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NIH funding notice PA-18-141

Mechanisms, Models, Measurement, and Management in Pain Research (R01 Clinical Trial Optional)

Closed on May 7, 2021.

Posted
November 7, 2017
Close date
May 7, 2021
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov ยท NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

85 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $43,650,607 in first-year total cost, median $505,161.

Most frequent study sections

  1. Somatosensory and Pain Systems Study Section[SPS]22
  2. Behavioral Medicine, Interventions and Outcomes Study Section[BMIO]9
  3. Neurobiology of Pain and Itch Study Section [NPI]5
  4. Clinical Management of Patients in Community-based Settings Study Section[CMPC]4
  5. Molecular Neuropharmacology and Signaling Study Section[MNPS]4

Most frequent institutions

  1. JOHNS HOPKINS UNIVERSITY5
  2. UNIVERSITY OF MARYLAND BALTIMORE5
  3. CINCINNATI CHILDRENS HOSP MED CTR4
  4. UNIVERSITY OF IOWA4
  5. UNIVERSITY OF PITTSBURGH AT PITTSBURGH4
Competing awards under PA-18-141 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2022Genetic and Environmental Origins of the Development of Pain in Children2R01HD086085-06DAVIS, MARY COLLEENLEMERY-CHALFANT, KATHRYNARIZONA STATE UNIVERSITY-TEMPE CAMPUS, AZ$633,050MESH
2022Delivery of an At-Home Nonpharmacologic Intervention (Transcranial Neurostimulation) to Mitigate Pain in Patients with End Stage Kidney Disease Receiving Hemodialysis1R01DK131050-01KNOTKOVA, HELENAREID, MANNEY CARRINGTONWEILL MEDICAL COLL OF CORNELL UNIV, NY$630,815CMGC
2022Amygdala kappa opioid system involvement in opioid relapse in pain states1R01DA053752-01A1CAHILL, CATHERINE MUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$570,428MNPS
2022Neuropeptidergic Inhibition of Spinal Pain Transmission2R01NS045954-17TAYLOR, BRADLEY K.UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$505,161NPI
2022Molecular basis for adenosine A3 receptor agonists in the treatment of migraine1R01NS120930-01A1AKERMAN, SIMONSALVEMINI, DANIELAUNIVERSITY OF MARYLAND BALTIMORE, MD$498,920MNPS
2022Cell-directed gene therapy for pain recovery after surgery and inflammation1R01NS122153-01A1MARTIN, THOMAS JEFFREYROMERO-SANDOVAL, E. ALFONSOWAKE FOREST UNIVERSITY HEALTH SCIENCES, NC$465,287NPI
2022Forecasting Migraine Attacks1R01NS121233-01A1HOULE, TIMOTHY TMASSACHUSETTS GENERAL HOSPITAL, MA$422,817BMHO
2022Promoting Effective Self-Management of Chronic Pain with mHealth Neurofeedback1R01NR019788-01A1ELBOGEN, ERIC B.DUKE UNIVERSITY, NC$402,500BMHO
2022Short-chain fatty acids and chronic temporomandibular joint pain1R01DE031255-01TAO, FENGTEXAS A&M UNIVERSITY HEALTH SCIENCE CTR, TX$359,813ODCS
2021Yoga for Chemotherapy-induced Peripheral Neuropathy Treatment (YCT) Trial1R01CA251470-01A1BAO, TINGSLOAN-KETTERING INST CAN RESEARCH, NY$729,813CMPC
2021Acupuncture for Chemothrapy-induced Peripheral Neuropathy Treatment (ACT)Trial1R37CA248563-01A1BAO, TINGSLOAN-KETTERING INST CAN RESEARCH, NY$676,665CMPC
