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155 results for “stress interactions”
The interactive effects of predator stress, predation, and the herbicide Roundup®
These data are from a mesocosm experiment examined how lethal predators and cues from caged predators potentially interacted with four concentrations of the herbicide Roundup® in its effects on three species of tadpoles (gray tree frogs, green frogs, bulfrogs).
Data from: The interactive effects of heat stress, parasitism, and hostplant quality in a host-parasitoid system
<p>Species interactions are expected to change in myriad ways as the frequency and magnitude of extreme temperature events increase with anthropogenic climate change. The relationships between endosymbionts, parasites, and their hosts are particularly sensitive to thermal stress, which can have cascading effects to other trophic levels. We investigate the interactive effects of heat stress and parasitism on a terrestrial tritrophic system consisting of two hostplants (one common, high-quality plant and one novel, low-quality plant), a caterpillar herbivore, and a specialist parasitoid wasp. We used a fully-factorial experiment to determine the bottom-up effects of the novel hostplant on both the caterpillars' life history traits and the wasps' survival, and the top-down effects of parasitism and heat shock on caterpillar developmental outcomes and herbivory levels. Hostplant identity interacted with thermal stress to affect wasp success, with wasps performing better on the low-quality hostplant under constant temperatures but worse under heat shock conditions. Surprisingly, caterpillars consumed less leaf material of the low-quality hostplant to reach the same final mass across developmental outcomes. In parasitized caterpillars, heat shock reduced parasitoid survival and increased both caterpillar final mass and development time on both hostplants. These findings highlight the importance of studying community-level responses to climate change from a holistic and integrative perspective and provide insight into potential substantial interactions between thermal stress and diet quality in plant-insect systems.</p>
Interactive map of Heat Stress Compensability Classification (HSCC) application in 96 United States cities.
<p>This repository includes the interactive map in format .html of the very first application of the <strong>Heat Stress Compensability Classification (HSCC) in 96 cities in the United States </strong>showing the proportion of days with compensable and uncompensable heat stress from the top 10th percentile of hottest days from 2005-2020 in each place.</p> <p>This map offers the detailed results of the very first application of the classification system as in the journal article: <strong>The Development of an Adaptive Heat Stress Compensability Classification Applied to the United States</strong>, published in the 4th SNP special issue in the International Journal of Biometeorology. The results of this visualization were obtained from open-source data and coding packages such as Folium, and the model results were obtained by applying the Python Human Heat Balance (PyHHB) on weather dataset freely available.</p> <p>The interactive map offers a detailed visualization of the results from each of the cities, allowing you to see 3 tabs when the icon of the pie chart from each location is clicked.</p> <p><strong>Tab statistics:</strong> Detail per city of Figure 4b of related paper.</p> <p><strong>Tab Histogram 2D: </strong>Details per city of Fig 6 of related paper</p> <p><strong>Tab How to read: </strong>Figure 2 in related paper.</p> <p>Please for questions related to this dataset/code contact Gisel Guzman-Echavarria (gguzma20@asu.edu).</p> <p>Guzman-Echavarria, G., & Vanos, J. (2023). PyHHB: Physiological-based estimations of human survivability and liveability to heat in a changing climate (Nature Communications (1.0.0)). Zenodo. https://doi.org/10.5281/zenodo.10020137</p> <p> </p> <p> </p>
The proteasome-interacting Ecm29 protein disassembles the 26S proteasome in response to oxidative stress
<p>This repository contains the modeling files and the analysis related to the article <a href="https://www.ncbi.nlm.nih.gov/pubmed/28821611">"The proteasome-interacting Ecm29 protein disassembles the 26S proteasome in response to oxidative stress"</a> by Wang et al. in J Biol Chem 2017.</p> <p><strong>For more information</strong> about how to reproduce this modeling, see the <a href="https://salilab.org/ecm29/">Sali lab website</a> or the README file.</p>
Interactive effects of immediate and ancestral salt stress on fitness in duckweed
