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21 results for “thymol”
Data for: Possible synergistic effects of thymol and nicotine against Crithidia bombi parasitism in bumble bees
<p>Data and R scripts for analysis of nicotine-thymol synergy experiment and thymol dose experiment evaluating effects of nectar secondary metabolite treatments on <em>Crithidia bombi </em>parasite load and mortality in the bumble bee <em>Bombus impatiens.</em></p>
Fig. 5 in Are thymol, rosefuran, terpinolene and umbelliferone good scavengers of peroxyl radicals?
Fig. 5. PH effect on the SPLET mechanism rate coefficients of the reaction of Umb and Thy with HOO• in water.
Fig. 4 in Are thymol, rosefuran, terpinolene and umbelliferone good scavengers of peroxyl radicals?
Fig. 4. The acid dissociation equilibrium of the phenolic compounds Thy and Umb in aqueous solution (pH = 7.4).
Fig. 3 in Are thymol, rosefuran, terpinolene and umbelliferone good scavengers of peroxyl radicals?
Fig. 3. Optimized transition states and imaginary frequency (IF) of the reactions of the studied compounds with HOO• in the gas phase. Distances are in Aand angels in ◦.
Fig. 3. a in Sequencing and variation of terpene synthase gene (TPS2) as the major gene in biosynthesis of thymol in different Thymus species
Fig. 3. a. Maximum likelihood tree of Thymus species based on 16 sequences of the TPS of cDNA. Numbers above branches are support values from bootstrap resembling. Accession numbers of TPS2 sequences obtained from the NCBI GenBank are shown in parentheses (Accession numbers starting with MH were obtained through this study). For the studied species, the main monoterpenes in the essential oil are included T: Thymol; C: Carvacrol; PC: p-Cymene; AT: α-Terpineol; L: Linalool. b. Dendrogram of nine studied Thymus species using Ward clustering method based on Tohidi et al. (2017).
Fig. 2 in Sequencing and variation of terpene synthase gene (TPS2) as the major gene in biosynthesis of thymol in different Thymus species
Fig. 2. Amino acid alignment of Ttps2 sequences of nine studied Thymus species. The four motifs, conserved in all species terpene synthases, are indicated in red (top). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Fig. 1 in Sequencing and variation of terpene synthase gene (TPS2) as the major gene in biosynthesis of thymol in different Thymus species
Fig. 1. Predicted biosynthetic pathway of terpene synthases in Thymus genus leading to the formation of α-terpineol and γ-terpinene, the precursor of thymol and carvacrol Adapted from Lima et al. (2013).
Thymol on Netrin-1 on Obese Patients
ClinicalTrials.gov study NCT05427721. IPD Sharing: NO. Countries: 1. Publications: 17.
Figure 1 from: Fouad AA, Moussa NA, Kareem MMA, Akl UI, Abdelghany MI, Abdel-Aziz AM (2022) Thymol exerts antioxidant, anti-inflammatory, and anti-apoptotic protective effects against gentamicin nephrotoxicity in rats. Pharmacia 69(1): 181-186. https://doi.org/10.3897/pharmacia.69.e77338
Figure 1 Results of thymol (TML) on: A. Serum creatinine and neutrophil gelatinase-associated lipocalin (NGAL); B. Renal malondialdehyde (MDA), nitric oxide (NO), and total antioxidant capacity (TAC); C. Renal tumor necrosis factor-α (TNF-α) and interleukin-18 (IL-18); D. Renal Bax; E. Renal caspase-3, and caspase-9 in gentamicin (GN)-challenged rats. Results are mean ± S.E.M., *p < 0.05 vs. control, ≠p < 0.05 vs GN.
Figure 2 from: Fouad AA, Moussa NA, Kareem MMA, Akl UI, Abdelghany MI, Abdel-Aziz AM (2022) Thymol exerts antioxidant, anti-inflammatory, and anti-apoptotic protective effects against gentamicin nephrotoxicity in rats. Pharmacia 69(1): 181-186. https://doi.org/10.3897/pharmacia.69.e77338
Figure 2 H&E (200×) of rat kidneys of: A. Control showing normal renal architecture; B. Gentamicin (GN) group demonstrating marked distortion of kidney architecture, renal tubular necrosis and dilatation, desquamation of lining epithelium (white arrow), cytoplasmic vacuolization (black arrow), interstitial edema, coagulative necrosis (black head), and inflammatory cell infiltration (white head); C. Thymol (TML) + GN showing preservation of the normal kidney histological picture; D. Score of tubular injury. Results are mean ± S.E.M., *p < 0.05 vs. control, ≠p < 0.05 vs. GN.