2021Development of Hsp90 Isoform- Selective Inhibitors as a Novel Opioid Dose-Reduction Therapy1R01DA052340-01A1STREICHER, JOHN MICHAELUNIVERSITY OF ARIZONA, AZ$657,854DDNS
2021An Efficacy Trial of Community Health Worker-Delivered Chronic Pain Self-Management Support for Vulnerable Older Adults1R01AG071511-01JANEVIC, MARY ROSEUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$617,996BMIO
2021Study of Activity-Dependent Sympathetic Sprouting2R01NS045594-16ZHANG, JUN-MINGUNIVERSITY OF CINCINNATI, OH$550,755NPI
2021Mechanisms of Pain Associated with Trigeminal Nerve Injury1R01NS122784-01GOLD, MICHAEL SSEKULA, RAYMOND FUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$548,954NPI
2021Sensory Function and Chronic Pain in Cerebral Palsy1R01HD102552-01A1SYMONS, FRANK JUNIVERSITY OF MINNESOTA, MN$524,361BMIO
2021Identification of a novel DRG-specific long noncoding RNA and its role in neuropathic pain1R01NS117484-01A1HU, HUIJUANTAO, YUAN-XIANGRBHS-NEW JERSEY MEDICAL SCHOOL, NJ$490,258ZRG1
2021Promoting Self-Management of Breast and Nipple Pain with Technology (PROMPT) for Breastfeeding Women1R56NR020041-01LUCAS, RUTH FUNIVERSITY OF CONNECTICUT STORRS, CT$484,689CMGC
2021A prolactin-mediated neuroendocrine link between stress-induced latent sensitization and female-selective pain1R01NS120395-01A1NAVRATILOVA, EDITANEUGEBAUER, VOLKERPORRECA, FRANKUNIVERSITY OF ARIZONA, AZ$470,170BNRS
2021Neural Mechanisms Underlying IC/BPS1R01DK128475-01SAMINENI, VIJAY KWASHINGTON UNIVERSITY, MO$469,356ZRG1
2021Cortical-meningeal interactions underlying migraine headache1R01NS115972-01A1LEVY, DANBETH ISRAEL DEACONESS MEDICAL CENTER, MA$446,297SPS
2021Sympathetic modulation of head and neck cancer pain1R01DE030892-01SCHEFF, NICOLE NUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$371,688NPI
2021Anti-CV2 autoantibodies unmask a CRMP5/GluN2B pain signaling hub1R01NS119263-01MOUTAL, AUBINUNIVERSITY OF ARIZONA, AZ$368,934SPS
2021Evaluation of TRPM8-expressing neurons as novel regulators of acute radiotherapy-associated pain in patients with head and neck cancer1R37CA248797-01A1NOLAN, MICHAEL WARRENNORTH CAROLINA STATE UNIVERSITY RALEIGH, NC$360,659RTB
2021Pilot Testing A Theory-Driven Self- Management Intervention for Chronic Musculoskeletal Pain1R56NR019813-01KAWI, JENNIFERYEH, CHAO HSINGJOHNS HOPKINS UNIVERSITY, MD$13,767BMIO
2020CNS Pain Mechanisms in Early Rheumatoid Arthritis: Implications for the Acute to Chronic Pain Transition2R01AR064850-07A1LEE, YVONNE CLAIRENORTHWESTERN UNIVERSITY AT CHICAGO, IL$893,626NAME
2020Androgen Replacement to Improve Patient-Important Outcomes in Men with Opioid-Induced Hypogonadism1R01AG066921-01A1BASARIA, SHEHZADEDWARDS, ROBERT RBRIGHAM AND WOMEN'S HOSPITAL, MA$752,769SPS
2020Individualized Assessment and Treatment Program for TMD: Coping as a Mechanism1U01DE028520-01A1LITT, MARK D.UNIVERSITY OF CONNECTICUT SCH OF MED/DNT, CT$748,865BMIO
2020Pain in community-based older African American Adults: The Jackson Heart Study1R01AG066914-01A1BENJAMIN, EMELIA J.EDWARDS, ROBERT RNEOGI, TUHINASIMS, MARIOBOSTON UNIVERSITY MEDICAL CAMPUS, MA$702,564NAME
