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datasets available to search
ShareScore release 0.9.0
Dataset results
52 results for “snRNAseq”
Processed snRNAseq data from female Aedes aegypti antennal neurons
<p>Single-nucleus RNA sequencing data accompanying Adavi et al. 2024 <em>bioRxiv </em>preprint: https://doi.org/10.1101/2024.08.21.608847</p> <p>For analysis scripts see: https://github.com/mcbridelab/Adavi_2024_snRNAseqAaegAntennae</p> <p>For raw sequencing files see NCBI BioProject: PRJNA1138769</p>
Olfactory bulb snRNAseq dataset for Team Schlossmacher- ASAP
<p>C57BL/6 mice were nasally inoculated with either a control AAV (AAV-EF1a-TdTomato, B1-4) or an experimental AAV expressing humanized mutant alpha-synuclein (AAV-EF1a-SNCA(A53T), A1-4). The mice were 8 weeks of age at the time of inoculation and the virus was expressed for 4 weeks before the mice were sacrificed and the olfactory bulbs were collected for snRNAseq. Viral transduction of olfactory sensory neurons was confirmed in all 8 samples via cryosectioning of the contralateral olfactory bulb.</p>
MERFISH and snRNAseq analysis of healthy and disease human liver
<p>Single-cell RNA sequencing (scRNA-seq) has advanced our understanding of cell types and their heterogeneity within the human liver, but the spatial organization at single-cell resolution has not yet been described. Here we apply multiplexed error robust fluorescent in situ hybridization (MERFISH) to map the zonal distribution of hepatocytes, resolve subsets of macrophage and mesenchymal populations, and investigate the relationship between hepatocyte ploidy and gene expression within the healthy human liver. We next integrated spatial information from MERFISH with the more complete transcriptome produced by single- nucleus RNA sequencing (snRNA-seq), revealing zonally enriched receptor-ligand interactions. Finally, analysis of fibrotic liver samples identified two hepatocyte populations that are not restricted to zonal distribution and expand with injury. Together these spatial maps of the healthy and fibrotic liver provide a deeper understanding of the cellular and spatial remodeling that drives disease which, in turn, could provide new avenues for intervention and further study.</p>
Mouse Brain snRNASeq Demo Dataset for Cellxgene VIP
<p>snRNASeq data generated at Biogen from 3 control mouse brains. Each brain picked 3 brain regions.</p> <p>Animal IDs 1, 4 and 7</p> <p>Brain region codes:<br> W: WhiteMatter<br> H: Hippo<br> G: GreyMatter</p> <p>10X standard mm10 (3.0.0) reference was used, on cellranger 5.0.0 with --include-introns on.<br> </p>
Mouse Brain snRNASeq and Visium Demo Dataset for CelEry
<p>## snRNASeq data generated from control mouse brain 3 brain regions.</p> <p>Animal IDs 7</p> <p>Brain region codes:<br> 7W-1: WhiteMatter<br> 7H-1: Hippo<br> 7G-1: GreyMatter</p> <p>10X standard mm10 (3.0.0) reference was used, on cellranger 5.0.0 with --include-introns on.</p> <p><br> ## Visium data generated from the same animal control mouse full half brains</p> <p>Animal IDs 14 (075B slice)</p> <p>10X standard mm10 (2020-A) reference and spaceranger 1.1.0 was used<br> </p>
MERFISH and snRNAseq analysis of healthy and disease human liver
Open the record for dataset details and reuse information.
snRNAseq RAT HEART WT BMD and DMD 12months
GEO Series GSE233158. Rattus norvegicus. 3 samples. Type: Expression profiling by high throughput sequencing.
Aberrant mRNA Splicing and Impaired Hippocampal Neurogenesis in Grin2b Mutant Mice [grin2b_snRNAseq]
GEO Series GSE306925. Mus musculus. 32 samples. Type: Expression profiling by high throughput sequencing.
Self-Organized Generation Of Hepatic Cord Like Organoids (HCLOs) With Zonal Diversity (snRNAseq)
GEO Series GSE222648. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
Immune checkpoint TIM-3 regulates microglia and Alzheimer’s disease [snRNAseq_5M]
GEO Series GSE223423. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Single nucleus RNA sequence (snRNAseq) analysis of the spectrum of trophoblast lineages generated from human pluripotent stem cells in vitro
GEO Series GSE171768. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Alzheimer’s disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model [snRNAseq]
GEO Series GSE254104. Mus musculus. 27 samples. Type: Expression profiling by high throughput sequencing.
Tlr7 Drives Sex Differences in Age- and AD-related Demyelination [snRNAseq]
GEO Series GSE282329. Mus musculus. 95 samples. Type: Expression profiling by high throughput sequencing.
Dynamic fibroblast-immune interactions shape recovery after brain injury [snRNASeq_Tgfb]
GEO Series GSE254163. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Dynamic fibroblast-immune interactions shape recovery after brain injury [snRNASeq_Cxcl12]
GEO Series GSE293682. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Spinal cord single-nuclei RNA sequencing of human ALS spinal cords [ALS human snRNAseq]
GEO Series GSE287257. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Adipose tissue retains an epigenetic memory of obesity after weight loss [snRNAseq]
GEO Series GSE236579. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
A Dominant mutation in Dnmt1 leads epigenetic changes (scRNAseq and snRNAseq)
GEO Series GSE169097. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Right atrial snRNAseq analysis
GEO Series GSE291976. Sus scrofa domesticus. 8 samples. Type: Expression profiling by high throughput sequencing.
INFLAMMATION-INDUCED SENESCENT-LIKE GLIA REWIRE CELLULAR NETWORKS IN MULTIPLE SCLEROSIS [snRNAseq Brain]
GEO Series GSE277430. Homo sapiens. 23 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.