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16
datasets available to search
ShareScore release 0.9.0
Dataset results
16 results for “white matter changes”
Cognitive Changes in Alzheimer's Disease Patients Associated With or Without White Matter Changes After Rivastigmine
ClinicalTrials.gov study NCT01380288. IPD Sharing: Not stated. Countries: 1. Publications: 1.
TORIE-DTI: Transient white matter changes under sevoflurane anesthesia
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Association of gyrification pattern, white matter changes and phenotypic profile in patients with Parkinson's disease
<p><b>Objective:</b> To investigate the cortical gyrification changes as well as their relationships with white matter (WM) microstructural abnormalities in the akinetic-rigid (AR) and tremor-dominant (TD) subtypes of Parkinson's disease (PD).</p> <p><b>Methods:</b> Sixty-four patients with the AR subtype, 26 patients with the TD subtype and 56 healthy controls (HCs) were included in this study. High-resolution T1-weighted and diffusion-weighted images were acquired for each participant. We computed local gyrification index (LGI) and fractional anisotropy (FA) to identify the cortical gyrification and WM microstructural changes in the AR and TD subtypes.</p> <p><b>Results: </b>Compared with HCs, patients with the AR subtype showed decreased LGI in the precentral, postcentral, inferior and superior parietal, middle and superior frontal/temporal, anterior and posterior cingulate, orbitofrontal, supramarginal, precuneus, and some visual cortices, and decreased FA in the corticospinal tract, inferior and superior longitudinal fasciculus, inferior fronto-occipital fasciculus, forceps minor/major, and anterior thalamic radiation. Decreases in LGI and FA of the AR subtype were found to be tightly coupled. LGIs of the left inferior and middle frontal gyrus correlated with the mini-mental state examination and the Hoehn and Yahr scores of patients with the AR subtype. Patients with the TD subtype showed no significant change in the LGI and FA compared with patients with the AR subtype and HCs.</p> <p><b>Conclusions:</b> Our results suggest that cortical gyrification changes in PD are motor phenotype-specific and are possibly mediated by the microstructural abnormalities of the underlying WM tracts.</p>
A Pilot Study to Evaluate Neurocognitive Injury and Longitudinal Changes in White Matter During Radiation Therapy in Children With Primary Brain Tumors
ClinicalTrials.gov study NCT02006407. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Association of gyrification pattern, white matter changes and phenotypic profile in patients with Parkinson’s disease
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DNA methylation changes in glial cells implicate functional changes in oligodendrocytes, astrocytes and microglial cells in the normal appearing white matter of Multiple Sclerosis patients
GEO Series GSE166207. Homo sapiens. 44 samples. Type: Methylation profiling by genome tiling array.
Transcriptional profiling identifies white matter changes in eNOS+/- mice II
GEO Series GSE207960. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Structural and Functional Grey and White Matter Changes in Patients With Pain Disorders
ClinicalTrials.gov study NCT05679297. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Effectiveness of Tai Chi and Acupuncture on Migraine Attack Prevention and Brain White Matter Changes: A Non-Inferiority RCT
ClinicalTrials.gov study NCT06967909. IPD Sharing: NO. Countries: 1. Publications: 0.
Brain Function and White Matter Changes in Congenital, Acute and Chronic Spinal Cord Lesions
ClinicalTrials.gov study NCT01208584. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Decoding Presymptomatic White Matter Changes in Huntington Disease
ClinicalTrials.gov study NCT03193099. IPD Sharing: NO. Countries: 1. Publications: 0.
Pre-Clinical White Matter Changes and Associated Connectivity Effects in Fabry Disease
ClinicalTrials.gov study NCT03678324. IPD Sharing: NO. Countries: 1. Publications: 0.
Transcriptional profiling of human microglia reveals grey-white matter heterogeneity and multiple sclerosis-associated changes
GEO Series GSE111972. Homo sapiens. 31 samples. Type: Expression profiling by high throughput sequencing.
Application of Diffusion Tensor Imaging in Alzheimer's Disease :Quantification of White Matter Micro-structural Changes
ClinicalTrials.gov study NCT03255720. IPD Sharing: NO. Countries: 0. Publications: 0.
Transcriptional profiling identifies white matter changes in eNOS+/- mice I
GEO Series GSE207961. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Transcriptional profiling identifies white matter changes in eNOS+/- mice
GEO Series GSE207962. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.