Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
80
datasets available to search
ShareScore release 0.9.0
Dataset results
80 results for “synthetic RNA”
Synthetic bulk RNA-Seq transcriptomic profiles representing 10 Cancer hallmarks
Open the record for dataset details and reuse information.
Sequencing summaries & Nanopolish eventalign outputs for downstream analysis of yeast RNA and synthetic oligonucleotides
<p>This dataset contains:</p> <ol> <li>A set of text files from running the tool Nanopolish eventalign on several nanopore direct RNA sequencing data sets produced by Jay Hesselberth's lab at the University of Colorado (BioProject accession number <a href="https://www.ncbi.nlm.nih.gov/bioproject/?term=PRJNA910992">PRJNA910992</a>), as well as external sequencing data sets from <a href="https://pubmed.ncbi.nlm.nih.gov/34893601/">PMID: 34893601</a> (synthetic oligonucleotides from Leger et al) and <a href="https://pubmed.ncbi.nlm.nih.gov/35252946/">PMID: 35252946</a> (yeast rRNA data from Stephenson et al).</li> <li>"Sequencing summary" files produced by MinKNOW, from nanopore sequencing of yeast mRNA and synthetic RNA oligos in the Hesselberth lab. We analyze these files in an associated manuscript to determine the "end status" of each read during the sequencing run.</li> </ol> <p>These files can be used as inputs to the R markdown documents at <a href="https://github.com/hesselberthlab/RNARePore">https://github.com/hesselberthlab/RNARePore</a> to reproduce the figures in the associated manuscript.</p>
Generation of synthetic whole-slide image tiles of tumours from RNA-sequencing data via cascaded diffusion models
Open the record for dataset details and reuse information.
A synthetic RNA editing factor edits its target site in chloroplasts and bacteria
<p><span><span><span><span><span><span><span><span><span><span><span>Members of the pentatricopeptide repeat (PPR) protein family act as specificity factors in C-to-U RNA editing. The expansion of the PPR superfamily in plants provides the sequence variation required for design of consensus-based RNA-binding proteins. We used this approach to design a synthetic RNA editing factor to target one of the sites in the <i>Arabidopsis</i> chloroplast transcriptome recognised by the natural editing factor CHLOROPLAST BIOGENESIS 19 (CLB19). We show that our synthetic editing factor specifically recognises the target sequence in in vitro binding assays. The designed factor is equally specific for the target <i>rpoA</i> site when expressed in chloroplasts and in the bacterium <i>E. coli</i>. This study serves as a successful pilot into the design and application of programmable RNA editing factors based on plant PPR proteins. </span></span></span></span></span></span></span></span></span></span></span></p>
A synthetic RNA editing factor edits its target site in chloroplasts and bacteria
Open the record for dataset details and reuse information.
Data - Synthetic mammalian RNA-based gene circuits for high fold change expression
Open the record for dataset details and reuse information.
Increased translation driven by a non-canonical EZH2 cistrome creates a synthetic vulnerability in enzalutamide-resistant prostate cancer (RNA-Seq LNCaP)
GEO Series GSE266950. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
BET inhibition induces synthetic lethality in BRCA2-deficient pancreatic cancer via autophagy-dependent cell death [RNA-Seq]
GEO Series GSE207295. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
Systematic functional characterization of BAF mutations yields novel intra-complex synthetic lethalities [RNA-Seq]
GEO Series GSE108388. Homo sapiens. 87 samples. Type: Expression profiling by high throughput sequencing.
mRNA expression in iPS cells generated by a synthetic self-replicative RNA
GEO Series GSE38265. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
RNA-seq of Arabidopsis thaliana seedlings growing in the presence of a bacterial synthetic community under full and low phosphate conditions
GEO Series GSE102248. Arabidopsis thaliana. 429 samples. Type: Expression profiling by high throughput sequencing.
CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300 mutated lymphomas [RNA-seq_MEF]
GEO Series GSE152666. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Alteration of the N6-methyladenosine Epitranscriptome Profile in Synthetic Phthalate-treated Human Induced Pluripotent Stem Cell-Derived Endothelial Cells [RNA-seq]
GEO Series GSE212641. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Oxidized 5-methylcytosine modulates synthetic lethality to poly-ADP-ribose polymerase inhibitors in acute myeloid leukemia [murine AE9a RNA-seq]
GEO Series GSE217586. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Synthetic epigenetic reprogramming of mesenchymal to epithelial states using the CRISPR/dCas9 platform in triple negative breast cancer [RNA-seq]
GEO Series GSE210274. Homo sapiens. 27 samples. Type: Expression profiling by high throughput sequencing.
RNA-seq of GM15850 and GM15851 cells treated with synthetic transcription elongation factors.
GEO Series GSE99400. Homo sapiens. 40 samples. Type: Expression profiling by high throughput sequencing.
Synthetic Introns Identify GPATCH8 as Required for Mis-splicing by SF3B1 Mutations [RNA-Seq 2]
GEO Series GSE262021. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Combinatorial Gene Essentiality and Pharmacological Profiling uncovers enhancer-mediated synthetic lethal interactions with Mediator Kinase [RNA-Seq]
GEO Series GSE163819. Homo sapiens. 26 samples. Type: Expression profiling by high throughput sequencing.
RNA-seq of Arabidopsis thaliana seedlings growing in the presence of a bacterial synthetic community under full and low phosphate conditions [PBI_preTreat]
GEO Series GSE87337. Arabidopsis thaliana. 144 samples. Type: Expression profiling by high throughput sequencing.
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo [RIP-Seq]
GEO Series GSE62305. Homo sapiens. 7 samples. Type: Non-coding RNA profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.