Figure 4 from: Fouad AA, Moussa NA, Kareem MMA, Akl UI, Abdelghany MI, Abdel-Aziz AM (2022) Thymol exerts antioxidant, anti-inflammatory, and anti-apoptotic protective effects against gentamicin nephrotoxicity in rats. Pharmacia 69(1): 181-186. https://doi.org/10.3897/pharmacia.69.e77338
Figure 4 Immunohistochemistry (200×) of kidney injury molecule-1 (KIM-1) of rat kidneys of: A. Control showing no staining (NS); B. Gentamicin (GN) group demonstrating a significant increment of KIM-1 immunopositivity in brown color; C. Thymol (TML) + GN showing a significant decrement of KIM-1 immunoreactivity; D. Immunoreactive area (µm2). Results are mean ± S.E.M., *p < 0.05 vs. control, ≠p < 0.05 vs. GN.
Figure 3 from: Fouad AA, Moussa NA, Kareem MMA, Akl UI, Abdelghany MI, Abdel-Aziz AM (2022) Thymol exerts antioxidant, anti-inflammatory, and anti-apoptotic protective effects against gentamicin nephrotoxicity in rats. Pharmacia 69(1): 181-186. https://doi.org/10.3897/pharmacia.69.e77338
Figure 3 Immunohistochemistry (200×) of nuclear factor-κB p65 (NF-κB p65) of rat kidneys of: A. Control showing no staining (NS); B. Gentamicin (GN) group demonstrating a significant increment of NF-κB p65 immunopositivity in brown color; C. Thymol (TML) + GN showing a significant decrement of NF-κB p65 immunoreactivity; D. Immunoreactive area (µm2). Results are mean ± S.E.M., *p < 0.05 vs. control, ≠p < 0.05 vs. GN.
Fig. 1 in Are thymol, rosefuran, terpinolene and umbelliferone good scavengers of peroxyl radicals?
Fig. 1. Molecular structure and atomic numbering of the investigated essential oil constituents.
Transcriptomic response in the skin of gilthead sea bream (Sparus aurata) fed garlic, carvacrol and thymol essential oils (EOs) additive
GEO Series GSE162504. Sparus aurata. 6 samples. Type: Expression profiling by array.
Potentiating the activity of berberine for Staphylococcus aureus in a combinatorial treatment with thymol
GEO Series GSE138090. Staphylococcus aureus. 2 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomic response in gills of gilthead sea bream (Sparus aurata) fed garlic, carvacrol and thymol essential oils (EOs) additive
GEO Series GSE144055. Sparus aurata. 6 samples. Type: Expression profiling by array.
Transcriptomic response in the intestine of gilthead sea bream (Sparus aurata) fed garlic, carvacrol and thymol essential oils (EOs) additive.
GEO Series GSE159643. Sparus aurata. 6 samples. Type: Expression profiling by array.
A Study to Evaluate the Effect and Tolerance of Musclin™ (Thymol) in Healthy Subjects
ClinicalTrials.gov study NCT03767504. IPD Sharing: NO. Countries: 1. Publications: 0.
Global transcriptional profiling of Saccharomyces cerevisiae treated with thymol
GEO Series GSE12329. Saccharomyces cerevisiae. 3 samples. Type: Expression profiling by array.
Fig. 2 in Are thymol, rosefuran, terpinolene and umbelliferone good scavengers of peroxyl radicals?
Fig. 2. Optimized molecular structures (a), frontier molecular orbitals (b), and molecular electrostatic potentials (c) of the studied compounds computed at M05-2X/ 6–311++ G(d,p) level of theory in the gas phase. For the molecular electrostatic potentials, a deep red color indicates an electron-rich site, whereas deep blue indicates an electron-deficient site. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)
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