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Dataset results
17 results for “toxicological assessment”
Figure 1 in Integrative analysis in toxicological assessment of the insecticide Malathion in Allium cepa L. system
Figure 1. Rates of alterations found for Allium cepa cells exposed for 48h to distilled water (H O – negative control), 0.5 mg mL-1, 2 d 1.0 mg mL-1 of Malathion and methyl methanesulfonate (MMS – positive control), concerning: (A) anaphase bridge; (B) chromosome loss; (C) chromosome delay; (D) micronuclei index. KW-H = results of Kruskal-Wallis test and p = value of the statistical probability. Letters on the error bars indicate the result of the statistical Mann-Whitney U test.
Figure 3 in Integrative analysis in toxicological assessment of the insecticide Malathion in Allium cepa L. system
Figure 3. Discriminant canonical function, showing the distribution of the centroids e of the groups of the different treatments; 1: treatment submitted to distilled water; 4: positive control with MMS; 2 and 3: groups exposed to Malathion, for 0.5 e 1.0 mg mL-1 concentrations, respectively.
Figure 2 in Integrative analysis in toxicological assessment of the insecticide Malathion in Allium cepa L. system
Figure 2. Mitotic index at the radicular meristematic region of Allium cepa cells, after exposure for 48 hours to distilled water (H Od – negative control), 0.5 mg mL-1, 1.0 mg mL-1 of Malathion 2 and methyl methanesulfonate (MMS – positive control). KW-H = results of Kruskal-Wallis test and p = value of the statistical probability. Letters on the error bars indicate the result of the statistical Mann-Whitney U test.
Fig 1A in Toxicological assessments of basic blue 3 dye in fresh water bivalve Lamellidens marginalis
Fig 1A: Section passing through gill of fresh water bivalve Lamellidensmarginalisfrom control group (400X). B: Effect of 40 ppm (LC0) of Basic Blue 3 on gill of fresh water bivalve Lamellidensmarginalis after 96 hours exposure (400X) C: Effect of 70 ppm (LC50) of Basic Blue 3 on gill of fresh water bivalve Lamellidenmarginalis after 96 hours exposure (400X)
Fig 2A in Toxicological assessments of basic blue 3 dye in fresh water bivalve Lamellidens marginalis
Fig 2A: Section passing through hepatopancreas of fresh water bivalve Lamellidens marginalis from control group (400X). B: Effect of 40 ppm (LC0) of Basic Blue 3 on hepatopancreas of fresh water bivalve Lamellidens marginalis after 96 hours exposure (400X) C: Effect of 70 ppm (LC50) of Basic Blue 3 on hepatopancreas of fresh water bivalve Lamellidens marginalis after 96 hours exposure (400X)
Fig 4A in Toxicological assessments of basic blue 3 dye in fresh water bivalve Lamellidens marginalis
Fig 4A: Photomicrogragh of gill cell of Lamellidens marginalis for 96 hours exposure; degree of damage class 0 B: Photomicrogragh of gill cell of Lamellidens marginalis for 96 hours exposure to 40 ppm concentration of Basic blue 3; degree of damage class 0 C: Photomicrogragh of gill cell of Lamellidens marginalis for 96 hours exposure to 70 ppm concentration of Basic blue 3; degree of damage class I
Fig 3A in Toxicological assessments of basic blue 3 dye in fresh water bivalve Lamellidens marginalis
Fig 3A: Section passing through gonad of fresh water bivalve Lamellidens marginalis from control group (400X). B: Effect of 40 ppm (LC0) of Basic Blue 3 on gonad of fresh water bivalve Lamellidens marginalis after 96 hours exposure (400X) C: Effect of 70 ppm (LC50) of Basic Blue 3 on gonad of fresh water bivalve Lamellidens marginalis after 96 hours exposure (400X)
Graph 1 in Toxicological assessments of basic blue 3 dye in fresh water bivalve Lamellidens marginalis
Graph 1: Changes in SODactivity in different tissues of fresh water bivalve, Lamellidens marginalis after acute exposure to basic blue 3(values are expressed in unit/mg protein/hour)
Graph 4 in Toxicological assessments of basic blue 3 dye in fresh water bivalve Lamellidens marginalis
Graph 4: DNA strand breaks in gill cells of Lamellidens marginalis after acute exposure to Basic blue 3.
