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26 results for “sperm activation”
A test for plasticity in sperm motility activation
<p>Evolutionary theory predicts that selection will favour phenotypic plasticity in sperm traits that maximise fertilisation success in dynamic fertilisation environments. In species with external fertilisation, osmolality of the fertilisation medium is known to play a critical role in activating sperm motility, but evidence for osmotic-induced sperm plasticity is limited to euryhaline fish and marine invertebrates. Whether this capacity extends to freshwater taxa remains unknown. Here, we provide the first test for plasticity in sperm-motility activation in response to osmotic environment in an anuran amphibian. Unexpectedly, there was no detectable shift in the optimal osmolality for sperm-motility activation after approximately 13 weeks of acclimation (a period reflecting the duration of the winter breeding season). However, in both the low and high acclimation treatments, the optimal osmolality for sperm-motility activation mirrored the osmolality at the natural breeding site, indicating a phenotypic match to the local environment. Previously it has been shown that <em>C. signifera</em> display among-population covariation between environmental osmolality and sperm performance. Coupled with this finding, the results of the present study suggest that inter-population differences reflect genetic divergence and local adaptation. We discuss the need for experimental tests of osmotic-induced sperm plasticity in more freshwater taxa to better understand the environmental and evolutionary contexts favouring adaptive plasticity in sperm-motility activation.</p>
A test for plasticity in sperm motility activation
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Data from: Salinity-induced phenotypic plasticity in threespine stickleback sperm activation
Phenotypic expression may be and often is influenced by an organism's developmental environment, referred to as phenotypic plasticity. The sperm cells of teleosts have been found to be inactive in the seminal plasma and are activated by osmotic shock for most fish species, through release in either hypertonic (for marine fish) or hypotonic (for freshwater fish) water. If this is the case, the regulatory system of sperm mobility should be reversed in salt and freshwater fish. We tested this hypothesis by first activating sperm of saltwater and freshwater populations of threespine stickleback in salt- and fresh water. The sperm from saltwater stickleback could be activated in either salinity, which matches the freshwater colonization history of the species, whereas the sperm from the freshwater population acted as predicted by the osmotic shock theory and was activated in freshwater only. As the freshwater population used here was calculated to be thousands of years old, we went on to test whether the trait(s) were plastic and sperm from freshwater males still could be activated in saltwater after individuals were exposed to saltwater. After raising freshwater stickleback in saltwater we found the mature males to have active sperm in both salt and freshwater. Further, we also found the sperm of wild-caught freshwater stickleback to be active in saltwater after exposing those mature males to saltwater for only two days. This illustrates that the ability for stickleback sperm to be activated in a range of water qualities is an environmentally induced plastic trait.
Improving sperm quality of large South American catfish using trehalose-based activating solutions
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Sperms Activation by Direct Electrical Shocks on Testis in Infertile Males
ClinicalTrials.gov study NCT04173052. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Data from: Salinity-induced phenotypic plasticity in threespine stickleback sperm activation
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Avian zygote activates only maternal allele to disburden high variation of supernumerary sperms contrary to mammal
GEO Series GSE100798. Gallus gallus. 9 samples. Type: Expression profiling by high throughput sequencing.
Sperm-derived circRNA-1572 regulates embryogenesis and zygotic genome activation by targeting CCNB2 via bta-miR-2478-L-2 [ncRNA-seq]
GEO Series GSE288539. Sus scrofa. 9 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Sperm heterogeneity and DNMT/TET activities do not account for sperm DNA methylation changes observed in the epididymis
GEO Series GSE191051. Mus musculus. 12 samples. Type: Methylation profiling by high throughput sequencing.
TET1 catalytic activity is required for reprogrammign of imprinting control regions and the patterning of sperm-specific hypomethylated regions
GEO Series GSE224459. Mus musculus. 63 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by genome tiling array.
Sperm-derived circRNA-1572 regulates embryogenesis and zygotic genome activation by targeting CCNB2 via bta-miR-2478-L-2 [SMART-seq]
GEO Series GSE288540. Sus scrofa. 12 samples. Type: Expression profiling by high throughput sequencing.
The effect of ionomycin-induced oocyte activation on multiple morphological abnormalities of the sperm flagella
GEO Series GSE216618. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Sperm-derived circRNA-1572 regulates embryogenesis and zygotic genome activation by targeting CCNB2 via bta-miR-2478-L-2 [miRNA-seq]
GEO Series GSE288538. Sus scrofa. 9 samples. Type: Non-coding RNA profiling by high throughput sequencing.
TET1 catalytic activity is required for reprogrammign of imprinting control regions and the patterning of sperm-specific hypomethylated regions [Mouse Methylation285 12v1-0 BeadChip]
GEO Series GSE224349. Mus musculus. 36 samples. Type: Methylation profiling by genome tiling array.
Novel Approach With Double Agent Artificial Oocyte Activation for Repeated Fertilization Failure Due to Combined Sperm and Oocyte Factor
ClinicalTrials.gov study NCT02418416. IPD Sharing: Not stated. Countries: 2. Publications: 0.
Fertilizations With Immotile Sperm: Pentoxyphylline Activation Alone, or With Chemical Oocyte Activation
ClinicalTrials.gov study NCT02051075. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Using of Testes Shocker in Improving the Spermatogenesis and Sperms Activity
ClinicalTrials.gov study NCT05506722. IPD Sharing: NO. Countries: 1. Publications: 0.
The Impact of Lifestyle on Sperm Telomere Length and Telomerase Activity in Men Undergoing IVF Treatments
ClinicalTrials.gov study NCT04158765. IPD Sharing: NO. Countries: 1. Publications: 0.
Magnetic Activated Cell Sorting in Artificial Insemination With Donor Sperm
ClinicalTrials.gov study NCT03659812. IPD Sharing: Not stated. Countries: 1. Publications: 0.
To Study the Effect of Magnetic Activated Sperm Sorting on the Outcome of in Vitro Fertilization-embryo Transplantation
ClinicalTrials.gov study NCT03968367. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.