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ShareScore release 0.9.0
Dataset results
46 results for “targeted support”
Phenome-wide association studies across large population cohorts support drug target validation
<p>Summary-level data generated by Genomics plc as presented in:<br> Diogo, D. et al. Phenome-wide association studies across large population cohorts support drug target validation. Nat. Commun. 9, 4285 (2018). https://doi.org/10.1038/s41467-018-06540-3</p> <p>If you have any questions or comments regarding these files, please contact Genomics plc at <a href="mailto:research@genomicsplc.com">research@genomicsplc.com</a></p> <p>NOTES<br> -----------------------------<br> These analyses were carried out using the interim UK Biobank imputation data release. Analyses were restricted to a subset of "white-British" unrelated samples with a maximum sample size of 112,337 individuals. </p> <p>Case control phenotypes were defined based on categorical datafields as listed in the accompanying file. <br> Quantitative phenotypes were either rank-normalised before analysis, or beta/se values were standardised after analysis using the variance of the phenotype. The normalisation value is indicated in the accompanying file.<br> <br> All analyses included Age at assessment, sex, genotyping chip, and 10 principal components as covariates. </p> <p>We used plink1.9 linear/logistic regression as appropriate. For chromosome X variants males were treated as having 0 or 2 alternative alleles. </p> <p>The results are not adjusted for genomic control.</p> <p>DATA FILE CONTENT DESCRIPTION<br> -----------------------------<br> CHR - Chromosome<br> SNP - Variant rsID<br> ALT - Alternative allele (effect allele)<br> REF - Reference Allele (non-effect allele)<br> BP - Position in base pairs (b37, 1-based)<br> NMISS - Number of samples with non-missing genotypes<br> BETA - Effect size (log odds ratio or standardised effect size)<br> SE - Standard error<br> P - P-value<br> F_MISS - genotype missing rate<br> P_hwe - Hardy-weinberg p-value<br> MAF - ALT allele frequency</p>
Supporting data for "Quality control for the target decoy approach for peptide identification"
<p>Supporting data for the manuscript "Quality control for the target decoy approach for peptide identification". Input files are raw mass spectrometry runs, to be downloaded from the PRIDE Archive (https://www.ebi.ac.uk/pride/), which can be processed with the parameter files, Nextflow workflow, and Python scripts in "workflow-scripts-parameters.zip". The resulting output files that were used for the manuscript are provided in search-results.zip.</p>
Clinical Trial of a Supporter-Targeted Intervention to Improve Outcomes in Recent Sexual Assault Survivors
ClinicalTrials.gov study NCT05345405. IPD Sharing: YES. Countries: 1. Publications: 1.
Data supporting "Lessons learned from multi-objective automatic optimizations of classical three-site rigid water models using microscopic and macroscopic target experimental observables"
<p>This repository contains the set of data and the code to reproduce the results shown in "Lessons learned from multi-objective automatic optimizations of classical three-site rigid water models using microscopic and macroscopic target experimental observables" published on Journal of Chemical Engineering and Data (DOI: 10.1021/acs.jced.3c00538).</p>
Research data supporting ""Lessons learned from multi-objective automatic optimizations of classical three-site rigid water models using microscopic and macroscopic target experimental observables""
<p>This repository contains the set of data and the code to reproduce the results shown in "Lessons learned from multi-objective automatic optimizations of classical three-site rigid water models using microscopic and macroscopic target experimental observables" published on Journal of Chemical Engineering and Data (DOI: 10.1021/acs.jced.3c00538).</p>
Data in Support of: Coal Exit Policy Must Confront Loopholes and Laggards for Political Momentum to Matter for Paris Targets
<p>Input and output data of COALogit and REMIND, which generated the dynamic feasibility space of national accession to the Powering Past Coal Alliance (PPCA) and the long-term energy system and emissions impacts of PPCA-induced coal phase-out scenarios, respectively. </p>
Data in support of Using target sequence capture to improve the phylogenetic resolution of a rapid radiation in New Zealand Veronica
<p>Includes alignments and trees for the analysis found in Thomas et al. 2021, Using target sequence capture to improve the phylogenetic resolution of a rapid radiation in New Zealand Veronica; American Journal of Botany, Special Issue: Exploring Angiosperms353: a Universal Toolkit for Flowering Plant Phylogenomics. Alignments comprise subsets of Angiosperms353 genes given each filtering scheme (full, intersection, sortadate_BP, sortadate_TL) and gene type/subset (exons, introns, supercontigs), and for markers downloaded from GenBank, as explained in the Methods section of Thomas et al. 2021. Trees were included for each of these alignments from IQtree and Astral; SVDquartets tree was only estimated for the full set of supercontigs. Gene trees were generated with IQtree. Tree files are named differently than the final manuscript; refer to the number of genes specified in Fig 1 of Thomas et al, 2021 and specified in each filename to identify filtering scheme. Raw sequence reads are available on the Sequence Read Archive at <a href="http://www.ncbi.nlm.nih.gov/bioproject/715342">http://www.ncbi.nlm.nih.gov/bioproject/715342</a>.</p>
