Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
23
datasets available to search
ShareScore release 0.9.0
Dataset results
23 results for “somatic growth”
Lingering legacies: Past growth and parental experience influence somatic growth in a fish population
<p>Body size and growth rate can influence individual and population success by mediating fitness. Understanding the factors that influence growth can be difficult to disentangle, however, because growth can be shaped by environmental conditions recently experienced, as well as legacy effects from conditions experienced earlier in life and by parents (via parental effects). To improve understanding of growth among annual cohorts (1982-2015) of Lake Erie Walleye (<em>Sander vitreus</em>), a species with life history and growth characteristics similar to many other long-lived, iteroparous fishes, we determined the role of the following hypothesized factors: H1) recent environmental conditions; H2) traits and experiences of the cohort, including growth, in the previous year; H3) early-life cohort density; H4) early-life body size; and H5) parental composition and environment. We evaluated the relative importance of these hypothesized factors using piecewise structural equation modeling in an information-theoretic framework. Our results indicated that cohort-specific growth of Lake Erie Walleye was most strongly influenced by traits (growth) and experiences of the cohort during the previous year (H2) and parental composition and environment (H5). The observed negative relationship with growth during the previous year may indicate that Walleye exhibits compensatory growth. The relationships with parental sizes and environments may mean that parental contributions to offspring affect cohorts into adulthood, with serious implications for the effects of climate change. Warm winters appear to negatively influence offspring growth performance for many years. Legacy effects had a stronger influence on cohort growth than recent environmental conditions, providing a new understanding of how somatic growth is regulated in Lake Erie's Walleye population. Specifically, the parental composition and environment appear important via epigenetic and/or egg-provisioning legacies, with carryover effects modifying growth over the years. Ultimately, our findings demonstrate that understanding recent growth in animal populations similar to Lake Erie Walleye may require knowledge of past conditions, including those experienced by parents.</p>
Lingering legacies: Past growth and parental experience influence somatic growth in a fish population
Open the record for dataset details and reuse information.
UCSB SONGS Mitigation Monitoring: Reef Survey - Fish Fecundity, Feeding, and Somatic Growth
These data describe annual estimates of the fecundity, gut fullness, and somatic growth of five fish species at three subtidal reefs collected as part of the San Onofre Nuclear Generating Station (SONGS) Mitigation Monitoring Program. Data collection began in 2009 at an artificial reef (Wheeler North Reef in Orange County, CA) and two natural reference reefs (San Mateo Kelp in Orange County, CA and Barn Kelp in San Diego County, CA). Fish were collected annually at each reef between May and October.
Data from: SMAD4 promotes somatic-germline contact during murine oocyte growth
<p>Development of the mammalian oocyte requires physical contact with the surrounding granulosa cells of the follicle, which provide it with essential nutrients and regulatory signals. This contact is achieved through specialized filopodia, termed transzonal projections (TZPs), that extend from the granulosa cells to the oocyte surface. Transforming growth factor (TGFβ) family ligands produced by the oocyte increase the number of TZPs, but how they do so is unknown. Using an inducible Cre recombinase strategy together with expression of green fluorescent protein to verify Cre activity in individual granulosa cells, we examined the effect of depleting the canonical TGFβ mediator, SMAD4. We observed a 20-50% decrease in the total number of TZPs in SMAD4-depleted granulosa cell-oocyte complexes, and a 50% decrease in the number of newly generated TZPs when the granulosa cells were reaggregated with granulosa cell-free wild-type oocytes. Three-dimensional image analysis revealed that TZPs of SMAD4-depleted cells were also longer than controls and more frequently oriented towards the oocyte. Strikingly, the transmembrane proteins, N-cadherin and Notch2, were reduced by 50% in these cells. SMAD4 may thus modulate a network of cell adhesion proteins that stabilize the attachment of TZPs to the oocyte, thereby amplifying signalling between the two cell types.</p>
Data from: SMAD4 promotes somatic-germline contact during murine oocyte growth
Open the record for dataset details and reuse information.
Data from: Pay up or die: Tradeoffs between costly telomere maintenance, somatic growth, and body condition in embryonic and adult sand lizards
Open the record for dataset details and reuse information.
Effect on Early Somatic Growth of a Daily Kinesthetic Stimulation on Preterm Infants
ClinicalTrials.gov study NCT03574350. IPD Sharing: NO. Countries: 1. Publications: 3.
