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NIH funding notice PAR-13-146

NCI Exploratory/Developmental Research Grant Program (NCI Omnibus R21)

Closed on September 1, 2015.

Posted
March 19, 2013
Close date
September 1, 2015
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

517 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $100,959,328 in first-year total cost, median $199,610.

Most frequent study sections

  1. Special Emphasis Panel[ZCA1 RTRB-F (O1)]21
  2. Special Emphasis Panel[ZCA1 SRB-2 (O1)]19
  3. Special Emphasis Panel[ZCA1 RPRB-J (J1)]17
  4. Special Emphasis Panel[ZCA1 SRB-2 (J1)]16
  5. Special Emphasis Panel[ZCA1 RPRB-0 (O1)]15

Most frequent institutions

  1. UNIVERSITY OF TX MD ANDERSON CAN CTR14
  2. DUKE UNIVERSITY12
  3. SLOAN-KETTERING INST CAN RESEARCH12
  4. UNIVERSITY OF CALIFORNIA, SAN FRANCISCO12
  5. YALE UNIVERSITY12
Competing awards under PAR-13-146 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2016Targeting RIP3-mediated Necroptosis for Chemosensitization1R21CA193633-01A1LIN, YONGLOVELACE BIOMEDICAL & ENVIRONMENTAL RESEARCH INSTITUTE, NM$278,415ZCA1
2016Regulation of multiple myeloma by S100A9 protein1R21CA195020-01A1NEFEDOVA, YULIAVOGL, DAN TOBYWISTAR INSTITUTE, PA$259,949ZCA1
2016Managing chemotherapy induced neuropathy in Cancer patients using ExerGaming1R21CA190933-01A1GARLAND, LINDA LEENAJAFI, BIJANBAYLOR COLLEGE OF MEDICINE, TX$259,412ZCA1
2016Exploiting the ERRalpha/PGC Axis for Cancer Therapy1R21CA190924-01A1LADEROUTE, KEITH R.SRI INTERNATIONAL, CA$258,166ZCA1
2016National trends in end of life care for adolescent and young adult cancer patients1R21CA205309-01WERNLI, KAREN JKAISER FOUNDATION HEALTH PLAN OF WASHINGTON, WA$256,238ZCA1
2016Role of Follicular Dendritic Cells in B lymphoma1R21CA195431-01A1RICKERT, ROBERT CSANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, CA$254,475ZCA1
2016Allosteric inhibition of the SHP2 oncoprotein in breast cancer1R21CA195422-01A1TAUTZ, LUTZSANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, CA$254,475ZCA1
2016Methods for controlling small RNA stability1R21CA201861-01MACRAE, IAN JOHNSCRIPPS RESEARCH INSTITUTE, THE, CA$251,213ZCA1
2016Disparities in Abnormal Mammogram Follow-up: Actionable Communication and Care Coordination Strategies1R21CA195429-01A1KARLINER, LEAH SUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$241,316ZCA1
2016Multiplexed exosome analyses with DNA barcoding1R21CA205322-01LEE, HAKHOMASSACHUSETTS GENERAL HOSPITAL, MA$239,828ZCA1
2016Proton minibeams: Overcoming proton beams’ inability to spare superficial tissues1R21CA191818-01A1DILMANIAN, F AVRAHAMELEY, JOHN G.KRISHNAN, SUNILUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$235,488ZCA1
2016Symptom progress and adverse health outcomes in adult childhood cancer survivors1R21CA202210-01HUANG, I-CHANKRULL, KEVIN RST. JUDE CHILDREN'S RESEARCH HOSPITAL, TN$233,106ZCA1
2016Role of ThPOK in HSC Maintenance and Leukemogenesis1R21CA195356-01A1KAPPES, DIETMAR JSYKES, STEPHEN MATTHEWRESEARCH INST OF FOX CHASE CAN CTR, PA$232,943ZCA1
2016Biological Effects of Systematic Light Exposure For Cancer-Related Fatigue1R21CA195164-01A1REDD, WILLIAM HICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$231,025ZCA1
2016Restoration of lymphatic function in postsurgical lymphedema with lymph node transfer1R21CA194882-01A1MEHRARA, BABAK JSLOAN-KETTERING INST CAN RESEARCH, NY$229,550ZCA1
2016Assessing the impact of differing pharmacy tobacco retail displays on smokers awareness, perceptions, and intentions to quit1R21CA198824-01A1BANSAL-TRAVERS, MAANSIROSWELL PARK CANCER INSTITUTE CORP, NY$227,201ZCA1
2016Minimally invasive image-guided tumor ablation in an oncogenic pig model1R21CA195433-01A1BURDETTE, EVERETTE CRUND, LAURETTAACOUSTIC MEDSYSTEMS, INC., IL$225,795ZCA1
2016Targeting of Tyrosine Phosphatase SHP2 in Myeloproliferative Neoplasms1R21CA202544-01MOHI, GOLAMUPSTATE MEDICAL UNIVERSITY, NY$224,929ZCA1
2016Modeling the impact of mutations in ubiquitin ligase genes on transcriptional programs in endometrial cancer1R21CA205819-01LESLIE, CHRISTINA SSLOAN-KETTERING INST CAN RESEARCH, NY$223,677ZCA1