Support data for conference paper "Assessment of Communication Resource Allocation by the Transmission Control Protocol for the Target Virtual Connection under Competitive Conditions"
<p>Support data for article</p> <p>V. Kovtun, O. Kovtun, K. Grochla, and K. Połys, “Assessment of Communication Resource Allocation by the Transmission Control Protocol for the Target Virtual Connection under Competitive Conditions,” Electronics, vol. 13, no. 7. MDPI AG, p. 1180, Mar. 22, 2024. doi: 10.3390/electronics13071180.</p> <div> <p>This research is part of the project No. 2022/45/P/ST7/03450 co-funded by the National Science Centre and the European Union Framework Programme for Research and Innovation Horizon 2020 under the Marie Skłodowska-Curie grant agreement No. 945339.</p> </div>
Supporting Information: Exploring Novel Antimalarial Compounds Targeting Plasmodium falciparum Enoyl-ACP Reductase: Computational and Experimental Insights
<ul> <li>Library 1 with molecules already tested in vitro against PfENR in .sdf format. for the first molecular docking.</li> <li>.omv file of data used for ROC curve analysis.</li> <li>Library 2 with molecules structurally similar to the leader molecules LD1 and LD2 in .sdf format.</li> <li>CHJ and TCL standards used in molecular docking and DM.</li> <li>Chain A of the PDB coded structure 4IGE with NADH used in the molecular docking experiment.</li> <li>Input files for DM in PDB format:</li> </ul> <p>- PfENR_NAD_CHJ_DM</p> <p>- PfENR_NAD_LG1_DM</p> <p>- PfENR_NAD_LG2_DM</p> <p>- PfENR_NAD_TCL_DM</p> <ul> <li>The md file contains all the necessary data, including the scripts, for reproducing Molecular Dynamics.</li> </ul>
Activating Collaborative CIS Support Via Targeted Provider Mailing
ClinicalTrials.gov study NCT00873288. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Effect of a Targeted Notification and Clinical Support Pathway on Individuals With Left Ventricular Hypertrophy
ClinicalTrials.gov study NCT05713916. IPD Sharing: YES. Countries: 1. Publications: 8.
Supporting data and libraries used for statistical analysis for the article: "Targeted metabolomic profiling reveals differences in plasma metabolome of ovalbumin sensitised guinea pigs"
<p>Supporting data and libraries used for statistical analysis for the article: "Targeted metabolomic profiling reveals differences in plasma metabolome of ovalbumin sensitised guinea pigs"</p>
Datasets and code utilized in the development of the following manuscript: Evaluating the accuracy of eight satellite and reanalysis daily precipitation estimates over Angola: The advantages of targeted regional evaluations to support effective water management strategies
<p>Datasets and code utilized in the development of the following manuscript: Evaluating the accuracy of eight satellite and reanalysis daily precipitation estimates over Angola: The advantages of targeted regional evaluations to support effective water management strategies.</p>
Supported data for manuscript "Different technology packages to deliver the 1.5°C target for global aluminum smelters"
<p>This is the database of the manuscript "Different technology packages to deliver the 1.5°C target for global aluminum smelters" submitted to Nature Climate Change.</p>
Small extrachromosomal circular DNA harboring targeted tumor suppressor gene mutations supports intratumor heterogeneity in mouse liver cancer induced by multiplexed CRISPR/Cas9
<p>These files include raw image data from our study titled "Small extrachromosomal circular DNA containing targeted tumor suppressor mutations supports intratumoral heterogeneity in multiplex CRISPR/Cas9-induced mouse liver cancer".</p>
Organisational Models Supported by Technology for the Management of Diabetic Disease and Its Complications in a Diabetic Clinic Setting. A Randomised Controlled Trial Targeting Type 2 Diabetes Individ
ClinicalTrials.gov study NCT05629221. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Inspiratory Effort-Targeted Pressure Support Ventilation (IT-PSV) Trial
ClinicalTrials.gov study NCT06526598. IPD Sharing: NO. Countries: 1. Publications: 1.
Clinical Trial of Telenursing for Monitoring Supportive Care Needs in Patients With Lung Cancer and Melanoma Candidates for the First Prescription of Targeted Therapies
ClinicalTrials.gov study NCT06254196. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Diabetes Prevention Study Targeting High Risk Individuals With Education and Ongoing Support
ClinicalTrials.gov study NCT00677937. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Social Support Intervention Targeting Patients Treated for Cardiac Disease Who Experience Loneliness
ClinicalTrials.gov study NCT05503810. IPD Sharing: Not stated. Countries: 1. Publications: 2.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.