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22
datasets available to search
ShareScore release 0.7.1
Dataset results
22 results for “termination codon”
TAILVAR (Terminal codon Analysis and Improved prediction of Lengthened VARiants)
<p>This dataset includes relevant files for developing the TAILVAR score designed to assess the functional impact of <strong>stop-loss variants</strong> occurring at stop codons (TAA, TGA, TAG). <strong>TAILVAR</strong> is built using a Random Forest model that predicts the pathogenicity of <strong>stop-loss variants</strong>. By integrating a combination of in-silico prediction scores, transcript features, and protein context information, <strong>TAILVAR</strong> provides a score ranging from 0 to 1, indicating the probability of a variant being pathogenic.</p> <p>For more information, please visit <a href="https://github.com/dr-yoon/TAILVAR">https://github.com/dr-yoon/TAILVAR</a></p>
Data for Bernabeu-Herrero et al, Mutations causing premature termination codons discriminate and generate cellular and clinical variability in HHT
<p>This dataset is for the 2024 manuscript<strong>: </strong></p> <p><strong>Bernabéu-Herrero ME, Patel D, Bielowka A, Zhu J, Jain K, Mackay IS, Chaves Guerrero P, Emanuelli G, Jovine L, Noseda M, Marciniak SJ, Aldred MA, Shovlin CL. </strong></p> <p><strong>Mutations causing premature termination codons discriminate and generate cellular and clinical variability in HHT. </strong></p> <p><strong>Blood. 2024 May 30;143(22):2314-2331. </strong></p> <p><strong>doi: 10.1182/blood.2023021777. PMID: 38457357; PMCID: PMC11181359.</strong></p> <p>It was originally uploaded in 2021 ahead of an earlier manuscript submission<br>- see https://www.biorxiv.org/content/10.1101/2021.12.05.471269v1</p>
Novel Therapeutic Approaches for Treatment of CF Patients With W1282X Premature Termination Codon Mutations
ClinicalTrials.gov study NCT03624101. IPD Sharing: NO. Countries: 1. Publications: 0.
TLN468 changes the pattern of tRNA used to read through premature termination codons in CFTR
GEO Series GSE246353. Homo sapiens. 6 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Efficient suppression of premature termination codons with alanine by engineered chimeric pyrrolysine tRNAs [Ribo-Seq]
GEO Series GSE277130. Homo sapiens. 4 samples. Type: Other.
Stop Codon Context Influences Genome-Wide Stimulation of Termination Codon Readthrough by Aminoglycosides [Dataset 1]
GEO Series GSE138638. Homo sapiens. 26 samples. Type: Expression profiling by high throughput sequencing.
Stop Codon Context Influences Genome-Wide Stimulation of Termination Codon Readthrough by Aminoglycosides [Dataset 3]
GEO Series GSE138640. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomic analysis of premature termination codon mutation in the zebrafish gene psen2
GEO Series GSE148468. Danio rerio. 12 samples. Type: Expression profiling by high throughput sequencing.
Stop Codon Context Influences Genome-Wide Stimulation of Termination Codon Readthrough by Aminoglycosides
GEO Series GSE138643. Homo sapiens. 41 samples. Type: Expression profiling by high throughput sequencing.
Identification of transcripts harboring premature termination codons by NMD inhibition in a panel of CCRCC cell lines
GEO Series GSE20491. Homo sapiens. 99 samples. Type: Expression profiling by array.
Stop Codon Context Influences Genome-Wide Stimulation of Termination Codon Readthrough by Aminoglycosides [Dataset 2]
GEO Series GSE138639. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Small molecule Y-320 stimulates ribosome biogenesis, protein synthesis and aminoglycoside-induced premature termination codon readthrough
GEO Series GSE152142. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Stop Codon Context Influences Genome-Wide Stimulation of Termination Codon Readthrough by Aminoglycosides [Dataset 4]
GEO Series GSE138641. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Stop Codon Context Influences Genome-Wide Stimulation of Termination Codon Readthrough by Aminoglycosides [Dataset 5]
GEO Series GSE138642. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Efficient suppression of premature termination codons with alanine by engineered chimeric pyrrolysine tRNAs
GEO Series GSE277128. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Near-cognate tRNAs increase the efficiency and precision of pseudouridine-mediated readthrough of premature termination codons [PRAISE]
GEO Series GSE237632. Homo sapiens. 5 samples. Type: Expression profiling by high throughput sequencing.
Near-cognate tRNAs increase the efficiency and precision of pseudouridine-mediated readthrough of premature termination codons [Target-seq]
GEO Series GSE237629. Homo sapiens; Mus musculus. 27 samples. Type: Other; Expression profiling by high throughput sequencing.
Near-cognate tRNAs increase the efficiency and precision of pseudouridine-mediated readthrough of premature termination codons
GEO Series GSE237633. Mus musculus; Homo sapiens. 70 samples. Type: Expression profiling by high throughput sequencing; Other; Non-coding RNA profiling by high throughput sequencing.
Near-cognate tRNAs increase the efficiency and precision of pseudouridine-mediated readthrough of premature termination codons [tRNA-seq]
GEO Series GSE237630. Homo sapiens. 26 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Near-cognate tRNAs increase the efficiency and precision of pseudouridine-mediated readthrough of premature termination codons [RNA-seq]
GEO Series GSE237631. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.