2016Epigenomic Signatures of Radiation Sensitivity in HPV-associated Cancers1R21CA185921-01A1SHIBATA, DAVIDSIEGEL, ERINUNIVERSITY OF TENNESSEE HEALTH SCI CTR, TN$223,484ZCA1
2016Pancreatic Cyst Fluid miRNOME for Biomarkers of Pancreatic Cancer1R21CA185962-01A1SEN, SUBRATAUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$223,369ZCA1
2016Reprogramming of Prostate Stromal Cells by Prostate Inflammation1R21CA196570-01A1XIN, LIBAYLOR COLLEGE OF MEDICINE, TX$222,296ZCA1
2016Novel Protein Risk Markers for Lung Cancer1R21CA195110-01A1PERERA, FREDERICA PCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$221,850ZCA1
2016Building personalized avatars of human cancer to predict response to therapy1R21CA202540-01HOUVRAS, YARIV JWEILL MEDICAL COLL OF CORNELL UNIV, NY$221,198ZCA1
2016Development of novel RAS inhibitory agents for cancer therapy1R21CA201717-01O'BRYAN, JOHN PUNIVERSITY OF ILLINOIS AT CHICAGO, IL$220,888ZCA1
2016Efficacy of A Behavioral Intervention to Reduce Skin Cancer Risk Among Patients1R21CA196924-01A1MALLETT, KIMBERLY APENNSYLVANIA STATE UNIVERSITY, THE, PA$220,298ZCA1
2016Comparative Effectiveness of Genomics Assay for Active Surveillance Failure Prediction in African American Men: the impact of genetic ancestry and socioeconomic status.1R21CA202552-01MURPHY, ADAM BRYANTNORTHWESTERN UNIVERSITY AT CHICAGO, IL$220,289ZCA1
2016Inhibition of the CMG Helicase as Novel Anti-Neoplastic Approach1R21CA187513-01A1ALEXANDROW, MARK G.H. LEE MOFFITT CANCER CTR & RES INST, FL$219,893ZCA1
2016ANOIKIS EFFECTORS AS DRIVERS OF METASTATIC MELANOMA1R21CA195077-01A1WAJAPEYEE, NARENDRAYALE UNIVERSITY, CT$217,826ZCA1
2016KRas Ligand Development1R21CA201986-01CREWS, CRAIG MYALE UNIVERSITY, CT$217,826ZCA1
2016Surfactant lipids and associated proteins in radiation-induced mucositis1R21CA202751-01LICHTENBERGER, LENARD MUNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX$216,743ZCA1
2016ADAM8 Is a Novel Target for Treatment of Triple-Negative Breast Cancer1R21CA194955-01A1SONENSHEIN, GAIL E.TUFTS UNIVERSITY BOSTON, MA$215,325ZCA1
2016Improving Pediatric Tobacco Control in Primary Care1R21CA192950-01A1MAYS, DARREN MTERCYAK, KENNETHGEORGETOWN UNIVERSITY, DC$214,982ZCA1
2016Improving targeted colorectal cancer screening in the elderly1R21CA191454-01A1LEWIS, CARMEN LYNNUNIVERSITY OF COLORADO DENVER, CO$213,872ZCA1
2016CRISPR/Cas9-based lineage tracing for fate mapping of cancer cells and stem cells1R21CA205825-01LI, ZHEBRIGHAM AND WOMEN'S HOSPITAL, MA$212,575ZCA1
2016Targeting CXCR5 for angioimmunoblastic T-cell lymphoma1R21CA202525-01LOLIS, ELIASYALE UNIVERSITY, CT$212,223ZCA1
2016RPTP domains regulating homodimerization and EGFR activity via heterodimerization1R21CA195158-01A1THEVENIN, DAMIENLEHIGH UNIVERSITY, PA$211,914ZCA1
2016Chemogenomic Profiling of a Novel RNA Polymerase I Inhibitor1R21CA193637-01A1LAIHO, MARIKKIJOHNS HOPKINS UNIVERSITY, MD$211,410ZCA1
2016Longitudinal outcomes of serrated polyps: a population based study1R21CA191651-01A1AMOS, CHRISTOPHER I.BUTTERLY, LYNN FDARTMOUTH COLLEGE, NH$211,410ZCA1
2016Detection of High Grade Prostate Cancer with Subharmonic Ultrasound Imaging1R21CA202214-01FORSBERG, FLEMMINGHALPERN, ETHAN JTHOMAS JEFFERSON UNIVERSITY, PA$209,434ZCA1
2016Mediator Kinases and AML Cell Proliferation1R21CA205912-01OLD, WILLIAM MARLANDTAATJES, DYLAN JUNIVERSITY OF COLORADO, CO$208,967ZCA1
2016KRAS Muations in Plasma cfDNA as Predictor to Erolinib Response in Advanced Pancreatic Cancer1R21CA202487-01LI, DONGHUIOVERMAN, MICHAEL JUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$208,800ZCA1
2016Anti-CTGF Therapy for Squamous Cell Lung Cancer1R21CA201486-01ONAITIS, MARKDUKE UNIVERSITY, NC$207,495ZCA1
2016Metabolic Reprogramming of Colon Cancer Liver Metastasis1R21CA201963-01LOCASALE, JASON W.SHEN, XILINGDUKE UNIVERSITY, NC$207,495ZCA1
2016Hyperpolarized arginine imaging of inflammatory cells and their inhibition in GBM1R21CA201453-01RONEN, SABRINA MIRIAMUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$206,843ZCA1
2016Dissecting the molecular and functional role of Sox2 in synovial sarcoma1R21CA194521-01A1HOCHEDLINGER, KONRADMASSACHUSETTS GENERAL HOSPITAL, MA$206,635ZCA1
