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36 results for “space flight”
Third harmonic generation images of the lacuno-canalicular network in bone femoral diaphysis of mice from the BionM1 project (space flight)
<p>Data set for 11 samples in 3 groups of Control, Space Flight and Synchro (ground control with space flight housing and feeding conditions). Contains THG images in tif format of 2D mosaic of selected samples and 3D stacks in selected anatomical regions of interest. See readme file for more information.</p>
Confocal fluorescence microscopy images of the lacuno-canalicular network in bone femoral diaphysis of mice from the BionM1 project (space flight)
<p>This data set provides complementary measurements to a separate THG data set of the same study: doi: 10.5281/zenodo.1475906</p> <p>Data set for 1 sample of each of the 3 groups: Control, Space Flight and Synchro (ground control with space flight housing and feeding conditions). Contains confocal fluorescence microscopy images in tif format of 2D mosaic of selected samples and 3D stacks in selected anatomical regions of interest. See readme file for more information.</p>
Data from: State-space modelling of the flight behaviour of a soaring bird provides new insights to migratory strategies
1. Characterizing the spatiotemporal variation of animal behaviour can elucidate the way individuals interact with their environment and allocate energy. Increasing sophistication of tracking technologies paired with novel analytical approaches allows the characterisation of movement dynamics even when an individual is not directly observable. 2. In this study, high-resolution movement data collected via global positioning system (GPS) tracking in three dimensions were paired with topographical information and used in a Bayesian state-space model to describe the flight modes of migrating golden eagles (Aquila chrysaetos) in eastern North America. 3. Our model identified five functional behavioural states, two of which were previously undescribed variations on thermal soaring. The other states comprised gliding, perching and orographic soaring. States were discriminated by movement features in the horizontal (step length and turning angle) and vertical (change in altitude) planes, and by the association with ridgelines promoting wind deflection. Tracked eagles spent 2%, 31%, 38%, 9% and 20% of their day time in directed thermal soaring, gliding, convoluted thermal soaring, perching and orographic soaring, respectively. The analysis of the relative occurrence of these flight modes highlighted yearly, seasonal, age, individual and sex differences in flight strategy and performance. Particularly, less energy-efficient orographic soaring was more frequent in autumn, when thermals were less available. Adult birds were also better at optimising energy efficiency than sub-adults. 4. Our approach represents the first example of a state-space model for bird flight mode using altitude data in conjunction with horizontal locations, and is applicable to other flying organisms where similar data are available. The ability to describe animal movements in a three-dimensional habitat is critical to advance our understanding of the functional processes driving animals' decisions.
Space Flight Simulation to Study Effects of Micro-gravity Through Bed Rest
ClinicalTrials.gov study NCT00891449. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Data from: State-space modelling of the flight behaviour of a soaring bird provides new insights to migratory strategies
Open the record for dataset details and reuse information.
Data from: Cytoskeleton structure and total methylation of mouse cardiac and lung tissue during space flight
The purpose of this work was to evaluate the protein and mRNA expression levels of multiple cytoskeletal proteins in the cardiac and lung tissue of mice that were euthanized onboard the United States Orbital Segment of the International Space Station 37 days after the start of the SpaceX-4 mission (September 2014, USA). The results showed no changes in the cytoskeletal protein content in the cardiac and lung tissue of the mice, but there were significant changes in the mRNA expression levels of the associated genes, which may be due to an increase in total genome methylation. The mRNA expression levels of DNA methylases, the cytosine demethylases Tet1 and Tet3, histone acetylase and histone deacetylase did not change, and the mRNA expression level of cytosine demethylase Tet2 was significantly decreased.
Data from: Cytoskeleton structure and total methylation of mouse cardiac and lung tissue during space flight
Open the record for dataset details and reuse information.
The development of Drosophila melanogaster during space flight
In prospective human exploration of outer space the need to maintain a species over several generations under changed gravity conditions may arise. This paper reports the analysis of the third generation of fruit fly Drosophila melanogaster obtained during the 44.5-day space flight (Foton-M4 satellite 2014 Russia) followed by the fourth generation on Earth and the fifth generation under conditions of a 12-day space flight (2014 in the Russian Segment of the ISS). The obtained results show that it is possible to obtain the third-fifth generations of a complex multicellular Earth organism under changed gravity conditions (in the cycle weightlessness - Earth - weightlessness) which preserves fertility and normal development. However there were a number of changes in the expression levels and content of cytoskeletal proteins that are the key components of the spindle apparatus and the contractile ring of cells.
