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NIH funding notice PAR-14-267

Outstanding Investigator Award (R35)

Closed on January 7, 2015.

Posted
June 27, 2014
Close date
January 7, 2015
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

62 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $50,930,589 in first-year total cost, median $914,685.

Most frequent study sections

  1. Special Emphasis Panel[ZCA1 GRB-I (M1)]24
  2. Special Emphasis Panel[ZCA1 GRB-P (M1)]19
  3. Special Emphasis Panel[ZCA1 GRB-S (M1)]18
  4. Special Emphasis Panel[ZCA1 GRB-S (M2)]1

Most frequent institutions

  1. DANA-FARBER CANCER INST5
  2. NORTHWESTERN UNIVERSITY AT CHICAGO3
  3. STANFORD UNIVERSITY3
  4. UNIVERSITY OF CALIFORNIA, SAN DIEGO3
  5. UNIVERSITY OF CALIFORNIA, SAN FRANCISCO3
Competing awards under PAR-14-267 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2016Rewired Signaling at the Nexus of Melanoma Metastasis and Resistance1R35CA197465-01RONAI, ZEEV A.SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, CA$1,162,978ZCA1
2016Cancer genes: translating basics to applications1R35CA197582-01VOGT, PETER KSCRIPPS RESEARCH INSTITUTE, THE, CA$1,062,495ZCA1
2016Mucins and immune cell interactions in ovarian cancer pathogenesis & progression1R35CA197605-01CRAMER, DANIEL WILLIAMBRIGHAM AND WOMEN'S HOSPITAL, MA$1,052,893ZCA1
2016Molecular mechanisms of antibody-mediated immunotherapies1R35CA196620-01RAVETCH, JEFFREY VICTORROCKEFELLER UNIVERSITY, NY$1,017,000ZCA1
2016Molecular Biology of Oncogenic Papillomaviruses1R35CA197262-01HOWLEY, PETER MHARVARD MEDICAL SCHOOL, MA$1,017,000ZCA1
2016Targeting Mutant KRAS for Cancer Therapy1R35CA197731-01SEBTI, SAID MH. LEE MOFFITT CANCER CTR & RES INST, FL$960,504ZCA1
2016Mechanisms governing metastatic dormancy and reactivation1R35CA197566-01GIANCOTTI, FILIPPO GUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$959,998ZCA1
2016Advancing Cancer Therapy through Ground Breaking Research in Radiation Biology1R35CA197616-01KIRSCH, DAVID GUYDUKE UNIVERSITY, NC$942,807ZCA1
2016New Ways of Targeting K-Ras1R35CA197709-01MCCORMICK, FRANK PATRICKUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$932,874ZCA1
2016Targeting breast cancer stem cells1R35CA197585-01WICHA, MAX S.UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$930,000ZCA1
2016Plastic States Associated with Cellular Stress and Malignancy: Insights for Prevention and Treatment of Lethal Metaplastic Cancers1R35CA197694-01TLSTY, THEA DUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$929,349ZCA1
2016Discovery and Characterization of New Human Cancer Viruses1R35CA197463-01MOORE, PATRICK S.UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$916,710ZCA1
2016Mitochondrial metabolism and ROS regulate cancer1R35CA197532-01CHANDEL, NAVDEEP SNORTHWESTERN UNIVERSITY AT CHICAGO, IL$914,370ZCA1
2016Imaging of Hematologic and Oncologic Disorders1R35CA197701-01ROSS, BRIAN D.UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$889,101ZCA1
2016Molecular basis for dietary chemoprevention1R35CA197707-01CHAPKIN, ROBERT STEPHENTEXAS A&M AGRILIFE RESEARCH, TX$886,177ZCA1
2016IKK/NF-kappaB Signaling in Cancer: Therapy, Resistance, and Tumor Initiating Cells1R35CA197684-01BALDWIN, ALBERT SIDNEYUNIV OF NORTH CAROLINA CHAPEL HILL, NC$848,325ZCA1
2016Metabolic basis of B cell lineage leukemia relapse1R35CA197628-01MÜSCHEN, MARKUSUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$653,813ZCA1
