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44 results for “systems medicine”
OMOP2OBO: Semantic Integration of Standardized Clinical Terminologies to Power Translational Digital Medicine Across Health Systems (Recorded Introduction)
<p>This entry contains the recorded introduction that was presented at the 2020 Observational Health Data Science Initiative Symposium (<a href="https://www.ohdsi.org/events/2020-ohdsi-symposium/">https://www.ohdsi.org/events/2020-ohdsi-symposium/</a>).</p>
Annotated compounds in extracts from alpine aromatic and medicinal plants grown in an aeroponics system
<p>The compounds were annotated by comparing the experimental HRMS/MS spectra of the samples with an <em>in silico</em> MS/MS spectral database of natural products.</p>
A Study to Learn About the Study Medicines (Nirmatrelvir Plus Ritonavir) in People Aged 12 Years or Older With COVID-19 and a Compromised Immune System
ClinicalTrials.gov study NCT05438602. IPD Sharing: YES. Countries: 9. Publications: 3.
A Trial to Explore Acceptance and Performance of Using a Digital Medicine System With Healthcare Professionals and Adults With Schizophrenia, Schizoaffective Disorder, or First Episode Psychosis on an
ClinicalTrials.gov study NCT03568500. IPD Sharing: YES. Countries: 1. Publications: 2.
Exploratory Trial to Assess the Functionality of an Integrated Call Center for the Digital Medicine System
ClinicalTrials.gov study NCT02722967. IPD Sharing: NO. Countries: 1. Publications: 1.
Experimental Data for "What Makes a Top-Performing Precision Medicine Search Engine? Tracing Main System Features in a Systematic Way" at SIGIR2020
<p>This deposit contains data used for the experiments reported in the paper "<a href="https://doi.org/10.1145/3397271.3401048">What Makes a Top-Performing Precision Medicine Search Engine? Tracing Main System Features in a Systematic Way</a>", most notably the ElasticSearch 5.4 indices used for the reported experiments.</p> <p>To load the indices into an ElasticSearch cluster of your own, use the restore function described in the <a href="https://www.elastic.co/guide/en/elasticsearch/reference/5.4/modules-snapshots.html">ElasticSearch documentation</a>.</p> <p>The names of the index snapshots contained here are</p> <ul> <li>ct1718 for the indexed ClinicalTrials data used in the TREC-PM challenges in <a href="http://www.trec-cds.org/2017.html">2017</a> and <a href="http://www.trec-cds.org/2018.html">2018</a>.</li> <li>ct19 for the indexed ClinicalTrials data used in the TREC-PM challenge in <a href="http://www.trec-cds.org/2019.html">2019</a>.</li> <li>ba1718 for the indexed PubMed data used in the TREC-PM challenges in <a href="http://www.trec-cds.org/2017.html">2017</a> and <a href="http://www.trec-cds.org/2018.html">2018</a>.</li> <li>ba19 for the indexed PubMed data used in the TREC-PM challenge in <a href="http://www.trec-cds.org/2019.html">2019</a>.</li> </ul> <p>The other file contains the original output that <a href="https://www.automl.org/automated-algorithm-design/algorithm-configuration/smac/">SMAC</a> wrote to disc during the parameter optimization process. There are directories for the biomedical abstracts (BA) and clinical trials (ct) and for each respective 10 fold cross validation split. Those file contain the exact parameter configurations and their evalation score (the infNDCG metric was used) in live-runXX.json files.</p> <p>The code to these files is located in <a href="https://zenodo.org/record/3856403">this Zenodo deposit</a>.</p>
Data from: Toxins or medicines? Phytoplankton diets mediate host and parasite fitness in a freshwater system
Diets must satisfy the everyday metabolic requirements of organisms and can also serve as medicines to combat disease. Currently, the medicinal role of diets is much better understood in terrestrial than in aquatic ecosystems. This is surprising because phytoplankton species synthesize secondary metabolites with known antimicrobial properties. Here, we investigated the medicinal properties of phytoplankton (including toxin-producing cyanobacteria) against parasites of the dominant freshwater herbivore, Daphnia. We fed Daphnia dentifera on green algae and toxic cyanobacteria diets known to vary in their nutritional quality and toxin production, and an additional diet of Microcystis with added pure microcystin-LR. We then exposed Daphnia to fungal and bacterial parasites. Anabaena, Microcystis and Chlorella diets prevented infection of Daphnia by the fungal parasite Metschnikowia, while Nodularia toxins increased offspring production by infected hosts. In contrast to their medicinal effects against Metschnikowia, toxic phytoplankton generally decreased the fitness of Daphnia infected with the bacterial parasite, Pasteuria. We also measured the amount of toxin produced by phytoplankton over time. Concentrations of anatoxin-a produced by Anabaena increased in the presence of Metschnikowia, suggesting parasite-induced toxin production. Our research illustrates that phytoplankton can serve as toxins or medicines for their consumers, depending upon the identity of their parasites.
Emergency Medicine: Life-Saving Strategies and Techniques - Prehospital Emergency Care, Triage Systems, Advanced Card Apologies for the premature response.
<p><span>Emergency medicine is a critical field that plays a pivotal role in saving lives and providing essential care during life-threatening situations. This paper aims to explore the key components of emergency medicine, with a focus on prehospital emergency care, triage systems, and advanced cardiac apologies. Through an in-depth analysis of current practices, strategies, and techniques, this paper provides valuable insights into the life-saving measures employed in emergency medicine.</span></p>
Traditional Chinese Medicine (TCM) for Temporomandibular Dysfunction (TMD): A Whole Systems Multi-site Trial
ClinicalTrials.gov study NCT00856167. IPD Sharing: Not stated. Countries: 0. Publications: 2.
Study of Osteopathic Manipulative Medicine on the Autonomic Nervous System
ClinicalTrials.gov study NCT02193373. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Using the EHR to Advance Genomic Medicine Across a Diverse Health System
ClinicalTrials.gov study NCT06377033. IPD Sharing: NO. Countries: 1. Publications: 1.
Angina After PCI: a Systems Medicine Study
ClinicalTrials.gov study NCT06854302. IPD Sharing: YES. Countries: 1. Publications: 1.
Clinical & Systems Medicine Investigations of Smoking-related Chronic Obstructive Pulmonary Disease
ClinicalTrials.gov study NCT02627872. IPD Sharing: YES. Countries: 1. Publications: 17.
Individualized Systems Medicine Functional Profiling for Recurrent Glioblastoma
ClinicalTrials.gov study NCT05043701. IPD Sharing: NO. Countries: 1. Publications: 2.
SMART - Systems Medicine of Heart Failure
ClinicalTrials.gov study NCT03172338. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Metagenomics and Integrative Systems Medicine of Cardiometabolic Diseases
ClinicalTrials.gov study NCT02059538. IPD Sharing: Not stated. Countries: 3. Publications: 1.
Open Video System in Medicine (oVID)
ClinicalTrials.gov study NCT06054048. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Research Study to Evaluate the Effects of a New Oral Medicine Called Cenerimod in Adults With Systemic Lupus Erythematosus
ClinicalTrials.gov study NCT05648500. IPD Sharing: NO. Countries: 17. Publications: 1.
Systems Medicine to Study Necrotizing Soft Tissue Infections (NSTIs).
ClinicalTrials.gov study NCT01790698. IPD Sharing: Not stated. Countries: 3. Publications: 6.
Data from: Toxins or medicines? Phytoplankton diets mediate host and parasite fitness in a freshwater system
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.