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209 results for “stress evaluation”
Outdoor mesocosm study evaluating how mass, NaCl tolerance, and pesticide tolerance affect oxidative stress biomarkers (CAT, SOD, GR, GPx, TBARS) in larval wood frogs (Rana sylvatica) exposed to baseline and NaCl-contaminated conditions, 2019
Biomarkers of oxidative stress can aid in wildlife monitoring by allowing conservationists to detect sublethal environmental shifts. However, interpretation of stress responses can be complicated by multiple interacting factors (e.g., individual development, evolved physiological tolerance to stressors) which alter biomarker expression. Here, we investigated how individual ontogenetic traits and population-level tolerance traits influence oxidative stress responses under baseline and contaminated environmental conditions. For our model contaminant, we used NaCl (common freshwater contaminant due to factors such as coastal flooding, irrigation, airborne salt circulation, drought, runoff from road deicing salts). For our model wildlife populations, we used larval wood frogs (Rana sylvatica) from six noninteracting populations known to vary in two population-level tolerance traits: NaCl tolerance (calculated as average time to death from lethal NaCl exposure) and pesticide tolerance (determined by proxy of distance to agriculture - a consistent and highly repeatable relationship). At an outdoor research facility, R. sylvatica tadpoles were exposed to either baseline conditions (0 g/L NaCl added) or NaCl-contaminated conditions (1 g/L NaCl added for 21 days, then reduced to 0.5 g/L NaCl). Exposures were conducted in individual units with 40 replicates per population for each treatment. The experiment was terminated per individual to capture the full term of larval development (Developmental stage: Gosner stage 36), lasting between 33-48 days. For each individual, we measured mass, Snout-Vent-Length, and developmental stage before processing for biomarker expression. Individual homogenates were assayed for oxidative stress biomarkers superoxide dismutase (SOD; responsible for Reactive Oxygen Species capture and peroxide production), glutathione peroxidase (GPx; responsible for high-affinity peroxide reduction), catalase (CAT; responsible for low-affinity peroxide reducti
Figure 4 in Evaluation of nickel-induced brain injuries in rats via oxidative stress and apoptosis: attenuating effects of hyperoside
Figure 4. Morphology and location of PAS granules of brain tissues of control (A), Hyp-treated (B), Ni-treated (C), and Ni + Hyp-treated (D) rats. Homogeneous PAS staining was observed in the control group (A) and the Hyp-treated (B) groups. Clusters of granules shown inside square (C) and by black arrow (D), respectively (200× magnification).
Figure 3 in Evaluation of nickel-induced brain injuries in rats via oxidative stress and apoptosis: attenuating effects of hyperoside
Figure 3. Histological views of brain tissues of control (A), Hyp-treated (B), Ni-treated (C), and Ni + Hyp-treated (D) rats. Small blood vessels (BV) from pia mater penetrate the cerebral cortex substance pyramidal cells (PC) with apical dendrites closely associated with smaller, round glial cells (GC) (A and B). Perivascular inflammation around a blood vessel (inside square) (C) and perivascular inflammatory cell infiltrates in hematoxylin and eosin-stained brain tissue (D) (200× magnification).
Figure 5 in Evaluation of nickel-induced brain injuries in rats via oxidative stress and apoptosis: attenuating effects of hyperoside
Figure 5. Brain tissues of control (A) and Hyp (B) groups were negative for Congo red. Amyloid deposits in brain parenchyma and around blood vessels shown inside square (C) and marked by black arrows (D) (200× magnification). Differences in measured parameters among the groups were analyzed with a nonparametric test (Kruskal–Wallis). Dual comparisons between groups exhibiting significant values were evaluated with a Mann–Whitney U test (P <0.05).
Figure 1 in Evaluation of nickel-induced brain injuries in rats via oxidative stress and apoptosis: attenuating effects of hyperoside
Figure 1. Effect of Ni administration on body weight gain. Data are presented as mean ± standard error of mean (SEM) (n = 7). a Significant differences between other studied groups and control (a4 P <0.0001). b Significant differences between other groups studied and Hyp group (b1 P <0.05, b4 P <0.0001). c Significant differences between other groups studied and Ni + Hyp group (c3 P <0.001) by Tukey's multiple range tests.
Dataset: A quantitative 1H NMR approach for evaluating the metabolic response of Saccharomyces cerevisiae to mild heat stress
<p>In this study, the effect of growth temperature on the yeast (<em>Saccharomyces cerevisiae</em>) metabolome has been analyzed by one-dimensional proton NMR spectroscopy (<sup>1</sup>H NMR).</p> <p>Yeast cells were grown either at 30 or 37°C. A non-targeted chemometric evaluation of the spectra was performed in order to detect potential biomarkers. Moreover, an exhaustive assignment for most of the detected NMR signals was carried out, corresponding to 38 identified metabolites. Resonances from these identified metabolites were integrated, and univariate and multivariate data analyses were applied on the matrices of these relative concentrations. Observed changes in metabolite concentrations were consistent with the expected process of temperature acclimation, showing alterations in amino acid cellular pools, nucleotide metabolism and lipid composition.</p>
Evaluation of oxidative stress markers in Rwanda during the SARS-CoV-2 pandemic: a cross-sectional study
<p>SARS-CoV-2 is mainly described as endothelial dysfunction, and due to the bidirectional link between oxidative stress and endothelial dysfunction, we initiated a program directed to the evaluation of the oxidative status of the population of Rwanda by measuring spectrophotometrically their plasma Reactive Oxygen Metabolites (dROMs) and Plasma Antioxidant Potential (PAT). The reference population was chosen to reflect the absence of actual or past SARS-CoV-2 infections as well as other clinically established infective status and reference intervals for d-ROM and PAT were identified.</p> <p>The average d-ROM was 378.6 UCARR with a standard deviation of 105.2. The average PAT value was 2853.6, with a standard deviation of 635.7 UCOR. On the basis of the published values for the Caucasian and East Asian populations, the average value of d-ROM obtained in Rwanda was significantly higher than expected. Conversely, the average PAT value was at the upper limit according to the averaged values for healthy Caucasian populations. The results of this study, the first so far reported on a sub-Saharan population, can effectively be used as a baseline value for clinical management of inflammatory conditions, for the stratification of at-risk individuals and to inform recommendations for effective use of public health resources.</p>
Evaluation of The Effects of Nebivolol in Comparison to Atenolol on Wall Shear Stress and Rupture Prone Coronary Plaques
ClinicalTrials.gov study NCT01230892. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Evaluation of GSK561679 in Women With Post-Traumatic Stress Disorder
ClinicalTrials.gov study NCT01018992. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Evaluating the Change of Overactive Bladder Symptoms in Women Post Pubovaginal Sling Procedure for Stress Incontinence
ClinicalTrials.gov study NCT01194999. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Stress Cardiac MRI for Evaluation of Nonspecific Allograft Dysfunction
ClinicalTrials.gov study NCT02597543. IPD Sharing: Not stated. Countries: 1. Publications: 12.
