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38 results for “transformation pathway”

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zenodo36/100

Pathformer: a biological pathway informed Transformer for disease diagnosis and prognosis using multi-omics data

<p>Integrating multi-omics data offers a more comprehensive view of gene regulation, which would be helpful in achieving accurate diagnosis of diseases like cancer. To improve the accuracy of disease diagnosis and prognosis, we developed Pathformer, a multi-omics integration method for both tissue and liquid biopsy data. We implemented Pathformer's network architecture using the &ldquo;PyTorch&rdquo; package in Python v3.6.9, and our codes can be found in the GitHub repository (https://github.com/lulab/Pathformer). This repository contains preprocessed TCGA dataset data, preprocessedliquid biopsy dataset data, result of Pathformer and comparison_methods, mentioned in GitHub project and article.</p>

openmit-licenseDec 2023View details →
zenodo36/100

Case study input data set for article "Stochastic planning of energy system transformation pathways under uncertain industry demands"

<p>The data set contains input data for the model EMPRISE of Fraunhofer Institute for Energy Economics and Energy System Technology IEE.&nbsp;</p>

opencc-by-4.0May 2024View details →
zenodo32/100

An assessment of energy system transformation pathways to achieve net-zero carbon dioxide emissions in Switzerland. Supplementary Information Assumptions and Results

<p>This dataset accompanies the corresponding article in Communications Earth and Environment. It contains the key assumptions used in the energy system modelling with the Swiss TIMES energy systems model (STEM) for assessing net-zero carbon dioxide emissions scenarios for Switzerland. In addition, contains extensive results from STEM for each one of the core scenarios and variants assessed in the study.</p> <p>The following files are contained in this repository:</p> <ul> <li><strong>Supplementary Data 1</strong>: This is the EXCEL file &quot;Supplementary_Information_Assumptions.xslx&quot; which contains key assumptions of the long-term scenarios assessed with STEM. These include among others: the major energy and climate policies in each scenario, the economic and demographic assumptions, key drivers for the residential energy demand (e.g., floor reference area or appliances), key drivers for the energy demand in the services sectors (e.g., Gross Value Added or floor area), key drivers for the energy demand in industry (e.g., production index or Gross Value Added), mobility demands, energy import prices, hourly electricity import prices, net transfer capacities, domestic sustainable renewable resource potentials, energy supply and demand technologies costs and efficiencies</li> <li><strong>Supplementary Data 2</strong>: This is the EXCEL file &quot;Supplementary_Information_Results.xlsx&quot; which contains energy balances from the baseline and the net-zero CO<sub>2</sub> emissions scenarios. The results for each scenario are:&nbsp;domestic production by fuel, net imports by fuel, primary energy consumption by fuel, input to conversion sectors by fuel, electricity supply and capacities by fuel, district heating supply by fuel, final energy consumption by fuel and sector, CO2 emissions by source, energy system costs, and indicators such as energy consumption per capita, energy intensity of GDP, CO2 emissions per capita and CO2 intensity of GDP.&nbsp;</li> <li><strong>Supplementary Data 3</strong>:&nbsp;The ZIP file &quot;Source_code_and_data_for_charts.zip&quot; contains source codes and data for reproducing the figures in the manuscript.&nbsp;</li> </ul>

opencc-by-4.0Mar 2023View details →
ClinicalTrials.gov28/100

Pathways to Equitable Access to Kidney Transplantation in Spain: A Transformative Mixed-methods Study Protocol

ClinicalTrials.gov study NCT07208994. IPD Sharing: YES. Countries: 1. Publications: 0.

controlledIPD-YESFeb 2026View details →
geo24/100

Transcriptome profiling of the interconnection of pathways involved in malignant transformation and response to hypoxia

GEO Series GSE109367. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMay 2018View details →
geo24/100

fiber transformation without CaMK pathway in electric-stimulation

GEO Series GSE6660. Mus musculus. 18 samples. Type: Expression profiling by array.

openGEO-OpenJan 2007View details →
geo24/100

Identification of transformation-related pathways in a breast epithelial cell model using a ribonomics approach.

GEO Series GSE12215. Homo sapiens. 12 samples. Type: Expression profiling by array.

openGEO-OpenJul 2008View details →
geo24/100

Diethyl maleate inhibits MCA+TPA transformed cell growth via modulation of GSH, MAPK, and cancer pathways

GEO Series GSE44650. Mus musculus. 4 samples. Type: Expression profiling by array.

openGEO-OpenJun 2014View details →
geo24/100

Dysregulation of pathways involved in the processing of cancer and microenvironment information in MCA+TPA transformed C3H/10T1/2 cells

GEO Series GSE41142. Mus musculus. 4 samples. Type: Expression profiling by array.

openGEO-OpenApr 2013View details →
geo24/100

RNA-Seq analysis of genes and pathways involved in the TGF-β-driven transformation of fibroblasts to myofibroblasts

GEO Series GSE110021. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2020View details →
geo24/100

Transcriptomic alterations including p53 pathway dysregulation prime DNMT3A mutant cells for transformation

GEO Series GSE275532. Mus musculus. 13 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJun 2025View details →
geo24/100

Lurbinectedin is an effective therapeutic target for de novo and transformed small cell lung cancer and modulates EMT and NOTCH signaling pathways. 

GEO Series GSE223372. Homo sapiens. 61 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJun 2023View details →
geo24/100

KLK1 prevents colorectal inflammation-cancer transformation via B1R-mediated ECM pathway

GEO Series GSE282383. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2025View details →
geo24/100

Identification of deregulated pathways, key regulators, and novel miRNA-mRNA interactions in HPV-mediated transformation. [CGH cell lines-Agilent]

GEO Series GSE138724. Homo sapiens. 32 samples. Type: Genome variation profiling by genome tiling array.

openGEO-OpenApr 2020View details →
geo24/100

Distinct GAB2 signaling pathways are essential for myeloid and lymphoid transformation and leukemogenesis by BCR-ABL1

GEO Series GSE75615. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2016View details →
geo24/100

MircroRNA-92b, a Novel Negative Regulator of the Transforming Growth Factor-β Signaling Pathway Targeting the Type I Receptor

GEO Series GSE242295. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2023View details →
geo24/100

Systems-level analyses reveal a convergent pathway for progression of diffuse astrocytoma and potential role for resveratrol in delaying high-grade transformation

GEO Series GSE117620. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2019View details →
geo24/100

fiber transformation with activation of CaN pathway

GEO Series GSE6658. Mus musculus. 6 samples. Type: Expression profiling by array.

openGEO-OpenJan 2007View details →
ClinicalTrials.gov24/100

Transforming Ovarian Cancer Diagnostic Pathways

ClinicalTrials.gov study NCT06129968. IPD Sharing: NO. Countries: 1. Publications: 0.

closedIPD-NOFeb 2026View details →
geo24/100

Differential Network Analysis Reveals the Key Role of the ECM-receptor Pathway in α-Particle-induced Malignant Transformation

GEO Series GSE235882. Homo sapiens. 21 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2023View details →

ScienceDex guides

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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

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Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record

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