2016Chemical biology of superstolides--a novel class of anticancer natural products1R21CA204836-01JIN, ZHENDONGLIU, JUN O.UNIVERSITY OF IOWA, IA$206,296ZCA1
2016Oncogenic role of the ICK-GSK3beta signaling pathway1R21CA195273-01A1FU, ZHENGUNIVERSITY OF VIRGINIA, VA$206,190ZCA1
2016Enhancing the abscopal effect in cancer treatment by immune modulation1R21CA195075-01A1WEICHSELBAUM, RALPH RUNIVERSITY OF CHICAGO, IL$206,190ZCA1
2016Androgen Receptor: A Key Regulator of TRAIL Resistance in Breast Cancer?1R21CA193271-01A1TU, YAPINGCREIGHTON UNIVERSITY, NE$204,515ZCA1
2016Mouse model to study dependence of pancreatic cancer on Pik3ca for progression1R21CA194836-01A1LIN, RICHARD ZSTATE UNIVERSITY NEW YORK STONY BROOK, NY$204,076ZCA1
2016The Ape1-NPM1 Axis and Telomere Maintenance1R21CA191856-01A1DEMPLE, BRUCE F.STATE UNIVERSITY NEW YORK STONY BROOK, NY$204,076ZCA1
2016Evolving Model of Cancer Susceptibility Testing: Clinical Decisions & Outcomes1R21CA194965-01A1PESHKIN, BETH NSCHWARTZ, MARC DGEORGETOWN UNIVERSITY, DC$202,928ZCA1
2016Autophagy regulation of prostate tumor development1R21CA197887-01A1CRAMER, SCOTT DTHORBURN, ANDREW MUNIVERSITY OF COLORADO DENVER, CO$202,928ZCA1
2016Reducing Colorectal Cancer Disparities: Racial Differences in Colorectal Polyp Profile1R21CA202477-01XIRASAGAR, SUDHAUNIVERSITY OF SOUTH CAROLINA AT COLUMBIA, SC$202,741ZCA1
2016Work Ability in Young Adult Surviviors (WAYS): A Quantitative Investigation1R21CA191989-01A1DANHAUER, SUZANNE CWAKE FOREST UNIVERSITY HEALTH SCIENCES, NC$202,275ZCA1
2016A Stepped-Care Telehealth Approach to Treat Distress in Rural Cancer Survivors1R21CA198237-01A1BRENES, GRETCHEN ADANHAUER, SUZANNE CWAKE FOREST UNIVERSITY HEALTH SCIENCES, NC$202,275ZCA1
2016Efficacy of bariatric surgery to decrease the risk of colorectal cancer in mice1R21CA195002-01A1CUMMINGS, BETHANY PAIGECORNELL UNIVERSITY, NY$202,275ZCA1
2016Alternative exercise modalities to improve skeletal muscle function in cancer survivors1R21CA191532-01A1TOTH, MICHAEL JUNIVERSITY OF VERMONT & ST AGRIC COLLEGE, VT$201,460ZCA1
2016Post-transplant Cutaneous Squamous Cell Carcinoma and Macrophage Migration Inhibitory Factor1R21CA198024-01A1OBERYSZYN, TATIANA MOHIO STATE UNIVERSITY, OH$200,970ZCA1
2016Exploring IL-36gamma as a new tumor immune therapy1R21CA205727-01LU, BINFENGUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$200,970ZCA1
2016Immunological miRNA biomarkers for diagnosis of lung cancer1R21CA205746-01JIANG, FENGUNIVERSITY OF MARYLAND BALTIMORE, MD$200,970ZCA1
2016Examining the role of normal hematopoiesis in supporting incipient myelodysplasia1R21CA205828-01PERKINS, ARCHIBALD S.UNIVERSITY OF ROCHESTER, NY$200,807ZCA1
2016A computational framework for statistical analysis of ribosome profiling data1R21CA202960-01LAREAU, LIANA FAYEUNIVERSITY OF CALIFORNIA BERKELEY, CA$200,441ZCA1
2016Carcinoma Cell Hyaluronan as a Therapeutic Target in Metastasis1R21CA205455-01WOOD, DAVID KEVINUNIVERSITY OF MINNESOTA, MN$200,345ZCA1
2016Hedgehog signaling as a tool in the reversal of 5-FU resistance by inhibiting Thymidylate Synthase transcription in colorectal cancer1R21CA202384-01ROBBINS, DAVID JUNIVERSITY OF MIAMI SCHOOL OF MEDICINE, FL$200,318ZCA1
2016Develop and Apply a Novel Genome-wide Mendelian Randomization Method to Examine Relationship between Obesity and Lung Cancer1R21CA202529-01HO, GLORIA YUEN FUNWANG, TAOALBERT EINSTEIN COLLEGE OF MEDICINE, INC, NY$199,967ZCA1
2016Mechanisms of c-CBL Regulation in Cutaneous T-Cell Lymphoma (CTCL)1R21CA206104-01WOOD, GARY SUNIVERSITY OF WISCONSIN-MADISON, WI$199,665ZCA1
2016New HuR inhibitor against pancreatic cancer EMT and CSCs1R21CA198265-01A1CHEN, QIUNIVERSITY OF KANSAS MEDICAL CENTER, KS$199,665ZCA1
2016Novel, orally available ATM inhibitor for glioma conformal radiosensitization1R21CA194789-01A1VALERIE, KRISTOFFER CARLVIRGINIA COMMONWEALTH UNIVERSITY, VA$199,013ZCA1
2016Splicing factors and RNA processing alternations: exploring new players in glioblastoma development1R21CA205475-01PENALVA, LUIZ OTAVIOUNIVERSITY OF TEXAS HLTH SCIENCE CENTER, TX$199,013ZCA1
