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231
datasets available to search
ShareScore release 0.9.0
Dataset results
231 results for “thrombolysis”
Fibrinogen depletion coagulopathy predicts major bleeding after thrombolysis for ischemic stroke: a multicentre study
<p>Dataset from "Fibrinogen depletion coagulopathy predicts major bleeding after thrombolysis for ischemic stroke: a multicentre study", Romoli & Vandelli et al., Stroke 2022</p>
Association of Serum Biomarkers with Early Neurological Improvement after Intravenous Thrombolysis in Ischemic Stroke
<p><strong>Background:</strong> Early neurological improvement (ENI) after intravenous thrombolysis is associated with favorable outcome, but associated serum biomarkers were not fully determined. We aimed to investigate the issue in a prospective cohort.</p> <p><strong>Methods:</strong> In INTRECIS study, five centers were designed to consecutively collect the blood sample from enrolled patients. Enrolled patients with ENI and without ENI were matched by propensity score matching with the ratio of 1:1. Preset 49 biomarkers were measured through protein microarray analysis. Enrichment of Gene Ontology and pathway, and protein-protein interaction network were analyzed in the identified biomarkers.</p> <p><strong>Results:</strong> Of 358 patients, 19 occurred ENI, who were assigned as ENI group, while 19 matched patients without ENI were assigned as Non ENI group. A total of nine biomarkers were found different, among which levels of chemokine (C-C motif) ligand (CCL)-23, chemokine (C-X-C motif) ligand (CXCL)-12, insulin-like growth factor binding protein (IGFBP)-6, interleukin (IL)-5, lymphatic vessel endothelial hyaluronan receptor (LYVE)-1, plasminogen activator inhibitor (PAI)-1, platelet-derived growth factor (PDGF)-AA, suppression of tumorigenicity (ST)-2, and tumor necrosis factor (TNF)-α were higher in ENI group, compared with those in Non ENI group.</p> <p><strong>Conclusions:</strong> Our finding found that serum levels of CCL-23, CXCL-12, IGFBP-6, IL-5, LYVE-1, PAI-1, PDGF-AA, ST-2, and TNF-α at admission were associated with post-thrombolytic ENI in ischemic stroke. The role of these biomarkers warrant further investigation.</p>
Optimum Duration of Acoustic Pulse Thrombolysis Procedure in Acute Pulmonary Embolism
ClinicalTrials.gov study NCT02396758. IPD Sharing: Not stated. Countries: 2. Publications: 2.
Standard-dose Apixaban AFtEr Very Low-dose ThromboLYSis for Acute Intermediate-high Risk Acute Pulmonary Embolism
ClinicalTrials.gov study NCT03988842. IPD Sharing: NO. Countries: 1. Publications: 28.
ULTrasound Accelerated ThrombolysIs of PulMonAry Embolism
ClinicalTrials.gov study NCT01166997. IPD Sharing: Not stated. Countries: 2. Publications: 1.
Acute Venous Thrombosis: Thrombus Removal With Adjunctive Catheter-Directed Thrombolysis
ClinicalTrials.gov study NCT00790335. IPD Sharing: Not stated. Countries: 1. Publications: 14.
Safety and Efficacy of Alteplase When Administered in Chinese Patients With Acute Ischemic Hemispheric Stroke Where Thrombolysis is Initiated Between 3 and 4.5 Hours After Stroke Onset
ClinicalTrials.gov study NCT02930837. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Efficacy and Safety of Nerinetide in Participants With Acute Ischemic Stroke Undergoing Endovascular Thrombectomy Excluding Thrombolysis
ClinicalTrials.gov study NCT04462536. IPD Sharing: Not stated. Countries: 9. Publications: 1.
Thrombolysis Versus Primary Angioplasty for AMI in Elderly Patients
ClinicalTrials.gov study NCT00257309. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Submassive and Massive Pulmonary Embolism Treatment With Ultrasound Accelerated Thrombolysis Therapy
ClinicalTrials.gov study NCT01513759. IPD Sharing: Not stated. Countries: 1. Publications: 2.
The Stabilization Of pLaques usIng Darapladib-Thrombolysis In Myocardial Infarction 52 Trial
ClinicalTrials.gov study NCT01000727. IPD Sharing: YES. Countries: 36. Publications: 5.
Safety of Intravenous Thrombolysis for Wake-up Stroke
ClinicalTrials.gov study NCT01183533. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Multi-arm Optimization of Stroke Thrombolysis
ClinicalTrials.gov study NCT03735979. IPD Sharing: NO. Countries: 1. Publications: 6.
Thrombolysis in Pediatric Stroke (TIPS)
ClinicalTrials.gov study NCT01591096. IPD Sharing: NO. Countries: 2. Publications: 2.
The Akershus Study of Ischemic Stroke and Thrombolysis -1
ClinicalTrials.gov study NCT05378490. IPD Sharing: UNDECIDED. Countries: 1. Publications: 5.
Hypothermia in Acute Stroke With Thrombolysis Imaging Evaluation of Revascularization
ClinicalTrials.gov study NCT01778855. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Dapagliflozin and Effect on Cardiovascular Events in Acute Heart Failure -Thrombolysis in Myocardial Infarction 68 (DAPA ACT HF-TIMI 68)
ClinicalTrials.gov study NCT04363697. IPD Sharing: NO. Countries: 1. Publications: 2.
Comparison Between Thrombolysis and Primary Percutaneous Coronary Intervention (PCI) to Treat ST-Segment Elevation Myocardial Infarction
ClinicalTrials.gov study NCT00806403. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Escalating Clopidogrel by Involving a Genetic Strategy - Thrombolysis In Myocardial Infarction 56
ClinicalTrials.gov study NCT01235351. IPD Sharing: Not stated. Countries: 1. Publications: 3.
A Study of Intravenous Thrombolysis With Alteplase in MRI-Selected Patients
ClinicalTrials.gov study NCT01282242. IPD Sharing: NO. Countries: 1. Publications: 2.
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International Brain Laboratory public data
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OpenNeuro
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