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549 results for “test and treatment”
Data from: Testing the heat treatment dose for Agrilus planipennis prepupae using the Humble water bath
<p>The lethal heat treatment dose (time and temperature) for the pre-pupal life stage of <em>Agrilus planipennis</em> Fairmaire (Coleoptera: Buprestidae), emerald ash borer, was determined through an in vitro application using a carefully calibrated heat treatment apparatus. The lethal and sublethal effects of heat on A. planipennis prepupae were assessed through a ramped heat delivery application, simulating industrial kilns and conventional heat chamber operations, for treatments combining target temperatures of 54 °C, 55 °C, and 56 °C, and exposure durations of 0 min (i.e., kiln temperature ramp only), 15 min, or 30 min. Prepupal emerald ash borer larvae did not survive exposure to 56 °C for 15 min or longer, or to 55 °C for 30 min. Sublethal effects were observed for all other treatments. Sublethal effects included delayed development and failure to complete the pupal and adult life stages. The datasets and associated R statistical computing langauge code are deposited here.</p>
Caudal fin area: body length ratio (A:L 2; mean..) FIGURE 5 CF s S E measured from photographs of Salmo trutta parr at 20 and 32 weeks after exercise treatment initiation. A:L 2 values between the two CF s groups were significantly different (Welch's two sample t- test p <0.05) in Body shape and robustness response to water flow during development of brown trout Salmo trutta parr
Caudal fin area: body length ratio (A:L 2; mean..) FIGURE 5 CF s S E measured from photographs of Salmo trutta parr at 20 and 32 weeks after exercise treatment initiation. A:L 2 values between the two CF s groups were significantly different (Welch's two sample t- test p <0.05)
Tensile tests results on artificially aged aluminum-magnesium-silicon alloy blanks subjected to different localized heat treatment strategies
<p>Tensile tests results on artificially aged aluminum-magnesium-silicon alloy blanks subjected to different localized heat treatment strategies </p>
Influence of endosymbionts on the reproductive fitness of the tick Ornithodoros moubata tested through elimination of the microbiota using antibiotic treatments
<p class="MsoNoSpacing">Over the past ten years, many studies demonstrated the crucial role of the tick microbiome in tick biology. The soft tick <em>Ornithodoros moubata</em> is a hematophagous ectoparasite of Suidae particularly known to transmit the African swine fever virus. Its bacterial microbiota is characterized by a high prevalence of <em>Francisella</em>-like and <em>Rickettsia</em> endosymbionts. The present study aims to better understand the potential influence of the microbiota on the reproductive fitness of <em>O. moubata</em>. A total of 132 adult female ticks were treated using gentamycin or rifampicin added to the blood meal. Half of the ticks also received a supplementation with B vitamins to address the nutritional role of endosymbionts. Over two periods of 50 days, several traits related to reproductive fitness were monitored to investigate the importance of <em>Francisella</em> and <em>Rickettsia</em> for those traits. It appeared that most of the considered reproductive parameters were not affected. However, antibiotic treatments induced an increase in the tick survival indicating a potential fitness cost of harboring endosymbionts for ticks during the reproduction period. Similarly, 366 first-stage nymphs of <em>Ornithodoros moubata</em> were exposed to the same treatments for molecular quantification of both endosymbionts. Results from qPCR suggested that treatments produced a bacteriostatic effect on endosymbionts without fully eliminating <em>Francisella</em> or <em>Rickettsia</em>.</p>
Developing and testing protocols for fouling treatments on oysters
<p>Aim: Develop protocols for effective fouling treatment on oysters (Ostrea edulis and Magallana gigas) in the lab.</p> <p>Fouling treatments were evaluated using lab trials (in tanks) for evaluation of effects of heat treatment of fouling organisms on oysters. A range of different temperatures and exposure times was evaluated. The data consists of parameters associated with the treatments (temperature) and survival of oysters, survival of fouling organisms. Data originates from the Swedish west coast.</p>
MEND 2: Making Treatment Decisions Using Genomic Testing
ClinicalTrials.gov study NCT03183050. IPD Sharing: YES. Countries: 1. Publications: 2.
Swab Testing to Optimize Pneumonia Treatment with Empiric Vancomycin
ClinicalTrials.gov study NCT06272994. IPD Sharing: YES. Countries: 1. Publications: 24.
CHALO! 2.0: A Mobile Technology Based Intervention to Accelerate HIV Testing and Linkage to Preventive Treatment.
ClinicalTrials.gov study NCT04814654. IPD Sharing: YES. Countries: 1. Publications: 1.
A Study to Test if TV-46000 is Safe for Maintenance Treatment of Schizophrenia
ClinicalTrials.gov study NCT03893825. IPD Sharing: YES. Countries: 5. Publications: 3.
Influence of endosymbionts on the reproductive fitness of the tick Ornithodoros moubata tested through elimination of the microbiota using antibiotic treatments
Open the record for dataset details and reuse information.
Data from: Testing the heat treatment dose for Agrilus planipennis prepupae using the Humble water bath
Open the record for dataset details and reuse information.
