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ShareScore release 0.9.0
Dataset results
51 results for “telencephalon”
A telencephalon cell type atlas for goldfish reveals diversity in the evolution of spatial structure and cell types
<p class="MsoNormal"><span>Teleost fish form the largest group of vertebrates, making them critically important for the study on the</span> <span>mechanisms of brain evolution. In fact, teleosts show a tremendous variety of adaptive behaviors similar</span> <span>to birds and mammals, however, the neural basis mediating these behaviors remains elusive. We</span> <span>performed a systematic comparative survey of the goldfish telencephalon: the seat of plastic behavior,</span> <span>learning, and memory in vertebrates. We delineated and mapped goldfish telencephalon cell types using</span> <span>single-cell RNA-seq and spatial transcriptomics, resulting in de novo molecular neuroanatomy</span> <span>parcellation. Glial cells were highly conserved across 450 million years of evolution separating mouse</span> <span>and goldfish, while neurons showed diversity and modularity in gene expression. Specifically,</span> <span>somatostatin (SST) interneurons, famously interspersed in the mammalian isocortex for local inhibitory</span> <span>input, were curiously aggregated in a single goldfish telencephalon nucleus, but molecularly conserved.</span> <span>Cerebral nuclei including the striatum, a hub for motivated behavior in amniotes, had molecularly conserved goldfish homologs. We further suggest different elements of a hippocampal formation across</span> <span>the goldfish pallium. Finally, aiding study of the teleostan everted telencephalon, we describe substantial</span> <span>molecular similarities between the goldfish and zebrafish neuronal taxonomies. Together, our atlas</span> <span>provides new insights into organization and evolution of vertebrate forebrains and may serve as a resource</span> <span>for the functional study underlying cognition in teleost fish.</span></p>
A telencephalon cell type atlas for goldfish reveals diversity in the evolution of spatial structure and cell types
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scRNAseq of Danio rerio telencephalon
<p>scRNA-sequencing dataset of Danio rerio telencephalon is provided for easier access as .rds objects:</p><ul><li>telencephalon_cells.rds contains all cells and their respective supercluster-ID</li><li>neurons.subset.rds contains all neuronal cell types and their subcluster ID</li></ul>
Androgen and prolactin manipulation do not induce changes in gene expression in the telencephalon in parental male bluegill (Lepomis macrochirus) during parental care
<p>Transcriptome of the prosencephalon of 11-KT, prolactin and placebo implanted fish.</p>
Social fish have larger brains and greater relative telencephalon sizes: support for the social brain hypothesis from wild, intraspecific comparisons
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DNA methylation regulates transcription factor specific neurodevelopmental but not sexually dimorphic gene expression dynamics in zebra finch telencephalon
<p>Supplementary Information for the manuscript: "DNA methylation regulates transcription factor specific neurodevelopmental but not sexually dimorphic gene expression dynamics in zebra finch telencephalon"</p>
A Chromatin Accessibility Atlas of the Developing Human Telencephalon
GEO Series GSE149268. Homo sapiens. 40 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
TCF4 regulatory gene networks in developing dorsal telencephalon
GEO Series GSE79663. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
A single-cell transcriptome atlas of the zebrafish telencephalon
GEO Series GSE212314. Danio rerio. 16 samples. Type: Expression profiling by high throughput sequencing.
DNA methylation regulates transcription factor specific neurodevelopmental but not sexually dimorphic gene expression dynamics in zebra finch telencephalon [RNA-Seq]
GEO Series GSE147972. Taeniopygia guttata. 24 samples. Type: Expression profiling by high throughput sequencing.
Deep learning of enhancer codes highlights similarities between mammalian and avian telencephalon cell types [stereoseq]
GEO Series GSE262322. Gallus gallus. 1 samples. Type: Other.
AURATUS goldfish environmental genomics projects: SKF 38393 in the telencephalon
GEO Series GSE14608. Carassius auratus; Cyprinus carpio. 4 samples. Type: Expression profiling by array.
RNA sequencing of control and CTCF-null embryonic day 14 telencephalon
GEO Series GSE105070. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
AURATUS goldfish environmental genomics projects: quinpirole in the telencephalon
GEO Series GSE14609. Carassius auratus; Cyprinus carpio. 4 samples. Type: Expression profiling by array.
AURATUS goldfish environmental genomics projects: sulpiride in the telencephalon
GEO Series GSE15705. Cyprinus carpio; Carassius auratus. 4 samples. Type: Expression profiling by array.
A High-Resolution Enhancer Atlas of the Developing Telencephalon
GEO Series GSE42881. Mus musculus; Homo sapiens. 3 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
AURATUS goldfish environmental genomics projects: SCH 23390 in the telencephalon
GEO Series GSE15707. Cyprinus carpio; Carassius auratus. 4 samples. Type: Expression profiling by array.
Deep learning of enhancer codes highlights similarities between mammalian and avian telencephalon cell types [mpra]
GEO Series GSE262320. Mus musculus. 6 samples. Type: Other.
CTCF occupancy in the mouse telencephalon and medial ganglionic eminence
GEO Series GSE105071. Mus musculus. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Deep learning of enhancer codes highlights similarities between mammalian and avian telencephalon cell types [multiome]
GEO Series GSE262321. Gallus gallus. 4 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.