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NIH funding notice PAR-14-284

High Throughput Screening (HTS) to Discover Chemical Probes (R01)

Closed on September 7, 2017.

Posted
July 17, 2014
Close date
September 7, 2017
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

32 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $15,338,239 in first-year total cost, median $419,997.

Most frequent study sections

  1. Special Emphasis Panel[ZRG1 BST-F (55)]18
  2. Special Emphasis Panel[ZRG1 BST-C (55)]8
  3. Special Emphasis Panel[ZRG1 BST-U (55)]5
  4. Special Emphasis Panel[ZRG1-BST-F(55)R]1

Most frequent institutions

  1. MAYO CLINIC ROCHESTER3
  2. SCRIPPS FLORIDA2
  3. SCRIPPS RESEARCH INSTITUTE, THE2
  4. BROAD INSTITUTE, INC.1
  5. DARTMOUTH COLLEGE1
Competing awards under PAR-14-284 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2018Discovery of Novel Drugs that Increase Tau Clearance to Treat Alzheimer's Disease1RF1AG058447-01FINKBEINER, STEVEN MJ. DAVID GLADSTONE INSTITUTES, CA$1,818,228ZRG1
2018High-Throughput Screens for CaV3.3 Selective T-type Calcium Channel Modulators1R01MH115045-01COTTRELL, JEFFREY RICHARDPAN, JEN QIANBROAD INSTITUTE, INC., MA$831,226ZRG1
2018Screening for fibroblast-selective inhibitors of YAP/TAZ1R56AG058699-01HEYNEN-GENEL, SUSANNETSCHUMPERLIN, DANIEL J.MAYO CLINIC ROCHESTER, MN$457,250ZRG1
2018High Throughput Screen to Discover Modulators of TREM2 Activity1R01AG058446-01A1JACKSON, MICHAELSANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, CA$439,040ZRG1
2018HTS for discovery of inhibitors of the centrosome-independent mitotic spindle machinery1R01CA221978-01ROTH, MICHAEL GUT SOUTHWESTERN MEDICAL CENTER, TX$370,575ZRG1
2018Quantitative High Throughput Screening for Small Molecules Targeting CD47 in Cancer1U01CA218259-01A1MILLER, THOMAS WPARADIGM SHIFT THERAPEUTICS, LLC, CA$336,343ZRG1
2017Small Molecule Discovery for Particulate Guanylyl Cyclase Receptor B Enhancers1R01AG056315-01BURNETT, JOHN CMALANY, SIOBHANSANGARALINGHAM, SASANTHA JESONMAYO CLINIC ROCHESTER, MN$645,210ZRG1
2017Targeting Kinesin Family Member 15 for the Treatment of Cancer1R01CA214545-01GODWIN, ANDREW K.ROY, ANURADHASCHOENEN, FRANKUNIVERSITY OF KANSAS MEDICAL CENTER, KS$641,589ZRG1
2017Limiting undesirable effects of opioids by targeting neuronal RGS complexes1R01DA042746-01A1MARTEMYANOV, KIRILL A.SCAMPAVIA, LOUIS DANIELSCRIPPS FLORIDA, FL$480,000ZRG1
2017High throughput screening to discover inhibitors for IP6K1 as a potential treatment for psychiatric disorders1U01MH112658-01A1WEI, HUIJUNLIEBER INSTITUTE, INC., MD$456,500ZRG1
2017Small Molecule inhibitors of late endosomal pro-inflammatory signaling1R01AR070837-01CATZ, SERGIO DANIELROSEN, HUGHSCRIPPS RESEARCH INSTITUTE, THE, CA$425,700ZRG1
2017Triple-exon Reporter HTS Screen: Discovery of Novel Pre-mRNA Splicing Modulators1R01CA214759-01WEBB, THOMAS ROYSRI INTERNATIONAL, CA$417,929ZRG1
2017High content in vivo screening for acute kidney injury ameliorating drugs1R01DK112652-01HUKRIEDE, NEIL AVOGT, ANDREASUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$348,188ZRG1
