0.006). When vascular age was assessed through skin AF, subjects with CKD were almost 12 years older than control subjects (70.3±25.5 vs. 58.5±20.2 years, p = 0.001). Skin AF was negatively correlated with glomerular filtration rate (r = -0.354, p<0.001) and LDL-cholesterol (r = -0.269, p = 0.001), and positively correlated with age (r = 0.472, p<0.001), pulse pressure (r = 0.238, p = 0.002), and SCORE risk (r = 0.451, p<0.001). A stepwise multivariate regression analysis showed that age and glomerular filtration rate independently predicted skin AF (R2 = 0.289, p<0.001). Skin AF is elevated in patients with mild-to-moderate CKD compared with control subjects. This finding may be independently associated with the glomerular filtration rate and the presence of subclinical atheromatous disease. Therefore, the use of skin AF may help to accurately evaluate the real cardiovascular risk at the early stages of CKD.
Fig. 2 in Antimicrobial and antioxidant efficacy of Citrus limon L. peel extracts used for skin diseases by Xhosa tribe of Amathole District, Eastern Cape, South Africa
Fig. 2. Nitric oxide scavenging activity of Citrus limon extracts. Results are means of 3 replicates.
Data from: Seasonal and ontogenetic variation of skin microbial communities and relationships to natural disease dynamics in declining amphibians
Recently, microbiologists have focused on characterizing the probiotic role of skin bacteria for amphibians threatened by the fungal disease chytridiomycosis. However, the specific characteristics of microbial diversity required to maintain health or trigger disease are still not well understood in natural populations. We hypothesized that seasonal and developmental transitions affecting susceptibility to chytridiomycosis could also alter the stability of microbial assemblages. To test our hypothesis, we examined patterns of skin bacterial diversity in two species of declining amphibians (Lithobates yavapaiensis and Eleutherodactylus coqui) affected by the pathogenic fungus Batrachochytrium dendrobatidis (Bd). We focused on two important transitions that affect Bd susceptibility: ontogenetic (from juvenile to adult) shifts in E. coqui and seasonal (from summer to winter) shifts in L. yavapaiensis. We used a combination of community-fingerprinting analyses and 16S rRNA amplicon sequencing to quantify changes in bacterial diversity and assemblage composition between seasons and developmental stages, and to investigate the relationship between bacterial diversity and pathogen load. We found that winter-sampled frogs and juveniles, two states associated with increased Bd susceptibility, exhibited higher diversity compared with summer-sampled frogs and adult individuals. Our findings also revealed that hosts harbouring higher bacterial diversity carried lower Bd infections, providing support for the protective role of bacterial communities. Ongoing work to understand skin microbiome resilience after pathogen disturbance has the potential to identify key taxa involved in disease resistance.
Transcriptomic analysis demonstrates the expression, origin and function of lncRNAs in multiple skin diseases
<p>Transcriptomic analysis demonstrates the expression, origin and function of lncRNAs in multiple skin diseases</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.