2016Immunotoxins based on the IgG response to autologous antigens in cancer patients1R21CA198657-01A1DESSAIN, SCOTT KENDALLLANKENAU INSTITUTE FOR MEDICAL RESEARCH, PA$198,997ZCA1
2016Regulation of epithelial-mesenchymal transition and stem cell activity by PTEN in breast cancer1R21CA201715-01LI, SHAOHUARBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL, NJ$198,474ZCA1
2016Rebuilding T cells for Cancer Immunodeficiencies1UH2CA205869-01WALSH, SCOTT TUNIV OF MARYLAND, COLLEGE PARK, MD$198,360ZCA1
2016Second generation MIBG analogs that cotarget DNA for high risk neuroblastoma1R21CA187548-01A1BARANOWSKA-KORTYLEWICZ, JANINAUNIVERSITY OF NEBRASKA MEDICAL CENTER, NE$196,403ZCA1
2016Genetic and Environmental Etiology of Familial Small Intestinal Carcinoid Cancer1R21CA205796-01NEKLASON, DEBORAH WOODUNIVERSITY OF UTAH, UT$196,402ZCA1
2016SIRT5 as a Therapeutic Target in Acute Myeloid Leukemia1R21CA205936-01DEININGER, MICHAEL W.UNIVERSITY OF UTAH, UT$196,402ZCA1
2016Targeting insulin receptor splicing for treatment of rhabdomyosarcoma1R21CA195324-01A1CHANDLER, DAWN SRESEARCH INST NATIONWIDE CHILDREN'S HOSP, OH$196,022ZCA1
2016Predictive cancer biomarkers: Design and analysis of reproducibility studies1R21CA201207-01DOBBIN, KEVIN KSONG, XIAOUNIVERSITY OF GEORGIA, GA$195,750ZCA1
2016Functions of histone variants in castration-resistance prostate cancer1R21CA198820-01A1ISHOV, ALEXANDER MUNIVERSITY OF FLORIDA, FL$195,750ZCA1
2016Statistical Detection and Biochemical Classification of Cancer Driver Mutation Patterns in Biological Networks1R21CA205778-01MOSELEY, HUNTER NATHANIELWANG, CHIUNIVERSITY OF KENTUCKY, KY$195,368ZCA1
2016Role of EMSY protein complexes in the FA DNA repair pathway1R21CA194871-01A1SOBECK, ALEXANDRA THERESIAUNIVERSITY OF MINNESOTA, MN$195,119ZCA1
2016Toward identification of a family of novel NF-kB inducers1R21CA194868-01A1MIYAMOTO, SHIGEKIUNIVERSITY OF WISCONSIN-MADISON, WI$195,054ZCA1
2016Big data approach for correlating gut microbiota with epithelial methylation pattern1R21CA195251-01A1MAI, VOLKERPROSPERI, MATTIAUNIVERSITY OF FLORIDA, FL$194,521ZCA1
2016Fibroblast-macrophage interactions induce a tumor-promoting microenvironment1R21CA185691-01A1KELLY, THOMAS JOSEPHPOST, STEVENUNIV OF ARKANSAS FOR MED SCIS, AR$194,445ZCA1
2016Msi2 regulates the aggressiveness of Non-Small Cell Lung Cancer (NSCLC)1R21CA191425-01A1GOLEMIS, ERICA A.RESEARCH INST OF FOX CHASE CAN CTR, PA$194,119ZCA1
2016BRCA1 interacting proteins important for DNA repair1R21CA198228-01A1FREITAS, MICHAEL A.PARVIN, JEFFREY DOHIO STATE UNIVERSITY, OH$192,514ZCA1
2016Chemoprevention of breast cancer with rexinoids that inhibit obesity-induced metabolic syndrome1R21CA195394-01A1ATIGADDA, VENKATRAM REDDYCORIC, TATJANAUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$191,835ZCA1
2016Developing Therapy for the Treatment of Cholangiocarcinoma1R21CA205501-01YOON, KARINA JUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$191,835ZCA1
2016Engineered Microenvironments to Study Heterogeneity and Stemness in Breast Cancer1R21CA195016-01A1YOON, EUISIKUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$191,765ZCA1
2016Auger Electron Radiotherapy of Late-Stage, Castration-Resistant Prostate Cancer using a Brominated Dihydrotestosterone Analogue1R21CA191913-01A1BEATTIE, BRADLEY JVEACH, DARREN RSLOAN-KETTERING INST CAN RESEARCH, NY$191,291ZCA1
2016Prevention of Depression in Head and Neck Cancer1R21CA197023-01A1IRWIN, SCOTT ACEDARS-SINAI MEDICAL CENTER, CA$190,313ZCA1
2016Cbx-3/HP-1gamma deficiency confers anti-tumor immunity1R21CA198263-01A1THAI, TO-HABETH ISRAEL DEACONESS MEDICAL CENTER, MA$188,138ZCA1
2016High-Throughput Functional Annotation of Fusion Gene Cancer Drivers1R21CA198320-01A1SCOTT, KENNETH L.BAYLOR COLLEGE OF MEDICINE, TX$187,386ZCA1
2016Melanoma suppressing functions of carcinoma oncogene FOXQ11R21CA202162-01NIKIFOROV, MIKHAILROSWELL PARK CANCER INSTITUTE CORP, NY$186,506ZCA1
2016Sphingolipid-Based Anti-Angiogenic Chemosensitization1R21CA198586-01A1KOLESNICK, RICHARD NSLOAN-KETTERING INST CAN RESEARCH, NY$186,398ZCA1