2017Using HTS to Identify Inhibitors of R155H-p97/VCP Mutant to treat IBMPFD/ALS1R01NS100815-01CHOU, TSUI-FENLUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER, CA$329,000ZRG1
2016High Throughput Screening to Discover Small Molecule Modulators of the Orphan GPCR GPR1511R01MH111116-01BANNISTER, THOMAS DMCDONALD, PATRICIA HELENSCRIPPS FLORIDA, FL$870,985ZRG1
2016High Throughput Screening to Discover Chemical Inhibitors of Quiescin Sulfhydryl Oxidase 11R01CA201226-01A1FAIGEL, DOUGLASSERGIENKO, EDUARD A.MAYO CLINIC ARIZONA, AZ$633,669ZRG1
2016High-Throughput Screening for Dab2 Inhibitors as Stabilizers of CFTR1R01DK104847-01A1MADDEN, DEAN RDARTMOUTH COLLEGE, NH$550,884ZRG1
2016Identification of Small Molecules that Influence Trafficking of the GnRH Receptor1R01DK103591-01A1CONN, P. MICHAELSCAMPAVIA, LOUIS DANIELTEXAS TECH UNIVERSITY HEALTH SCIS CENTER, TX$514,347ZRG1
2016High-Throughput screening for inhibitors of neuroinflammatory lipid production1R01NS092980-01A1CRAVATT, BENJAMIN FSCAMPAVIA, LOUIS DANIELSCRIPPS RESEARCH INSTITUTE, THE, CA$493,260ZRG1
2016High Throughput Screen to Identify Inhibitors of the Golgi GOLPH3 Pathway1R01CA201303-01FIELD, SETH JUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$423,213ZRG1
2016Discovery of novel small molecule antidepressants1R01MH106511-01A1CHETKOVICH, DANE MSCHILTZ, GARY ENORTHWESTERN UNIVERSITY AT CHICAGO, IL$386,250ZRG1
2016Identifying CXCR4 Receptor Agonists to Improve Diabetic Healing1R01DK105010-01A1LIECHTY, KENNETH WUNIVERSITY OF COLORADO DENVER, CO$383,287ZRG1
2016Screening for adjuvant gliobalstoma therapeutics1R01NS095647-01A1TANNOUS, BAKHOS AMASSACHUSETTS GENERAL HOSPITAL, MA$374,063ZRG1
2016A high content screen dissecting ciliogenesis and oncogenic Hedgehog signaling1R01CA181231-01A1ARKIN, MICHELLEREITER, JEREMY FUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$362,569ZRG1
2016Targeting protein-protein interactions of Bmi1 oncoprotein1R01CA201204-01A1GREMBECKA, JOLANTAUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$319,688ZRG1
2016Small molecule agonists of insulin-like3 receptor for treatment of osteoporosis1R01AR070093-01AGOULNIK, ALEXANDER IFLORIDA INTERNATIONAL UNIVERSITY, FL$255,200ZRG1
2016TROY HTS Compound Screening1R01NS092955-01A1TRAN, NHAN LTRANSLATIONAL GENOMICS RESEARCH INST, AZ$22,906ZRG1
2015Small Molecule Discovery for GC-A Activators1R01DK103850-01A1BURNETT, JOHN CMAYO CLINIC ROCHESTER, MN$422,064ZRG1
2015Podocyte-based HCS assays for discovering therapeutics against kidney diseases1R01DK106512-01GUPTA, VINEETRUSH UNIVERSITY MEDICAL CENTER, IL$407,500ZRG1
2015High Throughput Screening to Identify Small Molecule Rank Agonists1R01AR068438-01GRIGGS, DAVIDSAINT LOUIS UNIVERSITY, MO$335,419ZRG1
2015High throughput screening (HTS) to discover chemical probes for neutral sphingomyelinase21R01MH107659-01ROJAS, CAMILOJOHNS HOPKINS UNIVERSITY, MD$324,000ZRG1
2015High Throughput Screening to Discover Novel Toxin Inhibitors Relevant to the Treatment of Otitis Media1U01DC014756-01DAINES, DAYLE ANITAOLD DOMINION UNIVERSITY, VA$262,157ZRG1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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