International Space Station flight project EXTREMOPHILES
The International Space Station (ISS) is a unique habitat for humans and microorganisms. Here, we report the results of the ISS experiment EXTREMOPHILES, including the analysis of microbial communities from several areas aboard at three time points. We assess microbial diversity, distribution, functional capacity and resistance profile using a combination of cultivation-independent analyses (amplicon and shot-gun sequencing) and cultivation-dependent analyses (physiological and genetic characterization of microbial isolates, antibiotic resistance tests, co-incubation experiments). We show that the ISS microbial communities are highly similar to those present in ground-based confined indoor environments and are subject to fluctuations, although a core microbiome persists over time and locations. The genomic and physiological features selected by ISS conditions do not appear to be directly relevant to human health, although adaptations towards biofilm formation and surface interactions were observed. Our results do not raise direct reason for concern with respect to crew health, but indicate a potential threat towards material integrity in moist areas.
RNA-Seq transcriptome analysis of reactive oxygen species gene network in Mizuna plants grown in long-term space flight
Space environment is suspected to generate reactive oxygen species (ROS) and induce oxidative stress in plants however little is known about the gene expression of ROS gene network in plants grown in long-term space flight. RNA-Seq was used to define the large-scale gene expression profiles of Mizuna harvested after 27 days cultivation in the international space station to understand the molecular response and adaptation to space environment.Results: Total reads of transcripts from the Mizuna grown in the international space station as well as on the ground by RNA-Seq using next generation sequencing technology showed 8,258 and 14,170 transcripts up- and down-regulated in the space-grown Mizuna respectively when compared with those from the ground-grown Mizuna. A total of 20 in 32 ROS oxidative marker genes were up-regulated including high expression of 4 hallmarks and preferentially expressed gene associated with ROS-scavenging genes was thioredoxin glutaredoxin and alternative oxidase genes. In the transcription factors of ROS gene network MEKK1-MKK4-MPK3 OXI1-MKK4-MPK3 and OXI1-MPK3 of MAP cascades induction of WRKY22 by MEKK1-MKK4-MPK3 cascade induction of WRKY25 and repression of ZAT7 by Zat12 were suggested. RbohD and RbohF genes were up-regulated preferentially in NADPH oxidase genes which produce ROS.Conclusions: Our large-scale transcriptome analysis demonstrated that the space environment induced oxidative stress and ROS gene network was activated in the space-grown Mizuna some of which were common genes up-regulated by abiotic and biotic stress and were preferentially up-regulated genes by the space environment even though Mizuna grew in the space as well as on the ground showing that plants could acclimate to the space environment by reprograming the expression of ROS gene network.
Salmonella Typhimurium transcription profiles in space flight
Salmonella transcription profiles were obtained from samples flown on space shuttle mission STS-115 and compared to profiles from Salmonella grown under identical conditions on the ground. Keywords: stress response transcriptional profile Triplicate experimental samples were hybridized to slides that contain three identical Salmonella ORF arrays. Each hybridization was performed with Cy3 labeled total RNA and Cy5 labeled gDNA as control.
In-Flight Human Skeletal Muscle Tissue Chip Autonomous Payload: Validation of Fiber Type and Metabolic Changes Due to Space Flight
GEO Series GSE234465. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide mapping of H3K27ac by Cut&Tag in CD4+ and CD8+ immune cells of astronauts following prolonged orbital space flight.
GEO Series GSE288469. Homo sapiens. 36 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Space flight mouse plasma cell-free RNA seuqnencing in Mouse Habitat Unit-1 (MHU-1)
GEO Series GSE213808. Mus musculus. 17 samples. Type: Expression profiling by high throughput sequencing.
50 Years of the First Manned Space Flight - Coin
50 years of the first manned space flight commemorative coin. 10 rubles. The diameter is 22 mm. Steel with brass plated coating. Made with 3DF Zephyr from 409 photos using CPL filter and polarized light for the mesh and 60 photos without filters for texture. Camera: Canon M10 with macro lense EF-M 28mm f/3.5 Macro IS STM. Normal map computed with Zephyr. Metalness and roughness maps converted from displacement map. Source: Objaverse 1.0 / Sketchfab
Neurocognitive Performance During Space Flight. Validation of a Test Battery
ClinicalTrials.gov study NCT02805400. IPD Sharing: NO. Countries: 1. Publications: 0.