2016Molecular Basis of KSHV oncogenesis1R35CA200422-01JUNG, JAE UUNIVERSITY OF SOUTHERN CALIFORNIA, CA$652,549ZCA1
2016Identification of non-coding RNAs to therapeutically target undruggable pathways in metastatic lung adenocarcinoma and squamous cell carcinoma1R35CA197452-01FLORES, ELSA RUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$100,026ZCA1
2015Combining single cell approaches and a developmental perspective to discover stem cell control circuits and the cellular and molecular bases of cancer heterogeneity1R35CA197687-01WAHL, GEOFFREY MYLESSALK INSTITUTE FOR BIOLOGICAL STUDIES, CA$1,144,825ZCA1
2015Dissecting and Targeting Deregulated Mitochondrial Apoptosis in Human Cancer1R35CA197583-01WALENSKY, LOREN DAVIDDANA-FARBER CANCER INST, MA$1,043,422ZCA1
2015Mechanisms of regulation by RNA in acute myeloid leukemia1R35CA197697-01TENEN, DANIEL GBETH ISRAEL DEACONESS MEDICAL CENTER, MA$1,042,185ZCA1
2015Targeting intratumor heterogeneity in breast cancer1R35CA197623-01POLYAK, KORNELIADANA-FARBER CANCER INST, MA$1,033,067ZCA1
2015How do genome alterations cause human lung cancer?1R35CA197568-01MEYERSON, MATTHEW L.DANA-FARBER CANCER INST, MA$1,025,600ZCA1
2015Psychosocial Approaches to Better Understanding & End-Stage Cancer Care (PROTECT)1R35CA197730-01PRIGERSON, HOLLY GWENWEILL MEDICAL COLL OF CORNELL UNIV, NY$987,075ZCA1
2015Statistical Methods for Analysis of Massive Genetic and Genomic Data in Cancer Research1R35CA197449-01LIN, XIHONGHARVARD SCHOOL OF PUBLIC HEALTH, MA$963,452ZCA1
2015Elucidating the dependencies of tumor initiating and drug-resistant niches in human malignancies by genome- wide molecualr profiling of single cells1R35CA197745-01CALIFANO, ANDREACOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$952,336ZCA1
2015Dynamic Complexity of Brain Tumor Stem Cells1R35CA197718-01RICH, JEREMY NCLEVELAND CLINIC LERNER COM-CWRU, OH$951,000ZCA1
2015Neuroscience-based Interventions for Cancer Risk Behavior Change1R35CA197461-01LERMAN, CARYNUNIVERSITY OF PENNSYLVANIA, PA$950,819ZCA1
2015Oncolytic Polovirus, Immunotoxin, and Checkpoint Inhibitor Therapy of Gliomas1R35CA197264-01BIGNER, DARELL DDUKE UNIVERSITY, NC$948,679ZCA1
2015Cancer and Context1R35CA197571-01MACARA, IAN GVANDERBILT UNIVERSITY, TN$941,316ZCA1
2015Live-cell Activity Architecture in Cancer1R35CA197622-01ZHANG, JINUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$930,000ZCA1
2015Bio-behavioral Research At The Intersection of Cancer and Aging1R35CA197289-01MANDELBLATT, JEANNEGEORGETOWN UNIVERSITY, DC$929,318ZCA1
2015GENOMIC ANALYSIS OF INHERITED BREAST AND OVARIAN CANCER1R35CA197458-01KING, MARY-CLAIREUNIVERSITY OF WASHINGTON, WA$927,000ZCA1
2015Cancer Gene Discovery to Identify Targetable Targets1R35CA197706-01CROCE, CARLO MOHIO STATE UNIVERSITY, OH$924,000ZCA1
2015Transforming The Treatment of Tobacco Use in Health Care: Seizing The Potential of the Electronic Health Record to Deliver Comprehensive Chronic Care Treatment for Smoking1R35CA197573-01FIORE, MICHAEL CUNIVERSITY OF WISCONSIN-MADISON, WI$918,000ZCA1
2015Enhancing Antibody-directed Innate Immunity to Improve Cancer Outcome1R35CA197078-01SONDEL, PAUL MUNIVERSITY OF WISCONSIN-MADISON, WI$917,625ZCA1
2015Molecular Pathogenesis of Acute Myeloid Leukemia1R35CA197561-01LEY, TIMOTHY J.WASHINGTON UNIVERSITY, MO$915,000ZCA1
2015Molecular strategies for early detection and targeting of cancer1R35CA197699-01REYA, TANNISHTHAUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$913,500ZCA1