2016Linking macrophages to gut microbiota in obesity-enhanced colon cancer1R21CA191966-01A1MURPHY, ELIZABETH ANGELAROBINSON, CORY MICHAELUNIVERSITY OF SOUTH CAROLINA AT COLUMBIA, SC$185,028ZCA1
2016Defining the Germline Genomic Landscape of a Novel GIST Multi-tumor Syndrome1R21CA192072-01A1SICKLICK, JASON KEITHUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$184,459ZCA1
2016Mechanisms of Orthotopic Human Colorectal Cancer Growth in Immunocompetent Mice1R21CA201829-01LONGMAN, RANDY SWEILL MEDICAL COLL OF CORNELL UNIV, NY$184,331ZCA1
2016Roles of formins in breast cancer invasion1R21CA205262-01HODGSON, LOUISALBERT EINSTEIN COLLEGE OF MEDICINE, INC, NY$181,613ZCA1
2016Telomere dysfunction and genome instability in familial melanoma1R21CA200506-01CHANG, SANDY SYALE UNIVERSITY, CT$181,522ZCA1
2016Measurement of prognostic understanding in patients with advanced cancer1R21CA186932-01A1ROSENFELD, BARRYFORDHAM UNIVERSITY, NY$179,146ZCA1
2016Deep learning for representation of codes used for SEER-Medicare claims research1R21CA202130-01EGLESTON, BRIAN LVUCETIC, SLOBODANRESEARCH INST OF FOX CHASE CAN CTR, PA$178,072ZCA1
2016Advanced Diffusion Imaging of Breast Cancer1R21CA201834-01BOLAN, PATRICK JOHNUNIVERSITY OF MINNESOTA, MN$177,690ZCA1
2016Novel role of the polycomb repressive complex PRC2/EZH2 in glioblastoma1R21CA198648-01A1IYER, VISHWANATH RUNIVERSITY OF TEXAS AT AUSTIN, TX$177,027ZCA1
2016Super-Localization Ultrasound Imaging with Targeted Laser-activated Nanodetectors1R21CA197409-01A1LUKE, GEOFFREY P.DARTMOUTH COLLEGE, NH$176,175ZCA1
2016Defining the urban-rural continuum and distinguishing rural differences to prevent tobacco use1R21CA205589-01STILLMAN, FRANCES ALENAWEWERS, MARY ELLENNATIONAL OPINION RESEARCH CENTER, IL$175,200ZCA1
2016Role of the pentose phosphate pathway in tumorigenesis1R21CA195360-01A1YANG, XIAOLUUNIVERSITY OF PENNSYLVANIA, PA$175,088ZCA1
2016Identifying Mechanisms of p53 and Rb Tumor Suppression In Small Cell Lung Cancer1R21CA205340-01FELDSER, DAVIDUNIVERSITY OF PENNSYLVANIA, PA$174,816ZCA1
2016Molecular origin and evolution of HPV inactive head and neck cancers1R21CA201853-01PIRISI-CREEK, LUCIA AMELIAUNIVERSITY OF SOUTH CAROLINA AT COLUMBIA, SC$174,218ZCA1
2016Novel Point-of-Care Tool to Predict Response to Sorafenib in Hepatocellular Carcinoma1R21CA190945-01A1KASEB, AHMEDUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$174,000ZCA1
2016Couple-based meditation program for patients with metastatic lung cancer and their partners1R21CA191711-01A1MILBURY, KATHRINUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$174,000ZCA1
2016Targeted Molecular Imaging of Cell Death in Ovarian Cancer1R21CA181994-01A1LU, ZHENMILLWARD, STEVEN WUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$174,000ZCA1
2016Defining the role of FAM83A in Herceptin-resistant breast cancer1R21CA194902-01A1JACKSON, MARK W.CASE WESTERN RESERVE UNIVERSITY, OH$172,369ZCA1
2016The cell of origin of breast cancer metastasis1R21CA202227-01LI, YIBAYLOR COLLEGE OF MEDICINE, TX$172,369ZCA1
2016Interferon-beta inhibits the expansion of cancer stem-cells1R21CA198808-01A1JACKSON, MARK W.STARK, GEORGE ROBERTCASE WESTERN RESERVE UNIVERSITY, OH$172,369ZCA1
2016Tumor cytonemes, a new target for tumor suppression1R21CA205580-01KORNBERG, THOMAS B.UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$172,369ZCA1
2016Mechanism by which H2S-producing bacteria influence development of colorectal cancer1R21CA195226-01A1JOBIN, CHRISTIANUNIVERSITY OF FLORIDA, FL$171,275ZCA1
2016Genomic and molecular dissection of the collective invasion pack1R21CA201744-01MARCUS, ADAM I.EMORY UNIVERSITY, GA$169,650ZCA1
2016Restricting radiosensitization through ErbB targeted antibody drug conjugates1R21CA205765-01ADVANI, SUNIL JUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$168,563ZCA1
2016Exploring high-does testosterone as a potential treatment for abiraterone-resistant prostate cancer1R21CA194798-01A1COREY, EVAUNIVERSITY OF WASHINGTON, WA$168,019ZCA1
2016Reducing false positives during interpretations of ultrasound examinations for breast cancer screening1R21CA203684-01GUR, DAVIDUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$167,475ZCA1
