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95 results for “viral suppression”
Type III interferons may suppress viral infections by triggering cell death -- Imaging Dataset
<p>This dataset accompanies the article "Type III interferons may suppress viral infections by triggering cell death". Earlier version is available as a preprint, <a href="https://doi.org/10.1101/2024.09.09.612051" target="_blank" rel="noopener">https://doi.org/10.1101/2024.09.09.612051</a>. The updated dataset includes quantifications for Figure 7C and Figure 7D.</p>
Long-Acting Cabotegravir Plus VRC-HIVMAB075-00-AB (VRC07-523LS) for Viral Suppression in Adults Living With HIV-1
ClinicalTrials.gov study NCT03739996. IPD Sharing: YES. Countries: 2. Publications: 1.
Epidemiologic data relating to age and gender specific HIV viral suppression in Rakai, Uganda, 2013-2019
<div> <p>This repository contains the data for the analyses presented in the paper "<span><span>Age and gender profiles of HIV infection burden and viraemia: novel metrics for HIV epidemic control in African populations with high antiretroviral therapy coverage</span></span>", soon available as a preprint. </p> <p>We thank all contributors, program staff, and participants to the Rakai Community Cohort Study.</p> <p>We also extend our gratitude to the <a href="https://doi.org/10.14469/hpc/2232">Imperial College Research Computing Service</a> for providing the computational resources to perform this study. Additionally, we thank the Office of Cyberinfrastructure and Computational Biology at the <a href="https://www.niaid.nih.gov/">National Institute for Allergy and Infectious Diseases</a> for data management support; and Zulip for sponsoring team communications through the Zulip Cloud Standard chat app. </p> <p>All analysis code is available from <a href="https://github.com/MLGlobalHealth/longi_viral_loads">https://github.com/MLGlobalHealth/longi_viral_loads</a>.</p> </div>
Trial to Assess the Impact of PrEP to Tenofovir Gel on the Efficacy of Tenofovir-containing ART on Viral Suppression
ClinicalTrials.gov study NCT01387022. IPD Sharing: Not stated. Countries: 1. Publications: 7.
Community Health Worker And MHealth to ImProve Viral Suppression
ClinicalTrials.gov study NCT04562649. IPD Sharing: NO. Countries: 1. Publications: 2.
Optimizing a Bio-behavioral Intervention for Sustained Viral Suppression
ClinicalTrials.gov study NCT05377463. IPD Sharing: YES. Countries: 1. Publications: 1.
Study To Evaluate Safety and Efficacy of Vesatolimod for the Treatment of Chronic Hepatitis B Virus in Virally-Suppressed Participants
ClinicalTrials.gov study NCT02166047. IPD Sharing: Not stated. Countries: 6. Publications: 2.
Safety and Efficacy of Celecoxib Plus Nucleos(t)Ide Analogues on the Hepatitis B Surface Antigen of Virally Suppressed Subjects With Chronic Hepatitis B
ClinicalTrials.gov study NCT05256823. IPD Sharing: NO. Countries: 1. Publications: 2.
Community Health Worker And MHealth to ImProve Viral Suppression (CHAMPS Pilot)
ClinicalTrials.gov study NCT05938413. IPD Sharing: NO. Countries: 1. Publications: 1.
Safety, Tolerability and Antiviral Activity of Selgantolimod in Virally-Suppressed Participants With Chronic Hepatitis B
ClinicalTrials.gov study NCT03491553. IPD Sharing: NO. Countries: 2. Publications: 1.
Evaluating HITSystem 2.1 to Improve Viral Suppression in Kenya
ClinicalTrials.gov study NCT04571684. IPD Sharing: YES. Countries: 1. Publications: 2.
Optimizing Viral Load Suppression in Kenyan Children on Antiretroviral Therapy
ClinicalTrials.gov study NCT03820323. IPD Sharing: YES. Countries: 1. Publications: 4.
Efficacy of Atazanavir/Ritonavir Monotherapy as Maintenance in Patients With Viral Suppression
ClinicalTrials.gov study NCT01511809. IPD Sharing: Not stated. Countries: 1. Publications: 10.
Evaluating the Safety and Efficacy of Romidepsin in Combination With Antiretroviral Therapy in HIV-Infected Adults With Suppressed Viral Load
ClinicalTrials.gov study NCT01933594. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Data from: Optimizing prevention of HIV mother to child transmission: duration of antiretroviral therapy and viral suppression at delivery among pregnant Malawian women
Background: Effective antiretroviral therapy during pregnancy minimizes the risk of vertical HIV transmission. Some women present late in their pregnancy for first antenatal visit; whether these women achieve viral suppression by delivery and how suppression varies with time on ART is unclear. Methods: We conducted a prospective cohort study of HIV-infected pregnant women initiating antiretroviral therapy for the first time from June 2015 to November 2016. Multivariable Poisson models with robust variance estimators were used to estimate risk ratios (RR) and 95% confidence intervals (CI) of the association between duration of ART and both viral load (VL) ≥1000 copies/ml and VL ≥40 copies/ml at delivery. Results: Of the 252 women who had viral load testing at delivery, 40 (16%) and 78 (31%) had VL ≥1000 copies/ml and VL ≥40 copies/ml, respectively. The proportion of women with poor adherence to ART was higher among women who were on ART for ≤12 weeks (9/50 = 18.0%) than among those who were on ART for 13-35 weeks (18/194 = 9.3%). Compared to women who were on ART for ≤12 weeks, women who were on ART for 13-20 weeks (RR = 0.52; 95% CI: 0.36-0.74) or 21-35 weeks (RR = 0.26; 95% CI: 0.14-0.48) had a lower risk of VL ≥40 copies/ml at delivery. Similar comparisons for VL ≥1000 copies/ml at delivery showed decrease in risk although not significant for those on ART 13-20 weeks. Conclusion: Longer duration of ART during pregnancy was associated with suppressed viral load at delivery. Early ANC attendance in pregnancy to facilitate prompt ART initiation for HIV-positive women is essential in the effort to eliminate HIV vertical transmission.
Reaching 90% HIV Suppression: The Role of POC Viral Load Monitoring in Nigeria
ClinicalTrials.gov study NCT03533868. IPD Sharing: YES. Countries: 1. Publications: 5.
Family-centered HIV Care, Viral Suppression and Retention in HIV-positive Children, Swaziland
ClinicalTrials.gov study NCT03397420. IPD Sharing: YES. Countries: 1. Publications: 1.
A Study to Evaluate the Safety and Effects of Repeated Doses of 3BNC117-LS and 10-1074-LS on Persistent Viral Reservoirs in People Living With HIV and on Suppressive Antiretroviral Therapy
ClinicalTrials.gov study NCT05612178. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Omuyambi: Traditional Healer Support to Improve HIV Viral Suppression in Rural Uganda
ClinicalTrials.gov study NCT05943548. IPD Sharing: YES. Countries: 1. Publications: 2.
Trial To Assess The Lipid-Lowering Effect Of Adding Tenofovir/Emtricitabine Co-Formulation Vs Placebo To Hiv-1-Infected Subjects With Dyslipidemia And Sustained Viral Load Suppression Under Monotherap
ClinicalTrials.gov study NCT01458977. IPD Sharing: Not stated. Countries: 1. Publications: 1.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.