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19 results for “vaccination method”
DATASET Skin-Based Vaccination: A Systematic Mapping Review of the Types of Vaccines and Methods Used and Immunity and Protection Elicited in Pigs
<p>Dataset listing all publications used in systematic mapping review. This file contains the dataset, a dictionary and values worksheets for the following publication: </p> <p>Skin-Based Vaccination: A Systematic Mapping Review of the Types of Vaccines and Methods Used and Immunity and Protection Elicited in Pigs.</p> <p>Vaccines 2023</p> <p><a href="https://pubmed.ncbi.nlm.nih.gov/?sort=date&size=200&term=C%C3%B3-Rives+I&cauthor_id=36851328">Inés Có-Rives</a> <a href="https://pubmed.ncbi.nlm.nih.gov/36851328/#full-view-affiliation-1">1</a>, <a href="https://pubmed.ncbi.nlm.nih.gov/?sort=date&size=200&term=Chen+AY&cauthor_id=36851328">Ann Ying-An Chen</a> <a href="https://pubmed.ncbi.nlm.nih.gov/36851328/#full-view-affiliation-1">1</a>, <a href="https://pubmed.ncbi.nlm.nih.gov/?sort=date&size=200&term=Moore+AC&cauthor_id=36851328">Anne C Moore</a> <a href="https://pubmed.ncbi.nlm.nih.gov/36851328/#full-view-affiliation-1">1</a></p> <ul> <li>PMID: 36851328</li> <li>PMCID: <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/pmc9962282/">PMC9962282</a></li> <li>DOI: <a href="https://doi.org/10.3390/vaccines11020450">10.3390/vaccines11020450</a></li> </ul> <p>The advantages of skin-based vaccination include induction of strong immunity, dose-sparing, and ease of administration. Several technologies for skin-based immunisation in humans are being developed to maximise these key advantages. This route is more conventionally used in veterinary medicine. Skin-based vaccination of pigs is of high relevance due to their anatomical, physiological, and immunological similarities to humans, as well as being a source of zoonotic diseases and their livestock value. We conducted a systematic mapping review, focusing on vaccine-induced immunity and safety after the skin immunisation of pigs. Veterinary vaccines, specifically anti-viral vaccines, predominated in the literature. The safe and potent skin administration to pigs of adjuvanted vaccines, particularly emulsions, are frequently documented. Multiple methods of skin immunisation exist; however, there is a lack of consistent terminology and accurate descriptions of the route and device. Antibody responses, compared to other immune correlates, are most frequently reported. There is a lack of research on the underlying mechanisms of action and breadth of responses. Nevertheless, encouraging results, both in safety and immunogenicity, were observed after skin vaccination that were often comparable to or superior the intramuscular route. Further research in this area will underlie the development of enhanced skin vaccine strategies for pigs, other animals and humans.</p> <p><strong>Keywords: </strong>epicutaneous; epidermal; intradermal; needle-free; percutaneous; pig; skin; transcutaneous; transdermal; vaccine.</p>
Looking in the medicine cabinet: methods for using real-world data to assess the impact of measles, mumps and rubella (MMR) and recombinant adjuvanted varicella-zoster vaccines on coronavirus disease 2019 (COVID-19) prevention and case fatality
<p>Supplementary File S1. 20210712_vx_off_target_pubdraft_S1 (Tables, Graphs and scripts associated with publication)</p> <p>Data file 1. Basic_Analysis.R (descriptive analysis script in R, for use with cleaned data files 3, 4 and 6)<br> Data file 2. Cleaning (Script demonstrating how Cerner data was cleaned upon download)<br> Data file 3. COVID_all_cleaned (CSV file with all COVID+ subjects in Cerner institutions)<br> Data file 4. COVID_mmr_data_cleaned (CSV file with COVID+ patients between 25-64 years old, including institution id, age category, gender, whether patient is in emergency department or inpatient, flu vaccine history, MMR vaccine history and mortality outcomes)<br> Data file 5. COVID_mmr_data_matched (CSV file matching MMR vaccine-exposed cases to controls based on propensity scores)<br> Data file 6. COVID_zoster_data_cleaned (CSV file with COVID+ patients above 50 years old, including institution id, age category, gender, whether patient is in emergency department or inpatient, flu vaccine history, zoster vaccine history and mortality outcomes)<br> Data file 7. COVID_zoster_data_matched (CSV file matching zoster vaccine-exposed cases to controls based on propensity scores)<br> Data file 8. General_25_64_data_cleaned (CSV file, all patients in Cerner institutions between 25 – 64 years old, including institution id, age category, gender, whether patient is in emergency department or inpatient, flu vaccine history, MMR vaccine history, SARS-CoV-2 infection and COVID-19 mortality outcomes ).<br> Data file 9. General_over50_data_cleaned (CSV file, all patients in Cerner institutions above 50 years old, including institution id, age category, gender, whether patient is in emergency department or inpatient, flu vaccine history, zoster vaccine history, SARS-CoV-2 infection and COVID-19 mortality outcomes).<br> Data file 10. Included_tenants (CSV file, institution IDs whose contributed cases comprise at least 0.5% of the aggregate sample size).<br> Data file 11. MMR_ps (R script to run for MMR-related files analysis)<br> Data file 12. Zoster_ps (R script to run for zoster-related files analysis)</p>
Effect of Varied Outreach Methods on Appointment Scheduling, Appointment Completion, and Receipt of COVID-19 Vaccination
ClinicalTrials.gov study NCT04904744. IPD Sharing: NO. Countries: 1. Publications: 1.