2016MicroRNA and Transcription Factor Co-regulation in Cancer1R21CA196508-01A1ZHAO, ZHONGMINGUNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX$167,475ZCA1
2016Unraveling the Function of RNA-Binding proteins in B-lympoblastic Leukemia1R21CA197441-01A1RAO, DINESH SUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$167,475ZCA1
2016Common hTERT Promoter Mutations Represent a Novel Therapeutic Target1R21CA191663-01A1MILLER, DONALD M.UNIVERSITY OF LOUISVILLE, KY$167,023ZCA1
2016A novel IL-2 biologic and tumor immunity1R21CA195334-01A1MALEK, THOMAS RUNIVERSITY OF MIAMI SCHOOL OF MEDICINE, FL$166,931ZCA1
2016Novel Animal Models for Functional Analysis of Protein Phosphorylation in Breast Cancer Progression.1R21CA187303-01A1DAI, ZONGHANTEXAS TECH UNIVERSITY HEALTH SCIS CENTER, TX$166,388ZCA1
2016Searching for Genetic Basis for Metastasis of Differentiated Thyroid Cancer1R21CA201735-01LARGAESPADA, DAVID ANDREWUNIVERSITY OF MINNESOTA, MN$166,243ZCA1
2016Inhibitors of B-raf through the Dimerization Interface1R21CA191899-01A1MCINNES, CAMPBELLUNIVERSITY OF SOUTH CAROLINA AT COLUMBIA, SC$162,984ZCA1
2016A Small-Molecule Inhibitor of the Terminal Steps for Intracrine Androgen Synthesis in Advanced Prostate Cancer1R21CA205108-01MOHLER, JAMES LROSWELL PARK CANCER INSTITUTE CORP, NY$162,075ZCA1
2016Magi2 in aggressive prostate cancer1R21CA195313-01A1MARKER, PAUL CUNIVERSITY OF WISCONSIN-MADISON, WI$161,777ZCA1
2016Modifier of Cancer Sensitivity to Statins1R21CA198327-01A1MU, DAVIDEASTERN VIRGINIA MEDICAL SCHOOL, VA$159,319ZCA1
2016Formation of a Neocentromere at a DSB Site1R21CA205659-01KITAGAWA, KATSUMIRESEARCH INST NATIONWIDE CHILDREN'S HOSP, OH$73,834ZCA1
2016Prevention of genomic instability by a scavenger of bifunctional electrophiles1R21CA201856-01OATES, JOHN ALEXANDERVANDERBILT UNIVERSITY, TN$57,361ZCA1
2016Promoting Smoking Cessation Among Youth Exiting Foster Care1R21CA205190-01BRACISZEWSKI, JORDAN MICHELPACIFIC INSTITUTE FOR RES AND EVALUATION, MD$29,841ZCA1
2016Metabolic regulation of T-ALL cellular proliferation and lifespan1R21CA194829-01A1RATHMELL, JEFFREY C.VANDERBILT UNIVERSITY, TN$20,251ZCA1
2016An epigenetic link from CXCL12-CXCR4 axis through nuclear LASP-1 in breast cancer1R21CA202176-01RAMAN, DAYANIDHIVANDERBILT UNIVERSITY, TN$7,177ZCA1
2016PD-1 Blockade and Neoantigen-Specific T Cell Immunity1R21CA205794-01LINETTE, GERALD PWASHINGTON UNIVERSITY, MO$4,095ZCA1
2015Facilitating Informed Decisions for Contralateral Prophylactic Mastectomy1R21CA187643-01A1KIRSTEIN, LAURIEMANNE, SHARON LRBHS -CANCER INSTITUTE OF NEW JERSEY, NJ$259,496ZCA1
2015Elucidating neural crest-like reprogramming in melanoma1R21CA191742-01FUKUNAGA-KALABIS, MIZUHOWISTAR INSTITUTE, PA$255,511ZCA1
2015eIF2a phosphorylation as a novel druggable target in CRPC1R21CA190588-01KAUFMAN, RANDAL J.WOLF, DIETER ASANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, CA$254,475ZCA1
2015RNF125 controls melanoma response to B-RAF inhibitor and immune checkpoint therapy1R21CA198468-01KIM, HYUNGSOOSANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, CA$254,475ZCA1
2015Single-molecule studies of BRCA1-BACH1 mechanism in genomic integrity1R21CA187612-01A1ROTHENBERG, ELINEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$253,893ZCA1
2015Novel Approach to Facilitate Decisions in Patients w/ Muscle Invasive Bladder CA1R21CA176551-01A1DIEFENBACH, MICHAEL AGALSKY, MATTHEWFEINSTEIN INSTITUTE FOR MEDICAL RESEARCH, NY$252,477ZCA1
2015Diet patterns, aspirin use, obesity and multiple myeloma: a prospective analysis1R21CA198239-01BIRMANN, BRENDA MBRIGHAM AND WOMEN'S HOSPITAL, MA$252,155ZCA1
2015Dissection of Tumor Evolution Using Patient-Derived Xenografts1R21CA191848-01A1CHUANG, JEFFREY HSU-MINJACKSON LABORATORY, ME$251,699ZCA1
2015Computational pathology to predict breast cancer risk in benign breast disease1R21CA187642-01A1BECK, ANDREW HTAMIMI, RULLA MBETH ISRAEL DEACONESS MEDICAL CENTER, MA$247,844ZCA1
2015Salivary Metabolite Biomarkers for Diagnosing Nodal Metastasis in Oral Cancer1R21CA187151-01A1CHEN, CHUFRED HUTCHINSON CANCER RESEARCH CENTER, WA$247,399ZCA1
2015Development of a Novel System to Capture DNA-associated Proteins1R21CA195012-01LAZZERINI DENCHI, EROSSCRIPPS RESEARCH INSTITUTE, THE, CA$247,298ZCA1