2020Evaluation of small-fiber polyneuropathy in youth2R01NS093653-06OAKLANDER, ANNE LOUISEMASSACHUSETTS GENERAL HOSPITAL, MA$684,116SPS
2020Birth Tissue Products for Non-opioid Treatment of Post-surgical Pain1R01NS117761-01GUAN, YUNJOHNS HOPKINS UNIVERSITY, MD$660,845SPS
2020Auricular Point Acupressure to Manage Chemotherapy Induced Neuropathy1R01CA245054-01A1YEH, CHAO HSINGJOHNS HOPKINS UNIVERSITY, MD$656,091CMPC
2020A Mobile Health Behavioral Pain Intervention Protocol for Breast Cancer Patients with Pain in Medically Underserved Communities: A Randomized Controlled Trial1R01CA237892-01A1SOMERS, TAMARA JDUKE UNIVERSITY, NC$633,405BMIO
2020Disruption of Homeostatic Neuroimmune Interactions in Descending Circuitry in the Development of Pain Chronicity1R01DE029946-01REN, KEWEI, FENGUNIVERSITY OF MARYLAND BALTIMORE, MD$620,698SPS
2020Lumbar Stenosis Prognostic Subgroups for Personalizing Care and Treatment (PROSPECTS)1R01AG069891-01RUNDELL, SEAN DANIELUNIVERSITY OF WASHINGTON, WA$611,088NAME
2020Biobehavioral basis of knee osteoarthritis pain1R01AG067757-01CRUZ-ALMEIDA, YENISELUNIVERSITY OF FLORIDA, FL$566,184ZRG1
2020Diverging Effects of Closeness in Older Adults with Chronic Low Back Pain and Spousal Caregivers1R01AG063241-01A1MARTIRE, LYNN M.PENNSYLVANIA STATE UNIVERSITY, THE, PA$533,362SPIP
2020Schwann cell activation in oral cancer perineurial invasion and neuropathic pain1R01DE029493-01YE, YINEW YORK UNIVERSITY, NY$522,070SPS
2020Mechanisms of muscle afferent sensitization after ischemia1R01NS113965-01A1JANKOWSKI, MICHAEL PCINCINNATI CHILDRENS HOSP MED CTR, OH$495,333SPS
2020Lymphotoxin-beta receptor peripheral signaling regulates the transition to inflammation and neuropathy-induced chronic pain1R01NS112263-01A1AKOPIAN, ARMEN NTUMANOV, ALEXEI VUNIVERSITY OF TEXAS HLTH SCIENCE CENTER, TX$489,115SPS
2020Efficient and Cost-Effective Multimodal System for Pain Management in Low Back Pain1R01NR018451-01A1HAMMAL, ZAKIACARNEGIE-MELLON UNIVERSITY, PA$486,755BCHI
2020Cross-talk between the colon epithelium, colon afferents and sympathetic neurons regulate pain in the normal and inflamed colon1R01DK124955-01ALBERS, KATHRYN MARIEDAVIS, BRIAN MGOLD, MICHAEL SUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$453,099ZRG1
2020A Female Specific Role of RGSz1 in Modulation of Chronic Pain1R01NS111351-01A1ZACHARIOU, VENETIAICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$432,567MIST
2020Endoplasmic Reticulum Stress Responses in Pain1R01NS114653-01BOADA, MARIO DANILOROMERO-SANDOVAL, E. ALFONSOWAKE FOREST UNIVERSITY HEALTH SCIENCES, NC$412,151SPS
2020Stress-induced plasticity in noradrenergic analgesia1R01NS117899-01MCCALL, JORDAN G.WASHINGTON UNIVERSITY, MO$405,396SPS
2020Profiling Translation in Nociceptor Plasticity1R01NS114018-01A1CAMPBELL, ZACHARYUNIVERSITY OF TEXAS DALLAS, TX$403,530SPS
2020Sleep fragmentation by brief awakenings as a surrogate to measure neuropathic spontaneous pain1R01NS112266-01A1LATREMOLIERE, ALBAN AJOHNS HOPKINS UNIVERSITY, MD$384,813NNRS
2020Development of a deep neural network to measure spontaneous pain from mouse facial expressions1R01NS114259-01ZYLKA, MARK J.UNIV OF NORTH CAROLINA CHAPEL HILL, NC$364,998SPS