<p><em>Premise of Research</em></p> <p>Organisms that reproduce asexually must respond to abiotic stresses in their environment while contending with the potential disadvantage of the reduced ability for genetic variation through recombination. Common duckweed (<em>Lemna minor</em>) is an aquatic plant that reproduces predominantly asexually through the budding of ramets. As a freshwater plant, duckweed experiences stress from salt (e.g., NaCl), which detrimentally affects growth, photosynthesis, and cellular processes. We took a demographic approach to examine whether ancestral exposure to salt stress affects the ability of duckweed offspring to tolerate immediate exposure to the same stress.</p> <p><em>Methodology</em></p> <p>We placed three consecutive clonal generations of duckweed in an environment with 2 g L<sup>-1</sup> NaCl (non-lethal salt stress) or 0 g L<sup>-1</sup> NaCl (control), followed by an additional 0-3 generations in the control environment to vary the presence and schedule of ancestral stress. After these treatments, we used the offspring produced as focal plants for the experiment. Half were placed into the salt-stress environment, and half were placed in control conditions, and focal plants were tracked longitudinally.</p> <p><em>Pivotal Results</em></p> <p>Immediate stress decreased fitness, due to a slowing of reproduction, suggesting a cost of stress tolerance. The effects of ancestral stress, and the interaction of immediate and ancestral stress, were more complex. Specifically, recent ancestral stress induced plants to produce offspring more quickly, but with the potential cost of lowered offspring quality.</p> <p><em>Conclusions</em></p> <p>Our results amplify findings that responses to, and fitness consequences of, current stressors can be contingent on past exposure.</p>
Host-pathogen interactions under pressure: a review and meta-analysis of stress-mediated effects on disease dynamics
<p>Human activities have increased the intensity and frequency of natural stressors and created novel stressors, altering host-pathogen interactions, and changing the risk of emerging infectious diseases. Despite the ubiquity of such anthropogenic impacts, predicting the directionality of outcomes has proven challenging. Here, we conduct a review and meta-analysis to determine the primary mechanisms through which stressors affect host-pathogen interactions and to evaluate the impacts stress has on host fitness (survival and fecundity) and pathogen infectivity (prevalence and intensity). We assessed 891 effect sizes from 71 host species (representing seven taxonomic groups) and 78 parasite taxa from 98 studies. We found that infected and uninfected hosts had similar sensitivity to stressors and that responses varied according to stressor type. Specifically, limited resources compromised host fecundity and decreased pathogen intensity, while abiotic environmental stressors (e.g., temperature and salinity) decreased host survivorship and increased pathogen intensity, and pollution increased mortality but decreased pathogen prevalence. We then used our meta-analysis results to develop Susceptible-Infected theoretical models to illustrate scenarios where infection rates are expected to increase or decrease in response to resource limitation or environmental stress gradients. Our results carry implications for conservation and disease emergence and reveal areas for future work. </p>
Data from: The interactive effects of heat stress, parasitism, and hostplant quality in a host-parasitoid system
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Interactive effects of immediate and ancestral salt stress on fitness in duckweed
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Host-pathogen interactions under pressure: a review and meta-analysis of stress-mediated effects on disease dynamics
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SGS-LTER Ecosystem Stress Area - Aboveground Biomass: Interactions between individual plant species and soil nutrient status in shortgrass steppe on the Central Plains Experimental Range in Nunn, Colorado, USA 1991
This data package was produced by researchers working on the Shortgrass Steppe Long Term Ecological Research (SGS-LTER) Project, administered at Colorado State University. Long-term datasets and background information (proposals, reports, photographs, etc.) on the SGS-LTER project are contained in a comprehensive project collection within the Digital Collections of Colorado (http://digitool.library.colostate.edu/R/?func=collections&collection_id=3429). The data table and associated metadata document, which is generated in Ecological Metadata Language, may be available through other repositories serving the ecological research community and represent components of the larger SGS-LTER project collection. The effect of plant community structure on nutrient cycling is fundamental to our understanding of ecosystem function. We examined the importance of plant species and plant cover (i.e. plant covered microsites vs bare soil) on nutrient cycling in shortgrass steppe of northeastern Colorado. We tested the effects of both plant species and cover on soils in an area of undisturbed shortgrass steppe and an area that had undergone nitrogen and water additions from 1971 to 1974, resulting in significant shifts in plant species composition.