2015Antibody Fingerprinting of Triple Negative Breast Cancer by High Throughput FACS1R21CA198595-01FELDING, BRUNIE H.SMIDER, VAUGHN VASILSCRIPPS RESEARCH INSTITUTE, THE, CA$247,298ZCA1
2015Genomic studies for understanding etiology of esophageal adenocarcinoma1R21CA197502-01DAI, JAMESFRED HUTCHINSON CANCER RESEARCH CENTER, WA$246,080ZCA1
2015LMTK3 inhibitors for the treatment of breast cancer1R21CA191351-01A1NEFZI, ADELPIEDRAFITA, FRANCISCO JAVIERTORREY PINES INST FOR MOLECULAR STUDIES, FL$239,730ZCA1
2015Novel Role of Honokiol in Preventing Cancer during Immune Suppression1R21CA191735-01A1PAL, SOUMITROBOSTON CHILDREN'S HOSPITAL, MA$236,488ZCA1
20155-hydroxymethylcytosine in HPV(+) and HPV(-) oral and oropharyngeal cancers1R21CA187537-01A1SARTOR, MAUREEN AGNESUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$235,466ZCA1
2015TDG as a novel target to enhance gemcitabine killing of pancreatic cancer cells1R21CA191956-01A1BELLACOSA, ALFONSOYEN, TIMOTHYRESEARCH INST OF FOX CHASE CAN CTR, PA$232,943ZCA1
2015Resting-state fMRI for Language Mapping in Brain Tumor Patients1R21CA198740-01GOLBY, ALEXANDRA JTIE, YANMEIBRIGHAM AND WOMEN'S HOSPITAL, MA$231,474ZCA1
2015Local control of anti-tumor/anti-self reactivity in low-affinity ACT1R21CA192246-01SCHOENBERGER, STEPHEN PHILIPLA JOLLA INSTITUTE FOR IMMUNOLOGY, CA$230,985ZCA1
2015Influence of germ line genetic variation on myeloma progression and survival1R21CA191896-01VACHON, CELINE MZIV, ELADUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$230,502ZCA1
2015Defining oncogenic capacities of PAK7 mutations in human cancer1R21CA184656-01A1HANSEN, STEEN HENNINGBOSTON CHILDREN'S HOSPITAL, MA$230,333ZCA1
2015Identifying CDK4 and CDK6 substrates in cancers and cancer therapy1R21CA187324-01A1CLURMAN, BRUCE EFRED HUTCHINSON CANCER RESEARCH CENTER, WA$229,680ZCA1
2015Function-blocking anti-ADAM protease antibodies for inhibition of tumorigenesis1R21CA185930-01A1NIKOLOV, DIMITAR BSLOAN-KETTERING INST CAN RESEARCH, NY$229,550ZCA1
2015Defining a novel subtype of luminal-TP53 mutant breast cancer with poor prognosis1R21CA195365-01REIS-FILHO, JORGESHEN, RONGLAIWEIGELT, BRITTASLOAN-KETTERING INST CAN RESEARCH, NY$229,550ZCA1
2015The derivation of pituitary cells from human ES cells1R21CA176700-01A1TABAR, VIVIANESLOAN-KETTERING INST CAN RESEARCH, NY$229,550ZCA1
2015Genetic Predictors of Response to mTOR inhibitors in advanced Renal Cancer1R21CA191687-01CHOUEIRI, TONIKWIATKOWSKI, DAVID J.DANA-FARBER CANCER INST, MA$229,296ZCA1
2015Safety and anti-cancer efficacy of FACT inactivation in mice1R21CA198395-01GUROVA, KATERINA VROSWELL PARK CANCER INSTITUTE CORP, NY$229,028ZCA1
2015Investigation of systemic lymphatic uptake of macromolecules1R21CA191979-01PAPISOV, MIKHAIL IMASSACHUSETTS GENERAL HOSPITAL, MA$227,070ZCA1
2015Internet-Assisted Cognitive Behavior Intervention for Targeted Therapy Fatigue1R21CA191594-01JACOBSEN, PAUL BH. LEE MOFFITT CANCER CTR & RES INST, FL$224,936ZCA1
20154C and Genome Editing for Causal SNP and Gene Discovery at Cancer Risk Loci1R21CA191725-01A1FREEDMAN, MATTHEW LDANA-FARBER CANCER INST, MA$223,181ZCA1
2015Novel therapeutic strategies targeting conformational plasticity of type I MAGE1R21CA191898-01CHO, HEARN JAYOSMAN, ROMANICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$223,096ZCA1
2015Psoralens and melanoma1R21CA198216-01CHO, EUNYOUNGBROWN UNIVERSITY, RI$221,938ZCA1
2015Autophagy, mTOR inhibitors and phenformin in hepatocellular carcinoma1R21CA191814-01A1MERCER, CAROLUNIVERSITY OF CINCINNATI, OH$221,653ZCA1
2015Melanoma prevention by MC1R selective small peptide analogs of alpha MSH1R21CA191761-01A1ABDEL-MALEK, ZALFAUNIVERSITY OF CINCINNATI, OH$221,595ZCA1
2015Ephrin and Eph regulation of prostate stem cells - Resubmission - 11R21CA175834-01A1MOSCATELLI, DAVID ANEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$221,198ZCA1
2015Rapid Determination of Phenotypic Responses Across Cancer Cell Lines1R21CA198543-01POSSEMATO, RICHARD LEWISNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$221,198ZCA1