Graph 2 in Toxicological assessments of basic blue 3 dye in fresh water bivalve Lamellidens marginalis
Graph 2: Changes in CAT activity in different tissues of fresh water bivalve, Lamellidens marginalis after acute exposure to basic blue 3 (values are inmmolH2O2/min/mg protein)
Graph 3 in Toxicological assessments of basic blue 3 dye in fresh water bivalve Lamellidens marginalis
Graph 3: Changes in GPx activityin different tissues of fresh water bivalve, Lamellidens marginalis after acute exposure to basic blue 3 (values are in mmol NADPH/min/mg protein)
Toxicological Effect and Risk Assessment (TERA) Knowledge Graph
<p>The Toxicological Effect and Risk Assessment (TERA) Knowledge Graph is based on chemical effect data from U.S. EPA ECOTOX. This data is aligned to non-proprietary identifiers using ontology alignment tools and external sources (eg. wikidata). This enables the use of external chemical knowledge graphs (eg. ChEBI, PubChem, Mesh, "Courtesy of the U.S. National Library of Medicine"). This data set also included an aggregated (into a knowledge graph) of the NCBI taxonomy and Encyclopedia of Life traits data. </p> <p>Linking ECOTOX to external sources enables the extrapolation of effect data, which can extend the reach of ecological risk assessment and limit laboratory experiments. </p> <p>The construction and APIs to facilitate access can be found at <a href="https://gitlab.com/Erik-BM/rappt">https://github.com/NIVA-Knowledge-Graph/TERA</a> </p> <p> </p> <p>LICENCES:<br> <strong>EOL</strong>: Various Creative Commons (CC),<br> <strong>NCBI</strong>: Creative Commons CC0 1.0 Universal (CC0 1.0),<br> <strong>ECOTOX</strong>: No restrictions,<br> <strong>PubChem</strong>: Open Data Commons Open Database License, <br> <strong>ChEMBL</strong>: CC Attribution,<br> <strong>MeSH</strong>: Open<em>, Courtesy of the U.S. National Library of Medicine,</em><br> <strong>Wikidata</strong><em>: CC0 1.0.</em></p> <p> </p>
Raw NMR and GC reports for the article Electrochemical Hydrogenation of Alkenes over a Nickel Foam Guided by Life Cycle, Safety and Toxicological Assessments, Green Chemistry, doi: https://doi.org/10.1039/D4GC02924K
<p>Raw NMR for the article Electrochemical Hydrogenation of Alkenes over a Nickel Foam Guided by Life Cycle, Safety and Toxicological Assessments, Green Chemistry, doi: https://doi.org/10.1039/D4GC02924K</p> <p>The raw NMR data files for all compounds reported in the article are included. The numbering corresponds to those in the article.</p> <p>Each parent folder contains subfolders with different files. In order to process this data, the full parent folder must be dragged into either Mestrenova or Topspin and then the data is automatically processed. If the name of the raw data files are renamed, the software (<a href="https://mestrelab.com/" target="_blank" rel="noopener noreferrer">Mestrenova</a> or <a href="https://www.bruker.com/en/products-and-solutions/mr/nmr-software/topspin.html" target="_blank" rel="noopener noreferrer">Topspin</a>) will not be able to process the files</p> <p> </p>
Qualifying a human Liver-Chip for predictive toxicology: Performance assessment and economic implications
GEO Series GSE207339. Homo sapiens. 22 samples. Type: Expression profiling by high throughput sequencing.
Multiomics profiling of zebrafish embryonic cell line PAC2 across growth phases to assess its relevance for toxicological studies
GEO Series GSE303229. Danio rerio. 7 samples. Type: Expression profiling by high throughput sequencing.
Evaluating the utility of the Threshold of Toxicological Concern (TTC) and its exclusions in the biocompatibility assessment of extractable chemical substances from medical devices
<p>Data supporting manuscript Patlewicz G, Nelms M, Rua D. Evaluating the utility of the Threshold of Toxicological Concern (TTC) and its exclusions in the biocompatibility assessment of extractable chemical substances from medical devices. Computational Toxicology, 2022, in press <a href="https://doi.org/10.1016/j.comtox.2022.100246" rel="nofollow">https://doi.org/10.1016/j.comtox.2022.100246</a></p>
Development of Chemical Categories for Per- and Polyfluoroalkyl Substances (PFAS) and the Proof-of-Concept Approach to the Identification of Potential Candidates for Tiered Toxicological Testing and Human Health Assessment
<p>Supplementary information for the manuscript and raw data files underpinning the analysis are available here as compressed tar files. </p> <p>Please cite: Patlewicz G., Judson R., Williams A. J., Butler T., Barone Jr. S ., Carstens K. E., Cowden J., Dawson J. L., Degitz S. , Fay K., Henry T. R., Lowit A., Padilla S., Paul Friedman K., Phillips M. B., Turk D., Wambaugh J., Wetmore B., Thomas R.S. Development of Chemical Categories for Per- and Polyfluoroalkyl Substances (PFAS) and the Proof-of-Concept Approach to the Identification of Potential Candidates for Tiered Toxicological Testing and Human Health Assessment. <em>Computational Toxicology</em> <strong>2024</strong> <a href="https://doi.org/10.1016/j.comtox.2024.100327" rel="nofollow">https://doi.org/10.1016/j.comtox.2024.100327</a></p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.