SGS-LTER Ecosystem Stress Area - Belowground Biomass: Interactions between individual plant species and soil nutrient status in shortgrass steppe on the Central Plains Experimental Range in Nunn, Colorado, USA 1991
This data package was produced by researchers working on the Shortgrass Steppe Long Term Ecological Research (SGS-LTER) Project, administered at Colorado State University. Long-term datasets and background information (proposals, reports, photographs, etc.) on the SGS-LTER project are contained in a comprehensive project collection within the Digital Collections of Colorado (http://digitool.library.colostate.edu/R/?func=collections&collection_id=3429). The data table and associated metadata document, which is generated in Ecological Metadata Language, may be available through other repositories serving the ecological research community and represent components of the larger SGS-LTER project collection. The effect of plant community structure on nutrient cycling is fundamental to our understanding of ecosystem function. We examined the importance of plant species and plant cover (i.e. plant covered microsites vs bare soil) on nutrient cycling in shortgrass steppe of northeastern Colorado. We tested the effects of both plant species and cover on soils in an area of undisturbed shortgrass steppe and an area that had undergone nitrogen and water additions from 1971 to 1974, resulting in significant shifts in plant species composition. Additional information and referenced materials can be found: http://hdl.handle.net/10217/83317.
Data from: Achromatic plumage brightness predicts stress resilience and social interactions in tree swallows (Tachycineta bicolor)
Theory suggests that signal honesty may be maintained by differential costs for high and low quality individuals. For signals that mediate social interactions, costs can arise from the way that a signal changes the subsequent social environment via receiver responses. These receiver-dependent costs may be linked with individual quality through variation in resilience to environmental and social stress. Here, we imposed stressful conditions on female tree swallows (Tachycineta bicolor) by attaching groups of feathers during incubation to decrease flight efficiency and maneuverability. We simultaneously monitored social interactions using an RFID network that allowed us to track the identity of every individual that visited each nest for the entire season. Prior to treatments, plumage coloration was correlated with baseline and stress-induced corticosterone. Relative to controls, experimentally challenged females were more likely to abandon their nest during incubation. Overall, females with brighter white breasts were less likely to abandon, but this pattern was only significant under stressful conditions. In addition to being more resilient, brighter females received more unique visitors at their nest box and tended to make more visits to other active nests. In contrast, dorsal coloration did not reliably predict abandonment or social interactions. Taken together, our results suggest that females differ in their resilience to stress and that these differences are signaled by plumage brightness, which is in turn correlated with the frequency of social interactions. While we do not document direct costs of social interaction, our results are consistent with models of signal honesty based on receiver-dependent costs.
ROS-specific Huntingtin Interactions: Oxidative Stress Optimization H2O2
<p>Optimization step in the lead up to mass spec identification of ROS-specific huntingtin protein-protein interactions.</p>
Rheological structure and lithospheric stress interaction in the Alaska subduction zone gleaned from the 2018 Mw 7.9 oceanic crustal earthquake
<p>This repository contains the observed and modeled first 2-year timeseries of postseismic deformation at GPS sites in the best-fit model associated with the 2018 Mw 7.9 Kodiak, Alaska earthquake (Timeseries.rar), as well as the preferred afterslip on the fault (Afterslip.rar).</p>
Data from: Physiological effects of interacting native and invasive bivalves under thermal stress
