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ShareScore release 0.7.1
Dataset results
138 results for “viral hepatitis”
Assessment of hepatitis B viral lymphotrophism using deep curation
<p><strong><span>Background</span></strong><span><strong>:</strong> The replicative forms of the hepatitis B virus (HBV) is found in several types of white blood cells within the host defense system. To determine the dimensionality of the extrahepatic manifestation of HBV in host white blood cells, it is important to understand the complete biology of its pathogenesis and lymphotropic nature.</span></p> <p><strong><span>Methods</span></strong><span><strong>: </strong>Deep curation of the literature from the PubMed database pertaining to the HBV manifestation in the human host white blood cells was conducted and then manually filtered to determine the behavioral trend of the virus within the human white blood cells.</span></p> <p><strong><span>Results</span></strong><span><strong>:</strong> The curation of 198 research articles identified 28 genes, 92 proteins, and 20 Peripheral Blood Mononuclear cells involved in HBV pathogenesis, while 20 immune cells were found to be permissive for the viral penetration and replication. The presence of the replicative forms of HBV in the host immune cells led to the further elucidation of 28 genes and 92 proteins that interact with one or more viral genes and proteins.</span></p> <p><strong><span>Conclusions</span></strong><span><strong>:</strong> A multi-dimensional analysis using deep curation identified a possible lymphotropic character of HBV. Moreover, there are certain pathways that could aid in the propagation of viral infection by using immune cells to its advantage. Thus, instead of eliminating HBV, the immune system may contribute to the population expansion of the virus.</span></p>
Myrcludex B in Combination With Peginterferon Alfa-2a Versus Peginterferon Alfa-2a Alone in Patients With Chronic Viral Hepatitis B With Delta-agent
ClinicalTrials.gov study NCT02888106. IPD Sharing: NO. Countries: 1. Publications: 3.
A Study Evaluating 24-Week and 48-Week Telaprevir-Based Regimen in Treatment Naïve Subjects With Genotype 1 Chronic Hepatitis C Who Achieve an Extended Rapid Viral Response
ClinicalTrials.gov study NCT00758043. IPD Sharing: Not stated. Countries: 4. Publications: 1.
The Effect of Viral Load on Intrahepatic Recurrence in Hepatitis B Virus (HBV)-Related Hepatocellular Carcinoma (HCC)
ClinicalTrials.gov study NCT00397540. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Viral Kinetics Study of Telbivudine and Entecavir in Adults With Chronic Hepatitis B
ClinicalTrials.gov study NCT00412529. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Study To Evaluate Safety and Efficacy of Vesatolimod for the Treatment of Chronic Hepatitis B Virus in Virally-Suppressed Participants
ClinicalTrials.gov study NCT02166047. IPD Sharing: Not stated. Countries: 6. Publications: 2.
Safety and Efficacy of Celecoxib Plus Nucleos(t)Ide Analogues on the Hepatitis B Surface Antigen of Virally Suppressed Subjects With Chronic Hepatitis B
ClinicalTrials.gov study NCT05256823. IPD Sharing: NO. Countries: 1. Publications: 2.
Safety, Tolerability and Antiviral Activity of Selgantolimod in Virally-Suppressed Participants With Chronic Hepatitis B
ClinicalTrials.gov study NCT03491553. IPD Sharing: NO. Countries: 2. Publications: 1.
Efficacy of All-Oral Anti-Viral Therapy for Symptomatic Hepatitis C Virus Infection-Related Cryoglobulinemia
ClinicalTrials.gov study NCT02825212. IPD Sharing: NO. Countries: 1. Publications: 27.
This Trial Evaluates Safety, Pharmacokinetic Profile and Anti-viral Response of BI 207127 and BI 201335 for Patients With Chronic Hepatitis C
ClinicalTrials.gov study NCT01528735. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Study to Test Whether BI 685509 Alone or in Combination With Empagliflozin Helps People With Liver Cirrhosis Caused by Viral Hepatitis or Non-alcoholic Steatohepatitis (NASH) Who Have High Blood Pre
ClinicalTrials.gov study NCT05282121. IPD Sharing: YES. Countries: 16. Publications: 1.
Assessment of hepatitis B viral lymphotrophism using deep curation
Open the record for dataset details and reuse information.
A Multi-Scale Spatial Model of Hepatitis-B Viral Dynamics
<p>Dataset related to an accepted manuscript:</p> <p>A Multi-Scale Spatial Model of Hepatitis-B Viral Dynamic. Cangelosi Q., Means S., Ho H. PLOS One</p> <p>Dataset documented in a ReadMe file.</p>
Seroepidemiology of Viral Hepatitis in Hong Kong
ClinicalTrials.gov study NCT04371276. IPD Sharing: NO. Countries: 1. Publications: 1.
Evaluation of Role of Transient Elastography (Fibroscan) in Differentiating Patients of Acute Severe Viral Hepatitis and Acute on Chronic Liver Failure
ClinicalTrials.gov study NCT01866072. IPD Sharing: Not stated. Countries: 1. Publications: 8.
Molecular Characteristics and Prevalence of Viral Hepatitis E in Human Tissue and Cell Donors
ClinicalTrials.gov study NCT06457438. IPD Sharing: NO. Countries: 1. Publications: 6.
Durability of Virologic Response and/or Viral Resistance Patterns in Participants With Chronic Hepatitis C Who Have Been Previously Treated With Grazoprevir (MK-5172) (MK-5172-017)
ClinicalTrials.gov study NCT01667081. IPD Sharing: YES. Countries: 0. Publications: 1.
Hepatitis B Surface Antigen(HBsAg) Loss in Chronic Hepatitis B Patients With Low Viral Load
ClinicalTrials.gov study NCT00973219. IPD Sharing: Not stated. Countries: 1. Publications: 1.
An Anti-viral Combination Study With Japanese Hepatitis C Infection (HCV) Subject
ClinicalTrials.gov study NCT01051414. IPD Sharing: Not stated. Countries: 1. Publications: 3.
HCV (Hepatitis C Virus) Viral and Host Genotyping (IL28B, Interleukin 28B) in China
ClinicalTrials.gov study NCT01293279. IPD Sharing: Not stated. Countries: 1. Publications: 3.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.