2020The Role of the Voltage-Gated Sodium Channel, NaV1.8, in Silent Inflammatory Bowel Disease1R01DK122364-01A1COATES, MATTHEW DPENNSYLVANIA STATE UNIV HERSHEY MED CTR, PA$348,671ZRG1
2020The Demography of Chronic Pain: A Population Approach to Pain Trends, Pain Disparities, and Pain-Related Disability and Death1R01AG065351-01A1GROL-PROKOPCZYK, HANNASTATE UNIVERSITY OF NEW YORK AT BUFFALO, NY$317,323SSPA
2020Metabolic Biomarkers for Fibromyalgia1R01AR077418-01FREY LAW, LAURA ASCHREPF, ANDREWSLUKA, KATHLEEN AUNIVERSITY OF IOWA, IA$284,554ZRG1
2019Dissecting Neural Mechanisms Supporting Mind and Body Approaches to Pain Reduction in Youth with Migraine1R01AT010171-01COGHILL, ROBERT CPOWERS, SCOTT WCINCINNATI CHILDRENS HOSP MED CTR, OH$781,682ZRG1
2019Explosive Synchronization of Brain Network Activity in Chronic Pain1R01AT010060-01A1DASILVA, ALEXANDREHARRIS, RICHARD ELEE, UNCHEOLUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$750,222SPS
2019Brain Pathophysiology of Osteoarthritis Pain1R01AR074274-01A1APKARIAN, APKAR VANIANORTHWESTERN UNIVERSITY AT CHICAGO, IL$691,181BMIO
2019Dysfunction of Sodium Homeostasis in Migraine2R01NS072497-06A1GRANT, SAMUEL COLLESHARRINGTON, MICHAEL GORDONPETZOLD, LINDA R.HUNTINGTON MEDICAL RESEARCH INSTITUTES, CA$675,437ANIE
2019Preventing Persistent Post-Surgical Pain and Dysfunction in At-Risk Veterans: Effect of a Brief Behavioral Intervention1R01NR017610-01A1DINDO, LILIAN NAZARRAKEL, BARBARAUNIVERSITY OF IOWA, IA$673,800ZNR1
2019Advancing Knowledge Discovery for Postoperative Pain Management1R01LM013362-01A1HERNANDEZ-BOUSSARD, TINASTANFORD UNIVERSITY, CA$668,723BCHI
2019Pathways from Chronic Prescription Opioid Use to New Onset Mood Disorder1R01DA043811-01A1SCHERRER, JEFFREY F.SAINT LOUIS UNIVERSITY, MO$650,897BGES
2019Neurophysiological and transcriptomic predictors of chronic low back pain: towards precision pain management (NEAT Study)1R01NR018595-01DORSEY, SUSAN GRENN, CYNTHIA LSTARKWEATHER, ANGELA RENEEUNIVERSITY OF MARYLAND BALTIMORE, MD$638,021NRCS
2019Epigenetic Determinants Influencing Development and Evolution of Chronic Post-surgical Pain in Children Undergoing Musculoskeletal Surgery.1R01AR075857-01CHIDAMBARAN, VIDYACINCINNATI CHILDRENS HOSP MED CTR, OH$629,701MESH
2019The Role of Opioid Adherence Profiles in Cancer Pain Self-Management and Outcomes1R01NR017853-01A1MEGHANI, SALIMAH H.UNIVERSITY OF PENNSYLVANIA, PA$564,960CMPC
2019An AHEI Dietary Intervention to Reduce Pain in Women with Endometriosis1R01NR017951-01A1HARRIS, HOLLY RUTHFRED HUTCHINSON CANCER RESEARCH CENTER, WA$555,948ZRG1
2019Impact of Prescription Opioid Dose Changes on Cannabis Use and Clinical Outcomes1R01DA048817-01MORASCO, BENJAMIN J.OREGON HEALTH & SCIENCE UNIVERSITY, OR$537,390ARM
2019Role of macrophages in activity-induced pain and analgesia1R01AR073187-01A1SLUKA, KATHLEEN AUNIVERSITY OF IOWA, IA$529,511ZRG1
2019Defining the role of peripheral Adrb3 in chronic pain and inflammation1R01NS109541-01A1NACKLEY, ANDREA GDUKE UNIVERSITY, NC$525,095ZRG1