<p>Across many ecosystems in North America and Europe, native freshwater bivalves (Order Unionida) are threatened by fouling and competition for food by the invasive zebra mussel <em>Dreissena polymorpha</em>. In light of climate change, knowledge on the influence of water temperature on these competitive effects is important, yet poorly understood. This study examines the physiological impact of the interaction between <em>D. polymorpha</em> and the native European unionid <em>Anodonta cygnea</em> over a 28-day period in response to water temperatures of 12, 19, and 25 °C by comparing their glycogen, glucose, lipid, and protein concentrations. The laboratory experiment comprised three treatments: (1) fouling of <em>A. cygnea</em> by <em>D. polymorpha</em>, (2) both species present but not fouling; and (3) a control in which <em>A. cygnea</em> and <em>D.</em> <em>polymorpha</em> were placed separately. Increased water temperatures caused physiological stress in <em>D. polymorpha</em> as evident from reduced glycogen, glucose, lipid, and protein concentrations. <em>Dreissena polymorpha</em> benefited from fouling of unionids, as individuals that fouled <em>A. cygnea</em> tended to have increased glycogen, glucose, lipid and protein concentrations. Competitive effects of <em>D. polymorpha</em> over the unionid bivalve species, however, were not intensified by elevated temperatures. Glochidia release, lower infestation intensity, and physiological stress of <em>Dreissena </em>at higher temperatures were likely confounding factors. The results of this study suggest that understanding the physiological consequences of species interactions at changing temperatures can be an important tool to assess future climate change impacts on freshwater bivalves and aquatic community structures.</p>
Positive interactions between corals and damselfish increase coral resistance to temperature stress
<p>By the century's end, many tropical seas will reach temperatures exceeding most coral species' thermal tolerance on an annual basis. The persistence of corals in these regions will therefore depend on their abilities to tolerate recurrent thermal stress. Although ecologists have long recognized that positive interspecific interactions can ameliorate environmental stress to expand the realized niche of plants and animals, coral bleaching studies have largely overlooked how interactions with community members outside of the coral holobiont shape the bleaching response. Here, we subjected a common coral, <em>Pocillopora</em> <em>grandis</em>, to 10 days of thermal stress in aquaria with- and without the damselfish <em>Dascyllus</em> <em>flavicaudus</em> (yellowtail dascyllus), which commonly shelter within these corals, to examine how interactions with damselfish impacted coral thermal tolerance. Corals often benefit from nutrients excreted by animals they interact with and prior to thermal stress, corals grown with damselfish showed improved photophysiology (F<sub>v</sub>/F<sub>m</sub>) and developed larger endosymbiont populations. When exposed to thermal stress, corals with fish performed as well as corals maintained at ambient temperatures without fish. In contrast, corals exposed to thermal stress without fish experienced photophysiological impairment, a more than 50% decline in endosymbiont density, and a 36% decrease in tissue protein content. By the end of the experiment, thermal stress caused average calcification rates to decrease by over 80% when damselfish were absent but increase nearly 25% when damselfish were present. Our study indicates that damselfish-derived nutrients can increase coral thermal tolerance and are consistent with the Stress Gradient Hypothesis, which predicts that positive interactions become increasingly important for structuring communities as environmental stress increases. Because warming of just a few degrees can exceed corals' temperature tolerance to trigger bleaching and mortality, positive interactions could play a critical role in maintaining some coral species in warming regions until climate change is aggressively addressed.</p>
Interactions between phenanthrene exposure and historical chemical stress: Implications for fitness and ecological resilience of the sentinel species Daphnia magna
<div> <p>Polycyclic aromatic hydrocarbons (PAHs) arise from incomplete combustion of oil, coal, and gasoline, with lipophilic properties facilitating their widespread distribution and persistence. Due to their biochemical attributes, PAHs can accumulate in animal tissues, potentially causing mutagenic and carcinogenic effects. Since the industrial revolution, PAH concentrations in the environment have risen, with some areas showing levels from 0.159 to 33,090 µg/kg sediment. Despite acute toxicity studies showing adverse effects on freshwater organisms, the long-term impacts and synergistic interactions with other pollutants remain largely unexplored. </p> </div> <div> <p>This study investigates the impact of phenanthrene (PHE), a prominent PAH found in aquatic environments, on <em>Daphnia magna</em>, a species of significant ecological importance in freshwater ecosystems globally, being both a sentinel species for chemical pollution and a keystone organism in freshwater aquatic ecosystems. Leveraging the dormancy of <em>D. magna</em>, which spans decades or