Data from: Crosstalk between growth and somatic maintenance in young animals
Open the record for dataset details and reuse information.
Data from: Carry-over effects of early thermal conditions on somatic and germline oxidative damages are mediated by compensatory growth in sticklebacks
Open the record for dataset details and reuse information.
Data from: Density regulation in Northeast Atlantic fish populations: density dependence is stronger in recruitment than in somatic growth
1. Population regulation is a central concept in ecology, yet in many cases its presence and the underlying mechanisms are difficult to demonstrate. The current paradigm maintains that marine fish populations are predominantly regulated by density-dependent recruitment. 2. While it is known that density-dependent somatic growth can be present too, its general importance is unknown and most practical applications neglect it. This study aimed to close this gap by for the first time quantifying and comparing density dependence in growth and recruitment over a large set of fish populations. 3. We fitted density-dependent models to time series data on population size, recruitment and age-specific weight from commercially exploited fish populations in the Northeast Atlantic Ocean and the Baltic Sea. Data were standardised to enable a direct comparison within and among populations, and estimated parameters were used to quantify the impact of density regulation on population biomass. 4. Statistically significant density dependence in recruitment was detected in a large proportion of populations (70%) whereas for density dependence in somatic growth the prevalence of density dependence depended heavily on the method (26% and 69%). Despite age-dependent variability, the density dependence in recruitment was consistently stronger among age groups and between alternative approaches that use weight-at-age or weight increments to assess growth. Estimates of density-dependent reduction of biomass underlined these results: 97% of populations with statistically significant parameters for growth and recruitment showed a larger impact of density-dependent recruitment on population biomass. 5. The results reaffirm the importance of density-dependent recruitment in marine fishes, yet they also show that density dependence in somatic growth is not uncommon. Further, the results are important from an applied perspective because density dependence in somatic growth affects productivity and catch composition, and therefore the benefits of maintaining fish populations at specific densities.
Data from: Density regulation in Northeast Atlantic fish populations: density dependence is stronger in recruitment than in somatic growth
Open the record for dataset details and reuse information.
Somatic PRDM2 c.4459delA mutations in colorectal cancers control histone methylation and tumor growth
GEO Series GSE80033. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Growth signaling promotes H2A.Z deposition by SRCAP to sustain somatic tissue regeneration [RNA-Seq]
GEO Series GSE278641. Homo sapiens. 42 samples. Type: Expression profiling by high throughput sequencing.
Influence of varying dietary ratios of ω6 to ω3 fatty acids on the hepatic global gene expression, and association with phenotypic traits (growth, somatic indices and tissue lipid composition) in Atla
GEO Series GSE139418. Salmo salar. 16 samples. Type: Expression profiling by array.
Efficacy of Triplet Combination With Pembrolizumab, Neratinib, and Paclitaxel as a Second Line Treatment in Recurrent/Advanced Gastric Cancer Having Somatic Human Epidermal Growth Factor Receptor Fami
ClinicalTrials.gov study NCT05512182. IPD Sharing: NO. Countries: 1. Publications: 0.
Stc2a inhibits IGF-stimulated somatic growth in favor of organismal survival under hypoxic stress
GEO Series GSE311532. Danio rerio. 7 samples. Type: Expression profiling by high throughput sequencing.
Systematic Analysis of Long Intergenic Non-Coding RNAs in C. elegans Germline Uncovers Roles in Somatic Growth
GEO Series GSE154322. Caenorhabditis elegans. 6 samples. Type: Expression profiling by high throughput sequencing.
DAF-16/FoxO and EGL-27/GATA promote developmental growth in response to persistent somatic DNA damage [N2, daf-2, daf-16, daf-2;daf-16]
GEO Series GSE51162. Caenorhabditis elegans. 36 samples. Type: Expression profiling by array.
Growth signaling promotes H2A.Z deposition by SRCAP to sustain somatic tissue regeneration [ChIP-Seq]
GEO Series GSE278642. Homo sapiens. 30 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
DAF-16/FoxO and EGL-27/GATA promote developmental growth in response to persistent somatic DNA damage
GEO Series GSE47778. Caenorhabditis elegans. 51 samples. Type: Expression profiling by array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.