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12 results for “vitamin B1”
Supplementary materials for: Use and detection of a vitamin B1 degradation product yields new views of the marine B1 cycle and plankton metabolite exchange
<p>Vitamin B1 (thiamin) is a vital nutrient for most cells in nature including marine plankton. Early and recent experiments show that B1 degradation products instead of B1 can support the growth of marine bacterioplankton and phytoplankton. However, the use and occurrence of some degradation products remain uninvestigated – namely N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine (FAMP) – which has been a focus of plant oxidative stress research. We investigated the relevance of FAMP in the ocean. Experiments and global ocean meta-omic data indicate that eukaryotic phytoplankton, including picoeukaryotes and harmful algal bloom species, use FAMP while bacterioplankton appear more likely to use deformylated FAMP, 4-amino-5-aminomethyl-2-methylpyrimidine (AmMP). Measurements of FAMP in seawater and biomass revealed that it occurs at picomolar concentrations in the surface ocean, heterotrophic bacterial cultures produce FAMP in the dark – indicating non-photodegradation of B1 by cells, and B1-requiring (auxotrophic) picoeukaryotic phytoplankton produce intracellular FAMP. Our results require an expansion of thinking about vitamin degradation in the sea, but also the marine B1 cycle – where it is now crucial to consider a new B1-related compound pool (FAMP) – as well as generation (dark degradation – likely via oxidation), turnover (plankton uptake), and exchange of the compound within networks of plankton.</p>
High Dose Vitamin B1 to Reduce Abusive Alcohol Use
ClinicalTrials.gov study NCT00680121. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Supplementary materials for: Use and detection of a vitamin B1 degradation product yields new views of the marine B1 cycle and plankton metabolite exchange
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Effects of Vitamin B1 in Type 1 Diabetic Patients
ClinicalTrials.gov study NCT00117026. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Data from: Simultaneous determination of underivatized vitamin B1 and B6 in whole blood by Reversed Phase Ultra High Performance Liquid Chromatography Tandem Mass spectrometry
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Effects of Glucocorticoid Combined With Vitamin C and Vitamin B1 on Microcirculation in Severe Septic Shock
ClinicalTrials.gov study NCT03821714. IPD Sharing: NO. Countries: 1. Publications: 0.
Vitamin C, Vitamin B1 and Steroid in Sepsis
ClinicalTrials.gov study NCT04039815. IPD Sharing: NO. Countries: 1. Publications: 0.
Efficacy of Vitamin B1 in Familial Adenomatous Polyposis Patients.
ClinicalTrials.gov study NCT06649825. IPD Sharing: YES. Countries: 1. Publications: 0.
Thiamin (Vitamin B1) Levels in Eating Disorder Adolescent Patients
ClinicalTrials.gov study NCT02164487. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The prominent transcriptional and metabolites changes of Mycobacterium bovis BCG str. Tokyo 172 induced by vitamin B1
GEO Series GSE114949. Mycobacterium tuberculosis variant bovis. 6 samples. Type: Expression profiling by high throughput sequencing.
Creatine, D-Ribose, B1 Vitamin, and B6 Vitamin in Ischemic Heart Disease
ClinicalTrials.gov study NCT03411369. IPD Sharing: NO. Countries: 0. Publications: 0.
The prominent transcriptional changes of Mycobacterium bovis BCG str. Tokyo 172 following induction by vitamin B1
GEO Series GSE101963. Mycobacterium tuberculosis variant bovis. 2 samples. Type: Expression profiling by high throughput sequencing.
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