Vaccine Prevention of Rabies Adopts 4-shot Immunization Method
ClinicalTrials.gov study NCT05549908. IPD Sharing: YES. Countries: 1. Publications: 1.
Trial23 - A Method Study on Cervical Screening in Women Offered HPV-vaccination as Girls
ClinicalTrials.gov study NCT03049553. IPD Sharing: NO. Countries: 1. Publications: 3.
Comparison of Different Methods for Reducing Pain From Influenza Vaccine Injections
ClinicalTrials.gov study NCT01006187. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Data from: Evaluation of the first pharmacist-administered vaccinations in Western Australia: a mixed-methods study
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Data from: Vaccination method affects immune response and bacterial growth but not protection in the Salmonella Typhimurium animal model of typhoid
Understanding immune responses elicited by vaccines, together with immune responses required for protection, is fundamental to designing effective vaccines and immunisation programs. This study examines the effects of the route of administration of a live attenuated vaccine on its interactions with, and stimulation of, the murine immune system as well as its ability to increase survival and provide protection from colonisation by a virulent challenge strain. We assess the effect of administration method using the murine model for typhoid, where animals are infected with S. Typhimurium. Mice were vaccinated either intravenously or orally with the same live attenuated S. Typhimurium strain and data were collected on vaccine strain growth, shedding and stimulation of antibodies and cytokines. Following vaccination, mice were challenged with a virulent strain of S. Typhimurium and the protection conferred by the different vaccination routes was measured in terms of challenge suppression and animal survival. The main difference in immune stimulation found in this study was the development of a secretory IgA response in orally-vaccinated mice, which was absent in IV vaccinated mice. While both strains showed similar protection in terms of challenge suppression in systemic organs (spleen and liver) as well as survival, they differed in terms of challenge suppression of virulent pathogens in gut-associated organs. This difference in gut colonisation presents important questions around the ability of vaccines to prevent shedding and transmission. These findings demonstrate that while protection conferred by two vaccines can appear to be the same, the mechanisms controlling the protection can differ and have important implications for infection dynamics within a population.
Effect of Varied Outreach Methods on Appointment Scheduling, Appointment Completion, and Receipt of MMR Vaccination
ClinicalTrials.gov study NCT04567342. IPD Sharing: NO. Countries: 1. Publications: 0.
Data from: Vaccination method affects immune response and bacterial growth but not protection in the Salmonella Typhimurium animal model of typhoid
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A whole virion vaccine for COVID-19 produced via a novel inactivation method: results from animal challenge model studies
GEO Series GSE165190. Mesocricetus auratus. 12 samples. Type: Expression profiling by high throughput sequencing.
New Methods to Measure the Immune Response to Hepatitis B Vaccine
ClinicalTrials.gov study NCT01821547. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Effect of Distraction Method on Children's Pain and Fear Levels During Vaccine Administration
ClinicalTrials.gov study NCT06686992. IPD Sharing: NO. Countries: 1. Publications: 0.
Effectiveness of Different Non-pharmacological Methods in Pain Management During Vaccination.
ClinicalTrials.gov study NCT04436185. IPD Sharing: NO. Countries: 1. Publications: 0.
Developing Methods to Investigate Additional Opportunities of HPV Vaccination by Using First-void Urine Samples
ClinicalTrials.gov study NCT04391647. IPD Sharing: NO. Countries: 1. Publications: 0.
The Effect of Mechanical Vibration and Flick Tapping Methods in Reducing Pain in Infant Vaccination
ClinicalTrials.gov study NCT07185152. IPD Sharing: NO. Countries: 1. Publications: 0.
Impact of Adolescent Vaccine Reminder Notices Sent Via Preferred Method of Communication on HPV Vaccination
ClinicalTrials.gov study NCT05148559. IPD Sharing: NO. Countries: 1. Publications: 0.
Non-Pharmacological Methods for Reducing Pain During Vaccination in Infants
ClinicalTrials.gov study NCT06886412. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Effect on Pain and Satisfaction of Two Different Non-Pharmacological Methods Used During Coronavirus (Covid-19) Vaccination
ClinicalTrials.gov study NCT05514262. IPD Sharing: NO. Countries: 0. Publications: 0.
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