2015Prevention of COX-2 Derived DNA and Histone Modifications in Cancer1R21CA187495-01A1OATES, JOHN ALEXANDERVANDERBILT UNIVERSITY, TN$221,049ZCA1
2015Translocations And Their Widespread Impact on Gene Regulation1R21CA188968-01A1SKOK, JANE AMANDANEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$220,825ZCA1
2015TBK1 mediated regulation of E2F1 as a therapeutic target in non-small cell lung cancer1R21CA187795-01A1CHELLAPPAN, SRIKUMAR P.H. LEE MOFFITT CANCER CTR & RES INST, FL$219,893ZCA1
2015Specific skeletal targeting of MMP-2 for the treatment of multiple myeloma1R21CA191981-01A1HAZLEHURST, LORI ALYNCH, CONOR CH. LEE MOFFITT CANCER CTR & RES INST, FL$219,893ZCA1
2015Development of the Malignancy-Risk Gene Signature Assay for Predicting Breast Cancer Risk1R21CA198762-01LEE, MARIE CATHERINEH. LEE MOFFITT CANCER CTR & RES INST, FL$219,893ZCA1
2015CUTTING EDGE LINEAGE TRACKING OF TUMOR-EDUCATED IMMUNE CELLS1R21CA191428-01KRUMMEL, MATTHEW FUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$219,513ZCA1
2015Optimizing risk stratification to manage early stage bladder cancer1R21CA191610-01MCMULLEN, CARMIT KURNNIELSEN, MATTHEW E.KAISER FOUNDATION RESEARCH INSTITUTE, CA$219,261ZCA1
2015Pediatric Cancer Interdisciplinary Team Training for Regoaling CARE Discussions1R21CA198049-01FEUDTNER, JOHN CHRISCHILDREN'S HOSP OF PHILADELPHIA, PA$219,240ZCA1
2015Imaging endogenously produced tumor derived micro vesicles1R21CA190344-01PITTET, MIKAELMASSACHUSETTS GENERAL HOSPITAL, MA$218,257ZCA1
2015Targeting an MT1-MMP/MMP2 axis in melanoma by a novel MT1-MMP/MMP2 inhibitor1R21CA187695-01A1BEDOGNI, BARBARACASE WESTERN RESERVE UNIVERSITY, OH$217,926ZCA1
2015Oxygen Microbubbles for Overcoming Hypoxic Tumor Resistance to Radiotherapy1R21CA190926-01A1EISENBREY, JOHNO'KANE, PATRICKTHOMAS JEFFERSON UNIVERSITY, PA$217,689ZCA1
2015Metabolic Drivers of Melanoma Initiation, Progression and Therapy Response1R21CA191364-01WAJAPEYEE, NARENDRAYALE UNIVERSITY, CT$217,283ZCA1
2015Progesterone Augmentation for Smoking Cessation in Women1R21CA198187-01SOFUOGLU, MEHMETYONKERS, KIMBERLY AYALE UNIVERSITY, CT$217,283ZCA1
2015SYNERGIZING PRO-APOPTOTIC AND CAR-T CELL IMMUNOTHERAPY FOR MANTLE CELL LYMPHOMA1R21CA198561-01KATZ, SAMUEL GYALE UNIVERSITY, CT$217,283ZCA1
2015A Problem-Solving Intervention for Family Caregivers in Palliative Oncology1R21CA191165-01A1WASHINGTON, KARLAUNIVERSITY OF MISSOURI-COLUMBIA, MO$217,280ZCA1
2015The genetics of hepatosplenic T cell lymphoma1R21CA195173-01DAVE, SANDEEPDUKE UNIVERSITY, NC$217,108ZCA1
2015Adjuvant Lorazepam for Agitated Delirium in the Palliative Care Unit1R21CA186000-01A1HUI, DAVIDUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$216,664ZCA1
2015Detection of 5-hmC as a Novel Screening Biomarker for Pancreatic Cancer1R21CA187869-01A1HOU, LIFANGZHANG, WEINORTHWESTERN UNIVERSITY AT CHICAGO, IL$216,485ZCA1
2015T cell TGF-beta signaling as a therapeutic target for pediatric brain tumors1R21CA178605-01A1TOWN, TERRENCE CUNIVERSITY OF SOUTHERN CALIFORNIA, CA$215,325ZCA1
2015Therapeutic targeting of the B-cell lymphoma associated mutation MYD88-L265P1R21CA191726-01SNYDER, GREG ALLENUNIVERSITY OF MARYLAND BALTIMORE, MD$215,284ZCA1
2015Beneficial effects of Honokiol against liver cancer1R21CA185943-01A1SAXENA, NEERAJ KUMARUNIVERSITY OF MARYLAND BALTIMORE, MD$215,284ZCA1
2015Identification and Targeting Therapy Resistant Osteosarcoma1R21CA185036-01A1MAKI, CARL GRUSH UNIVERSITY MEDICAL CENTER, IL$215,244ZCA1
2015Feasibility of Molecular Cytology for the Management of Barrett's Esophagus1R21CA187753-01A1GODFREY, TONY EBOSTON UNIVERSITY MEDICAL CAMPUS, MA$214,371ZCA1
2015Discoidin Domain Receptors: Novel Players in Pancreatitis and Pancreatic Preneoplasia1R21CA191347-01CRAWFORD, HOWARD C.FRIDMAN, RAFAEL A.WAYNE STATE UNIVERSITY, MI$213,888ZCA1
2015Overcoming the resistance to anti-angiogenesis therapy1R21CA191970-01RAHIMI, NADERBOSTON UNIVERSITY MEDICAL CAMPUS, MA$213,629ZCA1
2015Deciphering the pathogenesis of pediatric high-grade gliomas1R21CA192003-01LI, GUO-MINUNIVERSITY OF KENTUCKY, KY$212,244ZCA1

Showing the 200 most recent of 517 awards.

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