2019Effects of Tai Chi on Multisite Pain and Falls in Older Adults1R56AG062737-01A1LEVEILLE, SUZANNE G.YOU, TONGJIANUNIVERSITY OF MASSACHUSETTS BOSTON, MA$523,133BMIO
2019A Female Specific Role of RGSz1 in Modulation of Chronic Pain1R56NS111351-01ZACHARIOU, VENETIAICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$516,975MIST
2019Role of dorsal root ganglion FTO, a RNA demethylase, in neuropathic pain1R01NS111553-01A1TAO, YUAN-XIANGRBHS-NEW JERSEY MEDICAL SCHOOL, NJ$509,884ZRG1
2019Mechanistic Study of Pain Inhibition by Activation of Non-nociceptive Afferent Fibers1R01NS110598-01GUAN, YUNJOHNS HOPKINS UNIVERSITY, MD$499,847SPS
2019Perivascular mechanisms of CGRP-induced migraine symptoms2R01NS075599-06RUSSO, ANDREW FUNIVERSITY OF IOWA, IA$482,652SPS
2019Adenylyl cyclase signaling in persistent pain1R01NS109936-01A1MOLLIVER, DEREK CUNIVERSITY OF NEW ENGLAND, ME$463,248SPS
2019Neuropathic Pain-induced Depression: the Role of mPFC Endocannabinoids1R01NS112194-01PAN, BINMEDICAL COLLEGE OF WISCONSIN, WI$426,771MNPS
2019Mechanisms in primary nociceptors that drive ongoing activity and ongoing pain1R01NS111521-01WALTERS, EDGAR T.ZHU, MICHAEL XUNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX$417,626SPS
2019Enteric glia and visceral pain1R01DK120862-01GULBRANSEN, BRIAN D.MICHIGAN STATE UNIVERSITY, MI$417,490ZRG1
2019Cerebral oscillations of pain1R01NS112356-01SEMINOWICZ, DAVIDUNIVERSITY OF MARYLAND BALTIMORE, MD$414,653BMIO
2019Sensitization of developing sensory neurons after incision1R01NS105715-01A1JANKOWSKI, MICHAEL PCINCINNATI CHILDRENS HOSP MED CTR, OH$410,648SPS
2019Cellular mechanisms of antidepressant drug actions in neuropathic pain models2R01NS086444-06ZACHARIOU, VENETIAICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$387,462MNPS
201915-LOX-1 as a druggable target in the acute to chronic pain transition of rheumatoid arthritis1R01AR075241-01A1GREGUS, ANN MARIEVIRGINIA POLYTECHNIC INST AND ST UNIV, VA$353,100SPS
2019Mechanisms of chronic pain maintained by ongoing nociceptor inputs in females1R01NS112344-01LA, JUN-HOUNIVERSITY OF TEXAS MED BR GALVESTON, TX$345,625SPS
2019Mechanisms for Omega-6 Modulation of Primary Afferent Nociceptors1R01NS110948-01A1HARGREAVES, KENNETH MUNIVERSITY OF TEXAS HLTH SCIENCE CENTER, TX$336,875SPS
2019Measuring Migraine Attack Risks1R01NS113823-01TURNER, DANAMASSACHUSETTS GENERAL HOSPITAL, MA$293,125BMIO
2018Characterization of central pain mechanisms using simultaneous spinal cord-brain functional imaging1R01NS109450-01GLOVER, GARY HMACKEY, SEAN CSTANFORD UNIVERSITY, CA$595,757ZRG1
2018Real-time imaging of skeletal muscle innervating sensory neurons that signal pain and fatigue1R01NS109140-01LIGHT, ALAN RWOODBURY, CHARLES JEFFERYUNIVERSITY OF UTAH, UT$510,410ZRG1
2018Fn14, non-canonical NF-kappaB and downstream signaling in neuropathic pain1R01NS105633-01A1SIMARD, J. MARCUNIVERSITY OF MARYLAND BALTIMORE, MD$373,122CMBG
2018MECHANISMS OF CSD-EVOKED PERSISTENT ACTIVATION OF MENINGEAL NOCICEPTORS2R01NS078263-05A1LEVY, DANBETH ISRAEL DEACONESS MEDICAL CENTER, MA$364,641ZRG1

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