Data about upper limb kinematics to test the efficacy of Action Observation Treatment
<p>The dataset contains the upper-limb kinematics collected in 40 participants before and after a short-term immobilization of the right arm. Three reach-to-grasp movements were required, targeting an object placed a) frontally at the level of the shoulders (A_low), b) frontally above the head (A_high), or c) laterally at the level of the shoulders (L_low). These movements were intended to test different degrees of freedom of the shoulder joint.</p> <p>Half of the participants underwent a virtual-reality action observation treatment (see Rizzolatti et al, Neuroscience and Biobehabioral Reviews, 2021), while the control group underwent a non-motor VR stimulation.</p>
Deep-sequence phylogenetics to quantify patterns of HIV transmission in the context of a universal testing and treatment trial – BCPP/ Ya Tsie trial
<p><strong>Background:</strong> Mathematical models predict that community-wide access to HIV testing-and-treatment can rapidly and substantially reduce new HIV infections. Yet several large universal test-and-treat HIV prevention trials in high-prevalence epidemics demonstrated variable reduction in population-level incidence.</p> <p><strong>Methods:</strong> To elucidate patterns of HIV spread in universal test-and-treat trials we quantified the contribution of geographic-location, gender, age and randomized-HIV-intervention to HIV transmissions in the 30-community Ya Tsie trial in Botswana (estimated trial population: 175,664).</p> <p><strong>Results:</strong> Deep-sequence phylogenetic analysis revealed that most inferred HIV transmissions within the trial occurred within the same or between neighboring communities, and between similarly-aged partners. Transmissions into intervention communities from control communities were more common than the reverse post-baseline (30% [12.2 – 56.7] versus 3% [0.1 – 27.3]) than at baseline (7% [1.5 – 25.3] versus 5% [0.9 – 22.9]) compatible with a benefit from treatment-as-prevention.</p> <p><strong>Conclusion:</strong> Our findings suggest that population mobility patterns are fundamental to HIV transmission dynamics and to the impact of HIV control strategies.</p> <p><strong>Funding:</strong> This study was supported by the National Institute of General Medical Sciences (U54GM088558); the Fogarty International Center (FIC) of the U.S. National Institutes of Health (D43 TW009610); and the President's Emergency Plan for AIDS Relief through the Centers for Disease Control and Prevention (CDC) (Cooperative agreements U01 GH000447 and U2G GH001911).</p>
The impact of weekly fever-screening and treatment and monthly RDT testing and treatment on the infectious reservoir of malaria in Burkina Faso: results from a cluster-randomised trial
<p>The majority of malaria infections in endemic countries are asymptomatic and a source of onward transmission to mosquitoes. Malaria transmission and disease burden could be reduced by improving early detection and treatment of these infections with active screening approaches. In an 18-month cluster-randomized study in Sapone, Burkina Faso, households were enrolled and randomised to 1 of 3 arms: arm 1 - control; arm 2 - active weekly screening for febrile individuals and treatment if rapid diagnostic test (RDT) positive; or arm 3 – active weekly fever-screening (as arm 2) plus monthly RDT-testing regardless of symptoms. The primary outcome was parasite prevalence by qPCR in the end-of-study cross-sectional survey. Secondary outcomes included parasite and gametocyte prevalence and density in all three end-of-season cross-sectional surveys, incidence of infection, and the transmissibility of infections to mosquitoes. A total of<strong> </strong>906 individuals were enrolled during 2 phases. In Phase 1, 412 individuals were enrolled between August 9 and 17, 2018, and in Phase 2, 494 individuals were enrolled between January 10 and 31, 2019. In the end-of-study cross-sectional survey, malaria parasite prevalence by qPCR was statistically significantly lower in arm 3 (29·26% 79/270), but not in arm 2 (45·66% 121/265), when compared to arm 1 (48·72% 133/273) (RR = 0·65, 95%CI = 0·52 to 0·81, P=0·0001). Total parasite and gametocyte prevalence and density were also significantly lower in arm 3 in all surveys. The largest differences were seen at the end of the dry season, with gametocyte prevalence 78·38 % and transmission potential 98·20% lower in arm 3 vs arm 1. Active monthly RDT testing and treatment can reduce parasite carriage and the infectious reservoir of malaria to <2% when used during the dry season. This insight may inform approaches for malaria control and elimination.</p>
Results of quasi static test on CFRP/CFRP joints and CFRP/Al joint with different surface treatments within project _Spoke11_WP2_Task2.3_MOST
<p>Quasi-static single lap joint test on CFRP CFRP joints and CFRP aluminum joints. Two different epoxy adhesives have been used and different chemical surface treatments used in order to try to enhance the mechanical resistance of the single lap joint.</p>
Testing the Addition of a Radiation Sensitizing Drug, IPdR, to the Usual Chemotherapy Treatment (Capecitabine) During Radiation Therapy for Rectal Cancer
ClinicalTrials.gov study NCT04406857. IPD Sharing: YES. Countries: 1. Publications: 1.
Study to Test the Efficacy and Safety of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adults With Drug-resistant Epilepsy
ClinicalTrials.gov study NCT03373383. IPD Sharing: YES. Countries: 19. Publications: 2.
Testing the Addition of a New Anti-Cancer Drug, Triapine, to the Usual Chemotherapy Treatment (Cisplatin) During Radiation Therapy for Advanced-stage Cervical and Vaginal Cancers
ClinicalTrials.gov study NCT02466971. IPD Sharing: Not stated. Countries: 3. Publications: 2.
Testing Nivolumab as a Potential Targeted Treatment in Cancers With Mismatch Repair Deficiency (MATCH-Subprotocol Z1D)
ClinicalTrials.gov study NCT04439214. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Testing the Combination of Belinostat and SGI-110 (Guadecitabine) or ASTX727 for the Treatment of Unresectable and Metastatic Conventional Chondrosarcoma
ClinicalTrials.gov study NCT04340843. IPD Sharing: YES. Countries: 1. Publications: 1.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.