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NIH funding notice PAR-12-109

Targeting Persistent HIV Reservoirs (TaPHIR) (R21/R33)

Closed on April 25, 2014.

Posted
February 17, 2012
Close date
April 25, 2014
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

32 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $7,462,841 in first-year total cost, median $231,446.

Most frequent study sections

  1. Special Emphasis Panel[ZRG1 AARR-K (51)]24
  2. Special Emphasis Panel[ZAI1 JRR-A (S4)]8

Most frequent institutions

  1. TULANE UNIVERSITY OF LOUISIANA3
  2. CASE WESTERN RESERVE UNIVERSITY2
  3. FRED HUTCHINSON CANCER RESEARCH CENTER2
  4. MASSACHUSETTS GENERAL HOSPITAL2
  5. UNIVERSITY OF MICHIGAN AT ANN ARBOR2
Competing awards under PAR-12-109 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2014Curing HIV Through Allogeneic Hematopoietic Stem Cell Transplantation1R21AI116184-01KEAN, LESLIE SSEATTLE CHILDREN'S HOSPITAL, WA$323,513ZRG1
2014Specific activation of latent HIV-1 by inhibiting E3 ubiquitin ligase activity1R21AI110166-01DOUGHERTY, JOSEPHRBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL, NJ$315,279ZAI1
2014Characterization of follicular dendritic cells as a reservoir for HIV1R21AI110164-01A1CARROLL, MICHAEL CRAIGBOSTON CHILDREN'S HOSPITAL, MA$263,875ZRG1
2014Cell-Based Secretion of Antiviral Molecules as a Treatment for HIV-AIDS1R21AI110154-01KIEM, HANS-PETERFRED HUTCHINSON CANCER RESEARCH CENTER, WA$259,621ZAI1
2014Alpha Emitter Labeled Anti-T Cell Antibody: Targeting Latent HIV Infected Cells1R21AI116225-01SANDMAIER, BRENDA MARIEFRED HUTCHINSON CANCER RESEARCH CENTER, WA$256,599ZRG1
2014Targeting SIV reservoirs with type I Interferons1R21AI116200-01SILVESTRI, GUIDOEMORY UNIVERSITY, GA$255,794ZRG1
2014Suppressing the latent reservoir with a Tat inhibitor1R21AI116226-01VALENTE, SUSANA TSCRIPPS FLORIDA, FL$255,150ZRG1
2014Adipose Tissue is a significant reservoir for HIV1R21AI116208-01BALASUBRAMANYAM, ASHOKLEWIS, DOROTHY E.UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX$252,313ZRG1
2014Effective lethal agents for CCR5???expressing cells1R21AI116230-01HARTIGAN-O'CONNOR, DENNIS J.UNIVERSITY OF CALIFORNIA AT DAVIS, CA$251,938ZRG1
2014Evaluating HIV expression and latency in blood and tissues at the single cell level1R21AI116218-01WONG, JOSEPH KNORTHERN CALIFORNIA INSTITUTE/RES/EDU, CA$246,906ZRG1
2014Therapeutic vaccination targeting SIV viral reservoirs1R21AI116211-01VEZYS, VAIVA DUNIVERSITY OF MINNESOTA, MN$240,193ZRG1
2014Targeting HIV-1 persistence with Interferon-a1R21AI116228-01YU, XUMASSACHUSETTS GENERAL HOSPITAL, MA$239,250ZRG1
2014Role of P-TEFB in HIV latency1R21AI116173-01RICE, ANDREW PBAYLOR COLLEGE OF MEDICINE, TX$236,491ZRG1
2014Inhibiting Immune Evasion by HIV-1 Nef to Facilitate Eradication1R21AI110162-01GUATELLI, JOHN C.VETERANS MEDICAL RESEARCH FDN/SAN DIEGO, CA$236,345ZAI1
2014Killing the Reservoir with Antibodies1R21AI110165-01ALTER, GALITMASSACHUSETTS GENERAL HOSPITAL, MA$235,561ZAI1
2014Targeting Cytolytic Cells to Lymphoid Sites of HIV Persistence.1R21AI116171-01LEDERMAN, MICHAEL MARCELPAIARDINI, MIRKOCASE WESTERN RESERVE UNIVERSITY, OH$234,742ZRG1
2014Targeting Macrophage Reservoirs in the Macaque Model of Pediatric AIDS1R21AI116198-01KURODA, MARCELO JTULANE UNIVERSITY OF LOUISIANA, LA$228,150ZRG1
2014Targeting latent HIV-1 Reservoirs with the Antibody-Drug Conjugate, Brentuximab Vedotin1R21AI116205-01HENRICH, TIMOTHY JENSENBRIGHAM AND WOMEN'S HOSPITAL, MA$224,439ZRG1
2014Targeting HIV Lung Reservoir in the Macaque Model1R21AI110163-01KURODA, MARCELO JTULANE UNIVERSITY OF LOUISIANA, LA$222,698ZAI1
2014Novel flow cytometry-based assay for HIV-infected cells1R21AI110143-01MCCUNE, JOSEPH MUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$220,601ZAI1
2014Kinomic analysis of host cell factors controlling latent HIV-1 infection1R21AI116188-01KUTSCH, OLAFUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$220,500ZRG1
2014An ex vivo model to predict outcomes and probe mechanism of anti-reservoir agents1R21AI116216-01O'DOHERTY, UNA TUNIVERSITY OF PENNSYLVANIA, PA$220,000ZRG1
2014Novell small molecules to reactivate latent HIV and sensitize to anti-viral therapies1R21AI116222-01D'ORSO, IVANMARTINEZ, ELISABETH DUT SOUTHWESTERN MEDICAL CENTER, TX$218,625ZRG1
2014HIV eradication by ADCC-activated NK cell killing1R21AI110156-01KARN, JONATHANCASE WESTERN RESERVE UNIVERSITY, OH$217,938ZAI1
2014Lineage marking in humanized mice to reveal HIV-1 reservoirs1R21AI116191-01CHEN, BENJAMIN KICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$210,841ZRG1
2014HIV-specific nucleases to reservoir cells1R21AI110149-01CANNON, PAULA MUNIVERSITY OF SOUTHERN CALIFORNIA, CA$205,208ZAI1
2014Purging the latent HIV reservoir at ART initiation: A new eradication strategy1R21AI116233-01CHOMONT, NICOLASTRAUTMANN, LYDIEVGTI FLORIDA, FL$201,497ZRG1
2014A family of compounds that reactivate latent HIV without T cell activation1R21AI116212-01BOSQUE, ALBERTOUNIVERSITY OF UTAH, UT$198,800ZRG1
2014Modified CMV-specific T cells to Target HIV1R21AI110158-01A1BRAUN, STEPHEN EDWARDTULANE UNIVERSITY OF LOUISIANA, LA$198,521ZRG1
2014High throughput analysis of latency/reactivation with barcoded proviruses1R21AI116190-01CHANG, CHEONG-HEEKIDD, JEFFREY MTELESNITSKY, ALICEUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$194,271ZRG1
2014Cooperation of BRD4 and TAT Associated Proteins in HIV Transcription and Latency1R21AI116180-01ZHU, JIANUNIVERSITY OF ROCHESTER, NY$190,270ZRG1
2014Development of Nef antagonists to enhance CTL clearance of HIV reservoirs1R21AI116158-01COLLINS, KATHLEEN L.UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$186,912ZRG1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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