Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
18
datasets available to search
ShareScore release 0.9.0
Dataset results
18 results for “xanthones”
Elucidating the Polymorphism of Xanthone: A Crystallization and Characterization Study
<p>Dataset related to the publication: "Elucidating the Polymorphism of Xanthone: A Crystallization and Characterization Study". Accepted in Crystal Growth and Design on February 9th, 2024.</p> <p>Abstract: The aim of this work is to shed light on the polymorphism of xanthones, a class of oxygenated molecules well known for their bioactivity, including antioxidant, anticancer, and anti-inflammatory effects. Understanding the polymorphism of xanthones can enable the design of novel solid products for pharmaceutical, nutraceutical, and agrochemical applications. Prior to this work, two entries accounting for different space groups were deposited for 9-xanthone in the Cambridge Structure Database (CSD): an orthorhombic P212121 and a monoclinic P21 structure solved at room and low temperatures, respectively. However, the very high similarity between these two structures and the lack of clear differences in the physical properties (e.g., thermal behavior) suggested the possibility of the existence of only one crystal structure. In fact, the differences shown in the literature data might be related to the chosen operating parameters, as well as the instrumental resolution of the single-crystal X-ray diffraction experiments. In the work presented here, the ambiguity in the polymorphism of xanthone is investigated using thermal analysis, powder and synchrotron single-crystal XRD, and optical microscopy. Additionally, a workflow for the correct identification of twinned crystal structures, which can be applied to other polymorphic systems, is presented. Such workflow combines the collection of a large data set of high-resolution diffraction patterns using synchrotron radiation with the use of principal component analysis, a dimensionality reduction technique, for a quick and effective identification of phase transitions happening during the data collection. Crystallization experiments were designed to promote the formation of different crystal structures of xanthone that were recrystallized based on past literature and beyond.</p>
Hydrogen-bonded xanthones as potential UV absorbers. The synthesis of xanthones from bio-renewable cardanol utilizing a ceric ammonium sulfate (CAS) mediated oxidation reaction
<p>The synthesis of hydrogen-bonded xanthones using the bio-renewable phenol, cardanol is described. Cardanol was initially converted into hydroxy-benzophenones. These benzophenones were converted into xanthones utilizing an oxidative ceric ammonium sulfate (CAS) mediated reaction. Subsequent ruthenium-mediated late-stage oxidation of the xanthones provided hydrogen-bonded xanthones, which displayed good UVA and UVB absorbing properties.</p>
Development of xanthone derivatives as effective broad-spectrum antimicrobials: Disrupting cell wall and inhibiting DNA synthesis
Open the record for dataset details and reuse information.
Fig. 3 in Prenylated cyclohexene-type meroterpenoids and sulfur-containing xanthones produced by Pseudopestalotiopsis theae
Fig. 3. Mosher model for (methoxyphenyl)acetic acid MPA ester and Δδ (δR – δS) values (in ppm) derived from the chemical shifts of the (R)-MPA and (S)-MPA esters of 1A.
Fig. 6 in Prenylated cyclohexene-type meroterpenoids and sulfur-containing xanthones produced by Pseudopestalotiopsis theae
Fig. 6. Experimental ECD spectrum of 3 measured in MeCN compared with the Boltzmann-weighted PBE0/TZVP PCM/MeCN ECD spectrum of (1R,2R,3S,4S)-3 computed for the ωB97X/TZVP PCM/MeCN conformers. Bars represent the rotational strength values of the lowest-energy conformer.
Fig. 2. Observed 1H–1H in Cytotoxic xanthone derivatives from the twigs of Garcinia oligantha
Fig. 2. Observed 1H–1H COSY (blue lines) and Key HMBC (red arrows) correlations of 1–10. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)
Bioavailability of Xanthones From Mangosteen
ClinicalTrials.gov study NCT01425047. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Fig. 7. 1H–1H in Prenylated cyclohexene-type meroterpenoids and sulfur-containing xanthones produced by Pseudopestalotiopsis theae
Fig. 7. 1H–1H COSY (bold) and selected HMBC (plain) correlations of 3–5.
Fig. 5. Keys NOE correlations for compounds 3, 4, 5 in Prenylated cyclohexene-type meroterpenoids and sulfur-containing xanthones produced by Pseudopestalotiopsis theae
Fig. 5. Keys NOE correlations for compounds 3, 4, 5.
Fig. 4. Plausible biosynthetic pathway for sydoxanthones D and E in Prenylated cyclohexene-type meroterpenoids and sulfur-containing xanthones produced by Pseudopestalotiopsis theae
Fig. 4. Plausible biosynthetic pathway for sydoxanthones D and E.
Fig. 2. 1H-1H in Prenylated cyclohexene-type meroterpenoids and sulfur-containing xanthones produced by Pseudopestalotiopsis theae
Fig. 2. 1H-1H COSY (bold) and HMBC (plain) correlations of1.
Fig. 1 in Prenylated cyclohexene-type meroterpenoids and sulfur-containing xanthones produced by Pseudopestalotiopsis theae
Fig. 1. Structures of compounds 1–10.
Fig. 1 in Cytotoxic xanthone derivatives from the twigs of Garcinia oligantha
Fig. 1. Structures of compounds 1–10..
Fig. 3 in Cytotoxic xanthone derivatives from the twigs of Garcinia oligantha
Fig. 3. ORTEP diagram of compound 1.
Fig. 6 in Cytotoxic xanthone derivatives from the twigs of Garcinia oligantha
Fig. 6. Plausible biosynthesis pathways of 1.
Lion from Xanthon
Reliefed lion atacking a deer, British Museum, London Model made by Oskar Kubrak for research project "The Lions Greek Sculpture: From the Beginning to the Beauty Art". Source: Objaverse 1.0 / Sketchfab
Mangoselect®: Characterization, Pharmacokinetics and Bioavailability of Xanthone Metabolites
ClinicalTrials.gov study NCT04151641. IPD Sharing: NO. Countries: 1. Publications: 0.
Fig. 4 in Cytotoxic xanthone derivatives from the twigs of Garcinia oligantha
Fig. 4. Calculated and experimental ECD spectra of 1, 2, 3, and 8.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.