Echocardiographic Assessment of Cardiovascular Changes in Long Term Space Flight
ClinicalTrials.gov study NCT00598598. IPD Sharing: NO. Countries: 1. Publications: 0.
IceBridge Sigma Space Lidar L0 Raw Time-of-Flight Data, Version 1
This data set contains raw time-of-flight measurements for Antarctica and Greenland acquired by the Sigma Space Lidar. The data were collected by scientists working on the Investigating the Cryospheric Evolution of the Central Antarctic Plate (ICECAP) project, which is funded by the National Science Foundation (NSF) and the Natural Environment Research Council (NERC), with additional support from NASA Operation IceBridge.
IceBridge Sigma Space Prototype L0 Raw Time-of-Flight Data, Version 1
This data set contains time-of-flight data captured over Antarctica using the Sigma Space Photon Counting Lidar Prototype instrument. The data were collected by scientists working on the Investigating the Cryospheric Evolution of the Central Antarctic Plate (ICECAP) project, which is funded by the National Science Foundation (NSF) and the Natural Environment Research Council (NERC), with additional support from NASA Operation IceBridge.
TOLNet NASA Goddard Space Flight Center Data
TOLNet_GSFC_Data is the lidar data collected by the Tropospheric Ozone (TROPOZ) lidar at the Goddard Space Flight Center (GSFC) as part of the Tropospheric Ozone Lidar Network (TOLNet). Data collection for this product is ongoing.In the troposphere, ozone is considered a pollutant and is important to understand due to its harmful effects on human health and vegetation. Tropospheric ozone is also significant for its impact on climate as a greenhouse gas. Operating since 2011, TOLNet is an interagency collaboration between NASA, NOAA, and the EPA designed to perform studies of air quality and atmospheric modeling as well as validation and interpretation of satellite observations. TOLNet is currently comprised of seven Differential Absorption Lidars (DIAL). Each of the lidars are unique, and some have had a long history of ozone observations prior to joining the network. Five lidars are mobile systems that can be deployed at remote locations to support field campaigns. This includes the Langley Mobile Ozone Lidar (LMOL) at NASA Langley Research Center (LaRC), the Tropospheric Ozone (TROPOZ) lidar at the Goddard Space Flight Center (GSFC), the Tunable Optical Profile for Aerosol and oZone (TOPAZ) lidar at the NOAA Chemical Sciences Laboratory (CSL) in Boulder, Colorado, the Autonomous Mobile Ozone LIDAR instrument for Tropospheric Experiments (AMOLITE) lidar at Environment and Climate Change Canada (ECCC) in Toronto, Canada, and the Rocket-city O3 Quality Evaluation in the Troposphere (RO3QET) lidar at the University of Alabama in Huntsville, Alabama. The remaining lidars, the Table Mountain Facility (TMF) tropospheric ozone lidar system located at the NASA Jet Propulsion Laboratory (JPL), and City College of New York (CCNY) New York Tropospheric Ozone Lidar System (NYTOLS) are fixed systems.TOLNet seeks to address three science objectives. The primary objective of the network is to provide high spatio-temporal measurements of ozone from near the surface to the top of the troposphere. Detailed observations of ozone structure allow science teams and the modeling community to better understand ozone in the lower-atmosphere and to assess the accuracy and vertical resolution with which geosynchronous instruments could retrieve the observed laminar ozone structures. Another objective of TOLNet is to identify an ozone lidar instrument design that would be suitable to address the needs of NASA, NOAA, and EPA air quality scientists who express a desire for these ozone profiles. The third objective of TOLNET is to perform basic scientific research into the processes create and destroy the ubiquitously observed ozone laminae and other ozone features in the troposphere. To help fulfill these objectives, lidars that are a part of TOLNet have been deployed to support nearly ten campaigns thus far. This includes campaigns such as the Deriving Information on Surface conditions from Column and Vertically Resolved Observations Relevant to Air Quality (DISCOVER-AQ) mission, the Korea United States Air Quality Study (KORUS-AQ), the Tracking Aerosol Convection ExpeRiment – Air Quality (TRACER-AQ) campaign, the Front Range Air Pollution and Photochemistry Éxperiment (FRAPPÉ), the Long Island Sound Tropospheric Ozone Study (LISTOS), and the Ozone Water–Land Environmental Transition Study (OWLETS).
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.