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78 results for “translational selection”
Post-Translational Site-selective Protein Backbone α-Deuteration
<p>This folder TS_xyz contains all the TS structures from conformational sampling in .xyz format accompanying the paper</p> <p>"Post-Translational Site-selective Protein α-Deuteration: Protein Backbone Modification and Use as a Tool for Protein Mechanism" by Galan et al.</p> <p><br> Two subfolders, indicated by the identity of the base used int the studies, with the following substructures, can be found:</p> <p> <br> |------ THTCD_deprotonation: all TSs from deprotonation of tetrahydrothiophene ring<br> | <br> 1_hydroxide_base --------|------ intramolecular deprotonation: all TSs from intramolecular deprotonation by sulfonium ylid<br> |<br> |------ E2_deprotonation: all TSs from deprotonation of alpha-carbon of cysteine<br> |<br> |------ sulfonium_ylid_deprotonation: all TSs from sulfonium ylid decomposition via cycloreversion</p> <p> |------ THTCD_deprotonation: lowest (and the only found) TS for deprotonation of tetrahydrothiophene ring <br> | <br> 2_dihydrogen_phosphate_base --------|<br> |<br> |------ E2_deprotonation: all TSs from deprotonation of alpha-carbon of cysteine<br> </p>
Data from: Translational selection frequently overcomes genetic drift in shaping synonymous codon usage patterns in vertebrates
Synonymous codon usage (SCU) patterns are shaped by a balance between mutation, drift, and natural selection. To date, detection of translational selection in vertebrates has proven to be a challenging task, obscured by small long-term effective population sizes in larger animals and the existence of isochores in some species. The consensus is that, in such species, natural selection is either completely ineffective at overcoming mutational pressures and genetic drift or perhaps is effective but so weak that it is not detectable. The aim of this research is to understand the interplay between mutation, selection, and genetic drift in vertebrates. We observe that although variation in mutational bias is undoubtedly the dominant force influencing codon usage, translational selection acts as a weak additional factor influencing synonymous codon usage. These observations indicate that translational selection is a widespread phenomenon in vertebrates and is not limited to a few species.
Data from: Translational selection frequently overcomes genetic drift in shaping synonymous codon usage patterns in vertebrates
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Selective stalling of human translation through small molecule engagement of the ribosome nascent chain
GEO Series GSE94454. Homo sapiens. 26 samples. Type: Other; Expression profiling by high throughput sequencing.
Enhanced and selective translation expands the lysosome size and promotes antigen presentation during phagocyte activation
GEO Series GSE136470. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
Allele-selective Transcriptome Recruitment to Polysomes Primed for Translation: Protein-coding and Noncoding RNAs, and RNA Isoforms
GEO Series GSE66135. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing; Genome variation profiling by high throughput sequencing.
MAEL-dependent selective processing of pachytene piRNA precursors and translation of spermiogenic mRNAs
GEO Series GSE50983. Mus musculus. 17 samples. Type: Non-coding RNA profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Sequence selectivity of macrolide-induced translational regulation
GEO Series GSE57175. Staphylococcus aureus subsp. aureus NCTC 8325. 12 samples. Type: Expression profiling by high throughput sequencing.
Identification of a LncRNA EPR—>METTL7A1 pathway modulating translation of select genes (Polysomes)
GEO Series GSE195821. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Selective ribosome profiling reveals the co-translational chaperone action of trigger factor in vivo
GEO Series GSE33671. Escherichia coli. 8 samples. Type: Expression profiling by high throughput sequencing.
Classification by a gene expression profile can help to select oxaliplatin- or irinotecan-based regimen for first-line treatment of metastatic colorectal cancer: Translational research of the TRICOLOR
GEO Series GSE147571. Homo sapiens. 308 samples. Type: Expression profiling by array.
Pateamine A mediates RNA sequence-selective translation repression by anchoring eIF4A and DDX3 to GNG motifs
GEO Series GSE243312. Homo sapiens; synthetic construct. 36 samples. Type: Expression profiling by high throughput sequencing; Other.
Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons
GEO Series GSE135338. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing; Other.
A p53-dependent translational program directs tissue-selective phenotypes in a model of ribosomopathies
GEO Series GSE135722. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing; Other.
High-resolution Ribosome Profiling Reveals Translational Selectivity in Bovine Preimplantation Embryo Development
GEO Series GSE196484. Bos taurus. 138 samples. Type: Expression profiling by high throughput sequencing; Other.
Selective Translation Complex Profiling in yeast and human Reveals Staged Initiation and Co-translational Assembly of Initiation Factor Complexes [Yeast]
GEO Series GSE139130. Saccharomyces cerevisiae. 16 samples. Type: Expression profiling by high throughput sequencing; Other.
Translational fidelity screens reveal eIF3 as a key regulator of start codon selectivity [RNA-seq]
GEO Series GSE207330. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing.
Distinct modes of non-canonical initiation regulate selective host versus viral mRNA translation during poxvirus-induced shutoff
GEO Series GSE278320. Homo sapiens. 38 samples. Type: Other.
Selective Translation Complex Profiling in yeast and human Reveals Staged Initiation and Co-translational Assembly of Initiation Factor Complexes [Human]
GEO Series GSE139131. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing; Other.
Gemin5-dependent RNA association to polysomes supports selective translation of mRNA subsets
GEO Series GSE200388. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing; Other.
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