2015Viral priming and targeting NK cells against solid tumor malignancies1R35CA197292-01MILLER, JEFFREY S.UNIVERSITY OF MINNESOTA, MN$912,000ZCA1
2015Targeted Therapy for Leukemia1R35CA197734-01BYRD, JOHN C.OHIO STATE UNIVERSITY, OH$911,328ZCA1
2015Accelerating Transdisciplinary Epidemiology of Colorectal Cancer1R35CA197735-01OGINO, SHUJIDANA-FARBER CANCER INST, MA$873,481ZCA1
2015Inducing Protein Degradation: A New Pharmaceutical Paradigm1R35CA197589-01CREWS, CRAIG MYALE UNIVERSITY, CT$849,926ZCA1
2015Integrative approaches to elucidate p53 transcriptional networks during carcinogenesis1R35CA197591-01ATTARDI, LAURA DSTANFORD UNIVERSITY, CA$832,842ZCA1
2015The Impact of Mitochondrial Repression and Lipid Accumulation by HIF on Tumor Growth1R35CA197713-01GIACCIA, AMATO J.STANFORD UNIVERSITY, CA$782,337ZCA1
2015Breaking the Obesity-Cancer Link: New Targets and Strategies1R35CA197627-01HURSTING, STEPHEN DUNIV OF NORTH CAROLINA CHAPEL HILL, NC$762,608ZCA1
2015Targeting Mechanistic Subtypes of Neoplastic Disease1R35CA197717-01WHITE, MICHAEL A.UT SOUTHWESTERN MEDICAL CENTER, TX$725,453ZCA1
2015DICE - a natural cancer surveillance mechanism - a new road to cancer therapy1R35CA197450-01PETER, MARCUS E.NORTHWESTERN UNIVERSITY AT CHICAGO, IL$710,694ZCA1
2015Research at the interface of optical and ionizing radiation for innovative cancer imaging and therapy1R35CA197608-01CHERRY, SIMON RUNIVERSITY OF CALIFORNIA AT DAVIS, CA$710,184ZCA1
2015Targeting Nrf2 for Cancer Chemoprevention1R35CA197222-01KENSLER, THOMAS WUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$702,815ZCA1
2015Mediators of cancer cell homeostasis: intervention targets common to diverse types of cancer1R35CA197562-01LAND, HARTMUTUNIVERSITY OF ROCHESTER, NY$677,339ZCA1
2015Decoding and targeting the PI3K-mTOR signaling network in cancer1R35CA197459-01MANNING, BRENDAN D.HARVARD SCHOOL OF PUBLIC HEALTH, MA$655,619ZCA1
2015Mutations of Chromatin and its Modifying Machineries in Malignancies1R35CA197569-01SHILATIFARD, ALINORTHWESTERN UNIVERSITY AT CHICAGO, IL$634,659ZCA1
2015Reversing Cellular immortality in cancer1R35CA197563-01ARTANDI, STEVEN ESTANFORD UNIVERSITY, CA$632,529ZCA1
2015Dissecting Pediatric Brain Tumor Microenvironment to Improve Treatment1R35CA197743-01JAIN, RAKESH K.MASSACHUSETTS GENERAL HOSPITAL, MA$541,032ZCA1
2015The intersection of RNA biology and tumor biology1R35CA197311-01MENDELL, JOSHUA TUT SOUTHWESTERN MEDICAL CENTER, TX$521,828ZCA1
2015DNA Repair and Genomic Instability in Cancer Development and Therapy1R35CA197606-01GAUTIER, JEANCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$492,802ZCA1
2015Overcoming resistance to targeted therapy in cancer1R35CA197737-01GARRAWAY, LEVI A.DANA-FARBER CANCER INST, MA$473,472ZCA1
2015Targeting Tumor Suppressive Pathways for Cancer Therapy1R35CA197529-01PANDOLFI, PIER PAOLOBETH ISRAEL DEACONESS MEDICAL CENTER, MA$430,779ZCA1
2015The mTOR and Hippo pathway in cell growth and cancer1R35CA196878-01GUAN, KUN-LIANGUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$414,749ZCA1
2015Immuno-Targeted Therapy for Melanoma1R35CA197633-01RIBAS, ANTONIUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$409,323ZCA1
2015Therapeutic Targeting of Malignant Glioma Stem Cells1R35CA197725-01LESNIAK, MACIEJ SUNIVERSITY OF CHICAGO, IL$85,602ZCA1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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