A Study Evaluating Sleep, Stress and Infant Nutrition Using a Chatbot
ClinicalTrials.gov study NCT03630679. IPD Sharing: NO. Countries: 1. Publications: 1.
Evaluation of Integrated Optimization Schemes for Female Stress Incontinence
ClinicalTrials.gov study NCT05053373. IPD Sharing: YES. Countries: 1. Publications: 23.
Evaluation Of The Ability Of Fesoterodine To Increase Urethral Pressure In Stress Urinary Incontinence Patients
ClinicalTrials.gov study NCT01042236. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Data from: Exploratory study evaluating the relationships between perinatal adversity, oxidative stress, and infant neurodevelopment across the first year of life data
Open the record for dataset details and reuse information.
Evaluation of oxidative stress markers in Rwanda during the SARS-CoV-2 pandemic: a cross-sectional study
Open the record for dataset details and reuse information.
Increased sediment load destabilize algal turf at two different fringing reefs; Evaluating responses across a stress gradient, Moorea, French Polynesia, 2016
Seven reefs in Moorea French Polynesia were examined for sediment and turf characteristics to establish a baseline for naturally occurring proportions of sediment within the turf matrix. At each of the seven sites turf filament heights and sediment depths within the turf matrix were measured using a galvanized mesh measuring device calibrated by 1mm increments. All surveys were conducted between 2-3m in depth between April-May of 2016. We then conducted a two-factor experiment where sediment depth was manipulated at two sites surveyed with strong differences in turf communities (Maharepa and Gump). Our experiment ran for 30 days, with sediment treatments maintained every four days.
Dataset related to publication "In silico evaluation of the thermal stress induced by MRI switched gradient fields in patients with metallic hip implant"
<p>The datasets reported in the figures of the article "In silico evaluation of the thermal stress induced by MRI switched gradient fields in patients with metallic hip implant", published on Phys. Med. Biol. 64 245006, 2019.</p> <p>This work focuses on the in silico evaluation of the energy deposed by MRI switched gradient fields<br> in bulk metallic implants and the consequent temperature increase in the surrounding tissues. The results show that the gradient coils can generate local increases of temperature up to some kelvin when acting without radiofrequency excitation. Hence, their contribution in general should not be disregarded when evaluating patients’ safety.</p>
Data from: Experimental evaluation of the robustness of the growth-stress tolerance trade-off within the perennial grass Dactylis glomerata
1. A core tenet of functional ecology is that the vast phenotypic diversity observed in the plant kingdom could be partly generated by a trade- off between the ability of plants to grow quickly and acquire resources in rich environments vs. the ability to conserve resources and avoid mortality under stress. However, experimental demonstrations remain scarce and potentially blurred by phylogenetic constraints in cross-species analyses. Here we experimentally decoupled growth potential and stress survival by applying an off-season stress on contrasting populations of the perennial grass Dactylis glomerata exhibiting a range of seasonal dormancy. 2. Seventeen populations of D. glomerata, originating from a latitudinal gradient from Norway to Morocco, were subjected to three types of dehydration stress: winter frost in Norway, summer drought, and early spring (off-season) drought stress in the south of France. Growth rate, and two leaf traits (leaf width and leaf dry matter content) suspected to be involved in the adaptation to dehydration stress, were monitored under optimal conditions. We quantified plant dehydration survival as the amount of plant recovery after a severe stress. 3. Nordic populations were found to be winter dormant. Winter and summer dormant populations better survived frost and summer drought, respectively. However, no trade-off between growth potential and dehydration survival was detected in non-dormant plants in early spring when dehydration occurred unseasonably for all populations. Furthermore, Mediterranean populations better survived an early spring drought. 4. Our results highlight the importance of assessing plant growth potential as a response to seasonal environmental cues. They suggest that growth potential and stress survival trade-off when plants exhibit seasonal dormancy but can be functionally independent at other seasons. Consequently, the growth-stress survival relationship could be better described as a dynamic linkage rather than a constant and general trade-off. Moreover, leaf trait values, such as thinner and more lignified leaves reflecting drought adaptation, may have contributed to the improved drought-stress survival without resulting in a cost to growth. 5. Further exploration of the growth-stress survival relationship should permit deciphering the suite of plant traits and trait covariations involved in plants' responses to increasing stress.
Benchmark for EvaluaTing BCI Reliability Under STress (BETRUST)
<pre>This dataset comprises the data and corresponding labels used for assessing model reliability of Brain-computer Interfaces(BCI).</pre>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.