even centuries, we exposed strains with diverse histories of chemical contaminant exposure to environmentally relevant concentrations of PHE. Initially, acute exposure experiments were conducted in accordance with OECD guidelines across 16 <em>Daphnia</em> strains, revealing substantial variation in acute toxic responses, with strains naïve to chemical pollutants showing the lowest toxicity. Utilizing the median effect concentration EC10 derived from acute exposures, we assessed the impacts of chronic PHE exposure on the life history traits and ecological endpoints of the 16 strains. To elucidate how historical exposure to other environmental stressors may modulate the toxicity of PHE, temporal populations of <em>D. magna</em> resurrected from a lake with a well-documented century-spanning history of environmental impact were utilized. Our findings demonstrate that PHE exposure induces developmental failure, delays sexual maturation, and reduces adult size in <em>Daphnia</em>. Populations of <em>Daphnia</em> historically exposed to chemical stress exhibited significantly greater fitness impacts compared to naïve populations. This study provides crucial insights into the augmented effects of PAHs interacting with other environmental stressors. </p> </div>
Interactive effects of ZnO nanoparticles and temperature on molecular and cellular stress responses of the blue mussel Mytilus edulis
<p>We investigate the molecular and cellular stress responses of tissues (gills and digestive glands) in the mussels <em>Mytilus edulis </em>exposed for 21 days to either ambient (10 °C in winter and 15 °C in summer) or elevated (by 5 °C) temperature combined with different concentrations (0, 10, 100 µg l<sup>-1</sup>) of ZnO nanoparticles or dissolved zinc. In this data set, we used a biomarker-based approach focusing on oxidative stress indicators ( lipid peroxidation and protein carbonyls) and transcription pattern of marker genes in the pathways related to cell survival and proliferation (caspase 3, Bcl-2, p53, p38 and JNK) and inflammation (COX, NF-κB, and TGF-β) of <em>M. edulis</em>. </p>
Cytoscape files - Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation
<p>Cytoscape files of pathway enrichment analyses and PPI mapping associated with manuscript https://www.nature.com/articles/s41467-023-39241-7</p> <p><strong>Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics</strong> <strong>identify cancer-specific mechanisms of stress adaptation </strong></p> <p>Anna Rodina<sup>1,11</sup>, Chao Xu<sup>1,11</sup>, Chander S. Digwal<sup>1,11</sup>, Suhasini Joshi<sup>1,11</sup>, Anand R. Santhaseela<sup>1</sup>, Sadik Bay<sup>1</sup>, Swathi Merugu<sup>1</sup>, Aftab Alam<sup>1</sup>, Pengrong Yan<sup>1</sup>, Chenghua Yang<sup>1,12</sup>, Tanaya Roychowdhury<sup>1</sup>, Palak Panchal<sup>1</sup>, Liza Shrestha<sup>1</sup>, Yanlong Kang<sup>1</sup>, Sahil Sharma<sup>1</sup>, Yogita Patel<sup>2</sup>, Justina Almadovar<sup>1</sup>, Adriana Corben<sup>3,13</sup>, Mary Alpaugh<sup>1,14</sup>, Shanu Modi<sup>4</sup>, Monica L. Guzman<sup>5</sup>, Teng Fei<sup>6</sup>, Tony Taldone<sup>1</sup>, Stephen D. Ginsberg<sup>7,8</sup>, Hediye Erdjument-Bromage<sup>9</sup>, Thomas A. Neubert<sup>9</sup>, Katia Manova-Todorova<sup>10</sup>, Jason C. Young<sup>2</sup>,<strong> </strong>Meng-Fu Bryan Tsou<sup>10</sup><strong>, </strong>Tai Wang<sup>1,*</sup>, Gabriela Chiosis<sup>1,4,*</sup></p> <p><strong>Abstract </strong></p> <p>Systems-level assessments of protein-protein interaction (PPI) network dysfunctions are currently out-of-reach because approaches enabling proteome-wide identification, analysis, and modulation of context-specific PPI changes in native (unengineered) cells and tissues are lacking. Herein, we take advantage of first-in-class chemical binders of maladaptive scaffolding structures termed epichaperomes and develop an epichaperome-based ‘omics platform, epichaperomics, to identify PPI alterations in disease. We provide multiple lines of evidence, at both biochemical and functional levels, demonstrating the importance of these probes to identify and study PPI network dysfunctions and provide mechanistically and therapeutically relevant proteome-wide insights. As proof-of-principle, we derive systems-level insight into PPI dysfunctions of cancer cells which enabled the discovery of a context-dependent mechanism by which cancer cells enhance the fitness of mitotic protein networks. Importantly, our systems levels analyses support the use of epichaperome chemical binders as therapeutic strategies aimed at normalizing PPI networks. </p>
Data from: Physiological effects of interacting native and invasive bivalves under thermal stress
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.